메뉴 건너뛰기




Volumn 56, Issue 4, 1999, Pages 728-736

A dileucine-based motif in the C-terminal tail of the lutropin/choriogonadotropin receptor inhibits endocytosis of the agonist- receptor complex

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN RECEPTOR; DYNAMIN; LEUCINE; LUTEINIZING HORMONE; LUTEINIZING HORMONE RECEPTOR; RETINA S ANTIGEN;

EID: 0032836647     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 0020356604 scopus 로고
    • Internalization and degradation or receptor-bound human choriogonadotropuin in Leydig tumor cells: Fate of the hormone subunits
    • Ascoli M (1982) Internalization and degradation or receptor-bound human choriogonadotropuin in Leydig tumor cells: Fate of the hormone subunits. J Biol Chem 257:13306-13311.
    • (1982) J Biol Chem , vol.257 , pp. 13306-13311
    • Ascoli, M.1
  • 2
    • 0021042341 scopus 로고
    • An improved method for the solubilization of stable gonadotropin receptors
    • Ascoli M (1983) An improved method for the solubilization of stable gonadotropin receptors. Endocrinology 113:2129-2134.
    • (1983) Endocrinology , vol.113 , pp. 2129-2134
    • Ascoli, M.1
  • 3
    • 0021702460 scopus 로고
    • Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin
    • Ascoli M (1984) Lysosomal accumulation of the hormone-receptor complex during receptor-mediated endocytosis of human choriogonadotropin. J Cell Biol 99:1242-1250.
    • (1984) J Cell Biol , vol.99 , pp. 1242-1250
    • Ascoli, M.1
  • 4
    • 0343053231 scopus 로고
    • Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells
    • Ascoli M and Puett D (1978) Gonadotropin binding and stimulation of steroidogenesis in Leydig tumor cells. Proc Natl Acad Sci USA 75:99-102.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 99-102
    • Ascoli, M.1    Puett, D.2
  • 5
    • 0023103487 scopus 로고
    • On the fates of receptor-bound human ovine luteinizing hormone and human choriogonadotropin in cultured Leydig tumor cells: Demonstration of similar rates of internalization
    • Ascoli M and Segaloff DL (1987) On the fates of receptor-bound human ovine luteinizing hormone and human choriogonadotropin in cultured Leydig tumor cells: Demonstration of similar rates of internalization. Endocrinology 120:1161-1172.
    • (1987) Endocrinology , vol.120 , pp. 1161-1172
    • Ascoli, M.1    Segaloff, D.L.2
  • 6
    • 0028036513 scopus 로고
    • Induction of mutant dynamin specifically blocks endocytic coated vesicle formation
    • Damke H, Baba T, Warnock DE and Schmid SL (1994) Induction of mutant dynamin specifically blocks endocytic coated vesicle formation. J Cell Biol 127:915-934.
    • (1994) J Cell Biol , vol.127 , pp. 915-934
    • Damke, H.1    Baba, T.2    Warnock, D.E.3    Schmid, S.L.4
  • 7
    • 0029923845 scopus 로고    scopus 로고
    • Two mutations of the lutropin/ choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis
    • Dhanwada KR, Vijapurkar U and Ascoli M (1996) Two mutations of the lutropin/ choriogonadotropin receptor that impair signal transduction also interfere with receptor-mediated endocytosis. Mol Endocrinol 10:544-554.
    • (1996) Mol Endocrinol , vol.10 , pp. 544-554
    • Dhanwada, K.R.1    Vijapurkar, U.2    Ascoli, M.3
  • 9
    • 0032512441 scopus 로고    scopus 로고
    • Transfected cells express mostly the intracellular precursor of the lutropin/choriogonadotropin receptor but this precursor binds choriogonadotropin with high affinity
    • Fabritz J, Ryan S and Ascoli M (1998) Transfected cells express mostly the intracellular precursor of the lutropin/choriogonadotropin receptor but this precursor binds choriogonadotropin with high affinity. Biochemistry 37:664-672.
    • (1998) Biochemistry , vol.37 , pp. 664-672
    • Fabritz, J.1    Ryan, S.2    Ascoli, M.3
  • 10
    • 0001003295 scopus 로고    scopus 로고
    • Pleiotropic role for GRKs and β-arrestins in receptor regulation
    • Ferguson SSG, Zhang J, Barak LS and Caron MG (1997) Pleiotropic role for GRKs and β-arrestins in receptor regulation. News Physiol Sci 12:145-151.
