-
1
-
-
0031433171
-
Multiple roles of cholesterol in hedgehog protein biogenesis and signaling
-
Beachy, P.A., Cooper, M.K., Young, K.E., von Kessler, D.P., Park, W.J., Hall, T.M., Leahy, D.J., and Porter, J.A. (1997). Multiple roles of cholesterol in hedgehog protein biogenesis and signaling. Cold Spring Harb. Symp. Quant. Biol. 62, 191-204.
-
(1997)
Cold Spring Harb. Symp. Quant. Biol.
, vol.62
, pp. 191-204
-
-
Beachy, P.A.1
Cooper, M.K.2
Young, K.E.3
von Kessler, D.P.4
Park, W.J.5
Hall, T.M.6
Leahy, D.J.7
Porter, J.A.8
-
2
-
-
0032474837
-
Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
-
Bellaiche, Y., Theé , I., and Perrimon, N. (1998). Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394, 85-88.
-
(1998)
Nature
, vol.394
, pp. 85-88
-
-
Bellaiche, Y.1
Theé, I.2
Perrimon, N.3
-
3
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand, A.H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
4
-
-
0030448030
-
Expression and changing distribution of the human transferrin receptor in developing Drosophila oocytes and embryos
-
Bretscher, M.S. (1996). Expression and changing distribution of the human transferrin receptor in developing Drosophila oocytes and embryos. J. Cell Sci. 109, 3113-3119.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 3113-3119
-
-
Bretscher, M.S.1
-
5
-
-
0033598964
-
Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells
-
Burke, R., Nellen, D., Bellotto, M., Hafen, E., Senti, K.A., Dickson, B.J., and Basler, K. (1999). Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells. Cell 99, 803-815.
-
(1999)
Cell
, vol.99
, pp. 803-815
-
-
Burke, R.1
Nellen, D.2
Bellotto, M.3
Hafen, E.4
Senti, K.A.5
Dickson, B.J.6
Basler, K.7
-
6
-
-
0000077409
-
Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal
-
Chamoun, Z., Mann, R.K., Nellen, D., von Kessler, D.P., Bellotto, M., Beachy, P.A., and Basler, K. (2001). Skinny hedgehog, an acyltransferase required for palmitoylation and activity of the hedgehog signal. Science 2, 2.
-
(2001)
Science
, vol.2
, pp. 2
-
-
Chamoun, Z.1
Mann, R.K.2
Nellen, D.3
von Kessler, D.P.4
Bellotto, M.5
Beachy, P.A.6
Basler, K.7
-
7
-
-
0030300085
-
The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
-
Chou, T.B., and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
-
(1996)
Genetics
, vol.144
, pp. 1673-1679
-
-
Chou, T.B.1
Perrimon, N.2
-
8
-
-
0033639077
-
Gradient formation of the TGF-beta homolog Dpp
-
Entchev, E.V., Schwabedissen, A., and Gonzalez-Gaitan, M. (2000). Gradient formation of the TGF-beta homolog Dpp. Cell 103, 981-991.
-
(2000)
Cell
, vol.103
, pp. 981-991
-
-
Entchev, E.V.1
Schwabedissen, A.2
Gonzalez-Gaitan, M.3
-
9
-
-
0027817446
-
Genetic analysis of hedgehog signalling in the Drosophila embryo
-
Forbes, A.J., Nakano, Y., Taylor, A.M., and Ingham, P.W. (1993). Genetic analysis of hedgehog signalling in the Drosophila embryo. Dev. Suppl., 115-124.
-
(1993)
Dev. Suppl.
, pp. 115-124
-
-
Forbes, A.J.1
Nakano, Y.2
Taylor, A.M.3
Ingham, P.W.4
-
10
-
-
0032515945
-
Identification, sequence and developmental expression of invertebrate flotillins from Drosophila melanogaster
-
Galbiati, F., Volonte, D., Goltz, J.S., Steele, Z., Sen, J., Jurcsak, J., Stein, D., Stevens, L., and Lisanti, M.P. (1998). Identification, sequence and developmental expression of invertebrate flotillins from Drosophila melanogaster. Gene 210, 229-237.
-
(1998)
Gene
, vol.210
, pp. 229-237
-
-
Galbiati, F.1
Volonte, D.2
Goltz, J.S.3
Steele, Z.4
Sen, J.5
Jurcsak, J.6
Stein, D.7
Stevens, L.8
Lisanti, M.P.9
-
11
-
-
0034521484
-
Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila
-
Gallet, A., Angelats, C., Kerridge, S., and Therond, P.P. (2000). Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila. Development 127, 5509-5522.
-
(2000)
Development
, vol.127
, pp. 5509-5522
-
-
Gallet, A.1
Angelats, C.2
Kerridge, S.3
Therond, P.P.4
-
12
-
-
0035823004
-
Argosomes: A potential vehicle for the spread of morphogens through epithelia
-
Greco, V., Hannus, M., and Eaton, S. (2001). Argosomes: a potential vehicle for the spread of morphogens through epithelia. Cell 106, 633-645.
