Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor α toxicity

Gastroenterology

Volumn 115, Issue 5, 1998, Pages 1229-1237

  Xu, Y ^a   Jones, B E ^a   Neufeld, D S ^a   Czaja, M J ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; BUTHIONINE SULFOXIMINE; DACTINOMYCIN; GALACTOSAMINE; GLUTATHIONE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MALEIC ACID DIETHYL ESTER; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; LIVER CELL; LIVER INJURY; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031763795     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70095-2     Document Type: Article

References (49)

1. MJ Czaja KC Flanders L Biempica C Klein MA Zern FR Weiner Expression of tumor necrosis factor-α and transforming growth factor-β1 in acute rat liver injury Growth Factors 1 1989 219 226
2. F Kayama T Yoshida MR Elwell MI Luster Role of tumor necrosis factor-α in cadmium-induced hepatotoxicity Toxicol Appl Pharmacol 131 1995 224 234
3. ME Blazka JL Wilmer SD Holladay RE Wilson MI Luster Role of proinflammatory cytokines in acetaminophen hepatotoxicity Toxicol Appl Pharmacol 133 1995 43 52
4. MJ Czaja FR Weiner KC Flanders MA Giambrone R Wind L Biempica MA Zern The in vitro and in vivo association of transforming growth factor-β with hepatic fibrosis J Cell Biol 108 1989 2477 2482
5. CJ McClain DA Cohen Increased tumor necrosis factor production by monocytes in alcoholic hepatitis Hepatology 9 1989 349 351
6. K Yoshioka S Kakumu M Arao Y Tsutsumi M Inoue Tumor necrosis factor-α production by peripheral blood mononuclear cells of patients with chronic liver disease Hepatology 10 1989 769 773
7. I Hishinuma JI Nagakawa K Hirota K Miyamoto K Tsukidate T Yamanaka KI Katayama I Yamatsu Involvement of tumor necrosis factor-α in development of hepatic injury in galactosamine-sensitized mice Hepatology 12 1990 1187 1191
8. MJ Czaja J Xu E Alt Prevention of carbon tetrachloride-induced rat liver injury by soluble tumor necrosis factor receptor Gastroenterology 108 1995 1849 1854
9. JW Larrick SC Wright Cytotoxic mechanism of tumor necrosis factor-α FASEB J 4 1990 3215 3223
10. RJ Zimmerman A Chan SA Leadon Oxidative damage in murine tumor cells treated in vitro by recombinant tumor necrosis factor Cancer Res 49 1989 1644 1648
11. K Schulze-Osthoff AC Bakker B Vanhaesebroeck R Beyaert WA Jacob W Fiers Cytotoxic activity of tumor necrosis factor is mediated by early damage of mitochondrial functions J Biol Chem 267 1992 5317 5323
12. FC Kull P Cuatrecasas Possible requirement of internalization in the mechanism of in vitro cytotoxicity in tumor necrosis serum Cancer Res 41 1981 4885 4890
13. GHW Wong JH Elwell LW Oberley DV Goeddel Manganous superoxide dismutase is essential for cellular resistance to cytotoxicity of tumor necrosis factor Cell 58 1989 923 931
14. MJ Czaja ML Schilsky Y Xu P Schmiedeberg A Compton L Ridnour LW Oberley The induction of MnSOD gene expression in a hepatic model of TNF-α toxicity does not result in increased protein Am J Physiol 266 1994 G737 G744
15. 2 tolerance Am J Physiol 263 1992 L22 L26
16. RJ Zimmerman BJ Marafino Jr A Chan P Landre JL Winkelhake The role of oxidant injury in tumor cell sensitivity to recombinant human tumor necrosis factor in vivo J Immunol 142 1989 1405 1409
17. 2 J Clin Invest 89 1992 794 802
18. V Goossens J Grooten K De Vos W Fiers Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity Proc Natl Acad Sci USA 92 1995 8115 8119
19. GM Adamson RE Billings Tumor necrosis factor induced oxidative stress in isolated mouse hepatocytes Arch Biochem Biophys 294 1992 223 229
20. RK Singhal ME Anderson A Meister Glutathione, a first line of defense against cadmium toxicity FASEB J 1 1987 220 223
21. JY Chou Temperature-sensitive adult liver cell line dependent on glucocorticoid for differentiation Mol Cell Biol 3 1983 1013 1020
22. MN Berry BS Friend High-yield preparation of isolated rat liver parenchymal cells: a biochemical and fine structure study J Cell Biol 43 1969 506 520
23. HL Leffert KS Koch T Moran M Williams Liver cells Methods Enzymol 58 1979 536 544
24. F Denizat R Lang Rapid colorimetric assay for cell growth and survival J Immunol Methods 89 1986 271 277
