Novel lipid modifications of secreted protein signals

Annual Review of Biochemistry

Volumn 73, Issue , 2004, Pages 891-923

  Mann, Randall K ^a   Beachy, Philip A ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autoproteolysis; Cholesterol; Hedgehog proteins; Protein acylation; Wnt proteins

Indexed keywords

LIPID; MORPHOGEN; MUTANT PROTEIN; SONIC HEDGEHOG PROTEIN; THIOESTER; WNT PROTEIN;

NEMATODE; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; REVIEW; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; ANIMALS; BODY PATTERNING; CHOLESTEROL; DROSOPHILA PROTEINS; EMBRYONIC INDUCTION; HEDGEHOG PROTEINS; HUMANS; LIPIDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PALMITIC ACIDS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SORTING SIGNALS; PROTO-ONCOGENE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TRANS-ACTIVATORS; WNT PROTEINS;

ERINACEIDAE; HEXAPODA; METAZOA; NEMATODA; VERTEBRATA;

EID: 2942742564     PISSN: 00664154     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.biochem.73.011303.073933     Document Type: Review

References (139)

1. Ingham PW, McMahon AP. 2001. Genes Dev. 15:3059-87
2. Muenke M, Beachy PA. 2001. In The Metabolie and Molecular Bases of Inherited Disease, ed. CR Scriver, AL Beaudet, WS Sly, D Valle, B Childs, et al., pp. 6203-30. New York: McGraw-Hill
3. Wodarz A, Nusse R. 1998. Annu. Rev. Cell Dev. Biol. 14:59-88
4. Miller JR. 2002. Genome Biol. 3:1-15
5. Nusse R. 2003. The Wnt gene homepage. www.stanford.edu/~rnusse/wntwindow. html
6. Batlle E, Henderson JT, Beghtel H, van den Born MM, Sancho E, et al. 2002. Cell 111:251-63
7. van de Wetering M, Sancho E, Verweij C, de Lau W, Oving I, et al. 2002. Cell 111:241-50
8. Machold R, Hayashi S, Rutlin M, Muzumdar MD, Nery S, et al. 2003. Neuron 39:937-50
9. Pinto D, Gregorieff A, Begthel H, Clevers H. 2003. Genes Dev. 17:1709-13
10. Reya T, Duncan AW, Ailles L, Domen J, Scherer DC, et al. 2003. Nature 423:409-14
11. Watkins DN, Berman DM, Burkholder SG, Wang BL, Beachy PA, Baylin SB. 2003. Nature 422:313-17
12. Berman DM, Karhadkar SS, Maitra A, de Oca RM, Gerstenblith MR, et al. 2003. Nature 425:846-51
13. Thayer SP, Di Magliano MP, Heiser PW, Nielsen CM, Roberts DJ, et al. 2003. Nature 425:851-56
14. Taipale J, Beachy PA. 2001. Nature 411:349-54
15. Reya T, Morrison SJ, Clarke MF, Weissman IL. 2001. Nature 414:105-11
16. Giles RH, van Es JH, Clevers H. 2003. Biochim. Biophys. Acta 1653:1-24
17. Ornitz DM, Itoh N. 2001. Genome Biol. 2:REVIEWS3005. pp. 1-12; PMID: 11276432
18. Annes JP, Munger JS, Rifkin DB. 2003. J. Cell Sci. 116:217-24
19. Kawano Y, Kypta R. 2003. J. Cell Sci. 116:2627-34
20. Smith WC. 1999. Trends Genet. 15:3-5
21. Mann RK, Beachy PA. 2000. Biochim. Biophys. Acta 1529:188-202
22. Lee JJ, Ekker SC, von Kessler DP, Porter JA, Sun BI, Beachy PA. 1994. Science 266:1528-37
23. Porter JA, von Kessler DP, Ekker SC, Young KE, Lee JJ, et al. 1995. Nature 374:363-66
