-
1
-
-
0024394549
-
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
-
Andersson S, Davis DN, Dahlbäck H, Jörnvall H and Russel DW. (1989) Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem 264:8222-8229.
-
(1989)
J Biol Chem
, vol.264
, pp. 8222-8229
-
-
Andersson, S.1
Davis, D.N.2
Dahlbäck, H.3
Jörnvall, H.4
Russel, D.W.5
-
2
-
-
0030736417
-
A β-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
-
Barak LS, Ferguson SS, Zhang J and Caron MG (1997) A β-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. J Biol Chem 272:27497-274500.
-
(1997)
J Biol Chem
, vol.272
, pp. 27497-274500
-
-
Barak, L.S.1
Ferguson, S.S.2
Zhang, J.3
Caron, M.G.4
-
3
-
-
0023515309
-
Functional desensitization of the isolated β-adrenergic receptor by the beta-adrenergic receptor kinase: Potential role of an analog of the retinal protein arrestin (48-kDa protein)
-
Benovic JL, Kühn H, Weyand I, Codina J, Caron MG and Lefkowitz RJ (1987) Functional desensitization of the isolated β-adrenergic receptor by the beta-adrenergic receptor kinase: Potential role of an analog of the retinal protein arrestin (48-kDa protein). Proc Natl Acad Sci USA 84:8879-8882.
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, pp. 8879-8882
-
-
Benovic, J.L.1
Kühn, H.2
Weyand, I.3
Codina, J.4
Caron, M.G.5
Lefkowitz, R.J.6
-
4
-
-
0030987069
-
How receptors talk to trimeric G proteins
-
Bourne HR (1997) How receptors talk to trimeric G proteins. Curr Opin Cell Biol 9:134-42.
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 134-142
-
-
Bourne, H.R.1
-
5
-
-
0026575003
-
Discrete amino acid sequences of the α1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis
-
Cotecchia S, Ostrowski J, Kjelsberg MA, Caron MG and Lefkowitz RJ (1992) Discrete amino acid sequences of the α1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis. J Biol Chem 267:1633-1639.
-
(1992)
J Biol Chem
, vol.267
, pp. 1633-1639
-
-
Cotecchia, S.1
Ostrowski, J.2
Kjelsberg, M.A.3
Caron, M.G.4
Lefkowitz, R.J.5
-
6
-
-
0001563379
-
Molecular cloning and expression of the cDNA for the hamster α1-adrenergic receptor
-
Cotecchia S, Schwinn DA, Randall RR, Lefkowitz RJ, Caron MG and Kobilka BK (1988) Molecular cloning and expression of the cDNA for the hamster α1-adrenergic receptor. Proc Natl Acad Sci USA 85:7159-7163.
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 7159-7163
-
-
Cotecchia, S.1
Schwinn, D.A.2
Randall, R.R.3
Lefkowitz, R.J.4
Caron, M.G.5
Kobilka, B.K.6
-
7
-
-
0020084268
-
Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes
-
DeLean A, Hancock AA and Lefkowitz RJ (1982) Validation and statistical analysis of a computer modeling method for quantitative analysis of radioligand binding data for mixtures of pharmacological receptor subtypes. Mol Pharmacol 21:5-16.
-
(1982)
Mol Pharmacol
, vol.21
, pp. 5-16
-
-
DeLean, A.1
Hancock, A.A.2
Lefkowitz, R.J.3
-
8
-
-
0026340964
-
Receptor class desensitization of leukocyte chemoattractant receptors
-
Didsbury JR, Uhing RJ, Tomhave E, Gerard C, Gerard N and Snyderman R (1991) Receptor class desensitization of leukocyte chemoattractant receptors. Proc Natl Acad Sci USA 88:11564-11568.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11564-11568
-
-
Didsbury, J.R.1
Uhing, R.J.2
Tomhave, E.3
Gerard, C.4
Gerard, N.5
Snyderman, R.6
-
9
-
-
0030699386
-
Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the α1B-adrenergic receptor
-
Diviani D, Lattion AL and Cotecchia S (1997) Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the α1B-adrenergic receptor. J Biol Chem 272:28712-28719.
-
(1997)
J Biol Chem
, vol.272
, pp. 28712-28719
-
-
Diviani, D.1
Lattion, A.L.2
Cotecchia, S.3
-
10
-
-
0029976109
-
Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the α1B-adrenergic receptor
-
Diviani D, Lattion AL, Larbi N, Kunapuli P, Pronin A, Benovic JL and Cotecchia S (1996) Effect of different G protein-coupled receptor kinases on phosphorylation and desensitization of the α1B-adrenergic receptor. J Biol Chem 271:5049-5058.
