Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat

Gastroenterology

Volumn 114, Issue 1, 1998, Pages 164-174

  Sokol, R J ^a   McKim J M , Jr ^a   Goff, M C ^a   Ruyle, S Z ^a   Devereaux, M W ^a   Han, D ^a   Packer, L ^a   Everson, G ^a  

^a CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA TOCOPHEROL; ASPARTATE AMINOTRANSFERASE; BILE ACID; TAUROCHENODEOXYCHOLIC ACID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTASIS; CONTROLLED STUDY; ENZYME BLOOD LEVEL; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; LIPID PEROXIDATION; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RAT; VITAMIN INTAKE;

EID: 0031983188     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70644-4     Document Type: Article

References (59)

1. RO Ramirez RJ Sokol Medical management of cholestasis FJ Suchy Liver disease in children 1994 Mosby St. Louis, MO 356 388
2. PF Whitington WF Balistreri Liver transplantation in pediatrics: indications, contraindications, and pretransplant management J Pediatr 118 1991 169 177
3. TE Starzl AJ Demetris D Van Thiel Liver transplantation N Engl J Med 321 1989 1014 1022
4. UNOS Update 11 1995 37 41
5. H Greim P Dzygan F Schaffner H Popper Determination of bile acids in needle biopsies of human liver Biochem Med 8 1973 280 286
6. AF Attili M Angelico A Cantafora D Alvaro L Capocaccia Bile acid–induced liver toxicity: relation to the hydrophobic-hydrophilic balance of bile acids Med Hypotheses 19 1986 57 69
7. AF Hofmann H Popper Ursodeoxycholic acid for primary biliary cirrhosis Lancet 2 1987 398 399
8. S Shefer FG Zaki G Salen Early morphologic and enzymatic changes in livers of rats treated with chenodeoxycholic and ursodeoxycholic acids Hepatology 3 1983 201 208
9. DC Fisher NS Cooper MA Trothschild EH Mosbach Effect of dietary chenodeoxycholic acid and lithocholic acid in the rabbit Am J Dig Dis 19 1974 877 886
10. KP Morrissey CK McSherry RL Swarm WH Nieman JE Deitrick Toxicity of chenodeoxycholic acid in the non human primate Surgery 77 1975 851 860
11. JM Phillips RL Fisher DW Anderson SP Lan JM Lachin JL Boyer The Steering Committee for the National Cooperative Gallstone Study Group Ultrastructural evidence of intrahepatic cholestasis before and after chenodeoxycholic acid therapy in patients with cholelithiasis: the National Cooperative Gallstone Study Hepatology 3 1983 209 220
12. LJ Schoenfield JM Lachin The Steering Committee and the National Cooperative Gallstone Study Group Chenodiol (chenode-oxycholic acid) for dissolution of gallstones: the national cooperative study: a controlled trial of efficacy and safety Ann Intern Med 95 1981 257 282
13. PR Galle L Theilmann R Raedsch G Otto A Stiehl Ursodeoxycholate reduces hepatotoxicity of bile salts in primary human hepatocytes Hepatology 12 1990 486 491
14. RE Poupon R Poupon B Blakau the UDCA-PBC Study Group Ursodiol for the long-term treatment of primary biliary cirrhosis N Engl J Med 330 1994 1342 1347
15. A Stiehl G Rudolph R Raedsch B Moller U Hopf E Lotterer J Bircher U Folsch J Klaus R Endete M Senn Ursodeoxycholic acid–induced changes of plasma and urinary bile acids in patients with primary biliary cirrhosis Hepatology 12 1990 492 497
16. DM Heuman AS Mills J McCall PB Hylemon WM Pandak ZR Vlahcevic Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts Gastroenterology 100 1991 203 211
17. AK Batta R Arora G Salen S Tint D Eskreis S Katz Characterization of serum and urinary bile acids in patients with primary biliary cirrhosis by gas-liquid chromatography–mass spectrometry: effect of ursodeoxycholic acid treatment J Lipid Res 30 1989 1953 1962
