-
1
-
-
17344379513
-
Five years on the wings of fork head
-
Kaufmann, E. & Knochel, W. Five years on the wings of fork head. Mech. Dev. 57, 3-20 (1996).
-
(1996)
Mech. Dev.
, vol.57
, pp. 3-20
-
-
Kaufmann, E.1
Knochel, W.2
-
2
-
-
0024973841
-
The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo
-
Weigel, D., Jurgens, G., Kuttner, R, Seifert, E, & Jackle, H. The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell 57, 645-658 (1989).
-
(1989)
Cell
, vol.57
, pp. 645-658
-
-
Weigel, D.1
Jurgens, G.2
Kuttner, R.3
Seifert, E.4
Jackle, H.5
-
3
-
-
0025162339
-
HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally
-
La, E., Prezioso, V. R., Smith, E., Litvin, O., Costa, R. H. & Darnel, J. E. HNF-3A, a hepatocyte-enriched transcription factor of novel structure is regulated transcriptionally. Genes Dev. 4, 1427-1436 (1990).
-
(1990)
Genes Dev.
, vol.4
, pp. 1427-1436
-
-
La, E.1
Prezioso, V.R.2
Smith, E.3
Litvin, O.4
Costa, R.H.5
Darnel, J.E.6
-
4
-
-
0342614209
-
Unified nomenclature for the winged helix/forkhead transcription factors
-
Kaestner, K. H., Knochel, W. & Martinez, D. E. Unified nomenclature for the winged helix/forkhead transcription factors. Genes Dev. 14, 142-146 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 142-146
-
-
Kaestner, K.H.1
Knochel, W.2
Martinez, D.E.3
-
5
-
-
0027270989
-
Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H 5
-
Clark, K. L., Halay, E. D., Lai, E. & Burley, S. K. Co-crystal structure of the HNF-3/fork head DNA-recognition motif resembles histone H5. Nature 364, 412-420 (1993).
-
(1993)
Nature
, vol.364
, pp. 412-420
-
-
Clark, K.L.1
Halay, E.D.2
Lai, E.3
Burley, S.K.4
-
6
-
-
0037866671
-
Fox's in development and disease
-
Lehmann, O. J., Sowden, J. C., Cartsson, P., Jordan, T. & Bhattacharya, S. S. Fox's in development and disease. Trends Genet. 19, 339-344 (2003).
-
(2003)
Trends Genet.
, vol.19
, pp. 339-344
-
-
Lehmann, O.J.1
Sowden, J.C.2
Cartsson, P.3
Jordan, T.4
Bhattacharya, S.S.5
-
7
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K. J. & Powrie, F. Regulatory T cells in the control of immune pathology. Nature Immunol. 2, 816-822 (2001).
-
(2001)
Nature Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
8
-
-
0036597371
-
+ suppressor T cells: More questions than answers
-
+ suppressor T cells: more questions than answers Nature Rev. Immunol. 2, 389-400 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
9
-
-
0028171297
-
+ T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse
-
+ T cells are the effector cells in disease pathogenesis in the scurfy (sf) mouse. J. Immunol. 153, 3764-3774 (1994).
-
(1994)
J. Immunol.
, vol.153
, pp. 3764-3774
-
-
Blair, P.J.1
-
10
-
-
0026043866
-
Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: Potential model for thymic education
-
Godfrey, V. L., Wilkinson, J. E., Rinchik, E. M. & Russell, L. B. Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for thymic education. Proc. Natl Acad. Sci. USA 88, 5528-5532 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 5528-5532
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Rinchik, E.M.3
Russell, L.B.4
-
11
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferatrve disorder of the scurfy mouse
-
Brunkow, M. E. et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferatrve disorder of the scurfy mouse. Nature Genet. 27, 68-73 (2001). This study identified the gene that is defective in scurfy mice by combining high-resolution genetic and physical mapping with large-scale sequence analysis. Genetic complementation showed that the protein product of Foxp3 is essential for normal immune homeostasis.
-
(2001)
Nature Genet.
, vol.27
, pp. 68-73
-
-
Brunkow, M.E.1
-
12
-
-
0041931076
-
Foxp3 and natural regulatory T cells: Key to a cell lineage?
