Subcellular localization of photofrin® determines the death phenotype of human epidermoid carcinoma A431 cells triggered by photodynamic therapy: When plasma membranes are the main targets

Journal of Cellular Physiology

Volumn 194, Issue 3, 2003, Pages 363-375

  Hsieh, Ya Ju ^a   Wu, Chih Ching ^a   Chang, Cheng Jen ^b   Yu, Jau Song ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; DNA FRAGMENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; P21 ACTIVATED KINASE 2; PHOSPHATIDYLSERINE; PHOTOFRIN; PROTEIN KINASE; PROTEIN P21; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL MEMBRANE; CELL PROLIFERATION; CELL SWELLING; CONTROLLED STUDY; ENZYME ACTIVATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; IN VIVO STUDY; MEMBRANE DAMAGE; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA;

ANTINEOPLASTIC AGENTS; CARCINOMA, SQUAMOUS CELL; CASPASE 3; CASPASES; CELL DEATH; CELL MEMBRANE; CELL SIZE; DIHEMATOPORPHYRIN ETHER; DNA FRAGMENTATION; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LASERS; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; PHENOTYPE; PHOSPHATIDYLSERINES; PHOTOCHEMOTHERAPY; POLY(ADP-RIBOSE) POLYMERASES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 0037362431     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.10273     Document Type: Article

References (52)