24. Porter JA, Young KE, Beachy PA. 1996. Science 274:255-59
25. Ekker SC, Ungar AR, Greenstein P, von Kessler DP, Porter JA, et al. 1995. Curr. Biol. 5:944-55
26. Fan CM, Porter JA, Chiang C, Chang DT, Beachy PA, Tessier-Lavigne M. 1995. Cell 81:457-65
27. Hynes M, Porter JA, Chiang C, Chang DT, Tessier-Lavigne M, et al. 1995. Neuron 1:35-44
28. Lai C-J, Ekker SC, Beachy PA, Moon RT. 1995. Development 121:2349-60
29. López-Martínez A, Chang DT, Chiang C, Porter JA, Ros MA, et al. 1995. Curr. Biol. 5:791-96
30. Marti E, Bumcrot DA, Takada R, McMahon AP. 1995. Nature 375:322-25
31. Roelink H, Porter JA, Chiang C, Tanabe Y, Chang DT, et al. 1995. Cell 81:445-55
32. Porter JA, Ekker SC, Park WJ, von Kessler DP, Young KE, et al. 1996. Cell 86:21-34
33. Dawson PE, Muir TW, Clark-Lewis I, Kent SB. 1994. Science 266:776-79
34. Muir TW. 2003. Annu. Rev. Biochem. 72:249-89
35. Roessler E, Belloni E, Gaudenz K, Jay P, Berta P, et al. 1996. Nat. Genet. 14:357-60
36. Roessler E, Belloni E, Gaudenz K, Vargas F, Scherer SW, et al. 1997. Hum. Mol. Genet. 6:1847-53
37. Cooper MK, Porter JA, Young KE, Beachy PA. 1998. Science 280:1603-7
38. Cenedella RJ. 2001. Ophthalmic Res. 33:210-16
39. Beachy PA, Cooper MK, Young KE, von Kessler DP, Park WJ, et al. 1997. Cold Spring Harbor Symp. Quant. Biol. 62:191-204
40. Perler FB. 1998. Nat. Struct. Biol. 5:249-52
41. Hochstrasser M. 1996. Annu. Rev. Genet. 30:405-39
42. Chu CT, Pizzo SV. 1994. Lab. Investig. 71:792-812
43. van Poelje PD, Snell EE. 1990. Annu. Rev. Biochem. 59:29-59
44. Brannigan JA, Dodson G, Duggleby HJ, Moody PC, Smith JL, et al. 1995. Nature 378:416-19
45. Guan C, Cui T, Rao V, Liao W, Benner J, et al. 1996. J. Biol. Chem. 271:1732-37
46. Perler FB. 2002. Nucleic Acids Res. 30: 383-84
47. Gogarten JP, Senejani AG, Zhaxybayeva O, Olendzenski L, Hilario E. 2002. Annu. Rev. Microbiol. 56:263-87
48. Xu MQ, Perler FB. 1996. EMBO J. 15:5146-53
49. C. elegans Sequencing Consort. 1998. Science 282:2012-18
50. Burglin TR. 1996. Curr. Biol. 6:1047-50
51. Hall TM, Porter JA, Young KE, Koonin EV, Beachy PA, Leahy DJ. 1997. Cell 91:85-97
52. Aspock G, Kagoshima H, Niklaus G, Burglin TR. 1999. Genome Res. 9:909-23
53. Dalgaard JZ, Moser MJ, Hughey R, Mian IS. 1997. J. Comput. Biol. 4:193-214
54. Pietrokovski S, Henikoff S. 1997. Mol. Gen. Genet. 254:689-95
55. Duan XQ, Gimble FS, Quiocho FA. 1997. Cell 89:555-64
56. Bennett MJ, Schlunegger MP, Eisenberg D. 1995. Protein Sci. 4:2455-68
57. Pepinsky RB, Zeng CH, Wen DY, Rayhorn P, Baker DP, et al. 1998. J. Biol. Chem. 273:14037-45
58. Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, et al. 2000. Nature 406:1005-9
59. Taylor FR, Wen DY, Garber EA, Carmillo AN, Baker DP, et al. 2001. Biochemistry 40:4359-71
60. Williams KP, Rayhorn P, Chi-Rosso G, Garber EA, Strauch KL, et al. 1999. J. Cell Sci. 112(Part 23):4405-14
61. Lee JD, Kraus P, Gaiano N, Nery S, Kohtz J, et al. 2001. Dev. Biol. 233:122-36