-
Ramsdell, F. Foxp3 and natural regulatory T cells: key to a cell lineage? Immunity 19, 165-168 (2003).
-
(2003)
Immunity
, vol.19
, pp. 165-168
-
-
Ramsdell, F.1
-
13
-
-
0035163909
-
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
-
Wildin, R. S. et al. X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy. Nature Genet. 27, 18-20 (2001).
-
(2001)
Nature Genet.
, vol.27
, pp. 18-20
-
-
Wildin, R.S.1
-
14
-
-
0035167967
-
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP 3
-
Bennett, C. L. et al. The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3. Nature Genet. 27, 20-21 (2001).
-
(2001)
Nature Genet.
, vol.27
, pp. 20-21
-
-
Bennett, C.L.1
-
15
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila, T. A. et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J. Clin. Invest. 106, R75-R81 (2000).
-
(2000)
J. Clin. Invest.
, vol.106
-
-
Chatila, T.A.1
-
18
-
-
0035576221
-
The amount of scurfin protein determines peripheral T cell number and responsiveness
-
Khattri, R. et al. The amount of scurfin protein determines peripheral T cell number and responsiveness. J. Immunol. 167, 6312-6320 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 6312-6320
-
-
Khattri, R.1
-
19
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L. & Powrie, F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation, J. Exp. Med. 190, 995-1004 (1999).
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
20
-
-
0035813231
-
Scurfin (FOXP3) acts as a represser of transcription and regulates T cell activation
-
Schubert, L. A., Jeffery, E., Zhang, Y., Ramsdell, F. & Ziegler, S. F. Scurfin (FOXP3) acts as a represser of transcription and regulates T cell activation. J. Biol. Chem. 276, 37672-37679 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37672-37679
-
-
Schubert, L.A.1
Jeffery, E.2
Zhang, Y.3
Ramsdell, F.4
Ziegler, S.F.5
-
23
-
-
0035801335
-
+ regulatory T cells is mediated by cell surface-bound transforming growth factor β
-
+ regulatory T cells is mediated by cell surface-bound transforming growth factor β. J. Exp. Med. 194, 629-644 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
24
-
-
0348223787
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp 3
-
+ regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198, 1875-1886 (2003).
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
-
25
-
-
2142645808
-
- T eels through Foxp3 induction and down-regulation of Smad7
-
- T cells through the induction of FOXP3 expression, which can subsequently inhibit SMAD7 and thereby activate a positive autoregulatory loop of TGF-β signalling.
-
(2004)
J. Immunol.
, vol.172
, pp. 5149-5153
-
-
Fantini, M.C.1
-
27
-
-
2942627115
-
- regulatory T cells independent of autocrine TGF-β 1
-
- regulatory T cells independent of autocrine TGF-β1. Blood 103, 4594-4601 (2004).
-
(2004)
Blood
, vol.103
, pp. 4594-4601
-
-
Mamura, M.1
-
28
-
-
4043071317
-
+ regulatory T cell compartment
-
+ regulatory T cell compartment. J. Immunol. 173, 2227-2230 (2004).
-
(2004)
J. Immunol.
, vol.173
, pp. 2227-2230
-
-
Polanczyk, M.J.1
-
29
-
-
1842631137
-
Developing a new paradigm for thymus organogenesis
-
Blackburn, C. C. & Manley, N. R. Developing a new paradigm for thymus organogenesis. Nature Rev. Immunol. 4, 278-289 (2004).
-
(2004)
Nature Rev. Immunol.
, vol.4
, pp. 278-289
-
-
Blackburn, C.C.1
Manley, N.R.2
-
30
-
-
0028000121
-
New member of the winged-helix protein family disrupted in mouse and rat nude mutations
-
Nehls, M., Rfeifer, D., Schorpp, M., Hedrich, H. & Boehm, T. New member of the winged-helix protein family disrupted in mouse and rat nude mutations. Nature 372, 103-107 (1994).
-
(1994)
Nature
, vol.372
, pp. 103-107
-
-
Nehls, M.1
Rfeifer, D.2
Schorpp, M.3
Hedrich, H.4
Boehm, T.5
-
31
-
-
0034844763
-
Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product
-
Bleul, C. C. & Boehm, T. Laser capture microdissection-based expression profiling identifies PD1-ligand as a target of the nude locus gene product. Eur. J. Immunol. 31, 2497-2503 (2001).
