메뉴 건너뛰기




Volumn 278, Issue 3 47-3, 2000, Pages

The IκB/NF-κB system: A key determinant of mucosal inflammation and protection

Author keywords

Bacteria; Cytokines; Gene manipulation; Intestinal epithelial cells; Signal transduction

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

EID: 17544365995     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.278.3.c451     Document Type: Review
Times cited : (364)

References (16)
  • 1
    • 0030783897 scopus 로고    scopus 로고
    • The significance and potential molecular mechanisms of gastrointestinal barrier homeostasis
    • Andersson, R., X. Wang, and V. Soltesz. The significance and potential molecular mechanisms of gastrointestinal barrier homeostasis. Scand. J. Gastroenterol. 32: 1073-1082, 1997.
    • (1997) Scand. J. Gastroenterol. , vol.32 , pp. 1073-1082
    • Andersson, R.1    Wang, X.2    Soltesz, V.3
  • 2
    • 0027526976 scopus 로고
    • Differential cytokine regulation of complement C3, C4 and factor B synthesis in human intestinal epithelial cell line, Caco-2
    • Andoh, A., Y. Fujiyama, and S. Hosoda. Differential cytokine regulation of complement C3, C4 and factor B synthesis in human intestinal epithelial cell line, Caco-2. J. Immunol. 151: 4239-4247, 1993.
    • (1993) J. Immunol. , vol.151 , pp. 4239-4247
    • Andoh, A.1    Fujiyama, Y.2    Hosoda, S.3
  • 4
    • 0028967819 scopus 로고
    • Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB
    • Arenzana-Seisdedos, F., J. Thompson, M. S. Rodriguez, F. Bachelerie, D. Thomas, and R. T. Hay. Inducible nuclear expression of newly synthesized IκBα negatively regulates DNA-binding and transcriptional activities of NF-κB. Mol. Cell. Biol. 15: 2689-2696, 1995.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2689-2696
    • Arenzana-Seisdedos, F.1    Thompson, J.2    Rodriguez, M.S.3    Bachelerie, F.4    Thomas, D.5    Hay, R.T.6
  • 5
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi, A., and V. M. Dixit. Death receptors: signaling and modulation. Science 281: 1305-1308, 1998.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 6
    • 0032217267 scopus 로고    scopus 로고
    • IκB-NF-κB structures: At the interface of inflammation control
    • Baeuerle, P. A. IκB-NF-κB structures: at the interface of inflammation control. Cell 95: 729-731, 1998.
    • (1998) Cell , vol.95 , pp. 729-731
    • Baeuerle, P.A.1
  • 7
    • 0028174061 scopus 로고
    • Function and activation of NF-κB in the immune system
    • Baeuerle, P. A., and T. Henkle. Function and activation of NF-κB in the immune system. Annu. Rev. Immunol. 12: 141-179, 1994.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 141-179
    • Baeuerle, P.A.1    Henkle, T.2
  • 8
    • 0026527184 scopus 로고
    • The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression
    • Ballard, D. W., E. P. Dixon, N. J. Peffer, H. Bogerd, S. Doerre, B. Stein, and W. C. Greene. The 65-kDa subunit of human NF-κB functions as a potent transcriptional activator and a target for v-Rel-mediated repression. Proc. Natl. Acad. Sci. USA 89: 1875-1879, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1875-1879
    • Ballard, D.W.1    Dixon, E.P.2    Peffer, N.J.3    Bogerd, H.4    Doerre, S.5    Stein, B.6    Greene, W.C.7
  • 9
    • 0028607055 scopus 로고
    • Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice
    • Baribault, H., J. Penner, R. V. Iozzo, and M. Wilson-Heiner. Colorectal hyperplasia and inflammation in keratin 8-deficient FVB/N mice. Genes Dev. 8: 2964-2973, 1994.
    • (1994) Genes Dev. , vol.8 , pp. 2964-2973
    • Baribault, H.1    Penner, J.2    Iozzo, R.V.3    Wilson-Heiner, M.4
  • 10
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-κB, a pivotal transcription factor in chronic inflammatory diseases
    • Barnes, P. J., and M. Karin. Nuclear factor-κB, a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336: 1066-1071, 1997.
    • (1997) N. Engl. J. Med. , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 11
    • 0027332498 scopus 로고
    • The IκB protein: Multifunctional regulators of Rel/NF-κB transcription factors
    • Beg, A. A., and A. S. Baldwin. The IκB protein: multifunctional regulators of Rel/NF-κB transcription factors. Genes Dev. 7: 2064-2070, 1993.
    • (1993) Genes Dev. , vol.7 , pp. 2064-2070
    • Beg, A.A.1    Baldwin, A.S.2
  • 12
    • 0031437893 scopus 로고    scopus 로고
    • Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit
    • Bird, T. A., K. Schooley, S. K. Dower, H. Hagen, and G. D. Virca. Activation of nuclear transcription factor NF-κB by interleukin-1 is accompanied by casein kinase II-mediated phosphorylation of the p65 subunit. J. Biol. Chem. 272: 32606-32612, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 32606-32612
    • Bird, T.A.1    Schooley, K.2    Dower, S.K.3    Hagen, H.4    Virca, G.D.5
  • 14
    • 0039179478 scopus 로고    scopus 로고
    • Cellular differentiation causes a selective down-regulation of IL-1β-mediated NF-κB activation and IL-8 gene expression in intestinal epithelial cells
    • In press
    • Bocker, U., A. J. G. Schottelius, J. Watson, L. Holt, L. L. Licato, D. A. Brenner, R. B. Sartor, and C. Jobin. Cellular differentiation causes a selective down-regulation of IL-1β-mediated NF-κB activation and IL-8 gene expression in intestinal epithelial cells. J. Biol. Chem. In press.
    • J. Biol. Chem.
    • Bocker, U.1    Schottelius, A.J.G.2    Watson, J.3    Holt, L.4    Licato, L.L.5    Brenner, D.A.6    Sartor, R.B.7    Jobin, C.8
  • 15
    • 0028117098 scopus 로고
    • Modulation of epithelial cell growth by intraepithelial αδ T cells
    • Boismenu, R., and W. L. Havran. Modulation of epithelial cell growth by intraepithelial αδ T cells. Science 266: 1253-1255, 1994.
    • (1994) Science , vol.266 , pp. 1253-1255
    • Boismenu, R.1    Havran, W.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.