-
1
-
-
33745682818
-
Acute liver failure
-
Wright, R., Alberti, K. G. M. M., Karran, S. and Millward-Sadler, G. H., eds., W. B. Saunders Company Ltd, London
-
Saunders, S. J., Seggie, J., Kirsch, R. E. and Terblanche, J. (1997) Acute liver failure. In Liver and Biliary Disease, Pathophysiology, Diagnosis and Management (Wright, R., Alberti, K. G. M. M., Karran, S. and Millward-Sadler, G. H., eds.), pp. 569-584, W. B. Saunders Company Ltd, London
-
(1997)
Liver and Biliary Disease, Pathophysiology, Diagnosis and Management
, pp. 569-584
-
-
Saunders, S.J.1
Seggie, J.2
Kirsch, R.E.3
Terblanche, J.4
-
3
-
-
0036163759
-
Mechanisms of hepatotoxicity
-
Jaeschke, H., Gores, G. J., Cederbaum, A. I., Hinson, J. A., Pessayre, D. and Lemasters, J. J. (2002) Mechanisms of hepatotoxicity. Toxicol. Sci. 65, 166-176
-
(2002)
Toxicol. Sci.
, vol.65
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
Hinson, J.A.4
Pessayre, D.5
Lemasters, J.J.6
-
4
-
-
0032897568
-
V. Necrapoptosis and the mitochondrial permeability transition: Shared pathways to necrosis and apoptosis
-
Lemasters, J. J. (1999) V. Necrapoptosis and the mitochondrial permeability transition: shared pathways to necrosis and apoptosis. Am. J. Physiol. 276, G1-G6
-
(1999)
Am. J. Physiol.
, vol.276
-
-
Lemasters, J.J.1
-
5
-
-
0034320568
-
Mechanisms of apoptosis
-
Reed, J. C. (2000) Mechanisms of apoptosis. Am. J. Pathol. 157, 1415-1430
-
(2000)
Am. J. Pathol.
, vol.157
, pp. 1415-1430
-
-
Reed, J.C.1
-
6
-
-
0031870774
-
Apoptosis: Molecular aspects of cell death and disease
-
Granville, D. J., Carthy, C. M., Hunt, D. W. and McManus, B. M. (1998) Apoptosis: Molecular aspects of cell death and disease. Lab. Invest. 78, 893-913
-
(1998)
Lab. Invest.
, vol.78
, pp. 893-913
-
-
Granville, D.J.1
Carthy, C.M.2
Hunt, D.W.3
McManus, B.M.4
-
7
-
-
17344387813
-
Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis
-
Strand, S., Hofmann, W. J., Grambihler, A. et al. (1998) Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis. Nat. Med. 4, 588-593
-
(1998)
Nat. Med.
, vol.4
, pp. 588-593
-
-
Strand, S.1
Hofmann, W.J.2
Grambihler, A.3
-
8
-
-
0034261520
-
Apoptosis in acute hepatic failure: Histopathological study of human liver tissue using the tunel method and immunohistochemistry
-
Kasahara, I., Saitoh, K. and Nakamura, K. (2000) Apoptosis in acute hepatic failure: histopathological study of human liver tissue using the tunel method and immunohistochemistry. J. Med. Dent. Sci. 47, 167-175
-
(2000)
J. Med. Dent. Sci.
, vol.47
, pp. 167-175
-
-
Kasahara, I.1
Saitoh, K.2
Nakamura, K.3
-
9
-
-
10744225137
-
Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-κB activation
-
Schoemaker, M. H., Gommans, W. M., Conde de la Rosa, L. et al. (2003) Resistance of rat hepatocytes against bile acid-induced apoptosis in cholestatic liver injury is due to nuclear factor-κB activation. J. Hepatol. 39, 153-161
-
(2003)
J. Hepatol.
, vol.39
, pp. 153-161
-
-
Schoemaker, M.H.1
Gommans, W.M.2
Conde De La Rosa, L.3
-
10
-
-
2342575851
-
Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury
-
Fickert, P., Trauner, M., Fuchsbichler, A., Zollner, G. and Wagner, M. (2003) Inhibition of poly(ADP-ribose) polymerase (PARP) protects mice from cholestatic liver injury. Hepatology 38 (suppl. 1), 576A
-
(2003)
Hepatology
, vol.38
, Issue.1 SUPPL.
-
-
Fickert, P.1
Trauner, M.2
Fuchsbichler, A.3
Zollner, G.4
Wagner, M.5
-
11
-
-
2342615751
-
Apoptosis and oncotic necrosis during acute liver injury after bile duct ligation in mice
-
Gujral, J. and Jaeschke, H. (2003) Apoptosis and oncotic necrosis during acute liver injury after bile duct ligation in mice. Hepatology 38 (suppl. 1), 240A
-
(2003)
Hepatology
, vol.38
, Issue.1 SUPPL.
-
-
Gujral, J.1
Jaeschke, H.2
-
12
-
-
0036708291
-
Death receptor-mediated apoptosis and the liver
-
Yoon, J. H. and Gores, G. J. (2002) Death receptor-mediated apoptosis and the liver. J. Hepatol. 37, 400-410
-
(2002)
J. Hepatol.
, vol.37
, pp. 400-410
-
-
Yoon, J.H.1
Gores, G.J.2
-
13
-
-
0032882798
-
Inflammation-induced cholestasis
-
Trauner, M., Fickert, P. and Stauber, R. E. (1999) Inflammation-induced cholestasis. J. Gastroenterol. Hepatol. 14, 946-959
-
(1999)
J. Gastroenterol. Hepatol.
, vol.14
, pp. 946-959
-
-
Trauner, M.1
Fickert, P.2
Stauber, R.E.3
-
14
-
-
12244250729
-
Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer
-
Bortolami, M., Venturi, C., Giacomelli, L. et al. (2002) Cytokine, infiltrating macrophage and T cell-mediated response to development of primary and secondary human liver cancer. Dig. Liver Dis. 34, 794-801
-
(2002)
Dig. Liver Dis.
, vol.34
, pp. 794-801
-
-
Bortolami, M.1
Venturi, C.2
Giacomelli, L.3
-
15
-
-
0036186666
-
Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas
-
Beyaert, R., van Loo, G., Heyninck, K. and Vandenabeele, P. (2002) Signaling to gene activation and cell death by tumor necrosis factor receptors and Fas. Int. Rev. Cytol. 214, 225-272
-
(2002)
Int. Rev. Cytol.
, vol.214
, pp. 225-272
-
-
Beyaert, R.1
Van Loo, G.2
Heyninck, K.3
Vandenabeele, P.4
-
16
-
-
0037815277
-
Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis
-
Harper, N., Hughes, M., MacFarlane, M. and Cohen, G. M. (2003) Fas-associated death domain protein and caspase-8 are not recruited to the tumor necrosis factor receptor 1 signaling complex during tumor necrosis factor-induced apoptosis. J. Biol. Chem. 278, 25534-25541
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 25534-25541
-
-
Harper, N.1
Hughes, M.2
MacFarlane, M.3
Cohen, G.M.4
-
17
-
-
0033082268
-
Proteases to die for
-
Cryns, V. and Yuan, Y. (1999) Proteases to die for. Genes. Dev. 13, 371
-
(1999)
Genes. Dev.
, vol.13
, pp. 371
-
-
Cryns, V.1
Yuan, Y.2
-
18
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
Scaffidi, C., Fulda, S., Srinivasan, A. et al. (1998) Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17, 1675-1687
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
-
19
-
-
0031772126
-
The mitochondrial permeability transition is required for tumor necrosis factor α-mediated apoptosis and cytochrome c release
-
Bradham, C. A., Qian, T., Streetz, K., Trautwein, C., Brenner, D. A. and Lemasters, J. J. (1998) The mitochondrial permeability transition is required for tumor necrosis factor α-mediated apoptosis and cytochrome c release. Mol. Cell Biol. 18, 6353-6364
-
(1998)
Mol. Cell Biol.