-
(1996)
J Biol Chem
, vol.271
, pp. 5049-5058
-
-
Diviani, D.1
Lattion, A.L.2
Larbi, N.3
Kunapuli, P.4
Pronin, A.5
Benovic, J.L.6
Cotecchia, S.7
-
11
-
-
0028791335
-
Role of phosphorylation in agonist-promoted β2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by βARK1
-
Ferguson SS, Menard L, Barak LS, Koch WJ, Colapietro AM and Caron MG (1995) Role of phosphorylation in agonist-promoted β2-adrenergic receptor sequestration. Rescue of a sequestration-defective mutant receptor by βARK1. J Biol Chem 270:24782-24789.
-
(1995)
J Biol Chem
, vol.270
, pp. 24782-24789
-
-
Ferguson, S.S.1
Menard, L.2
Barak, L.S.3
Koch, W.J.4
Colapietro, A.M.5
Caron, M.G.6
-
12
-
-
0030593035
-
Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
Ferguson SSG, Downey WE, Colapietro AM, Barak LS, Menard L and Caron MG (1996) Role of β-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271:363-366.
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.G.1
Downey, W.E.2
Colapietro, A.M.3
Barak, L.S.4
Menard, L.5
Caron, M.G.6
-
13
-
-
0028988023
-
Agonist regulation of α1B-adrenergic receptor subcellular distribution and function
-
Fonseca MI, Button DC and Brown RD (1995) Agonist regulation of α1B-adrenergic receptor subcellular distribution and function. J Biol Chem 270:8902-8909.
-
(1995)
J Biol Chem
, vol.270
, pp. 8902-8909
-
-
Fonseca, M.I.1
Button, D.C.2
Brown, R.D.3
-
14
-
-
0029770657
-
β-arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor
-
Goodman OB Jr, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH and Benovic JL (1996) β-arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor. Nature (London) 383:447-450.
-
(1996)
Nature (London)
, vol.383
, pp. 447-450
-
-
Goodman O.B., Jr.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
Gagnon, A.W.6
Keen, J.H.7
Benovic, J.L.8
-
15
-
-
0026592357
-
Constitutive activation of the α1B-adrenergic receptor by all amino acid substitutions at a single site
-
Kjelsberg MA, Cotecchia S, Ostrowski J, Caron MG and Lefkowitz RJ (1992) Constitutive activation of the α1B-adrenergic receptor by all amino acid substitutions at a single site. J Biol Chem 267:1430-1433.
-
(1992)
J Biol Chem
, vol.267
, pp. 1430-1433
-
-
Kjelsberg, M.A.1
Cotecchia, S.2
Ostrowski, J.3
Caron, M.G.4
Lefkowitz, R.J.5
-
16
-
-
0030756892
-
Endocytosis and recycling of G protein-coupled receptor (Review)
-
Koenig J A and Edwardson JM (1997) Endocytosis and recycling of G protein-coupled receptor (Review). Trends Pharmacol Sci 18:276-287.
-
(1997)
Trends Pharmacol Sci
, vol.18
, pp. 276-287
-
-
Koenig, J.A.1
Edwardson, J.M.2
-
17
-
-
0028181709
-
A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the β2-adrenergic receptor
-
Kong GH, Penn R and Benovic JL (1994) A beta-adrenergic receptor kinase dominant negative mutant attenuates desensitization of the β2-adrenergic receptor. J Biol Chem 269:13084-13087.
-
(1994)
J Biol Chem
, vol.269
, pp. 13084-13087
-
-
Kong, G.H.1
Penn, R.2
Benovic, J.L.3
-
18
-
-
0031036520
-
The role of sequestration in G protein-coupled receptor resensitization. Regulation of β2-adrenergic receptor dephosphorylation by vesicular acidification
-
Krueger KM, Daaka Y, Pitcher JA and Lefkowitz RJ (1997) The role of sequestration in G protein-coupled receptor resensitization. Regulation of β2-adrenergic receptor dephosphorylation by vesicular acidification. J Biol Chem 272:5-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 5-8
-
-
Krueger, K.M.1
Daaka, Y.2
Pitcher, J.A.3
Lefkowitz, R.J.4
-
19
-
-
0028059202
-
Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the α1B-adrenergic receptor
-
Lattion AL, Diviani D and Cotecchia S (1994) Truncation of the receptor carboxyl terminus impairs agonist-dependent phosphorylation and desensitization of the α1B-adrenergic receptor. J Biol Chem 269:22887-22893.
-
(1994)
J Biol Chem
, vol.269
, pp. 22887-22893
-
-
Lattion, A.L.1
Diviani, D.2
Cotecchia, S.3
-
20
-
-
0029822338
-
A constitutively active mutant of the α1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins Gqa and G11α than the wild-type receptor
-
Lee TW, Wise A, Cotecchia S and Milligan G (1996) A constitutively active mutant of the α1B-adrenergic receptor can cause greater agonist-dependent down-regulation of the G-proteins Gqa and G11α than the wild-type receptor. Biochem J 320:79-86.