    • (1997) News Physiol Sci , vol.12 , pp. 145-151
    • Ferguson, S.S.G.1    Zhang, J.2    Barak, L.S.3    Caron, M.G.4
  • 11
    • 0030812586 scopus 로고    scopus 로고
    • A dileucine motif in the C terminus of the ftj-adrenergic receptor is involved in receptor internalization
    • Gabilondo AM, Hegler J, Krasel C, Boivin-Jahns V, Hein L and Lohse MJ (1997) A dileucine motif in the C terminus of the ftj-adrenergic receptor is involved in receptor internalization. Proc Natl Acad Sci USA 94:12285-12290.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12285-12290
    • Gabilondo, A.M.1    Hegler, J.2    Krasel, C.3    Boivin-Jahns, V.4    Hein, L.5    Lohse, M.J.6
  • 13
    • 0026731460 scopus 로고
    • Pathways of internalization of the hCG/LH receptor: Immunoelectron microscopic studies in Leydig cells and transfected L cells
    • Ghinea N, Vuhai MT, Groyer-Picard M-T, Houllier A, Schoëvaërt D and Milgrom E ( 1992) Pathways of internalization of the hCG/LH receptor: Immunoelectron microscopic studies in Leydig cells and transfected L cells. J Cell Biol 118:1347-1358.
    • (1992) J Cell Biol , vol.118 , pp. 1347-1358
    • Ghinea, N.1    Vuhai, M.T.2    Groyer-Picard, M.-T.3    Houllier, A.4    Schoëvaërt, D.5    Milgrom, E.6
  • 14
    • 0032568841 scopus 로고    scopus 로고
    • Di-leucine-mediated internalization of ligand by a truncated growth hormone receptor is independent of the ubiquitin conjugation system
    • Govers R, van Kerkhof P, Schwartz AL and Strous GJ (1998) Di-leucine-mediated internalization of ligand by a truncated growth hormone receptor is independent of the ubiquitin conjugation system. J Biol Chem 273:16426-16433.
    • (1998) J Biol Chem , vol.273 , pp. 16426-16433
    • Govers, R.1    Van Kerkhof, P.2    Schwartz, A.L.3    Strous, G.J.4
  • 16
    • 0025788788 scopus 로고
    • The slow rate of internalization of deglycosylated hCG is not due to its inability to stimulate cAMP accumulation
    • Hoelscher SR, Sairam MR and Ascoli M (1991) The slow rate of internalization of deglycosylated hCG is not due to its inability to stimulate cAMP accumulation. Endocrinology 128:2837-2843.
    • (1991) Endocrinology , vol.128 , pp. 2837-2843
    • Hoelscher, S.R.1    Sairam, M.R.2    Ascoli, M.3
  • 17
    • 0027999333 scopus 로고
    • Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells
    • Kawate N and Menon KMJ ( 1994) Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells. J Biol Chem 269:30651-30658.
    • (1994) J Biol Chem , vol.269 , pp. 30651-30658
    • Kawate, N.1    Menon, K.M.J.2
  • 18
    • 0030794182 scopus 로고    scopus 로고
    • Linking cargo to vesicle formation: Receptor tail interactions with coat proteins
    • Kirchhausen T, Bonifacino JS and Riezman H (1997) Linking cargo to vesicle formation: Receptor tail interactions with coat proteins. Curr Opin Cell Biol 9:488-495.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 488-495
    • Kirchhausen, T.1    Bonifacino, J.S.2    Riezman, H.3
  • 19
    • 0030756892 scopus 로고    scopus 로고
    • Endocytosis and recycling of G protein-coupled receptors
    • Koenig JA and Edwardson JM ( 1997) Endocytosis and recycling of G protein-coupled receptors. Trends Pharmacol Sci 18:276-287.
    • (1997) Trends Pharmacol Sci , vol.18 , pp. 276-287
    • Koenig, J.A.1    Edwardson, J.M.2
  • 20
    • 0031747997 scopus 로고    scopus 로고
    • The role of receptor kinases and arresting in G protein-coupled receptor regulation
    • Krupnick JG and Benovic JL (1998) The role of receptor kinases and arresting in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
    • (1998) Annu Rev Pharmacol Toxicol , vol.38 , pp. 289-319
    • Krupnick, J.G.1    Benovic, J.L.2
  • 21
    • 0030967614 scopus 로고    scopus 로고
    • Arrestin/clathrin interaction: Localization of the clathrin binding domain of nonvisual arrestins to the carboxyl terminus
    • OB
    • Krupnick JG, Goodman J, OB, Keen JH and Benovic JL (1997) Arrestin/clathrin interaction: Localization of the clathrin binding domain of nonvisual arrestins to the carboxyl terminus. J Biol Chem 272:15011-15016.