, vol.18
, pp. 6353-6364
-
-
Bradham, C.A.1
Qian, T.2
Streetz, K.3
Trautwein, C.4
Brenner, D.A.5
Lemasters, J.J.6
-
20
-
-
0035069055
-
Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids
-
Sokol, R. J., Straka, M. S., Dahl, R. et al. (2001) Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr. Res. 49, 519-531
-
(2001)
Pediatr. Res.
, vol.49
, pp. 519-531
-
-
Sokol, R.J.1
Straka, M.S.2
Dahl, R.3
-
21
-
-
0037459081
-
Mitochondria: Releasing power for life and unleashing the machineries of death
-
Cambridge, Mass.
-
Newmeyer, D. D. and Ferguson-Miller, S. (2003) Mitochondria: releasing power for life and unleashing the machineries of death. Cell (Cambridge, Mass.) 112, 481-490
-
(2003)
Cell
, vol.112
, pp. 481-490
-
-
Newmeyer, D.D.1
Ferguson-Miller, S.2
-
22
-
-
0037421221
-
Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis
-
Ricci, J. E., Gottlieb, R. A. and Green, D. R. (2003) Caspase-mediated loss of mitochondrial function and generation of reactive oxygen species during apoptosis. J. Cell Biol. 160, 65-75
-
(2003)
J. Cell Biol.
, vol.160
, pp. 65-75
-
-
Ricci, J.E.1
Gottlieb, R.A.2
Green, D.R.3
-
23
-
-
0037427444
-
Mitochondrial intermembrane proteins in cell death
-
Van Gurp, M., Festjens, N., van Loo, G., Saelens, X. and Vandenabeele, P. (2003) Mitochondrial intermembrane proteins in cell death. Biochem. Biophys. Res. Commun. 304, 487-497
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 487-497
-
-
Van Gurp, M.1
Festjens, N.2
Van Loo, G.3
Saelens, X.4
Vandenabeele, P.5
-
24
-
-
12644291219
-
Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication
-
Kurose, I., Higuchi, H., Miura, S. et al. (1997) Oxidative stress-mediated apoptosis of hepatocytes exposed to acute ethanol intoxication. Hepatology 25, 368-378
-
(1997)
Hepatology
, vol.25
, pp. 368-378
-
-
Kurose, I.1
Higuchi, H.2
Miura, S.3
-
25
-
-
0037218573
-
Oxidative stress in viral and alcoholic hepatitis
-
Loguercio, C. and Federico, A. (2003) Oxidative stress in viral and alcoholic hepatitis. Free Radicals Biol. Med. 34, 1-10
-
(2003)
Free Radicals Biol. Med.
, vol.34
, pp. 1-10
-
-
Loguercio, C.1
Federico, A.2
-
26
-
-
0043135016
-
The role of oxidant stress and reactive nitrogen species in acetaminophen hepatoxicity
-
Jaeschke, H., Knight, T. R. and Bajt, M. L. (2003) The role of oxidant stress and reactive nitrogen species in acetaminophen hepatoxicity. Toxicol. Lett. 144, 279-288
-
(2003)
Toxicol. Lett.
, vol.144
, pp. 279-288
-
-
Jaeschke, H.1
Knight, T.R.2
Bajt, M.L.3
-
27
-
-
0033649270
-
Mechanisms of liver cell injury
-
Kaplowitz, N. (2000) Mechanisms of liver cell injury. J. Hepatol. 32, 39-47
-
(2000)
J. Hepatol.
, vol.32
, pp. 39-47
-
-
Kaplowitz, N.1
-
28
-
-
0032504568
-
The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy
-
Lemasters, J. J., Nieminen, A. L., Qian, T. et al. (1998) The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim. Biophys. Acta 1366, 177-196
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 177-196
-
-
Lemasters, J.J.1
Nieminen, A.L.2
Qian, T.3
-
29
-
-
0037427440
-
Mitochondrial permeability transition: A common pathway to necrosis and apoptosis
-
Kim, J. S., He, L. and Lemasters, J. J. (2003) Mitochondrial permeability transition: a common pathway to necrosis and apoptosis. Biochem. Biophys. Res. Commun. 304, 463-470
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 463-470
-
-
Kim, J.S.1
He, L.2
Lemasters, J.J.3
-
30
-
-
0034644508
-
Insights into programmed cell death through structural biology
-
Cambridge, Mass.
-
Fesik, S. W. (2000) Insights into programmed cell death through structural biology. Cell (Cambridge, Mass.) 103, 273-282
-
(2000)
Cell
, vol.103
, pp. 273-282
-
-
Fesik, S.W.1
-
31
-
-
0032504581
-
Bcl-2 family proteins and mitochondria
-
Reed, J. C., Jurgensmeier, J. M. and Matsuyama, S. (1998) Bcl-2 family proteins and mitochondria. Biochim. Biophys. Acta 1366, 127-137
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 127-137
-
-
Reed, J.C.1
Jurgensmeier, J.M.2
Matsuyama, S.3
-
32
-
-
0042324618
-
Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement
-
Zhao, Y., Ding, W. X., Qian, T., Watkins, S., Lemasters, J. J. and Yin, X. M. (2003) Bid activates multiple mitochondrial apoptotic mechanisms in primary hepatocytes after death receptor engagement. Gastroenterology 125, 854-867
-
(2003)
Gastroenterology
, vol.125
, pp. 854-867
-
-
Zhao, Y.1
Ding, W.X.2
Qian, T.3
Watkins, S.4
Lemasters, J.J.5
Yin, X.M.6
-
33
-
-
0027166048
-
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Cambridge, Mass.
-
Oltvai, Z. N., Milliman, C. L. and Korsmeyer, S. J. (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell (Cambridge, Mass.) 74, 609-619
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
34
-
-
0030995943
-
A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members
-
Diaz, J. L., Oltersdorf, T., Horne, W. et al. (1997) A common binding site mediates heterodimerization and homodimerization of Bcl-2 family members. J. Biol. Chem. 272, 11350-11355
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11350-11355
-
-
Diaz, J.L.1
Oltersdorf, T.2
Horne, W.3
-
35
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
Washington, D.C.
-
Wei, M. C., Zong, W. X., Cheng, E. H. et al. (2001) Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science (Washington, D.C.) 292, 727-730
-
(2001)
Science
, vol.292
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.X.2
Cheng, E.H.3
-
36
-
-
0033607006
-
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis
-
Yin, X. M., Wang, K., Gross, A. et al. (1999) Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis. Nature (London) 400, 886-891
-
(1999)
Nature (London)
, vol.400
, pp. 886-891
-
-
Yin, X.M.1
Wang, K.2
Gross, A.3
-
37
-
-
0033534446
-
L prevents this release but not tumor necrosis factor-R1/Fas death
-
L prevents this release but not tumor necrosis factor-R1/Fas death. J. Biol. Chem. 274, 1156-1163
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1156-1163
-
-
Gross, A.1
Yin, X.M.2
Wang, K.3
-
38
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Cambridge, Mass.