-
(2001)
Cell
, vol.106
, pp. 633-645
-
-
Greco, V.1
Hannus, M.2
Eaton, S.3
-
13
-
-
0035479021
-
Divide and conquer: Pattern formation in Drosophila embryonic epidermis
-
Hatini, V., and DiNardo, S. (2001). Divide and conquer: pattern formation in Drosophila embryonic epidermis. Trends Genet. 17, 574-579.
-
(2001)
Trends Genet.
, vol.17
, pp. 574-579
-
-
Hatini, V.1
DiNardo, S.2
-
14
-
-
0025823967
-
Multiple modes of engrailed regulation in the progression towards cell fate determination
-
Heemskerk, J., DiNardo, S., Kostriken, R., and O'Farrell, P.H. (1991). Multiple modes of engrailed regulation in the progression towards cell fate determination. Nature 352, 404-410.
-
(1991)
Nature
, vol.352
, pp. 404-410
-
-
Heemskerk, J.1
DiNardo, S.2
Kostriken, R.3
O'Farrell, P.H.4
-
15
-
-
12944272018
-
Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1
-
Incardona, J.P., Lee, J.H., Robertson, C.P., Enga, K., Kapur, R.P., and Roelink, H. (2000). Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1. Proc. Natl. Acad. Sci. USA 97, 12044-12049.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12044-12049
-
-
Incardona, J.P.1
Lee, J.H.2
Robertson, C.P.3
Enga, K.4
Kapur, R.P.5
Roelink, H.6
-
16
-
-
0026516635
-
Boundaries and fields in early embryos
-
Ingham, P.W., and Martinez Arias, A. (1992). Boundaries and fields in early embryos. Cell 24, 221-235.
-
(1992)
Cell
, vol.24
, pp. 221-235
-
-
Ingham, P.W.1
Martinez Arias, A.2
-
17
-
-
0029278749
-
Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing
-
Ingham, P.W., and Fietz, M.J. (1995). Quantitative effects of hedgehog and decapentaplegic activity on the patterning of the Drosophila wing. Curr. Biol. 5, 432-440.
-
(1995)
Curr. Biol.
, vol.5
, pp. 432-440
-
-
Ingham, P.W.1
Fietz, M.J.2
-
18
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham, P.W., and McMahon, A.P. (2001). Hedgehog signaling in animal development: paradigms and principles. Genes Dev. 15, 3059-3087.
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
19
-
-
0036733753
-
Cholesterol modification of Hedgehog family proteins
-
Jeong, J., and McMahon, A.P. (2002). Cholesterol modification of Hedgehog family proteins. J. Clin. Invest. 110, 591-596.
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 591-596
-
-
Jeong, J.1
McMahon, A.P.2
-
20
-
-
0034931149
-
N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons
-
Kohtz, J.D., Lee, H.Y., Gaiano, N., Segal, J., Ng, E., Larson, T., Baker, D.P., Garber, E.A., Williams, K.P., and Fishell, G. (2001). N-terminal fatty-acylation of sonic hedgehog enhances the induction of rodent ventral forebrain neurons. Development 128, 2351-2363.
-
(2001)
Development
, vol.128
, pp. 2351-2363
-
-
Kohtz, J.D.1
Lee, H.Y.2
Gaiano, N.3
Segal, J.4
Ng, E.5
Larson, T.6
Baker, D.P.7
Garber, E.A.8
Williams, K.P.9
Fishell, G.10
-
21
-
-
0036534286
-
The sterol-sensing domain: Multiple families, a unique role?
-
Kuwabara, P.E., and Labouesse, M. (2002). The sterol-sensing domain: multiple families, a unique role? Trends Genet. 18, 193-201.
-
(2002)
Trends Genet.
, vol.18
, pp. 193-201
-
-
Kuwabara, P.E.1
Labouesse, M.2
-
22
-
-
0035337027
-
An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development
-
Lee, J.D., Kraus, P., Gaiano, N., Nery, S., Kohtz, J., Fishell, G., Loomis, C.A., and Treisman, J.E. (2001). An acylatable residue of Hedgehog is differentially required in Drosophila and mouse limb development. Dev. Biol. 233, 122-136.
-
(2001)
Dev. Biol.
, vol.233
, pp. 122-136
-
-
Lee, J.D.1
Kraus, P.2
Gaiano, N.3
Nery, S.4
Kohtz, J.5
Fishell, G.6
Loomis, C.A.7
Treisman, J.E.8
-
23
-
-
0026783674
-
Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
-
Lee, J.J., von Kessler, D.P., Parks, S., and Beachy, P.A. (1992). Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50.