-
(1996)
Biochem J
, vol.320
, pp. 79-86
-
-
Lee, T.W.1
Wise, A.2
Cotecchia, S.3
Milligan, G.4
-
21
-
-
0031037632
-
The role of the aspartate-arginine-tyrosine triad in the ml muscarinic receptor-mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling
-
Lu ZL, Curtis CA, Jones PG, Pavia J and Hulme EC (1997) The role of the aspartate-arginine-tyrosine triad in the ml muscarinic receptor-mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling. Mol Pharmacol 51:234-241.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 234-241
-
-
Lu, Z.L.1
Curtis, C.A.2
Jones, P.G.3
Pavia, J.4
Hulme, E.C.5
-
22
-
-
0030609874
-
Synergistic regulation of β2-adrenergic receptor sequestration: Intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization
-
Menard L, Ferguson SS, Zhang J, Lin FT, Lefkowitz RJ, Caron MG and Barak LS (1997) Synergistic regulation of β2-adrenergic receptor sequestration: Intracellular complement of β-adrenergic receptor kinase and β-arrestin determine kinetics of internalization. Mol Pharmacol 51:800-808.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 800-808
-
-
Menard, L.1
Ferguson, S.S.2
Zhang, J.3
Lin, F.T.4
Lefkowitz, R.J.5
Caron, M.G.6
Barak, L.S.7
-
23
-
-
0028270707
-
Overlapping multi-site domains of the muscarinic cholinergic hm1 receptor involved in signal transduction and sequestration
-
Moro O, Shockley MS, Lameh J and Sadee W (1994) Overlapping multi-site domains of the muscarinic cholinergic hm1 receptor involved in signal transduction and sequestration. J Biol Chem 269:6651-6655.
-
(1994)
J Biol Chem
, vol.269
, pp. 6651-6655
-
-
Moro, O.1
Shockley, M.S.2
Lameh, J.3
Sadee, W.4
-
24
-
-
0025820391
-
Mechanism of rhodopsin kinase activation
-
Palczewski K, Buczylko J, Kaplan MW, Polans AS and Crabb JW (1991) Mechanism of rhodopsin kinase activation. J Biol Chem 266:12949-12955.
-
(1991)
J Biol Chem
, vol.266
, pp. 12949-12955
-
-
Palczewski, K.1
Buczylko, J.2
Kaplan, M.W.3
Polans, A.S.4
Crabb, J.W.5
-
25
-
-
0028331771
-
A constitutively active mutant β2-adrenergic receptor is constitutively desensitized and phosphorylated
-
Pei G, Samama P, Lohse M, Wang M, Codina J and Lefkowitz RJ (1994) A constitutively active mutant β2-adrenergic receptor is constitutively desensitized and phosphorylated. Proc Natl Acad Sci USA 91:2699-2702.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2699-2702
-
-
Pei, G.1
Samama, P.2
Lohse, M.3
Wang, M.4
Codina, J.5
Lefkowitz, R.J.6
-
26
-
-
0030049488
-
Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor
-
Perez DM, Hwa J, Gaivin R, Mathur M, Brown F and Graham RM (1996) Constitutive activation of a single effector pathway: Evidence for multiple activation states of a G protein-coupled receptor. Mol Pharmacol 49:112-122.
-
(1996)
Mol Pharmacol
, vol.49
, pp. 112-122
-
-
Perez, D.M.1
Hwa, J.2
Gaivin, R.3
Mathur, M.4
Brown, F.5
Graham, R.M.6
-
27
-
-
0028986859
-
Sequestration and recycling of β2-adrenergic receptors permit receptor resensitization
-
Pippig S, Andexinger S and Lohse MJ (1995) Sequestration and recycling of β2-adrenergic receptors permit receptor resensitization. Mol Pharmacol 47:666-676.
-
(1995)
Mol Pharmacol
, vol.47
, pp. 666-676
-
-
Pippig, S.1
Andexinger, S.2
Lohse, M.J.3
-
28
-
-
0028920668
-
Protein kinases 3: Protein kinases that phosphorylate activated G protein coupled receptors
-
Premont RT, Inglese J and Lefkowitz RJ (1995) Protein kinases 3: Protein kinases that phosphorylate activated G protein coupled receptors. FASEB J 9:175-182.