-
Li, H., Zhu, H., Xu, C. J. and Yuan, J. (1998) Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell (Cambridge, Mass.) 94, 491-501
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
39
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter, K. G., Hsu, Y. T., Smith, C. L., Nechushtan, A., Xi, X. G. and Youle, R. J. (1997) Movement of Bax from the cytosol to mitochondria during apoptosis. J. Cell Biol. 139, 1281-1292
-
(1997)
J. Cell Biol.
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.T.2
Smith, C.L.3
Nechushtan, A.4
Xi, X.G.5
Youle, R.J.6
-
40
-
-
0030584088
-
L
-
Cambridge, Mass.
-
L. Cell (Cambridge, Mass.) 87, 619-628
-
(1996)
Cell
, vol.87
, pp. 619-628
-
-
Zha, J.1
Harada, H.2
Yang, E.3
Jockel, J.4
Korsmeyer, S.J.5
-
41
-
-
0032146987
-
Bcl-2-family proteins: The role of the BH3 domain in apoptosis
-
Kelekar, A. and Thompson, C. B. (1998) Bcl-2-family proteins: the role of the BH3 domain in apoptosis. Trends Cell Biol. 8, 324-330
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
42
-
-
0037151030
-
Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with proapoptotic Bak or Bax
-
Werner, A. B., de Vries, E., Tait, S. W., Bontjer, I. and Borst, J. (2002) Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with proapoptotic Bak or Bax. J. Biol. Chem. 277, 22781-22788
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 22781-22788
-
-
Werner, A.B.1
De Vries, E.2
Tait, S.W.3
Bontjer, I.4
Borst, J.5
-
44
-
-
0037192790
-
L inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein
-
L inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein. J. Biol. Chem. 277, 11345-11351
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11345-11351
-
-
Sun, X.M.1
Bratton, S.B.2
Butterworth, M.3
MacFarlane, M.4
Cohen, G.M.5
-
45
-
-
0033258120
-
Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
-
Vander Heiden, M. G. and Thompson, C. B. (1999) Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nat. Cell Biol. 1, E209-E216
-
(1999)
Nat. Cell Biol.
, vol.1
-
-
Vander Heiden, M.G.1
Thompson, C.B.2
-
46
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Cambridge, Mass.
-
Li, P., Nijhawan, D., Budihardjo, I. et al. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell (Cambridge, Mass.) 91, 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
-
47
-
-
0032785181
-
Serial killers: Ordering caspase activation events in apoptosis
-
Slee, E. A., Adrain, C. and Martin, S. J. (1999) Serial killers: ordering caspase activation events in apoptosis. Cell Death Differ. 6, 1067-1074
-
(1999)
Cell Death Differ.
, vol.6
, pp. 1067-1074
-
-
Slee, E.A.1
Adrain, C.2
Martin, S.J.3
-
48
-
-
0038182531
-
Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3
-
Degli, E. M., Ferry, G., Masdehors, P., Boutin, J. A., Hickman, J. A. and Dive, C. (2003) Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3. J. Biol. Chem. 278, 15749-15757
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15749-15757
-
-
Degli, E.M.1
Ferry, G.2
Masdehors, P.3
Boutin, J.A.4
Hickman, J.A.5
Dive, C.6
-
49
-
-
0034194338
-
Caspase-2 is localized at the Golgi complex and cleaves Golgin-160 during apoptosis
-
Mancini, M., Machamer, C. E., Roy, S. et al. (2000) Caspase-2 is localized at the Golgi complex and cleaves Golgin-160 during apoptosis. J. Cell Biol. 149, 603-612
-
(2000)
J. Cell Biol.
, vol.149
, pp. 603-612
-
-
Mancini, M.1
Machamer, C.E.2
Roy, S.3
-
50
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
-
Nakagawa, T., Zhu, H., Morishima, N., Li, E., Xu, J., Yankner, B. A. and Yuan, J. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β. Nature (London) 403, 98-103
-
(2000)
Nature (London)
, vol.403
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
51
-
-
0032559799
-
The caspase-3 precursor has a cytosolic and mitochondrial distribution: Implications for apoptotic signaling
-
Mancini, M., Nicholson, D. W., Roy, S. et al. (1998) The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling. J. Cell Biol. 140, 1485-1495
-
(1998)
J. Cell Biol.
, vol.140
, pp. 1485-1495
-
-
Mancini, M.1
Nicholson, D.W.2
Roy, S.3
-
52
-
-
18244387009
-
Pre-processed caspase-9 contained in mitochondria participates in apoptosis
-
Constantini, P., Bruey, J. M., Castedo, M. et al. (2002) Pre-processed caspase-9 contained in mitochondria participates in apoptosis. Cell Death Differ. 9, 82-88
-
(2002)
Cell Death Differ.
, vol.9
, pp. 82-88
-
-
Constantini, P.1
Bruey, J.M.2
Castedo, M.3
-
53
-
-
0036848165
-
Caspases are not localized in mitochondria during life or death
-
van Loo, G., Saelens, X., Matthijssens, F., Schotte, P., Beyaert, R., Declercq, W. and Vandenabeele, P. (2002) Caspases are not localized in mitochondria during life or death. Cell Death Differ. 9, 1207-1211
-
(2002)
Cell Death Differ.
, vol.9
, pp. 1207-1211
-
-
Van Loo, G.1
Saelens, X.2
Matthijssens, F.3
Schotte, P.4
Beyaert, R.5
Declercq, W.6
Vandenabeele, P.7
-
54
-
-
0033521741
-
Molecular characterization of mitochondrial apoptosis-inducing factor
-
Susin, S. A., Lorenzo, H. K., Zamzami, N. et al. (1999) Molecular characterization of mitochondrial apoptosis-inducing factor. Nature (London) 397, 441-446
-
(1999)
Nature (London)
, vol.397
, pp. 441-446
-
-
Susin, S.A.1
Lorenzo, H.K.2
Zamzami, N.3
-
55
-
-
0035674047
-
Endonuclease G: A mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation
-
van Loo, G., Schotte, P., van Gurp, M. et al. (2001) Endonuclease G: a mitochondrial protein released in apoptosis and involved in caspase-independent DNA degradation. Cell Death Differ. 8, 1136-1142
-
(2001)
Cell Death Differ.
, vol.8
, pp. 1136-1142
-
-
Van Loo, G.1
Schotte, P.2
Van Gurp, M.3
-
56
-
-
0035803568
-
Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2
-
Adrain, C., Creagh, E. M. and Martin, S. J. (2001) Apoptosis-associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl-2. EMBO J. 20, 6627-6636
-
(2001)
EMBO J.
, vol.20
, pp. 6627-6636
-
-
Adrain, C.1
Creagh, E.M.2
Martin, S.J.3
-
57
-
-
0037380884
-
Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria
-
Yamaguchi, H., Bhalla, K. and Wang, H. G. (2003) Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria. Cancer Res. 63, 1483-1489
-
(2003)
Cancer Res.
, vol.63
, pp. 1483-1489
-
-
Yamaguchi, H.1
Bhalla, K.2
Wang, H.G.3
-
58
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Cambridge, Mass.
-
Verhagen, A. M., Ekert, P. G., Pakusch, M. et al. (2000) Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell (Cambridge, Mass.) 102, 43-53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
-
59
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Cambridge, Mass.
