Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria

Cancer Research

Volumn 63, Issue 7, 2003, Pages 1483-1489

  Yamaguchi, Hirohito ^a,b   Bhalla, Kapil ^a,b   Wang, Hong Gang ^a,b  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); ALOXISTATIN; ANTIGEN P24; APOPTOSIS INDUCING FACTOR; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CALPASTATIN; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CELL RECEPTOR; CYTOCHROME C; DEATH RECEPTOR 5; PROTEIN BAX; PROTEIN BID; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE OMI; THAPSIGARGIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL FRACTIONATION; COLON CANCER; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALPAIN; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; COLONIC NEOPLASMS; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; THAPSIGARGIN; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037380884     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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