62. Kohtz JD, Lee HY, Gaiano N, Segal J, Ng E, et al. 2001. Development 128:2351-63
63. Lewis PM, Dunn MP, McMahon JA, Logan M, Martin JF, et al. 2001. Cell 105:599-612
64. Bijlmakers MJ, Marsh M. 2003. Trends Cell Biol. 13:32-42
65. Linder ME, Deschenes RJ. 2003. Biochemistry 42:4311-20
66. Vilas GL, Berthiaume LG. 2004. Biochem. J. 377(Part 1):121-30
67. Corvi MM, Soltys CL, Berthiaume LG. 2001. J. Biol. Chem. 276:45704-12
68. Dunphy JT, Schroeder H, Leventis R, Greentree WK, Knudsen JK, et al. 2000. Biochim. Biophys. Acta 1485:185-98
69. Lobo S, Greentree WK, Linder ME, Deschenes RJ. 2002. J. Biol. Chem. 277:41268-73
70. Roth AF, Feng Y, Chen L, Davis NG. 2002. J. Cell Biol. 159:23-28
71. Lee JD, Treisman JE. 2001. Curr. Biol. 11:1147-52
72. Chamoun Z, Mann RK, Nellen D, von Kessler DP, Bellotto M, et al. 2001. Science 293:2080-84
73. Amanai K, Jiang J. 2001. Development 128:5119-27
74. Micchelli CA, The I, Selva E, Mogila V, Perrimon N. 2002. Development 129:843-51
75. Hofmann K. 2000. Trends Biochem. Sci. 25:111-12
76. Hancock JF, Magee AI, Childs JE, Marshall CJ. 1989. Cell 57:1167-77
77. Resh MD. 1999. Biochim. Biophys. Acta 1451:1-16
78. Berthiaume LG. 2002. Science STKE152:PE41. PMID:12359913
79. Shahinian S, Silvius JR. 1995. Biochemistry 34:3813-22
80. van den Heuvel M, Harryman-Samos C, Klingensmith J, Perrimon N, Nusse R. 1993. EMBO J. 12:5293-302
81. Kadowaki T, Wilder E, Klingensmith J, Zachary K, Perrimon N. 1996. Genes Dev. 10:3116-28
82. Tanaka K, Okabayashi K, Asashima M, Perrimon N, Kadowaki T. 2000. Eur. J. Biochem. 267:4300-11
83. Tanaka K, Kitagawa Y, Kadowaki T. 2002. J. Biol. Chem. 277:12816-23
84. Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, et al. 2003. Nature 423:448-52
85. Aravind L, Koonin EV. 1998. Curr. Biol. 8:R477-78
86. van Tilbeurgh H, Bezzine S, Cambillau C, Verger R, Carriere F. 1999. Biochim. Biophys. Acta 1441:173-84
87. Burke R, Nellen D, Bellotto M, Hafen E, Senti KA, et al. 1999. Cell 99:803-15
88. Johnson RL, Tabin C. 1995. Cell 81:313-16
89. Hammerschmidt M, Brook A, McMahon AP. 1997. Trends Genet. 13:14-21
90. Ingham PW. 1998. EMBO J. 17:3505-11
91. Goetz JA, Suber LM, Zeng X, Robbins DJ. 2002. BioEssays 24:157-65
92. Wang B, Fallon JF, Beachy PA. 2000. Cell 100:423-34
93. Briscoe J, Chen Y, Jessell TM, Struhl G. 2001. Mol. Cell 7:1279-91
94. Gallet A, Rodriguez R, Ruel L, Therond PP. 2003. Dev. Cell 4:191-204
95. Ma Y, Erkner A, Gong R, Yao S, Taipale J, et al. 2002. Cell 111:63-75
96. Caspary T, Garcia-Garcia MJ, Huangfu D, Eggenschwiler JT, Wyler MR, et al. 2002. Curr. Biol. 12:1628-32
97. Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT. 2002. Development 129:5753-65
98. Zeng X, Goetz JA, Suber LM, Scott WJ Jr, Schreiner CM, Robbins DJ. 2001. Nature 411:716-20
99. McKeegan KS, Borges-Walmsley MI, Walmsley AR. 2003. Trends Microbiol. 11:21-29
100. Murakami S, Nakashima R, Yamashita E, Yamaguchi A. 2002. Nature 419:587-93