18. P Marteau O Chazouilleres A Myara R Jian J-C Rambaud R Poupon Effect of chronic administration of ursodeoxycholic acid on the ileal absorption of endogenous bile acids in man Hepatology 12 1991 1206 1208
19. J Scholmerich MS Becher K Schmidt R Schubert B Kremer S Feldhaus W Gerok Influence of hydroxylation and conjugation of bile acids on their membrane-damaging properties—studies on isolated hepatocytes and membrane vesicles Hepatology 4 1984 661 666
20. D Heuman WM Pandak PB Hylemon ZR Vlahcevic Conjugates of ursodeoxycholate protect against cytotoxicity of more hydropho-bic bile salts: in vitro studies in rat hepatocytes and human erythrocytes Hepatology 14 1991 920 926
21. MJ Lee MW Whitehouse Inhibition of electron transport and coupled phosphorylation in liver mitochondria by cholanic (bile) acids and their conjugates Biochim Biophys Acta 100 1965 317 328
22. S Krahenbuhl C Talos S Fischer J Reichen Toxicity of bile acids on the electron transport chain of isolated rat liver mitochondria Hepatology 19 1994 471 479
23. R Botla JR Spivey HI Aguilar SF Bronk GJ Gores Ursodeoxycho-late (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection J Pharmacol Exp Ther 272 1995 930 938
24. RJ Sokol BM Winklhofer-Roob MW Devereaux JM McKim Jr Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids Gastro-enterology 109 1995 1249 1256
25. JR Spivey SF Bronk GJ Gores Glycochenodeoxycholate-induced lethal hepatocellular injury in rat hepatocytes. Role of ATP depletion and cytosolic free calcium J Clin Invest 92 1993 17 24
26. RJ Sokol M Devereaux R Khandwala Effect of dietary lipid and vitamin E on mitochondrial lipid peroxidation and hepatic injury in the bile duct–ligated rat J Lipid Res 32 1991 1349 1357
27. RJ Sokol M Devereaux R Khandwala K O'Brien Evidence for involvement of oxygen free radicals in bile acid toxicity to isolated rat hepatocytes Hepatology 17 1993 869 881
28. GT Everson BP Daggy C McKinley JA Story Effects of psyllium hydrophilic mucilloid on LDL-cholesterol and bile acid synthesis in hypercholesterolemic man J Lipid Res 33 1992 1183 1192
29. S Krahenbuhl C Talos BH Lauterburg J Reichen Reduced antioxidative capacity in liver mitochondria from bile duct ligated rats Hepatology 22 1995 607 612
30. RJ Sokol MW Devereaux K O'Brien RA Khandwala JP Loehr Abnormal hepatic mitochondrial respiration and cytochrome c oxidase activity in rats with long-term copper overload Gastroen-terology 105 1993 178 187
31. J Loewenstein HR Scholte EM Wit-Peeters A rapid and simple procedure to deplete rat liver mitochondria of lysosomal activity Biochim Biophys Acta 223 1970 432 436
32. OH Lowry NJ Rosebrough AL Farr RJ Randall Protein measurement with the Folin phenol reagent J Biol Chem 193 1951 265 275
33. RO Recknagel AK Ghoshal Quantitative estimation of peroxidative decomposition of rat liver microsomal and mitochondrial lipids after carbon tetrachloride poisoning Exp Mol Pathol 5 1965 413 426
34. BR Bacon AS Tavill GM Brittenham CH Park RO Recknagel Hepatic lipid peroxidation in vivo in rats with chronic iron overload J Clin Invest 71 1983 429 439
35. SP Chiang CF Gessert OH Lowry Calorimetric determination of extracted lipids. Research Report 1957 Air University School of Aviation Medicine, United States Air Force Texas 56 113
36. JG Bieri TJ Tolliver GL Catignani Simultaneous determination of alpha tocopherol and retinol in plasma or red cells by high pressure liquid chromatography Am J Clin Nutr 32 1979 2143 2149
37. N Zoellner K Kirsch A micromethod for lipids using a sulphooxanillin reaction Z Gesamte Exp Med 135 1962 545 561