-
(2001)
Eur. J. Immunol.
, vol.31
, pp. 2497-2503
-
-
Bleul, C.C.1
Boehm, T.2
-
32
-
-
0034610980
-
Facilitation of β selection and modification of positive selection in the thymus of PD-1-deficient mice
-
Nishimura, H., Honjo, T. & Minato, N. Facilitation of β selection and modification of positive selection in the thymus of PD-1-deficient mice. J. Exp. Med. 191, 891-898 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 891-898
-
-
Nishimura, H.1
Honjo, T.2
Minato, N.3
-
33
-
-
0036852151
-
Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice
-
Balclunaite, G. et al. Wnt glycoproteins regulate the expression of FoxN1, the gene defective in nude mice. Nature Immunol. 3, 1102-1108 (2002). This paper reported that secreted WNT glycoproteins expressed by TECs and thymocytes can regulate FOXN1 expression in the epithelium through both autocrine and paracrine mechanisms.
-
(2002)
Nature Immunol.
, vol.3
, pp. 1102-1108
-
-
Balclunaite, G.1
-
34
-
-
0345689338
-
BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis
-
Tsai, P. T., Lee, R. A. & Wu, H. BMP4 acts upstream of FGF in modulating thymic stroma and regulating thymopoiesis, Blood 102, 3947-3953 (2003).
-
(2003)
Blood
, vol.102
, pp. 3947-3953
-
-
Tsai, P.T.1
Lee, R.A.2
Wu, H.3
-
36
-
-
0036174684
-
Role of the nude gene in epithelial terminal differentiation
-
Baxter, R. M. & Brissette, J. L. Role of the nude gene in epithelial terminal differentiation. J. Invest. Dermatol. 118, 303-309 (2002).
-
(2002)
J. Invest. Dermatol.
, vol.118
, pp. 303-309
-
-
Baxter, R.M.1
Brissette, J.L.2
-
37
-
-
0242624627
-
A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation
-
Su, D. M., Navarre, S., Oh, W. J., Condie, B. G. & Manley, N. R. A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation. Nature Immunol. 4, 1128-1135 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 1128-1135
-
-
Su, D.M.1
Navarre, S.2
Oh, W.J.3
Condie, B.G.4
Manley, N.R.5
-
38
-
-
0034601695
-
Formation of regulator/target gene relationships during evolution
-
Schlake, T., Schorpp, M. and Boehm, T. Formation of regulator/target gene relationships during evolution. Gene 256, 29-34 (2000).
-
(2000)
Gene
, vol.256
, pp. 29-34
-
-
Schlake, T.1
Schorpp, M.2
Boehm, T.3
-
39
-
-
0029013302
-
Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium
-
Hackett, B.P. et al. Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium. Proc. Natl Acad. Sci. USA 92, 4249-4253 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 4249-4253
-
-
Hackett, B.P.1
-
40
-
-
0028051755
-
Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter
-
Clevidence, D. E. et al. Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter. Dev. Biol. 166, 195-209 (1994).
-
(1994)
Dev. Biol.
, vol.166
, pp. 195-209
-
-
Clevidence, D.E.1
-
41
-
-
0030967651
-
The winged helix transcription factor HFH- 4 is expressed during choroid plexus epithelial development in the mouse embryo
-
Lim, L., Zhou, H. & Costa, R. H. The winged helix transcription factor HFH-4 is expressed during choroid plexus epithelial development in the mouse embryo. Proc. Natl Acad. Sci. USA 94, 3094-3099 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3094-3099
-
-
Lim, L.1
Zhou, H.2
Costa, R.H.3
-
42
-
-
0032530312
-
Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry
-
Chen, J., Knowles, H. J., Hebert, J. L. & Hackett, B. P. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J. Clin. Invest. 102, 1077-1082(1998).