-
(1995)
FASEB J
, vol.9
, pp. 175-182
-
-
Premont, R.T.1
Inglese, J.2
Lefkowitz, R.J.3
-
29
-
-
0027296623
-
Constitutively active mutants of the α2-adrenergic receptor
-
Erratum, J Biol Chem (1994) 269:1566
-
Ren Q, Kurose H, Lefkowitz RJ and Cotecchia S (1993) Constitutively active mutants of the α2-adrenergic receptor. J Biol Chem 268:16483-16387. [Erratum, J Biol Chem (1994) 269:1566].
-
(1993)
J Biol Chem
, vol.268
, pp. 16483-116387
-
-
Ren, Q.1
Kurose, H.2
Lefkowitz, R.J.3
Cotecchia, S.4
-
30
-
-
0029117895
-
Constitutive activation of opsin: Interaction of mutants with rhodopsin kinase and arrestin
-
Rim J and Oprian DD (1995) Constitutive activation of opsin: Interaction of mutants with rhodopsin kinase and arrestin. Biochemistry 34:11938-11945.
-
(1995)
Biochemistry
, vol.34
, pp. 11938-11945
-
-
Rim, J.1
Oprian, D.D.2
-
31
-
-
0026548156
-
In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors
-
Savarese TM and Fraser CM (1992) In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors. Biochem J 283:1-19.
-
(1992)
Biochem J
, vol.283
, pp. 1-19
-
-
Savarese, T.M.1
Fraser, C.M.2
-
32
-
-
0031029841
-
Constitutively active G protein-coupled receptors -potential mechanisms of receptor activation
-
Scheer A and Cotecchia S (1997) Constitutively active G protein-coupled receptors -potential mechanisms of receptor activation. J Recept Signal Transduct Res 17: 57-73.
-
(1997)
J Recept Signal Transduct Res
, vol.17
, pp. 57-73
-
-
Scheer, A.1
Cotecchia, S.2
-
33
-
-
0029897495
-
Constitutively active mutants of the α1-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation
-
Scheer A, Fanelli F, Costa T, De Benedetti PG and Cotecchia S (1996) Constitutively active mutants of the α1-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation. EMBO J 15:3566-3578.
-
(1996)
EMBO J
, vol.15
, pp. 3566-3578
-
-
Scheer, A.1
Fanelli, F.2
Costa, T.3
De Benedetti, P.G.4
Cotecchia, S.5
-
34
-
-
0030614337
-
The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate
-
Scheer A, Fanelli F, Costa T, De Benedetti PG and Cotecchia S (1997) The activation process of the α1B-adrenergic receptor: Potential role of protonation and hydrophobicity of a highly conserved aspartate. Proc Natl Acad Sci USA 94:808-813.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 808-813
-
-
Scheer, A.1
Fanelli, F.2
Costa, T.3
De Benedetti, P.G.4
Cotecchia, S.5
-
35
-
-
0028900858
-
Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt
-
Shi W, Osawa S, Dickerson CD and Weiss ER (1995) Rhodopsin mutants discriminate sites important for the activation of rhodopsin kinase and Gt. J Biol Chem 270:2112-2119.
-
(1995)
J Biol Chem
, vol.270
, pp. 2112-2119
-
-
Shi, W.1
Osawa, S.2
Dickerson, C.D.3
Weiss, E.R.4
-
36
-
-
0031055598
-
Structure and function in rhodopsin - Peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase
-
Thurmond RL, Creuzenet C, Reeves PJ and Khorana HG (1997) Structure and function in rhodopsin - peptide sequences in the cytoplasmic loops of rhodopsin are intimately involved in interaction with rhodopsin kinase. Proc Natl Acad Sci USA 94:1715-1720.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1715-1720
-
-
Thurmond, R.L.1
Creuzenet, C.2
Reeves, P.J.3
Khorana, H.G.4
-
37
-
-
0028568644
-
Sequestration of muscarinic acetylcholine receptor m2 subtypes - Facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2
-
Tsuga H, Kameyama K, Haga T, Kurose H and Nagao T (1994) Sequestration of muscarinic acetylcholine receptor m2 subtypes - facilitation by G protein-coupled receptor kinase (GRK2) and attenuation by a dominant-negative mutant of GRK2. J Biol Chem 269:32522-32527.
-
(1994)
J Biol Chem
, vol.269
, pp. 32522-32527
-
-
Tsuga, H.1
Kameyama, K.2
Haga, T.3
Kurose, H.4
Nagao, T.5
-
38
-
-
0000025689
-
Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments
-
Wilden U, Hall SW and Kuhn H (1986) Phosphodiesterase activation by photoexcited rhodopsin is quenched when rhodopsin is phosphorylated and binds the intrinsic 48-kDa protein of rod outer segments. Proc Natl Acad Sci USA 83:1174-1178.
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 1174-1178
-
-
Wilden, U.1
Hall, S.W.2
Kuhn, H.3
|