1. Agarwal ML, Clay ME, Harvey WJ, Evans HH, Antunez AR, Oleinick NL. 1991. Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells. Cancer Res 51:5993-5996.
2. Agarwal ML, Larkin HE, Zaidi SI, Mukhtar H, Oleinick NL. 1993. Phospholipase activation triggers apoptosis in photosensitized mouse lymphoma cells. Cancer Res 53:5897-5902.
3. Assefa Z, Vantieghem A, Declercq W, Vandenabeele P, Vandenheede JR, Merlevede W, Witte PD, Agostinis P. 1999. The activation of the c-jun N-terminal kinase and p38 mitogen-activated protein kinase signaling pathways protects HeLa cells from apoptosis following photodynamic therapy with hypericin. J Biol Chem 274:8788-8796.
4. Bennett BL, Sasaki DT, Murray BW, O'Leary EC, Sakata ST, Xu W, Leisten JC, Motiwala A, Pierce S, Satoh Y, Bhagwat SS, Manning AM, Anderson DW. 2001. SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase. Proc Natl Acad Sci USA 98:13681-13686.
5. Bertrand R, Solary E, O'Connor P, Kohn KW, Pommier Y. 1994. Induction of a common pathway of apoptosis by staurosporine. Exp Cell Res 211:314-321.
6. Buettner GR, Kelley EE, Burns CP. 1993. Membrane lipid free radicals produced from L1210 murine leukemia cells by photofrin photosensitization: An electron paramagnetic resonance spin trapping study. Cancer Res 53:3670-3673.
7. Chan W-H, Yu J-S, Yang S-D. 2000. Apoptotic signaling cascade in photosensitized human epidermal carcinoma A431 cells: Involvement of singlet oxygen, c-Jun N-terminal kinase, caspase-3 and p21-activated kinase 2. Biochem J 351:221-232.
8. Dellinger M. 1996. Apoptosis or necrosis following Photofrin photosensitization: Influence of the incubation protocol. Photochem Photobiol 64:182-187.
9. Denecker G, Vercammen D, Decleraq W, Vandenabeele P. 2001. Apoptotic and necrotic cell death induced by death domain receptors. Cell Mol Life Sci 58:356-370.
10. Dougherty TJ. 1996. A brief history of clinical photodynamic therapy development at Rosewell Park Cancer Institute. J Clin Laser Med 14:219-221.
11. Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, Moan J, Peng Q. 1998. Photodynamic therapy. J Natl Cancer Inst 90:889-905.
12. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. 1998. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391:43-50.
13. Engbrecht BW, Menon C, Kachur AV, Hahn SM, Fraker DL. 1999. Photofrin-mediated photodynamic therapy induces vascular occlusion and apoptosis in a human sarcoma xenograft model. Cancer Res 59:4334-4342.
14. Fabris C, Valduga G, Miotto G, Borsetto L, Jori G, Garbisa S, Reddi E. 2001. Photosensitization with zinc (II) phthalocyanine as a switch in the decision between apoptosis and necrosis. Cancer Res 61:7495-7500.
15. Formigli L, Papucci L, Tani A, Schiavone N, Tempestini A, Orlandini GE, Capaccioli S, Orlandini SZ. 2000. Aponecrosis: Morphological and biochemical exploration of a syncretic process of cell death sharing apoptosis and necrosis. J Cell Physiol 182:41-49.
16. 2+-ATPase in R3230AC mammary adenocarcinomas. Cancer Res 48:3360-3366.
17. Girotti A. 1990. Photosensitized lipid peroxidation in biological membranes. In: Kessel D, editor. Photodynamic therapy of neoplastic disease, Vol 1. Florida: CRC Press. p 229-245.
18. Halliwell B, Gutteridge JMC. 1989. Free radicals in biology and medicine. New York: Oxford University Press. 936 p.
19. He X-Y, Sikes S, Thomsen L, Chung LWK, Jacques SL. 1994. Photodynamic therapy with photofrin II induces programmed cell death in carcinoma cell lines. Photochem Photobiol 59:468-473.
20. He J, Whitacre CM, Xue LY, Beger NA, Oleinick NL. 1998. Protease activation and cleavage of poly(ADP-ribose) polymerase: An integral part of apoptosis in response to photodynamic therapy. Cancer Res 58:940-946.
21. Henderson BW, Dougherty TJ, 1992. How does photodynamic therapy work? Photochem Photobiol 55:145-157.
22. Hirsch T, Marchetti P, Susin SA, Dallaporta B, Zamzami N, Marzo I, Geuskens M, Kroemer G. 1997. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 15:1573-1581.
23. Johnson BE, Ferguson J. 1990. Drug and chemical photosensitivity. Semin Dermatol 9:39-46.
24. Johnson LV, Walsh ML, Bockus BJ, Chen LB. 1981. Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy. J Cell Biol 88:526-535.
25. Kessel D, Luo Y, Deng Y, Chang CK. 1997. The role of subcellular localization in initiation of apoptosis by photodynamic therapy. Photochem Photobiol 65:422-426.
26. Klotz LO, Fritsch C, Briviba K, Tsacmacidis N, Schliess F, Sies H. 1998. Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy. Cancer Res 58:4297-4300.