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1077-1082
-
-
Chen, J.1
Knowles, H.J.2
Hebert, J.L.3
Hackett, B.P.4
-
43
-
-
0033901391
-
Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice
-
Brody, S. L., Van, X. H., Wuerffel, M. K., Song, S. K. & Shapiro, S. D. Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice. Am. J. Respir. Cell. Mol. Biol. 23, 43-51 (2000).
-
(2000)
Am. J. Respir. Cell. Mol. Biol.
, vol.23
, pp. 43-51
-
-
Brody, S.L.1
Van, X.H.2
Wuerffel, M.K.3
Song, S.K.4
Shapiro, S.D.5
-
44
-
-
1142286333
-
H1 activation and inflammation by the NF-κB repressor Foxj1
-
H1 activation and inflammation by the NF-κB repressor Foxj1. Science 303, 1017-1020 (2004). This study showed that FOXJ1 can inhibit NF-κB signalling through induction of IκB proteins. These results indicate that FOXJ1 might modulate inflammatory reactions and prevent autoimmunity by antagonizing the transcription of genes that encode pro-inflammatory cytokines.
-
(2004)
Science
, vol.303
, pp. 1017-1020
-
-
Lin, L.1
Spoor, M.S.2
Gerth, A.J.3
Brody, S.L.4
Peng, S.L.5
-
45
-
-
0030973579
-
Transcription factors of the NFAT family: Regulation and function
-
Rao, A., Luo, C. & Hogan, P. G. Transcription factors of the NFAT family: regulation and function. Annu. Rev. Immunol. 15, 707-747 (1997).
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 707-747
-
-
Rao, A.1
Luo, C.2
Hogan, P.G.3
-
46
-
-
0036781052
-
NF-κB regulation in the immune system
-
Li, Q. & Verma, I. M. NF-κB regulation in the immune system. Nature Rev. Immunol. 2, 725-734 (2002).
-
(2002)
Nature Rev. Immunol.
, vol.2
, pp. 725-734
-
-
Li, Q.1
Verma, I.M.2
-
47
-
-
0033136283
-
An essential role for NF-κB in IL-18-induced IFN-γ expression in KG-1 cells
-
Kojima, H. et al. An essential role for NF-κB in IL-18-induced IFN-γ expression in KG-1 cells. J. Immunol. 162, 5063-5069 (1999).
-
(1999)
J. Immunol.
, vol.162
, pp. 5063-5069
-
-
Kojima, H.1
-
48
-
-
0031281421
-
Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member
-
Brody, S. L., Hackett, B. P. & White, R. A. Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member. Genomics 45, 509-518 (1997).
-
(1997)
Genomics
, vol.45
, pp. 509-518
-
-
Brody, S.L.1
Hackett, B.P.2
White, R.A.3
-
49
-
-
2442542309
-
Extracellular signal-regulated kinases 1/2 function as integrators of TCR signal strength
-
Schade, A. E. & Levine, A. D. Extracellular signal-regulated kinases 1/2 function as integrators of TCR signal strength. J. Immunol. 172, 5828-5832 (2004).
-
(2004)
J. Immunol.
, vol.172
, pp. 5828-5832
-
-
Schade, A.E.1
Levine, A.D.2
-
51
-
-
0038003956
-
Decisions on life and death: FOXO forkhead transcription factors are in command when PKB/Akt is off duty
-
Burgering, B. M. & Medema, R. H. Decisions on life and death: FOXO forkhead transcription factors are in command when PKB/Akt is off duty. J. Leukoc. Biol. 73, 689-701 (2003).
-
(2003)
J. Leukoc. Biol.
, vol.73
, pp. 689-701
-
-
Burgering, B.M.1
Medema, R.H.2
-
52
-
-
0042591476
-
FOXO transcription factors as regulators of immune homeostasis: Molecules to die for?
-
Birkenkamp, K. U. & Coffer, P. J. FOXO transcription factors as regulators of immune homeostasis: molecules to die for? J. Immunol. 171, 1623-1629 (2003).
-
(2003)
J. Immunol.
, vol.171
, pp. 1623-1629
-
-
Birkenkamp, K.U.1
Coffer, P.J.2
-
53
-
-
2342496712
-
FoxOs at the crossroads of cellular metabolism, differentiation, and transformation
-
Accili, D. & Arden, K. C. FoxOs at the crossroads of cellular metabolism, differentiation, and transformation. Cell 117, 421-426 (2004).
