The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

Pharmacology and Therapeutics

Volumn 110, Issue 3, 2006, Pages 465-502

  Gurevich, Vsevolod V ^a   Gurevich, Eugenia V ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arrestin; Conformational change; Desensitization; G protein coupled receptors; Structure

Indexed keywords

DIMER; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATE; RETINA S ANTIGEN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONGENITAL MALFORMATION; CRYSTAL STRUCTURE; CYTOPLASM; DIMERIZATION; ENZYME ACTIVATION; HUMAN; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; REVIEW; SENSOR; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION;

ANIMALS; ARRESTIN; HUMANS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 33646414189     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2005.09.008     Document Type: Review

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