    • (1997) J Biol Chem , vol.272 , pp. 15011-15016
    • Krupnick, J.G.1    Goodman, J.2    Keen, J.H.3    Benovic, J.L.4
  • 23
    • 0032541044 scopus 로고    scopus 로고
    • Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin (LH/CG) receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization
    • Lazari MFM, Bertrand JE, Nakamura K, Liu X, Krupnick JG, Benovic JL and Ascoli M (1998) Mutation of individual serine residues in the C-terminal tail of the lutropin/choriogonadotropin (LH/CG) receptor reveal distinct structural requirements for agonist-induced uncoupling and agonist-induced internalization. J Biol Chem 273:18316-18324.
    • (1998) J Biol Chem , vol.273 , pp. 18316-18324
    • Lazari, M.F.M.1    Bertrand, J.E.2    Nakamura, K.3    Liu, X.4    Krupnick, J.G.5    Benovic, J.L.6    Ascoli, M.7
  • 24
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors, III, new roles for receptor kinases and β-arrestins in receptor signaling and desensitization
    • Lefkowitz RJ (1998) G protein-coupled receptors, III, New roles for receptor kinases and β-arrestins in receptor signaling and desensitization. J Biol Chem 273:18677-18680.
    • (1998) J Biol Chem , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 25
    • 0020625309 scopus 로고
    • On the mechanisms involved in the regulation of the cell surface receptors for human choriogonadotropin and mouse epidermal growth factor in cultured leydig tumor cells
    • Lloyd CE and Ascoli M ( 1983 ) On the mechanisms involved in the regulation of the cell surface receptors for human choriogonadotropin and mouse epidermal growth factor in cultured Leydig tumor cells. J Cell Biol 96:521-526.
    • (1983) J Cell Biol , vol.96 , pp. 521-526
    • Lloyd, C.E.1    Ascoli, M.2
  • 27
    • 0032567352 scopus 로고    scopus 로고
    • Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/ choriogonadotropin receptor
    • Min K-S, Liu X, Fabritz J, Jaquette J, Abell AN and Ascoli M (1998) Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/ choriogonadotropin receptor. J Biol Chem 273:34911-34919.
    • (1998) J Biol Chem , vol.273 , pp. 34911-34919
    • Min, K.-S.1    Liu, X.2    Fabritz, J.3    Jaquette, J.4    Abell, A.N.5    Ascoli, M.6
  • 29
    • 0033520424 scopus 로고    scopus 로고
    • The rate of internalization of the gonadotropin receptors is greatly affected by the origin of extracellular domain
    • in press
    • Nakamura K, Liu X and Ascoli M (1999) The rate of internalization of the gonadotropin receptors is greatly affected by the origin of extracellular domain. J Biol Chem, in press.
    • (1999) J Biol Chem
    • Nakamura, K.1    Liu, X.2    Ascoli, M.3
  • 31
    • 0032522517 scopus 로고    scopus 로고
    • Dileucinebased sorting signals bind to the β-chain of AP-I at a site distinct and regulated differently from the tyrosine-based motif binding site
    • Rapoport I, Chen Y-C, Cupers P, Shoelson SE and Kirchhausen T (1998) Dileucinebased sorting signals bind to the β-chain of AP-I at a site distinct and regulated differently from the tyrosine-based motif binding site. EMBO J 17:2148-2155.
    • (1998) EMBO J , vol.17 , pp. 2148-2155
    • Rapoport, I.1    Chen, Y.-C.2    Cupers, P.3    Shoelson, S.E.4    Kirchhausen, T.5
  • 32
    • 0026591515 scopus 로고
    • Effects of truncations of the cytoplasmic tail of the lutropin/choriogonadotropin receptor on receptor-mediated hormone internalization
    • Rodríguez MC, Xie Y-B, Wang H, Collison K and Segaloff DL (1992) Effects of truncations of the cytoplasmic tail of the lutropin/choriogonadotropin receptor on receptor-mediated hormone internalization. Mol Endocrinol 6:327-336.