-
(2004)
Cell
, vol.117
, pp. 421-426
-
-
Accili, D.1
Arden, K.C.2
-
54
-
-
4143129696
-
H activation, and autoinflammation by the forkhead transcription factor Foxo3a
-
H activation, and autoinflammation by the forkhead transcription factor Foxo3a. Immunity 21, 203-213 (2004). This was the first study that identified a role for FOXO transcription factors in immune homeostasis in vivo. FOXO3A can inhibit NF-κB activation and maintain T-cell tolerance through an undefined mechanism.
-
(2004)
Immunity
, vol.21
, pp. 203-213
-
-
Lin, L.1
Hron, J.D.2
Peng, S.L.3
-
55
-
-
0038152845
-
Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a
-
Castrillon, D. H., Miao, L., Kollipara, R., Horner, J. W. & DePinho, R. A. Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a. Science 301, 215-218 (2003).
-
(2003)
Science
, vol.301
, pp. 215-218
-
-
Castrillon, D.H.1
Miao, L.2
Kollipara, R.3
Horner, J.W.4
DePinho, R.A.5
-
57
-
-
0036120725
-
Control of cell cycle exit and entry by protein kinase B-reguiated forkhead transcription factors
-
Kops, G. J. et al. Control of cell cycle exit and entry by protein kinase B-reguiated forkhead transcription factors. Mol. Cell. Biol. 22, 2025-2036 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2025-2036
-
-
Kops, G.J.1
-
59
-
-
0037136563
-
Forkhead transcription factor FOXO 3a protects quiescent cells from oxidative stress
-
Kops, G. J. et al. Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress. Nature 419, 316-321 (2002).
-
(2002)
Nature
, vol.419
, pp. 316-321
-
-
Kops, G.J.1
-
62
-
-
0037094096
-
Kip1 and Bim in response to IL-2
-
Kip1 and Bim in response to IL-2. J. Immunol. 168, 5024-5031 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 5024-5031
-
-
Stahl, M.1
-
64
-
-
2342483743
-
Phosphoinositide 3-kinase in T cell activation and survival
-
Okkenhaug, K., Bilancio, A., Emery, J. L. & Vanhaesebroeck, B. Phosphoinositide 3-kinase in T cell activation and survival. Biochem. Soc. Trans. 32, 332-335 (2004).
-
(2004)
Biochem. Soc. Trans.
, vol.32
, pp. 332-335
-
-
Okkenhaug, K.1
Bilancio, A.2
Emery, J.L.3
Vanhaesebroeck, B.4
-
65
-
-
2342653278
-
Control of cyclin G2 mRNA expression by forkhead transcription factors; mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead
-
Martinez-Gac, L., Marques, M., Garcia, Z., Campanero, M. R. & Carrera, A. C. Control of cyclin G2 mRNA expression by forkhead transcription factors; mechanism for cell cycle control by phosphoinositide 3-kinase and forkhead. Mol. Cell. Biol. 24, 2181-2189 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2181-2189
-
-
Martinez-Gac, L.1
Marques, M.2
Garcia, Z.3
Campanero, M.R.4
Carrera, A.C.5
-
66
-
-
0030987302
-
Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest
-
Horne, M. C. et al. Cyclin G2 is up-regulated during growth inhibition and B cell antigen receptor-mediated cell cycle arrest J. Biol. Chem. 272, 12650-12661 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12650-12661
-
-
Horne, M.C.1
-
67
-
-
0037017396
-
FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: Protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity
-
Dijkers, P. F. et al. FKHR-L1 can act as a critical effector of cell death induced by cytokine withdrawal: protein kinase B-enhanced cell survival through maintenance of mitochondrial integrity. J. Cell Biol. 156, 531-542 (2002). This paper showed that activation of FOXO3A alone can recapitulate all known elements of the apoptotic programme that are normally induced in lymphocytes by cytokine withdrawal.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 531-542
-
-
Dijkers, P.F.1
-
68
-
-
1642305625
-
H2 cells against activation-induced cell death by a mechanism requiring PI 3 kinase function
-
H2 cells against activation-induced cell death by a mechanism requiring PI3 kinase function. J. Exp. Med. 199, 831-842 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 831-842
-
-
Pandiyan, P.1
-
69
-
-
0034658320
-
L levels in vivo
-
L levels in vivo. J. Exp. Med. 191, 1721-1734 (2000).
