Crystal structure of β-arrestin at 1.9 Å: Possible mechanism of receptor binding and membrane translocation

Structure

Volumn 9, Issue 9, 2001, Pages 869-880

  Han, May ^a   Gurevich, Vsevolod V ^b   Vishnivetskiy, Sergey A ^b   Sigler, Paul B ^a,c   Schubert, Carsten ^a,c  

^a YALE UNIVERSITY   (United States)

^b SUN HEALTH RESEARCH INSTITUTE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Arrestin; GPCR; Membrane proteins; Signal transduction; X ray crystallography

Indexed keywords

ADAPTOR PROTEIN; BETA ARRESTIN; CATION; RECEPTOR SUBTYPE; RETINA S ANTIGEN;

ARTICLE; BINDING SITE; CATTLE; CHEMICAL MUTAGENESIS; CHIMERA; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DATA ANALYSIS; DNA HELIX; MEMBRANE TRANSPORT; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR AFFINITY; RECEPTOR BINDING; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; ARRESTINS; BINDING SITES; BIOLOGICAL TRANSPORT; CATTLE; CELL MEMBRANE; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HETEROTRIMERIC GTP-BINDING PROTEINS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

BOS TAURUS; BOVINAE;

EID: 0034802172     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(01)00644-X     Document Type: Article

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