The Adaptor Protein β-Arrestin2 Enhances Endocytosis of the Low Density Lipoprotein Receptor

Journal of Biological Chemistry

Volumn 278, Issue 45, 2003, Pages 44238-44245

  Wu, Jiao Hui ^e   Peppel, Karsten ^e   Nelson, Christopher D ^e   Lin, Fang Tsyr ^a   Kohout, Trudy A ^b   Miller, William E ^c   Exum, Sabrina T ^e   Freedman, Neil J ^d  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b NEUROCRINE BIOSCIENCES INC   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; FLUORESCENCE; METABOLISM; MUTAGENESIS; PRECIPITATION (CHEMICAL); RNA;

ENDOCYTOSIS;

PROTEINS;

ADAPTOR PROTEIN; ALANINE; ASPARTIC ACID; BETA ARRESTIN; BETA ARRESTIN 1; BETA ARRESTIN 2; FLUORESCENT DYE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HYBRID PROTEIN; INTERMEDIATE DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; SERINE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOPLASM; EMBRYO; ENDOCYTOSIS; FIBROBLAST; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HOMOZYGOSITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; KNOCKOUT MOUSE; LIPID DIET; LIPID TRANSPORT; LIPOPROTEIN METABOLISM; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; RAT; RECEPTOR AFFINITY; RNA ANALYSIS; RNA INTERFERENCE; STOICHIOMETRY; WILD TYPE;

ANIMALS; ARRESTINS; CELL LINE; CHO CELLS; CHOLESTEROL; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CLONING, MOLECULAR; CRICETINAE; DIETARY FATS; EMBRYO; ENDOCYTOSIS; FIBROBLASTS; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; HUMANS; IMMUNOSORBENT TECHNIQUES; KIDNEY; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTAGENESIS; RECEPTORS, LDL; RECOMBINANT FUSION PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0242414728     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309450200     Document Type: Article

References (46)