25. J Xu Y Xu Q Nguyen PM Novikoff MJ Czaja Induction of hepatoma cell apoptosis by c-myc requires zinc and occurs in the absence of DNA fragmentation Am J Physiol 270 1996 G60 G70
26. ME Anderson Tissue glutathione RA Greenwald CRC handbook of methods for oxygen radical research 1985 CRC Press Boca Raton, FL 317 323
27. E Schreiber P Matthias MM Muller W Schaffner Rapid detection of octamer binding proteins with “mini-extracts” prepared from a small number of cells Nucleic Acids Res 17 1989 6419
28. R Cathcart E Schwiers BN Ames Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay Anal Biochem 134 1983 111 116
29. AR Rosenkranz S Schmaldienst KM Stuhlmeier W Chen W Knapp GJ Zlabinger A microplate assay for the detection of oxidative products using 2,'7,'-dichlorofluorescein-diacetate J Immunol Methods 156 1992 39 45
30. AM Diehl DC Johns SQ Yang HZ Lin M Yin LA Matelis JH Lawrence Adenovirus-mediated transfer of CCAAT/enhancer-binding protein-α identifies a dominant antiproliferative role for this isoform in hepatocytes J Biol Chem 271 1996 7343 7350
31. RA Heller M Kronke Tumor necrosis factor receptor-mediated signaling pathways J Cell Biol 126 1994 5 9
32. PA Amstad G Krupitza PA Cerutti Mechanism of c-fos induction by active oxygen Cancer Res 52 1992 3952 3960
33. R Schneck P Rieber PA Baeuerle Reactive oxygen intermediates as apparently widely used messengers in the activation of NF-κB transcription factor and HIV-1 EMBO J 10 1991 2247 2258
34. M Leist F Gantner S Jilg A Wendel Activation of the 55 kDa TNF receptor is necessary and sufficient for TNF-induced liver failure, hepatocyte apoptosis, and nitrite release J Immunol 154 1995 1307 1316
35. ME Anderson F Prowrie RN Puri A Meister Glutathione monoethyl ester: preparation, uptake by tissues, and conversion to glutathione Arch Biochem Biophys 239 1985 538 548
36. VJ Palombella J Vilcek Mitogenic and cytotoxic actions of tumor necrosis factor in BALB/c 3T3 cells J Biol Chem 264 1989 18128 18136
37. P Akerman P Cote SQ Yang C McClain S Nelson GJ Bagby AM Diehl Antibodies to tumor necrosis factor-α inhibit liver regeneration after partial hepatectomy Am J Physiol 263 1992 G579 G585
38. A Morales C Garcia-Ruiz M Miranda M Mari A Colell E Ardite JC Fernandez-Checa Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase J Biol Chem 272 1997 30371 30379
39. J Arias-Diaz E Vara C Garcia N Villa JM Rodriquez P Ortiz JL Balibrea S -Adenosylmethionine protects hepatocytes against the effects of cytokines J Surg Res 62 1996 79 84
40. T Chiba S Takahashi N Sato S Ishii K Kikuchi Fas-mediated apoptosis is modulated by intracellular glutathione in human T cells Eur J Immunol 26 1996 1164 1169
41. Y Xu MJ Czaja Glutathione (GSH) depletion sensitizes liver cells to TNF-α cytotoxicity (abstr) Hepatology 24 1996 186A
42. K-I Lin S-H Lee R Narayanan JM Baraban JM Hardwick RR Ratan Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B J Cell Biol 131 1995 1149 1161
43. RS Fernandes TG Coter Apoptosis or necrosis: intracellular levels of glutathione influence mode of cell death Biochem Pharmacol 48 1994 675 681
44. ES Levine HS Friedman OW Griffith OM Colvin JH Raynor M Lieberman Cardiac cell toxicity induced by 4-hydroperoxycyclophosphamide is modulated by glutathione Cardivasc Res 27 1993 1248 1253
45. JC Fernandez-Checa C Garcia-Ruiz M Ookhtens N Kaplowitz Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats J Clin Invest 87 1991 397 405
46. JC Fernandez-Checa N Kaplowitz C Garcia-Ruiz A Colell M Miranda M Mari E Ardite A Morales GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect Am J Physiol 273 1997 G7 G17
47. A Colell C Garcia-Ruiz M Mari M Miranda E Ardite J Rodes N Kaplowitz JC Fernandez-Checa Chronic ethanol feeding sensitizes rat hepatocytes to TNF-induced cytotoxicity, oxidative stress and NF-κB activation (abstr) Hepatology 24 1996 193A
48. B Liu YA Hannun Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione J Biol Chem 272 1997 16281 16287
49. C Garcia-Ruiz A Colell M Mari A Morales JC Fernandez-Checa Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species J Biol Chem 272 1997 11369 11377