Reactive oxygen species, antioxidants, and the mammalian thioredoxin system

Free Radical Biology and Medicine

Volumn 31, Issue 11, 2001, Pages 1287-1312

  Nordberg, Jonas ^a   Arnér, Elias S J ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Antioxidant; Dinitrohalobenzene; Free radicals; Inflammation; Oxidative stress; Reactive oxygen species; Redox regulation; Thioredoxin; Thioredoxin reductase

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CATALASE; GLUTATHIONE PEROXIDASE; HYDROGEN PEROXIDE; HYDROXYL RADICAL; ISOPROTEIN; NITRIC OXIDE; OXIDOREDUCTASE; REACTIVE OXYGEN METABOLITE; SELENIUM DERIVATIVE; SUPEROXIDE; SUPEROXIDE DISMUTASE; THIOCTIC ACID; THIOREDOXIN; THIOREDOXIN REDUCTASE; UBIDECARENONE; UBIQUINONE;

ANTIOXIDANT ACTIVITY; CATALYSIS; CELL FUNCTION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; IMMUNITY; IMMUNOSTIMULATION; INFLAMMATION; MAMMAL; MOLECULAR INTERACTION; NONHUMAN; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY MECHANISM; REVIEW; VITILIGO;

ANIMALS; ANTIOXIDANTS; DINITROCHLOROBENZENE; ENZYME INHIBITORS; HUMANS; OXIDANTS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SUBSTRATE SPECIFICITY; THIOREDOXIN; THIOREDOXIN REDUCTASE (NADPH);

MAMMALIA;

EID: 0035584857     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00724-9     Document Type: Review

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271. Induction of thioredoxin and thioredoxin reductase gene expression in lungs of newborn primates by oxygen
272. The core promoter of human thioredoxin reductase 1: Cloning, transcriptional activity and Oct-1, Sp1 and Sp3 binding reveal a housekeeping-type promoter for the ARE-regulated gene
273. The mechanisms and evaluation of chemically induced allergy
274. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules
275. Signals involved in the early TH1/TH2 polarization of an immune response depending on the type of antigen
276. Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen
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279. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection
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282. Possible functional impairment of Langerhans' cells in vitiliginous skin. Reduced ability to elicit dinitrochlorobenzene contact sensitivity reaction and decreased stimulatory effect in the allogeneic mixed skin cell lymphocyte culture reaction
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284. Interaction of alpha-lipoic acid enantiomers and homologues with the enzyme components of the mammalian pyruvate dehydrogenase complex
285. Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms
286. Cytokine production by CD4+ and CD8+ T cells in mice following primary exposure to chemical allergens: Evidence for functional differentiation of T lymphocytes in vivo
287. Classification of chemical allergens according to cytokine secretion profiles of murine lymph node cells
288. CD40 function in nonhematopoietic cells. Nuclear factor kappa B mobilization and induction of IL-6 production
289. Enhanced expression of IL-8 in normal human keratinocytes and human keratinocyte cell line HaCaT in vitro after stimulation with contact sensitizers, tolerogens and irritants
290. Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens
291. Induction of interleukin-12/p40 by superantigens in macrophages is mediated by activation of nuclear factor-kappaB
292. Human keratinocytes constitutively express interleukin-18 and secrete biologically active interleukin-18 after treatment with pro-inflammatory mediators and dinitrochlorobenzene
293. Differential induction of cutaneous TNF-alpha and IL-6 by topically applied chemicals
294. Simple chemicals can induce maturation and apoptosis of dendritic cells
295. Direct observation of a free radical interaction between vitamin E and vitamin C
296. Kinetic study of the reaction of vitamin C with vitamin E radicals (tocopheroxyls) in solution