-
Du, C., Fang, M., Li, Y., Li, L. and Wang, X. (2000) Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell (Cambridge, Mass.) 102, 33-42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
60
-
-
0037016686
-
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
-
Verhagen, A. M., Silke, J., Ekert, P. G. et al. (2002) HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. J. Biol. Chem. 277, 445-454
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 445-454
-
-
Verhagen, A.M.1
Silke, J.2
Ekert, P.G.3
-
61
-
-
0027936174
-
Endotoxin causes early changes in glutathione concentrations in rabbit plasma and liver
-
Okabe, H., Irita, K., Taniguchi, S., Kurosawa, K., Tagawa, K., Yoshitake, J. and Takahashi, S. (1994) Endotoxin causes early changes in glutathione concentrations in rabbit plasma and liver. J. Surg. Res. 57, 416-419
-
(1994)
J. Surg. Res.
, vol.57
, pp. 416-419
-
-
Okabe, H.1
Irita, K.2
Taniguchi, S.3
Kurosawa, K.4
Tagawa, K.5
Yoshitake, J.6
Takahashi, S.7
-
62
-
-
0031763795
-
Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor toxicity
-
Xu, Y., Jones, B. E., Neufeld, D. S. and Czaja, M. J. (1998) Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor toxicity. Gastroenterology 115, 1229-1237
-
(1998)
Gastroenterology
, vol.115
, pp. 1229-1237
-
-
Xu, Y.1
Jones, B.E.2
Neufeld, D.S.3
Czaja, M.J.4
-
63
-
-
0032998834
-
Molecular regulation of hepatocellular transport systems in cholestasis
-
Trauner, M., Meier, P. J. and Boyer, J. L. (1999) Molecular regulation of hepatocellular transport systems in cholestasis. J. Hepatol. 31, 165-178
-
(1999)
J. Hepatol.
, vol.31
, pp. 165-178
-
-
Trauner, M.1
Meier, P.J.2
Boyer, J.L.3
-
64
-
-
0141814990
-
Tumor necrosis factor α-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis
-
Bohan, A., Chen, W. S., Denson, L. A., Held, M. A. and Boyer, J. L. (2003) Tumor necrosis factor α-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. J. Biol. Chem. 278, 36688-36698
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36688-36698
-
-
Bohan, A.1
Chen, W.S.2
Denson, L.A.3
Held, M.A.4
Boyer, J.L.5
-
65
-
-
0034007745
-
Liver regeneration
-
Fausto, N. (2000) Liver regeneration. J. Hepatol. 32, 19-31
-
(2000)
J. Hepatol.
, vol.32
, pp. 19-31
-
-
Fausto, N.1
-
66
-
-
0037213389
-
The role of hepatocytes and oval cells in liver regeneration and repopulation
-
Fausto, N. and Campbell, J. S. (2003) The role of hepatocytes and oval cells in liver regeneration and repopulation. Mech. Dev. 120, 117-130
-
(2003)
Mech. Dev.
, vol.120
, pp. 117-130
-
-
Fausto, N.1
Campbell, J.S.2
-
67
-
-
0031682110
-
Mechanisms of hepatic toxicity. I. TNF-induced liver injury
-
Bradham, C. A., Plumpe, J., Manns, M. P., Brenner, D. A. and Trautwein, C. (1998) Mechanisms of hepatic toxicity. I. TNF-induced liver injury. Am. J. Physiol. 275, G387-G392
-
(1998)
Am. J. Physiol.
, vol.275
-
-
Bradham, C.A.1
Plumpe, J.2
Manns, M.P.3
Brenner, D.A.4
Trautwein, C.5
-
68
-
-
0029976817
-
An essential role for NF-κB in preventing TNF-α-induced cell death
-
Washington, D.C.
-
Beg, A. A. and Baltimore, D. (1996) An essential role for NF-κB in preventing TNF-α-induced cell death. Science (Washington, D.C.) 274, 782-784
-
(1996)
Science
, vol.274
, pp. 782-784
-
-
Beg, A.A.1
Baltimore, D.2
-
69
-
-
0029992609
-
Suppression of TNF-α-induced apoptosis by NF-κ-B
-
Washington, D.C.
-
Van Antwerp, D. J., Martin, S. J., Kafri, T., Green, D. R. and Verma, I. M. (1996) Suppression of TNF-α-induced apoptosis by NF-κ-B. Science (Washington, D.C.) 274, 787-789
-
(1996)
Science
, vol.274
, pp. 787-789
-
-
Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
-
70
-
-
0042525938
-
NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
-
Sakon, S., Xue, X., Takekawa, M. et al. (2003) NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J. 22, 3898-3909
-
(2003)
EMBO J.
, vol.22
, pp. 3898-3909
-
-
Sakon, S.1
Xue, X.2
Takekawa, M.3
-
71
-
-
0030817061
-
Inhibition of NF-κB activity induces apoptosis in murine hepatocytes
-
Bellas, R. E., FitzGerald, M. J., Fausto, N. and Sonenshein, G. E. (1997) Inhibition of NF-κB activity induces apoptosis in murine hepatocytes. Am. J. Pathol. 151, 891-896
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 891-896
-
-
Bellas, R.E.1
FitzGerald, M.J.2
Fausto, N.3
Sonenshein, G.E.4
-
72
-
-
17544365995
-
The IκB/NF-κB system: A key determinant of mucosalinflammation and protection
-
Jobin, C. and Sartor, R. B. (2000) The IκB/NF-κB system: a key determinant of mucosalinflammation and protection. Am. J. Physiol. Cell Physiol. 278, C451-C462
-
(2000)
Am. J. Physiol. Cell Physiol.
, vol.278
-
-
Jobin, C.1
Sartor, R.B.2
-
73
-
-
0038601994
-
Evidence that reactive oxygen species do not mediate NF-κB activation
-
Hayakawa, M., Miyashita, H., Sakamoto, I. et al. (2003) Evidence that reactive oxygen species do not mediate NF-κB activation. EMBO J. 22, 3356-3366
-
(2003)
EMBO J.
, vol.22
, pp. 3356-3366
-
-
Hayakawa, M.1
Miyashita, H.2
Sakamoto, I.3
-
74
-
-
0031044832
-
Redox regulation of NF-κB activation
-
Flohe, E., Brigelius-Flohe, R., Saliou, C., Traber, M. G. and Packer, L. (1997) Redox regulation of NF-κB activation. Free Radicals Biol. Med. 22, 1115-1126
-
(1997)
Free Radicals Biol. Med.
, vol.22
, pp. 1115-1126
-
-
Flohe, E.1
Brigelius-Flohe, R.2
Saliou, C.3
Traber, M.G.4
Packer, L.5
-
75
-
-
0033607313
-
The NF-κB activation pathway: A paradigm in information transfer from membrane to nucleus
-
Rothwarf, D. M. and Karin, M. (1999) The NF-κB activation pathway: a paradigm in information transfer from membrane to nucleus. Sci. STKE, RE1
-
(1999)
Sci. STKE
-
-
Rothwarf, D.M.1
Karin, M.2
-
76
-
-
0033119952
-
Embryonic lethality, liver degeneration, and impaired NF-κ-B activation in IKK-β-deficient mice
-
Tanaka, M., Fuentes, M. E., Yamaguchi, K. et al. (1999) Embryonic lethality, liver degeneration, and impaired NF-κ-B activation in IKK-β-deficient mice. Immunity 10, 421-429
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
Fuentes, M.E.2
Yamaguchi, K.3
-
77
-
-
0033002197
-
Bridging the gap: Composition, regulation, and physiological function of the Iκ-B kinase complex
-
Zandi, E. and Karin, M. (1999) Bridging the gap: composition, regulation, and physiological function of the Iκ-B kinase complex. Mol. Cell Biol. 19, 4547-4551
-
(1999)
Mol. Cell Biol.
, vol.19
, pp. 4547-4551
-
-
Zandi, E.1
Karin, M.2
-
78
-
-
0037044896
-
Signal transduction. Decoding NF-κB signaling
-
Washington, D.C.