    • (1992) Mol Endocrinol , vol.6 , pp. 327-336
    • Rodríguez, M.C.1    Xie, Y.-B.2    Wang, H.3    Collison, K.4    Segaloff, D.L.5
  • 33
    • 0028842897 scopus 로고
    • Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not the lutropin/choriogonadotropin receptor
    • Rozell TG, Wang H, Liu X and Segaloff DL (1995) Intracellular retention of mutant gonadotropin receptors results in loss of hormone binding activity of the follitropin receptor but not the lutropin/choriogonadotropin receptor. Mol Endocrinol 9:1727-1736.
    • (1995) Mol Endocrinol , vol.9 , pp. 1727-1736
    • Rozell, T.G.1    Wang, H.2    Liu, X.3    Segaloff, D.L.4
  • 35
    • 0027158153 scopus 로고
    • The lutropin/choriogonadotropin (LH/CG) receptor. . . 4 years later
    • Segaloff DL and Ascoli M (1993) The lutropin/choriogonadotropin (LH/CG) receptor. . . 4 years later. Endocr Rev 14:324-347.
    • (1993) Endocr Rev , vol.14 , pp. 324-347
    • Segaloff, D.L.1    Ascoli, M.2
  • 36
    • 0030989801 scopus 로고    scopus 로고
    • Identification of cytoplasmic motifs required for short prolactin receptor internalization
    • Vincent V, Goffm V, Rozakis-Adcock M, Mornon J-P and Kelly PA (1997) Identification of cytoplasmic motifs required for short prolactin receptor internalization. J Biol Chem 272:7062-7068.
    • (1997) J Biol Chem , vol.272 , pp. 7062-7068
    • Vincent, V.1    Goffm, V.2    Rozakis-Adcock, M.3    Mornon, J.-P.4    Kelly, P.A.5
  • 37
    • 0029889283 scopus 로고    scopus 로고
    • Progressive cytoplasmic tail truncations of the lutropin-choriogonadotropin receptor prevent agonist- or phorbol esterinduced phosphorylation. Impair agonist-or phorbol ester-induced desensitization and enhance agonist-induced receptor down-regulation
    • Wang Z, Hipkin RW and Ascoli M ( 1996) Progressive cytoplasmic tail truncations of the lutropin-choriogonadotropin receptor prevent agonist- or phorbol esterinduced phosphorylation. impair agonist-or phorbol ester-induced desensitization and enhance agonist-induced receptor down-regulation. Mol Endocrinol 10:748-759.
    • (1996) Mol Endocrinol , vol.10 , pp. 748-759
    • Wang, Z.1    Hipkin, R.W.2    Ascoli, M.3
  • 38
    • 0031019920 scopus 로고    scopus 로고
    • Phosphorylation of the lutropin/choriogonadotropin receptor facilitates uncoupling of the receptor from adenylyl cyclase and endocytosis of the bound hormone
    • Wang Z, Liu X and Ascoli M (1997) Phosphorylation of the lutropin/choriogonadotropin receptor facilitates uncoupling of the receptor from adenylyl cyclase and endocytosis of the bound hormone. Mol Endocrinol 11:183-192.
    • (1997) Mol Endocrinol , vol.11 , pp. 183-192
    • Wang, Z.1    Liu, X.2    Ascoli, M.3
  • 39
    • 0027457240 scopus 로고
    • Mutation of a highly conserved acidic residue present in the second intracellular loop of G protein-coupled receptors does not impair hormone binding or signal transduction of the LH/CG receptor
    • Wang Z, Wang H and Ascoli M (1993) Mutation of a highly conserved acidic residue present in the second intracellular loop of G protein-coupled receptors does not impair hormone binding or signal transduction of the LH/CG receptor. Mol Endocrinol 7:85-93.
    • (1993) Mol Endocrinol , vol.7 , pp. 85-93
    • Wang, Z.1    Wang, H.2    Ascoli, M.3
  • 40
    • 0019404817 scopus 로고
    • A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands
    • Wiley HS and Cunningham DD (1981) A steady state model for analyzing the cellular binding, internalization and degradation of polypeptide ligands. Cell 25: 433-440.
    • (1981) Cell , vol.25 , pp. 433-440
    • Wiley, H.S.1    Cunningham, D.D.2
  • 41
    • 0019945866 scopus 로고
    • The endocytotic rate constant: A cellular parameter for quantitating receptor-mediated endocytosis
    • Wiley HS and Cunningham DD (1982) The endocytotic rate constant: A cellular parameter for quantitating receptor-mediated endocytosis. J Biol Chem 257:4222-4229.
    • (1982) J Biol Chem , vol.257 , pp. 4222-4229
    • Wiley, H.S.1    Cunningham, D.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.