Structure and function of the third intracellular loop of the 5- hydroxytryptamine(2A) receptor: The third intracellular loop is α-helical and binds purified arrestins

Journal of Neurochemistry

Volumn 72, Issue 5, 1999, Pages 2206-2214

  Gelber, Edward I ^a   Kroeze, Wesley K ^a   Willins, David L ^a   Gray, John A ^a   Sinar, Christine A ^a   Hyde, Edward G ^a   Gurevich, Vsevolod ^b   Benovic, Jeffrey ^c   Roth, Bryan L ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SUN HEALTH RESEARCH INSTITUTE   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Arrestin; 5 HT(2A) receptor; Receptor effector coupling; Structure function

Indexed keywords

GLUTATHIONE TRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; MONOCLONAL ANTIBODY; RETINA S ANTIGEN; SEROTONIN; SEROTONIN 2A RECEPTOR; SYNTHETIC PEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN CORTEX; CIRCULAR DICHROISM; CONTROLLED STUDY; IMMUNOFLUORESCENCE MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; PYRAMIDAL NERVE CELL; RAT; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ARRESTINS; FLUORESCENT ANTIBODY TECHNIQUE; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; PREFRONTAL CORTEX; PROTEIN STRUCTURE, SECONDARY; PYRAMIDAL CELLS; RATS; RECEPTORS, SEROTONIN; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

ANIMALIA;

EID: 0032971464     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1999.0722206.x     Document Type: Article

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