-
Ting, A. Y. and Endy, D. (2002) Signal transduction. Decoding NF-κB signaling. Science (Washington, D.C.) 298, 1189-1190
-
(2002)
Science
, vol.298
, pp. 1189-1190
-
-
Ting, A.Y.1
Endy, D.2
-
79
-
-
0037044575
-
The IκB-NF-κB signaling module: Temporal control and selective gene activation
-
Washington, D.C.
-
Hoffmann, A., Levchenko, A., Scott, M. L. and Baltimore, D. (2002) The IκB-NF-κB signaling module: temporal control and selective gene activation. Science (Washington, D.C.) 298, 1241-1245
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
80
-
-
0033027275
-
Expression of inducible nitric oxide synthase in endotoxemic rat hepatocytes is dependent on the cellular glutathione status
-
Vos, T. A., Van Goor, H., Tuyt, E. et al. (1999) Expression of inducible nitric oxide synthase in endotoxemic rat hepatocytes is dependent on the cellular glutathione status. Hepatology 29, 421-426
-
(1999)
Hepatology
, vol.29
, pp. 421-426
-
-
Vos, T.A.1
Van Goor, H.2
Tuyt, E.3
-
81
-
-
0036623358
-
Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-κB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis
-
Schoemaker, M. H., Ros, J. E., Homan, M. et al. (2002) Cytokine regulation of pro- and anti-apoptotic genes in rat hepatocytes: NF-κB-regulated inhibitor of apoptosis protein 2 (cIAP2) prevents apoptosis. J. Hepatol. 36, 742-750
-
(2002)
J. Hepatol.
, vol.36
, pp. 742-750
-
-
Schoemaker, M.H.1
Ros, J.E.2
Homan, M.3
-
82
-
-
0033082995
-
IAP family proteins: Suppressors of apoptosis
-
Deveraux, Q. L. and Reed, J. C. (1999) IAP family proteins: suppressors of apoptosis. Genes Dev. 13, 239-252
-
(1999)
Genes Dev.
, vol.13
, pp. 239-252
-
-
Deveraux, Q.L.1
Reed, J.C.2
-
83
-
-
0034282432
-
The inhibitor of apoptosis, cIAP 2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang, H., Joazeiro, C. A., Bonfoco, E., Kamada, S., Leverson, J. D. and Hunter, T. (2000) The inhibitor of apoptosis, cIAP 2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Chem. 275, 26661-26664
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
Joazeiro, C.A.2
Bonfoco, E.3
Kamada, S.4
Leverson, J.D.5
Hunter, T.6
-
84
-
-
0030885421
-
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control
-
Chu, Z. L., McKinsey, T. A., Liu, L., Gentry, J. J., Malim, M. H. and Ballard, D. W. (1997) Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control. Proc. Natl. Acad. Sci. U.S.A. 94, 10057-10062
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 10057-10062
-
-
Chu, Z.L.1
McKinsey, T.A.2
Liu, L.3
Gentry, J.J.4
Malim, M.H.5
Ballard, D.W.6
-
85
-
-
0032508414
-
NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
-
Washington, D.C.
-
Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V. and Baldwin, Jr, A. S. (1998) NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science (Washington, D.C.) 281, 1680-1683
-
(1998)
Science
, vol.281
, pp. 1680-1683
-
-
Wang, C.Y.1
Mayo, M.W.2
Korneluk, R.G.3
Goeddel, D.V.4
Baldwin Jr., A.S.5
-
86
-
-
0035282334
-
Mammalian MAP kinase signalling cascades
-
Chang, L. and Karin, M. (2001) Mammalian MAP kinase signalling cascades. Nature (London) 410, 37-40
-
(2001)
Nature (London)
, vol.410
, pp. 37-40
-
-
Chang, L.1
Karin, M.2
-
87
-
-
0033950358
-
The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor α-mediated rat hepatocyte survival and apoptosis
-
Roberts, R. A., James, N. H. and Cosulich, S. C. (2000) The role of protein kinase B and mitogen-activated protein kinase in epidermal growth factor and tumor necrosis factor α-mediated rat hepatocyte survival and apoptosis. Hepatology 31, 420-427
-
(2000)
Hepatology
, vol.31
, pp. 420-427
-
-
Roberts, R.A.1
James, N.H.2
Cosulich, S.C.3
-
88
-
-
0036151709
-
Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes
-
Rao, Y. P., Studer, E. J., Stravitz, R. T., Gupta, S., Qiao, L., Dent, P. and Hylemon, P. B. (2002) Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes. Hepatology 35, 307-314
-
(2002)
Hepatology
, vol.35
, pp. 307-314
-
-
Rao, Y.P.1
Studer, E.J.2
Stravitz, R.T.3
Gupta, S.4
Qiao, L.5
Dent, P.6
Hylemon, P.B.7
-
89
-
-
0029935418
-
Regulation of transcription by MAP kinase cascades
-
Treisman, R. (1996) Regulation of transcription by MAP kinase cascades. Curr. Opin. Cell Biol. 8, 205-215
-
(1996)
Curr. Opin. Cell Biol.
, vol.8
, pp. 205-215
-
-
Treisman, R.1
-
90
-
-
0032488837
-
p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor
-
Vanden Berghe, W., Plaisance, S., Boone, E. et al. (1998) p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways are required for nuclear factor-κB p65 transactivation mediated by tumor necrosis factor. J. Biol. Chem. 273, 3285-3290
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3285-3290
-
-
Vanden Berghe, W.1
Plaisance, S.2
Boone, E.3
-
91
-
-
0041328359
-
The phosphoinositide (PI) 3-kinase family
-
Foster, F. M., Traer, C. J., Abraham, S. M. and Fry, M. J. (2003) The phosphoinositide (PI) 3-kinase family. J. Cell Sci. 116, 3037-3040
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3037-3040
-
-
Foster, F.M.1
Traer, C.J.2
Abraham, S.M.3
Fry, M.J.4
-
92
-
-
0033605718
-
The role of phosphoinositide 3-kinase lipid products in cell function
-
Rameh, L. E. and Cantley, L. C. (1999) The role of phosphoinositide 3-kinase lipid products in cell function. J. Biol. Chem. 274, 8347-8350
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8347-8350
-
-
Rameh, L.E.1
Cantley, L.C.2
-
93
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta, S. R., Brunet, A. and Greenberg, M. E. (1999) Cellular survival: a play in three Akts. Genes Dev. 13, 2905-2927
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
94
-
-
0033517244
-
Akt is more than just a Bad kinase
-
Khwaja, A. (1999) Akt is more than just a Bad kinase. Nature (London) 401, 33-34
-
(1999)
Nature (London)
, vol.401
, pp. 33-34
-
-
Khwaja, A.1
-
95
-
-
2442702177
-
Bile acids induce survival signals in hepatic stellate cells through a PKC- and ERK-dependent mechanism
-
Svegliati-Baroni, L., Ridolfi, F., Schoemaker, M. H. et al. (2002) Bile acids induce survival signals in hepatic stellate cells through a PKC- and ERK-dependent mechanism. Hepatology 36 (suppl. 2), 316A
-
(2002)
Hepatology
, vol.36
, Issue.2 SUPPL.
