Differential desensitization, receptor phosphorylation, β-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7

Journal of Biological Chemistry

Volumn 279, Issue 22, 2004, Pages 23214-23222

  Kohout, Trudy A ^a   Nicholas, Shelby L ^a   Perry, Stephen J ^a   Reinhart, Greg ^a   Junger, Sachiko ^a   Struthers, R Scott ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CALCIUM; CELLS; ENZYMES; GENETIC ENGINEERING; REDOX REACTIONS;

CHEMOKINE RECEPTORS; DESENSITIZATION;

BIOCHEMISTRY;

ALANINE; BETA ARRESTIN; CHEMOKINE RECEPTOR CCR7; G PROTEIN COUPLED RECEPTOR; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN; PROTEIN CCL19; PROTEIN CCL21; PROTEIN KINASE C; SERINE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM MOBILIZATION; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CLUSTER ANALYSIS; CONTROLLED STUDY; DESENSITIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; T CELL LYMPHOMA;

ARRESTINS; CELL LINE, TUMOR; CHEMOKINES, CC; HUMANS; LIGANDS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; RECEPTORS, CHEMOKINE; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 2542423686     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M402125200     Document Type: Article

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