27. Korbelik M. 1996. Induction of tumor immunity by photodynamic therapy. J Clin Laser Med Surg 14:329-334.
28. Korbelik M, Dougherty GJ. 1999. Photodynamic therapy-mediated immune response against subcutaneous mouse tumors. Cancer Res 59:1941-1946.
29. Kroemer G, Zamzami N, Susin SA. 1997. Mitochondrial control of apoptosis. Immuno Today 18:44-51.
30. Lam M, Oleinick NL, Nieminen A-L. 2001. Photodynamic therapy-induced apoptosis in epidermoid carcinoma cells. Reactive oxygen species and mitochondrial inner membrane permeabilization. J Biol Chem 276:47379-47386.
31. Liu X, Zou H, Slaughter C, Wang X. 1997. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89:175-184.
32. Moan J, Berg K. 1991. The photodegradation of porphyrins in cells can be used to estimate the lifetime of singlet oxygen. Photochem Photobiol 53:549-553.
33. Murant RS, Gibson SL, Hilf R. 1987. Photosensitizing effects of Photofrin II on the site-selected mitochondrial enzymes adenylate kinase and monoamine oxidase. Cancer Res 47:4323-4328.
34. Naito M, Nagashima K, Mashima T, Tsuruo T. 1997. Phosphatidylserine externalization is a downstream event of interleukin-1 betaconverting enzyme family protease activation during apoptosis. Blood 89:2060-2066.
35. Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin T-T, Yu VL, Miller DK. 1995. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43.
36. Pagano RE, Martin OC, Kang HC, Haugland RP. 1991. A novel fluorescent ceramide analogue for studying membrane traffic in animal cells: Accumulation at the Golgi apparatus results in altered spectral properties of the sphingolipid precursor. J Cell Biol 113: 1267-1279.
37. Pass HI. 1993. Photodynamic therapy in oncology: Mechanisms and clinical use. J Natl Cancer Inst 85:443-456.
38. Pastorino JG, Simbula G, Yamamoto K, Glascott PA, Jr., Rothman RJ, Farber JL. 1996. The cytotoxicity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J Biol Chem 271:29792-29798.
39. Peng Q, Moan J, Nesland JM. 1996. Correlation of subcellular and intratumoral photosensitizer location with ultrastructural features after photodynamic therapy. Ultrastruct Pathol 20:109-129.
40. Roberts WG, Liaw LH, Berns MW. 1989. In vitro photosensitization II. An electron microscopy study of cellular destruction with mono-L-aspartyl chlorin e6 and photofrin II. Lasers Surg Med 9:102-108.
41. Rousset N, Vonarx R, Eleouet S, Carre J, Bourre L, Lajat Y, Patrice T. 2000. Cellular distribution and phototoxicity of benzoporphyrin derivative and photofrin. Res Exp Med 199:341-357.
42. Salet C. 1986. Hematoporphyrin and hematoporphyrin-derivative photosensitization of mitochondria. Biochimie 68:865-868.
43. Tao JS, Sanghera JS, Pelech SL, Wong G, Levy JG. 1996. Stimulation of stress-activated protein kinase and p38 HOG1 kinase in murine keratinocytes following photodynamic therapy with benzoporphyrin derivative. J Biol Chem 271:27107-27115.
44. Thomas JP, Girotti AW. 1989. Role of lipid peroxidation in hemato-porphyrin derivative-sensitized photokilling of tumor cells: Protective effects of glutathione peroxidase. Cancer Res 49:1682-1686.
45. Vermes I, Haanen C, Reutelingsperger C. 2000. Flow cytometry of apoptotic cell death. J Immunol Methods 243:167-190.
46. Woodburn KW, Fan Q, Miles DR, Kessel D, Luo Y, Young SW. 1997. Localization and efficacy analysis of the phototherapeutic lutetium texaphyrin (PCI-0123) in the murine EMT6 sarcoma model. Photochem Photobiol 65:410-415.
47. Wyld L, Reed MW, Brown NJ. 2001. Differential cell death response to photodynamic therapy is dependent on dose and cell type. Br J Cancer 84:1384-1386.
48. Xue L, He J, Oleinick NL. 1999. Promotion of photodynamic therapy-induced apoptosis by stress kinases. Cell Death Differ 6:855-864.
49. Yu J-S, Chen H-C, Yang S-D. 1997. Reversible tyrosine phosphorylation/dephosphorylation of proline-directed protein kinase FA/GSK-3α in A431 cells. J Cell Physiol 171:95-103.
50. Yu A, Byers DM, Ridgway ND, McMaster CR, Cook HW. 2000. Preferential externalization of newly synthesized phosphatidylserine in apoptotic U937 cells is dependent on caspase-mediated pathways. Biochim Biophys Acta 1487:296-308.
51. Zaidi SI, Oleinick NL, Zaim MT, Mukhtar H. 1993. Apoptosis during photodynamic therapy-induced ablation of RIF-1 tumors in C3H mice: Electron microscopic, histopathologic and biochemical evidence. Photochem Photobiol 58:771-776.
52. Zhu N, Wang Z. 1997. An assay for DNA fragmentation in apoptosis without phenol/chloroform extraction and ethanol precipitation. Anal Biochem 246:155-158.