-
-
Svegliati-Baroni, L.1
Ridolfi, F.2
Schoemaker, M.H.3
-
96
-
-
2142726023
-
Anti-tumor necrosis factor-α therapy during murine Klebsiella pneumoniae bacteremia: Increased mortality in the absence of liver injury
-
Moore, T. A., Lau, H. Y., Cogen, A. L., Monteleon, C. L. and Standiford, T. J. (2003) Anti-tumor necrosis factor-α therapy during murine Klebsiella pneumoniae bacteremia: increased mortality in the absence of liver injury. Shock 20, 309-315
-
(2003)
Shock
, vol.20
, pp. 309-315
-
-
Moore, T.A.1
Lau, H.Y.2
Cogen, A.L.3
Monteleon, C.L.4
Standiford, T.J.5
-
97
-
-
0037902193
-
Die another day. Beyond the journal
-
Schoemaker, M. H. and Moshage, H. (2003) Die another day. Beyond the journal. J. Hepatol. 38, 873-875
-
(2003)
J. Hepatol.
, vol.38
, pp. 873-875
-
-
Schoemaker, M.H.1
Moshage, H.2
-
98
-
-
0032723336
-
Kupffer cell blockade, tumour necrosis factor secretion and survival following endotoxin challenge in experimental biliary obstruction
-
Kennedy, J. A., Lewis, H., Clements, W. D. et al. (1999) Kupffer cell blockade, tumour necrosis factor secretion and survival following endotoxin challenge in experimental biliary obstruction. Br. J. Surg. 86, 1410-1414
-
(1999)
Br. J. Surg.
, vol.86
, pp. 1410-1414
-
-
Kennedy, J.A.1
Lewis, H.2
Clements, W.D.3
-
99
-
-
0034802467
-
Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats
-
Melgert, B. N., Olinga, P., Van Der Laan, J. M. et al. (2001) Targeting dexamethasone to Kupffer cells: effects on liver inflammation and fibrosis in rats. Hepatology 34, 719-728
-
(2001)
Hepatology
, vol.34
, pp. 719-728
-
-
Melgert, B.N.1
Olinga, P.2
Van Der Laan, J.M.3
-
100
-
-
0032869839
-
Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas
-
Miyoshi, H., Rust, C., Roberts, P. J., Burgart, L. J. and Gores, G. J. (1999) Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas. Gastroenterology 117, 669-677
-
(1999)
Gastroenterology
, vol.117
, pp. 669-677
-
-
Miyoshi, H.1
Rust, C.2
Roberts, P.J.3
Burgart, L.J.4
Gores, G.J.5
-
101
-
-
0034745492
-
NF-κB is activated in cholestasis and functions to reduce liver injury
-
Miyoshi, H., Rust, C., Guicciardi, M. E. and Gores, G. J. (2001) NF-κB is activated in cholestasis and functions to reduce liver injury. Am. J. Pathol. 158, 967-975
-
(2001)
Am. J. Pathol.
, vol.158
, pp. 967-975
-
-
Miyoshi, H.1
Rust, C.2
Guicciardi, M.E.3
Gores, G.J.4
-
102
-
-
0042766884
-
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice
-
Gujral, J. S., Farhood, A., Bajt, M. L. and Jaeschke, H. (2003) Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct-ligated mice. Hepatology 38, 355-363
-
(2003)
Hepatology
, vol.38
, pp. 355-363
-
-
Gujral, J.S.1
Farhood, A.2
Bajt, M.L.3
Jaeschke, H.4
-
103
-
-
0036725044
-
Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited
-
Paumgartner, G. and Beuers, U. (2002) Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited. Hepatology 36, 525-531
-
(2002)
Hepatology
, vol.36
, pp. 525-531
-
-
Paumgartner, G.1
Beuers, U.2
-
104
-
-
0037452957
-
Tauroursodeoxycholic acid prevents bax-induced membrane perturbation and cytochrome c relace in isolated mitochondria
-
Rodrigues, C. M., Sola, S., Sharpe, J. C., Moura, J. J. and Steer, C. J. (2003) Tauroursodeoxycholic acid prevents bax-induced membrane perturbation and cytochrome c relace in isolated mitochondria. Biochemistry 42, 3070-3080
-
(2003)
Biochemistry
, vol.42
, pp. 3070-3080
-
-
Rodrigues, C.M.1
Sola, S.2
Sharpe, J.C.3
Moura, J.J.4
Steer, C.J.5
-
105
-
-
2442662132
-
TUDCA protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways
-
in the press
-
Schoemaker, M. H., Conde de la Rosa, L., Buist-Homan, M. et al. (2004) TUDCA protects rat hepatocytes from bile acid-induced apoptosis via activation of survival pathways. Hepatology, in the press
-
(2004)
Hepatology
-
-
Schoemaker, M.H.1
Conde De La Rosa, L.2
Buist-Homan, M.3
-
106
-
-
0031983188
-
Vitamin E reduces oxidant injury to mitochondria and hepatoxicity of intravenous taurochenodeoxycholic acid in the rat
-
Sokol, R. J., McKim, J. M., Goff, M. C. et al. (1998) Vitamin E reduces oxidant injury to mitochondria and hepatoxicity of intravenous taurochenodeoxycholic acid in the rat. Gastroenterology 114, 164-174
-
(1998)
Gastroenterology
, vol.114
, pp. 164-174
-
-
Sokol, R.J.1
McKim, J.M.2
Goff, M.C.3
-
107
-
-
0842305753
-
Glutathione protects rat liver against reperfusion injury after prolonged warm ischemia
-
Schauer, R. J., Gerbes, A. L., Vonier, D. et al. (2004) Glutathione protects rat liver against reperfusion injury after prolonged warm ischemia. Ann. Surg. 239, 220-231
-
(2004)
Ann. Surg.
, vol.239
, pp. 220-231
-
-
Schauer, R.J.1
Gerbes, A.L.2
Vonier, D.3
-
108
-
-
0037418609
-
Redox control of hepatic cell death
-
Hentze, H., Latta, M., Kunstle, G., Lucas, R. and Wendel, A. (2003) Redox control of hepatic cell death. Toxicol. Lett. 139, 111-118
-
(2003)
Toxicol. Lett.
, vol.139
, pp. 111-118
-
-
Hentze, H.1
Latta, M.2
Kunstle, G.3
Lucas, R.4
Wendel, A.5
-
109
-
-
0032146551
-
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
-
Iredale, J. P., Benyon, R. C., Pickering, J. et al. (1998) Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J. Clin. Invest. 102, 538-549
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 538-549
-
-
Iredale, J.P.1
Benyon, R.C.2
Pickering, J.3
-
110
-
-
0034830886
-
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
-
Wright, M. C., Issa, R., Smart, D. E. et al. (2001) Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 121, 685-698
-
(2001)
Gastroenterology
, vol.121
, pp. 685-698
-
-
Wright, M.C.1
Issa, R.2
Smart, D.E.3
-
111
-
-
0042200304
-
Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model
-
Dekel, R., Zvibel, I., Brill, S., Brazovsky, E., Halpern, Z. and Oren, R. (2003) Gliotoxin ameliorates development of fibrosis and cirrhosis in a thioacetamide rat model. Dig. Dis. Sci. 48, 1642-1647
-
(2003)
Dig. Dis. Sci.
, vol.48
, pp. 1642-1647
-
-
Dekel, R.1
Zvibel, I.2
Brill, S.3
Brazovsky, E.4
Halpern, Z.5
Oren, R.6
-
112
-
-
0141740706
-
The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue
-
Beljaars, L., Weert, B., Geerts, A., Meijer, D. K. and Poelstra, K. (2003) The preferential homing of a platelet derived growth factor receptor-recognizing macromolecule to fibroblast-like cells in fibrotic tissue. Biochem. Pharmacol. 66, 1307-1317
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 1307-1317
-
-
Beljaars, L.1
Weert, B.2
Geerts, A.3
Meijer, D.K.4
Poelstra, K.5
-
113
-
-
84862673523
-
Redirection of PDGF-receptor targeted adenovirus from hepatocytes to activated stellate cells
-
Schoemaker, M. H., Rots, M. G., Beljaars, L. et al. (2003) Redirection of PDGF-receptor targeted adenovirus from hepatocytes to activated stellate cells. Hepatology 38 (suppl. 2), A143
-
(2003)
Hepatology
, vol.38
, Issue.2 SUPPL.