1. Brown, M. S., and Goldstein, J. L. (1986) Science 232, 34-47
2. Kesaniemi, Y. A., Witztum, J. L., and Steinbrecher, U. P. (1983) J. Clin. Invest. 71, 950-959
3. Davis, C. G., van Driel, I. R., Russell, D. W., Brown, M. S., and Goldstein, J. L. (1987) J. Biol. Chem. 262, 4075-4082
4. Chen, W. J., Goldstein, J. L., and Brown, M. S. (1990) J. Biol. Chem. 265, 3116-3123
5. Kibbey, R. G., Rizo, J., Gierasch, L. M., and Anderson, R. G. (1998) J. Cell Biol. 142, 59-67
6. He, G., Gupta, S., Yi, M., Michaely, P., Hobbs, H. H., and Cohen, J. C. (2002) J. Biol. Chem. 277, 44044-44049
7. Garcia, C. K., Wilund, K., Arca, M., Zuliani, G., Fellin, R., Maioli, M., Calandra, S., Bertolini, S., Cossu, F., Grishin, N., Barnes, R., Cohen, J. C., and Hobbs, H. H. (2001) Science 292, 1394-1398
8. Attramadal, H., Arriza, J., Aoki, C., Dawson, T., Codina, J., Kwatra, M. M., Snyder, S., Caron, M., and Lefkowitz, R. (1992) J. Biol. Chem. 267, 17882-17890
9. Krupnick, J. G., Santini, F., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1997) J. Biol. Chem. 272, 32507-32512
10. Gurevich, V. V., Dion, S. B., Onorato, J. J., Ptasienski, J., Kim, C. M., Sterne-Marr, R., Hosey, M. M., and Benovic, J. L. (1995) J. Biol. Chem. 270, 720-731
11. Miller, W. E., and Lefkowitz, R. J. (2001) Curr. Opin. Cell Biol. 13, 139-145
12. Goodman, O. B., Jr., Krupnick, J. G., Santini, F., Gurevich, V. V., Penn, R. B., Gagnon, A. W., Keen, J. H., and Benovic, J. L. (1996) Nature 383, 447-450
13. Laporte, S. A., Oakley, R. H., Holt, J. A., Barak, L. S., and Caron, M. G. (2000) J. Biol. Chem. 275, 23120-23126
14. Kohout, T. A., Lin, F. S., Perry, S. J., Conner, D. A., and Lefkowitz, R. J. (2001) Proc. Natl. Acad. Sci. U. S. A. 98, 1601-1606
15. von Zastrow, M., and Kobilka, B. K. (1992) J. Biol. Chem. 267, 3530-3538
16. Barak, L. S., Ferguson, S. S., Zhang, J., and Caron, M. G. (1997) J. Biol. Chem. 272, 27497-27500
17. Anderson, R. G., Brown, M. S., Beisiegel, U., and Goldstein, J. L. (1982) J. Cell Biol. 93, 523-531
18. Bohn, L. M., Lefkowitz, R. J., Gainetdinov, R. R., Peppel, K., Caron, M. G., and Lin, F. T. (1999) Science 286, 2495-2498
19. Paigen, B., Morrow, A., Holmes, P., Mitchell, D., and Williams, R. (1987) Atherosclerosis 68, 231-240
20. Knouff, C., Hinsdale, M. E., Mezdour, H., Altenburg, M. K., Watanabe, M., Quarfordt, S. H., Sullivan, P. M., and Maeda, N. (1999) J. Clin. Invest. 103, 1579-1586
21. Yamamoto, T., Davis, C. G., Brown, M. S., Schneider, W. J., Casey, M. L., Goldstein, J. L., and Russell, D. W. (1984) Cell 39, 27-38
22. Freedman, N. J., Ament, A. S., Oppermann, M., Stoffel, R. H., Exum, S. T., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 17734-17743
23. Freedman, N. J., Liggett, S. B., Drachman, D. E., Pei, G., Caron, M. G., and Lefkowitz, R. J. (1995) J. Biol. Chem. 270, 17953-17961
24. Miller, W. E., Maudsley, S., Ahn, S., Khan, K. D., Luttrell, L. M., and Lefkowitz, R. J. (2000) J. Biol. Chem. 275, 11312-11319
25. Kingsley, D. M., and Krieger, M. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 5454-5458
26. Ahn, S., Nelson, C. D., Garrison, T. R., Miller, W. E., and Lefkowitz, R. J. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 1740-1744
27. Goldstein, J. L., Basu, S. K., and Brown, M. S. (1983) Methods Enzymol. 98, 241-260
28. Innerarity, T., Pitas, R., and Mahley, R. (1986) Methods Enzymol. 129, 542-565
29. Chung, B., Segrest, J., Ray, M., Brunqell, J., Hokanson, J., Krauss, R., Beaudrie, K., and Cone, J. (1986) Methods Enzymol. 128, 181-209
30. Haddad, G., Amiri, F., and Garcia, R. (1997) Regul. Pept. 68, 111-117
31. Oppermann, M., Freedman, N. J., Alexander, R. W., and Lefkowitz, R. J. (1996) J. Biol. Chem. 271, 13266-13272
32. Sambrook, J., and Russell, D. W. (2001) Molecular Cloning: A Laboratory Manual, 3rd Ed., Cold Spring Harbor Laboratory Press, Cold Spring Harbor
33. Menard, L., Ferguson, S. S., Zhang, J., Lin, F. T., Lefkowitz, R. J., Caron, M. G., and Barak, L. S. (1997) Mol. Pharmacol. 51, 800-808
34. Krupnick, J. G., Goodman, O. B., Jr., Keen, J. H., and Benovic, J. L. (1997) J. Biol. Chem. 272, 15011-15016
35. Hein, L., Meinel, L., Pratt, R. E., Dzau, V. J., and Kobilka, B. K. (1997) Mol. Endocrinol. 11, 1266-1277
36. Kishimoto, A., Brown, M. S., Slaughter, C. A., and Goldstein, J. L. (1987) J. Biol. Chem. 262, 1344-1351
37. Kishimoto, A., Goldstein, J. L., and Brown, M. S. (1987) J. Biol. Chem. 262, 9367-9373
38. Bansal, A., and Gierasch, L. M. (1991) Cell 67, 1195-1201
39. Oakley, R. H., Laporte, S. A., Holt, J. A., Caron, M. G., and Barak, L. S. (2000) J. Biol. Chem. 275, 17201-17210
40. Laporte, S. A., Oakley, R. H., Zhang, J., Holt, J. A., Ferguson, S. S., Caron, M. G., and Barak, L. S. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 3712-3717
41. Lin, F. T., Krueger, K. M., Kendall, H. E., Daaka, Y., Fredericks, Z. L., Pitcher, J. A., and Lefkowitz, R. J. (1997) J. Biol. Chem. 272, 31051-31057
42. Lin, F. T., Chen, W., Shenoy, S., Cong, M., Exum, S. T., and Lefkowitz, R. J. (2002) Biochemistry 41, 10692-10699
43. Mehta, K. D., Chen, W. J., Goldstein, J. L., and Brown, M. S. (1991) J. Biol. Chem. 266, 10406-10414
44. Yokode, M., Pathak, R. K., Hammer, R. E., Brown, M. S., Goldstein, J. L., and Anderson, R. G. (1992) J. Cell Biol. 117, 39-46
45. Dueland, S., Drisko, J., Graf, L., Machleder, D., Lusis, A. J., and Davis, R. A. (1993) J. Lipid Res. 34, 923-931
46. Rohlmann, A., Gotthardt, M., Hammer, R. E., and Herz, J. (1998) J. Clin. Invest. 101, 689-695