Preliminary assessment of the C13-side chain 2′-hydroxylase involved in Taxol biosynthesis

Biochemical and Biophysical Research Communications

Volumn 338, Issue 1, 2005, Pages 410-417

  Long, Robert M ^a   Croteau, Rodney ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Phenylalanoyl baccatin III 2 hydroxylase; Biosynthesis; Cytochrome P450 oxygenase; N Debenzoyltaxol; Paclitaxel; Side chain assembly; Taxol; Taxus; Yew

Indexed keywords

2' HYDROXYLASE; ACYL COENZYME A; AMINOMUTASE; BACCATIN III; BETA PHENYLALANYL COENZYME A; BETA PHENYLALANYLBACCATIN III; COENZYME A; CYTOCHROME P450; ISOENZYME; OXYGENASE; PACLITAXEL; PHENYLALANINE; PHENYLISOSERYL COENZYME A; SERINE DERIVATIVE; TAXOID; TERPENOID DERIVATIVE; TRANSFERASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ESTERIFICATION; HYDROXYLATION; IN VIVO STUDY; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; SUSPENSION CELL CULTURE; TAXUS;

CARBON; CELL-FREE SYSTEM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HYDROXYLATION; MIXED FUNCTION OXYGENASES; MODELS, CHEMICAL; MODELS, MOLECULAR; PACLITAXEL; TAXUS;

TAXUS;

EID: 27544457332     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.08.119     Document Type: Article

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