-
-
Schoemaker, M.H.1
Rots, M.G.2
Beljaars, L.3
-
114
-
-
0033623899
-
Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells
-
Lang, A., Schoonhoven, R., Tuvia, S., Brenner, D. A. and Rippe, R. A. (2000) Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells. J. Hepatol. 33, 49-58
-
(2000)
J. Hepatol.
, vol.33
, pp. 49-58
-
-
Lang, A.1
Schoonhoven, R.2
Tuvia, S.3
Brenner, D.A.4
Rippe, R.A.5
-
115
-
-
0031752146
-
Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes
-
Mignon, A., Guidotti, J. E., Mitchell, C. et al. (1998) Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes. Nat. Med. 4, 1185-1188
-
(1998)
Nat. Med.
, vol.4
, pp. 1185-1188
-
-
Mignon, A.1
Guidotti, J.E.2
Mitchell, C.3
-
116
-
-
0028878716
-
Expression of bcl-2 inhibits necrotic neural cell death
-
Kane, D. J., Ord, T., Anton, R. and Bredesen, D. E. (1995) Expression of bcl-2 inhibits necrotic neural cell death. J. Neurosci. Res. 40, 269-275
-
(1995)
J. Neurosci. Res.
, vol.40
, pp. 269-275
-
-
Kane, D.J.1
Ord, T.2
Anton, R.3
Bredesen, D.E.4
-
117
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
Deveraux, Q. L., Roy, N., Stennicke, H. R. et al. (1998) IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17, 2215-2223
-
(1998)
EMBO J.
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
-
118
-
-
0035884041
-
Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis
-
Bajt, M. L., Vonderfecht, S. L. and Jaeschke, H. (2001) Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis. Toxicol. Appl. Pharmacol. 175, 243-252
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.175
, pp. 243-252
-
-
Bajt, M.L.1
Vonderfecht, S.L.2
Jaeschke, H.3
-
119
-
-
0033855570
-
Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure
-
Streetz, K., Leifeld, L., Grundmann, D. et al. (2000) Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure. Gastroenterology 119, 446-460
-
(2000)
Gastroenterology
, vol.119
, pp. 446-460
-
-
Streetz, K.1
Leifeld, L.2
Grundmann, D.3
-
120
-
-
0042809497
-
Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma
-
Okano, H., Shiraki, K., Inoue, H. et al. (2003) Cellular FLICE/caspase-8-inhibitory protein as a principal regulator of cell death and survival in human hepatocellular carcinoma. Lab. Invest. 83, 1033-1043
-
(2003)
Lab. Invest.
, vol.83
, pp. 1033-1043
-
-
Okano, H.1
Shiraki, K.2
Inoue, H.3
-
121
-
-
0032708392
-
The anti-apoptotic actions of nitric oxide in hepatocytes
-
Li, J. and Billiar, T. R. (1999) The anti-apoptotic actions of nitric oxide in hepatocytes. Cell Death Differ. 6, 952-955
-
(1999)
Cell Death Differ.
, vol.6
, pp. 952-955
-
-
Li, J.1
Billiar, T.R.2
-
122
-
-
0031855881
-
Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis
-
Tzeng, E., Billiar, T. R., Williams, D. L. et al. (1998) Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis. Surgery 124, 278-283
-
(1998)
Surgery
, vol.124
, pp. 278-283
-
-
Tzeng, E.1
Billiar, T.R.2
Williams, D.L.3
-
123
-
-
0031431194
-
Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia
-
Ou, J., Carlos, T. M., Watkins, S. C. et al. (1997) Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia. Nitric Oxide 1, 404-416
-
(1997)
Nitric Oxide
, vol.1
, pp. 404-416
-
-
Ou, J.1
Carlos, T.M.2
Watkins, S.C.3
-
124
-
-
0030918451
-
Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-α-induced apoptosis and toxicity in the liver
-
Saavedra, J. E., Billiar, T. R., Williams, D. L., Kim, Y. M., Watkins, S. C. and Keefer, L. K. (1997) Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-α-induced apoptosis and toxicity in the liver. J. Med. Chem. 40, 1947-1954
-
(1997)
J. Med. Chem.
, vol.40
, pp. 1947-1954
-
-
Saavedra, J.E.1
Billiar, T.R.2
Williams, D.L.3
Kim, Y.M.4
Watkins, S.C.5
Keefer, L.K.6
-
125
-
-
0037308128
-
The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen- induced hepatotoxicity in mice
-
Liu, J., Li, C., Waalkes, M. P., Clark, J., Myers, P., Saavedra, J. E. and Keefer, L. K. (2003) The nitric oxide donor, V-PYRRO/NO, protects against acetaminophen-induced hepatotoxicity in mice. Hepatology 37, 324-333
-
(2003)
Hepatology
, vol.37
, pp. 324-333
-
-
Liu, J.1
Li, C.2
Waalkes, M.P.3
Clark, J.4
Myers, P.5
Saavedra, J.E.6
Keefer, L.K.7
-
126
-
-
0029243372
-
The role of nitric oxide in Kupffer cell-hepatocyte interactions
-
Harbrecht, B. G. and Billiar, T. R. (1995) The role of nitric oxide in Kupffer cell-hepatocyte interactions. Shock 3, 79-87
-
(1995)
Shock
, vol.3
, pp. 79-87
-
-
Harbrecht, B.G.1
Billiar, T.R.2
-
127
-
-
0035078936
-
Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats
-
Wheeler, M. D., Kono, H., Yin, M. et al. (2001) Delivery of the Cu/Zn-superoxide dismutase gene with adenovirus reduces early alcohol-induced liver injury in rats. Gastroenterology 120, 1241-1250
-
(2001)
Gastroenterology
, vol.120
, pp. 1241-1250
-
-
Wheeler, M.D.1
Kono, H.2
Yin, M.3
-
128
-
-
0036190844
-
Viral gene delivery of superoxide dismutase attenuates experimental cholestasis-induced liver fibrosis in the rat
-
Zhong, Z., Froh, M., Wheeler, M. D., Smutney, O., Lehmann, T. G. and Thurman, R. G. (2002) Viral gene delivery of superoxide dismutase attenuates experimental cholestasis-induced liver fibrosis in the rat. Gene Ther. 9, 183-191
-
(2002)
Gene Ther.
, vol.9
, pp. 183-191
-
-
Zhong, Z.1
Froh, M.2
Wheeler, M.D.3
Smutney, O.4
Lehmann, T.G.5
Thurman, R.G.6
-
129
-
-
0037348329
-
RNA interference targeting Fas protects mice from fulminant hepatitis
-
Song, E., Lee, S. K., Wang, J. et al. (2003) RNA interference targeting Fas protects mice from fulminant hepatitis. Nat. Med. 9, 347-351
-
(2003)
Nat. Med.