101. Goldberg M, Pribyl T, Juhnke S, Nies DH. 1999. J. Biol. Chem. 274:26065-70
102. Guan L, Nakae T. 2001. J. Bacteriol. 183:1734-39
103. Murakami S, Yamaguchi A. 2003. Curr. Opin. Struct. Biol. 13:443-52
104. Yakushi T, Masuda K, Narita S, Matsuyama S, Tokuda H. 2000. Nat. Cell Biol. 2:212-18
105. Rietveld A, Neutz S, Simons K, Eaton S. 1999. J. Biol. Chem. 274:12049-54
106. Lum L, Yao S, Mozer B, Rovescalli A, Von Kessler D, Nirenberg M, Beachy PA. 2003. Science 299:2039-45
107. Desbordes SC, Sanson B. 2003. Development 130:6245-55
108. Han C, Belenkaya TY, Wang B, Lin X. 2004. Development 131:601-11
109. Cooper MK, Wassif CA, Krakowiak PA, Taipale J, Gong R, et al. 2003. Nat. Genet. 33:508-13
110. Chen JK, Taipale J, Cooper MK, Beachy PA. 2002. Genes Dev. 16:2743-48
111. van den Heuvel M, Ingham PW. 1996. Nature 382:547-51
112. Chen Y, Struhl G. 1996. Cell 87:553-63
113. Chen Y, Strahl G. 1998. Development 125:4943-48
114. Murone M, Rosenthal A, de Sauvage FJ. 1999. Curr. Biol. 9:76-84
115. Taipale J, Cooper MK, Maiti T, Beachy PA. 2002. Nature 418:892-97
116. Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ. 1996. Nature 384:176-79
117. Stone DM, Hynes M, Armanini M, Swanson TA, Gu QLJR, et al. 1996. Nature 384:129-34
118. Fuse N, Maiti T, Wang B, Porter JA, Hall TM, et al. 1999. Proc. Natl. Acad. Sci. USA 96:10992-99
119. Martin V, Carrillo G, Torroja C, Guerrero I. 2001. Curr. Biol. 11:601-7
120. Strutt H, Thomas C, Nakano Y, Stark D, Neave B, et al. 2001. Curr. Biol. 11:608-13
121. Johnson RL, Zhou L, Bailey EC. 2002. Dev. Biol. 242:224-35
122. Casanova J, Strahl G. 1993. Nature 362:152-55
123. Gil G, Faust JR, Chin DJ, Goldstein JL, Brown MS. 1985. Cell 41:249-58
124. Hua X, Nohturfft A, Goldstein JL, Brown MS. 1996. Cell 87:415-26
125. Nohturfft A, Brown MS, Goldstein JL. 1998. J. Biol. Chem. 273:17243-50
126. Brown MS, Goldstein JL. 1999. Proc. Natl. Acad. Sci. USA 96:11041-48
127. Edwards PA, Tabor D, Kast HR, Venkateswaran A. 2000. Biochim. Biophys. Acta 1529:103-13
128. Kuwabara PE, Labouesse M. 2002. Trends Genet. 18:193-201
129. Perrimon N. 1996. Cell 86:513-16
130. Bellaiche Y, The I, Perrimon N. 1998. Nature 394:85-88
131. Lind T, Tufaro F, McCormick C, Lindahl U, Lidholt K. 1998. J. Biol. Chem. 273:26265-68
132. McCormick C, Leduc Y, Martindale D, Mattison K, Esford LE, et al. 1998. Nat. Genet. 19:158-61
133. McCormick C, Duncan G, Goutsos KT, Tufaro F. 2000. Proc. Natl. Acad. Sci. USA 97:668-73
134. Toyoda H, Kinoshita-Toyoda A, Selleck SB. 2000. J. Biol. Chem. 275:2269-75
135. Toyoda H, Kinoshita-Toyoda A, Fox B, Selleck SB. 2000. J. Biol. Chem. 275:21856-61
136. The I, Bellaiche Y, Perrimon N. 1999. Mol. Cell 4:633-39
137. Thompson JD, Gibson TJ, Plewniak F, Jeanmougin F, Higgins DG. 1997. Nucleic Acids Res. 25:4876-82
138. Hall TM, Porter JA, Beachy PA, Leahy DJ. 1995. Nature 378:212-16
139. Chuang PT, McMahon AP. 1999. Nature 397:617-21