-
(2000)
J. Exp. Med.
, vol.191
, pp. 1721-1734
-
-
Jones, R.G.1
-
70
-
-
0037134491
-
The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional represser
-
Tang, T. T. et al. The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional represser. J. Biol. Chem. 277, 14255-14265 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14255-14265
-
-
Tang, T.T.1
-
71
-
-
11144357466
-
IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a
-
Hu, M. C. et al. IκB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a. Cell 117, 225-237 (2004).
-
(2004)
Cell
, vol.117
, pp. 225-237
-
-
Hu, M.C.1
-
72
-
-
0037119628
-
IκB kinase signaling is essential for maintenance of mature B cells
-
Pasparakis, M., Schmidt-Supprian, M. & Rajewsky, K. IκB kinase signaling is essential for maintenance of mature B cells. J. Exp. Med. 196, 743-752 (2002).
-
(2002)
J. Exp. Med.
, vol.196
, pp. 743-752
-
-
Pasparakis, M.1
Schmidt-Supprian, M.2
Rajewsky, K.3
-
73
-
-
2342622123
-
Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factor
-
Yusuf, I., Zhu, X., Kharas, M. G., Chen, J. & Fruman, D. A. Optimal B-cell proliferation requires phosphoinositide 3-kinase-dependent inactivation of FOXO transcription factor. Blood 104, 784-787 (2004).
-
(2004)
Blood
, vol.104
, pp. 784-787
-
-
Yusuf, I.1
Zhu, X.2
Kharas, M.G.3
Chen, J.4
Fruman, D.A.5
-
74
-
-
1642580499
-
FoxO3a regulates erythroid differentiation and induces BTG 1, an activator of protein arginine methyl transferase 1
-
Bakker, W. J. et al., FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1. J. Cell Biol. 164, 175-184 (2004).
-
(2004)
J. Cell Biol.
, vol.164
, pp. 175-184
-
-
Bakker, W.J.1
-
75
-
-
0033535507
-
Exposing the human nude phenotype
-
Frank, J. et al. Exposing the human nude phenotype. Nature 398, 473-474 (1999).
-
(1999)
Nature
, vol.398
, pp. 473-474
-
-
Frank, J.1
-
76
-
-
2442676466
-
FLT3 receptors with internal tandem duplications promote cell viability and proliferation by signaling through Foxo proteins
-
Scheijen, B., Ngo, H. T., Kang, H. & Griffin, J. D. FLT3 receptors with internal tandem duplications promote cell viability and proliferation by signaling through Foxo proteins. Oncogene 23, 3338-3349 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 3338-3349
-
-
Scheijen, B.1
Ngo, H.T.2
Kang, H.3
Griffin, J.D.4
-
77
-
-
0037458609
-
A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells
-
Komatsu, N. et al. A member of Forkhead transcription factor FKHRL1 is a downstream effector of STI571-induced cell cycle arrest in BCR-ABL-expressing cells. J. Biol. Chem. 278, 6411-6419 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6411-6419
-
-
Komatsu, N.1
-
78
-
-
0036651790
-
A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR
-
Ramaswamy, S., Nakamura, N. Sansal, I., Bergeron, L. & Sellers, W. R. A novel mechanism of gene regulation and tumor suppression by the transcription factor FKHR. Cancer Cell 2, 81-91 (2002).
-
(2002)
Cancer Cell
, vol.2
, pp. 81-91
-
-
Ramaswamy, S.1
Nakamura, N.2
Sansal, I.3
Bergeron, L.4
Sellers, W.R.5
-
79
-
-
0036387193
-
Forkhead transcription factors: Key players in development and metabolism
-
Carlsson, P. & Mahlapuu, M. Forkhead transcription factors: key players in development and metabolism. Dev. Biol. 250, 1-23 (2002).
-
(2002)
Dev. Biol.
, vol.250
, pp. 1-23
-
-
Carlsson, P.1
Mahlapuu, M.2
|