, vol.9
, pp. 347-351
-
-
Song, E.1
Lee, S.K.2
Wang, J.3
-
130
-
-
0038610713
-
Caspase-8 small interfering RNA prevents acute liver failure in mice
-
Zender, L., Hütker, S., Liedtke, C. et al. (2003) Caspase-8 small interfering RNA prevents acute liver failure in mice. Proc. Natl. Acad. Sci. U.S.A. 100, 7797-7802
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 7797-7802
-
-
Zender, L.1
Hütker, S.2
Liedtke, C.3
-
131
-
-
1442326154
-
SiRNA based strategies for inhibition of aoptotic pathways in vivo: Analytical and therapeutic implications
-
Zender, L. and Kubicka, S. (2004) SiRNA based strategies for inhibition of aoptotic pathways in vivo: analytical and therapeutic implications. Apoptosis 9, 51-54
-
(2004)
Apoptosis
, vol.9
, pp. 51-54
-
-
Zender, L.1
Kubicka, S.2
-
132
-
-
0037962912
-
Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy
-
Xue, F., Takahara, T., Yata, Y. et al. (2003) Hepatocyte growth factor gene therapy accelerates regeneration in cirrhotic mouse livers after hepatectomy. Gut 52, 694-700
-
(2003)
Gut
, vol.52
, pp. 694-700
-
-
Xue, F.1
Takahara, T.2
Yata, Y.3
-
133
-
-
0037414727
-
A single administration of adenoviral-mediated HGF cDNA permits survival of mice from acute hepatic failure
-
Hwang, T. H., Yoon, B. C., Jeong, J. S., Seo, S. Y. and Lee, H. Y. (2003) A single administration of adenoviral-mediated HGF cDNA permits survival of mice from acute hepatic failure. Life Sci. 72, 851-861
-
(2003)
Life Sci.
, vol.72
, pp. 851-861
-
-
Hwang, T.H.1
Yoon, B.C.2
Jeong, J.S.3
Seo, S.Y.4
Lee, H.Y.5
-
134
-
-
12144288466
-
Hepatocyte growth factor induces mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt
-
Schulze-Bergkamen, H., Brenner, D., Krueger, A. et al. (2004) Hepatocyte growth factor induces mcl-1 in primary human hepatocytes and inhibits CD95-mediated apoptosis via Akt. Hepatology 39, 645-654
-
(2004)
Hepatology
, vol.39
, pp. 645-654
-
-
Schulze-Bergkamen, H.1
Brenner, D.2
Krueger, A.3
-
135
-
-
0032055940
-
A20 inhibits NF-κB activation in endothelial cells without sensitizing to TNF-mediated apoptosis
-
Ferran, C., Stroka, D. M., Badrichani, A. Z. et al. (1998) A20 inhibits NF-κB activation in endothelial cells without sensitizing to TNF-mediated apoptosis. Blood 91, 2249-2258
-
(1998)
Blood
, vol.91
, pp. 2249-2258
-
-
Ferran, C.1
Stroka, D.M.2
Badrichani, A.Z.3
-
136
-
-
0035076884
-
Overexpression of A20 in endothelial cells of vascularized Grafts creates a protective barrier against TNF and FAS-mediated apoptosis
-
Daniel, S., Arvelo, M. B. and Ferran, C. (2001) Overexpression of A20 in endothelial cells of vascularized Grafts creates a protective barrier against TNF and FAS-mediated apoptosis. Transpl. Proc. 33, 225
-
(2001)
Transpl. Proc.
, vol.33
, pp. 225
-
-
Daniel, S.1
Arvelo, M.B.2
Ferran, C.3
-
137
-
-
0036189282
-
A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis
-
Arvelo, M. B., Cooper, J. T., Longo, C. et al. (2002) A20 protects mice from D-galactosamine/lipopolysaccharide acute toxic lethal hepatitis. Hepatology 35, 535-543
-
(2002)
Hepatology
, vol.35
, pp. 535-543
-
-
Arvelo, M.B.1
Cooper, J.T.2
Longo, C.3
-
138
-
-
0033709907
-
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
-
Zheng, T. S., Hunot, S., Kuida, K. et al. (2000) Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nat. Med. 6, 1241-1247
-
(2000)
Nat. Med.
, vol.6
, pp. 1241-1247
-
-
Zheng, T.S.1
Hunot, S.2
Kuida, K.3
-
139
-
-
0037386245
-
Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2
-
Cauwels, A., Janssen, B., Waeytens, A., Cuvelier, C. and Brouckaert, P. (2003) Caspase inhibition causes hyperacute tumor necrosis factor-induced shock via oxidative stress and phospholipase A2. Nat. Immunol. 4, 387-393
-
(2003)
Nat. Immunol.
, vol.4
, pp. 387-393
-
-
Cauwels, A.1
Janssen, B.2
Waeytens, A.3
Cuvelier, C.4
Brouckaert, P.5
-
140
-
-
0033579422
-
Resistance to the cytotoxic effects of tumor necrosis factor α can be overcome by inhibition of a FADD/caspase-dependent signaling pathway
-
Khwaja, A. and Tatton, L. (1999) Resistance to the cytotoxic effects of tumor necrosis factor α can be overcome by inhibition of a FADD/caspase-dependent signaling pathway. J. Biol. Chem. 274, 36817-36823
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 36817-36823
-
-
Khwaja, A.1
Tatton, L.2
-
141
-
-
0032962588
-
Apoptosis and therapy
-
Schmitt, C. A. and Lowe, S. W. (1999) Apoptosis and therapy. J. Pathol. 187, 127-137
-
(1999)
J. Pathol.
, vol.187
, pp. 127-137
-
-
Schmitt, C.A.1
Lowe, S.W.2
-
142
-
-
3042674026
-
Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma
-
Shiraki, K., Sugimoto, K., Yamanaka, Y. et al. (2003) Overexpression of X-linked inhibitor of apoptosis in human hepatocellular carcinoma. Int. J. Mol. Med. 12, 705-708
-
(2003)
Int. J. Mol. Med.
, vol.12
, pp. 705-708
-
-
Shiraki, K.1
Sugimoto, K.2
Yamanaka, Y.3
-
143
-
-
0037310476
-
Bcl-2 prevents doxorubicin-induced apoptosis of human liver cancer cells
-
Takahashi, M., Saito, H., Atsukawa, K., Ebinuma, H., Okuyama, T. and Ishii, H. (2003) Bcl-2 prevents doxorubicin-induced apoptosis of human liver cancer cells. Hepatol. Res. 25, 192-201
-
(2003)
Hepatol. Res.
, vol.25
, pp. 192-201
-
-
Takahashi, M.1
Saito, H.2
Atsukawa, K.3
Ebinuma, H.4
Okuyama, T.5
Ishii, H.6
-
144
-
-
0037380281
-
Expression of Bcl-2 family modulated through p53-dependent pathway in human hepatocellular carcinoma
-
Chiu, C. T., Yeh, T. S., Hsu, J. C. and Chen, M. F. (2003) Expression of Bcl-2 family modulated through p53-dependent pathway in human hepatocellular carcinoma. Dig. Dis. Sci. 48, 670-676
-
(2003)
Dig. Dis. Sci.
, vol.48
, pp. 670-676
-
-
Chiu, C.T.1
Yeh, T.S.2
Hsu, J.C.3
Chen, M.F.4
-
145
-
-
0029815941
-
Bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity
-
D'Sa-Eipper, C., Subramanian, T. and Chinnadurai, G. (1996) Bfl-1, a bcl-2 homologue, suppresses p53-induced apoptosis and exhibits potent cooperative transforming activity. Cancer Res. 56, 3879-3882
-
(1996)
Cancer Res.
, vol.56
, pp. 3879-3882
-
-
D'Sa-Eipper, C.1
Subramanian, T.2
Chinnadurai, G.3
-
146
-
-
0036195196
-
AKT proto-oncogene overexpression is an early event during sporadic colon carcinogensis
-
Roy, H. K., Olusola, B. F., Clemens, D. L. et al. (2002) AKT proto-oncogene overexpression is an early event during sporadic colon carcinogensis. Carcinogenesis 23, 201-205
-
(2002)
Carcinogenesis
, vol.23
, pp. 201-205
-
-
Roy, H.K.1
Olusola, B.F.2
Clemens, D.L.3
|