38. RJ Sokol JE Heubi ST Iannaccone KE Bove WF Balistreri Vitamin E deficiency with normal serum vitamin E concentrations in children with chronic cholestasis N Engl J Med 310 1984 1209 1212
39. JK Lang K Gohil L Packer Simultaneous determination of tocopherols, ubiquinols, and ubiquinones in blood, plasma, tissue homogenates and subcellular fractions Anal Biochem 157 1986 106 116
40. DL Schmucker M Ohta S Kanai Y Sato K Kitani Hepatic injury induced by bile salts: correlation between biochemical and morphological events Hepatology 12 1990 1216 1221
41. AL Tappel Vitamin E as the biological antioxidant Vitam Horm 20 1962 493 510
42. MG Traber W Cohn DPR Muller Absorption, transport and delivery to tissues L Packer J Fuchs Vitamin E in health and disease 1993 Dekker New York 35 52
43. PJ Winwood MJP Arthur Kupffer cells: their activation and role in animal models of liver injury and human liver disease Semin Liv Dis 13 1993 50 59
44. H Jaeschke A Farhood Neutrophil and Kupffer cell–induced oxidant stress and ischemia-reperfusion injury in rat liver Am J Physiol 260 1991 G355 G362
45. RJ Sokol MW Devereaux R Khandwala Xanthine oxidase inhibition reduces cholestatic liver injury in the bile duct–ligated rat model without affecting hepatocyte lipid peroxidation (abstr) Hepatology 22 1995 317A
46. C Garcia-Ruiz A Colell A Morales N Kaplowitz JC Fernandez-Checa Role of oxidative stress generated from the mitochondrial electron transport chain and mitochondrial glutathione status in loss of mitochondrial function and activation of transcription factor nuclear factor-kβ: studies with isolated mitochondria and rat hepatocytes Molec Pharmacol 48 1995 825 834
47. TL Dawson GJ Gores A-L Nieminen B Herman JJ Lemasters Mitochondria as a source of reactive oxygen species during reductive stress in rat hepatocytes Am J Physiol 264 1993 C961 C967
48. JF Turrens A Boveris Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria Biochem J 191 1980 421 427
49. RE Beyer The participation of coenzyme Q in free radical production and antioxidation Free Radic Biol Med 8 1990 545 565
50. BG Rosser GJ Gores Liver cell necrosis: cellular mechanisms and clinical implications Gastroenterology 108 1995 252 275
51. R Imberti A-L Nieminen B Herman JJ Lemasters Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t -butyl hydroperoxide: protection by fructose, cyclosporin A and trifluo-perazine J Pharmacol Exp Ther 265 1993 392 400
52. A-L Nieminen AK Saylor SA Tesfai B Herman JJ Lemasters Contribution of the mitochondrial permeability transition to lethal injury after exposure of hepatocytes to t -butylhydroperoxide Biochem J 307 1995 99 106
53. 2+ is dependent on mitochondrial-generated reactive oxygen species FEBS Lett 378 1996 150 152
54. MS Straka MW Devereaux RJ Sokol Evidence for oxidant stress in the mitochondrial membrane permeability transition induced by glycochenodeoxycholic acid (abstr) Hepatology 24 1996 237A
55. T Patel SF Bronk GJ Gores Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes J Clin Invest 94 1994 2183 2192
56. T Patel GJ Gores Inhibition of bile-salt–induced hepatocyte apoptosis by the antioxidant lazaroid U83836E Toxicol Appl Pharmacol 142 1997 116 122
57. A Celli FG Que K Shogren GJ Gores NF LaRusso Glutathione depletion in human chalangiocytes is associated with diminished Bcl-2 expression and a decreased apoptotic threshold (abstr) Gastroenterology 112 1997 A1238
58. J Yang L Xuesong K Bhalla CN Kim AM Ibrado J Cai T-I Peng DP Jones X Wang Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked Science 275 1997 1129 1132
59. RM Kluck E Bossy-Wetzel DR Green DD Newmeyer The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis Science 275 1997 1132 1136