-
(1992)
Cell
, vol.71
, pp. 33-50
-
-
Lee, J.J.1
von Kessler, D.P.2
Parks, S.3
Beachy, P.A.4
-
24
-
-
0035368725
-
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1
-
Lewis, P.M., Dunn, M.P., McMahon, J.A., Logan, M., Martin, J.F., St-Jacques, B., and McMahon, A.P. (2001). Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell 105, 599-612.
-
(2001)
Cell
, vol.105
, pp. 599-612
-
-
Lewis, P.M.1
Dunn, M.P.2
McMahon, J.A.3
Logan, M.4
Martin, J.F.5
St-Jacques, B.6
McMahon, A.P.7
-
25
-
-
0032500662
-
The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate
-
Lind, T., Tufaro, F., McCormick, C., Lindahl, U., and Lidholt, K. (1998). The putative tumor suppressors EXT1 and EXT2 are glycosyltransferases required for the biosynthesis of heparan sulfate. J. Biol. Chem. 273, 26265-26268.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26265-26268
-
-
Lind, T.1
Tufaro, F.2
McCormick, C.3
Lindahl, U.4
Lidholt, K.5
-
26
-
-
0037020216
-
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched
-
Ma, Y., Erkner, A., Gong, R., Yao, S., Taipale, J., Basler, K., and Beachy, P.A. (2002). Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell 111, 63-75.
-
(2002)
Cell
, vol.111
, pp. 63-75
-
-
Ma, Y.1
Erkner, A.2
Gong, R.3
Yao, S.4
Taipale, J.5
Basler, K.6
Beachy, P.A.7
-
27
-
-
0031837107
-
The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate
-
McCormick, C., Leduc, Y., Martindale, D., Mattison, K., Esford, L.E., Dyer, A.P., and Tufaro, F. (1998). The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate. Nat. Genet. 19, 158-161.
-
(1998)
Nat. Genet.
, vol.19
, pp. 158-161
-
-
McCormick, C.1
Leduc, Y.2
Martindale, D.3
Mattison, K.4
Esford, L.E.5
Dyer, A.P.6
Tufaro, F.7
-
28
-
-
0034699331
-
CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells
-
Michaux, G., Gansmuller, A., Hindelang, C., and Labouesse, M. (2000). CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells. Curr. Biol. 10, 1098-1107.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1098-1107
-
-
Michaux, G.1
Gansmuller, A.2
Hindelang, C.3
Labouesse, M.4
-
29
-
-
0024254534
-
Requirements for hedgehog a segmental polarity gene in patterning larval and adult cuticle of Drosophila
-
Mohler, J. (1988). Requirements for hedgehog a segmental polarity gene in patterning larval and adult cuticle of Drosophila. Genetics 120, 1061-1072.
-
(1988)
Genetics
, vol.120
, pp. 1061-1072
-
-
Mohler, J.1
-
30
-
-
0029903396
-
Armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila
-
Müller, H.A., and Wieschaus, E. (1996). armadillo, bazooka, and stardust are critical for early stages in formation of the zonula adherens and maintenance of the polarized blastoderm epithelium in Drosophila. J. Cell Biol. 134, 149-163.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 149-163
-
-
Müller, H.A.1
Wieschaus, E.2
-
31
-
-
15444359695
-
Identification of a palmitic acid-modified form of human Sonic hedgehog
-
Pepinsky, R.B., Zeng, C., Wen, D., Rayhorn, P., Baker, D.P., Williams, K.P., Bixler, S.A., Ambrose, C.M., Garber, E.A., Miatkowski, K., et al. (1998). Identification of a palmitic acid-modified form of human Sonic hedgehog. J. Biol. Chem. 273, 14037-14045.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14037-14045
-
-
Pepinsky, R.B.1
Zeng, C.2
Wen, D.3
Rayhorn, P.4
Baker, D.P.5
Williams, K.P.6
Bixler, S.A.7
Ambrose, C.M.8
Garber, E.A.9
Miatkowski, K.10
-
32
-
-
15844386540
-
Hedgehog patterning activity: Role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain
-
Porter, J.A., Ekker, S.C., Park, W.J., von Kessler, D.P., Young, K.E., Chen, C.H., Ma, Y., Woods, A.S., Cotter, R.J., Koonin, E.V., and Beachy, P.A. (1996). Hedgehog patterning activity: role of a lipophilic modification mediated by the carboxy-terminal autoprocessing domain. Cell 86, 21-34.
-
(1996)
Cell
, vol.86
, pp. 21-34
-
-
Porter, J.A.1
Ekker, S.C.2
Park, W.J.3
von Kessler, D.P.4
Young, K.E.5
Chen, C.H.6
Ma, Y.7
Woods, A.S.8
Cotter, R.J.9
Koonin, E.V.10
Beachy, P.A.11
-
33
-
-
0033597141
-
Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains
-
Rietveld, A., Neutz, S., Simons, K., and Eaton, S. (1999). Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains. J. Biol. Chem. 274, 12049-12054.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 12049-12054
-
-
Rietveld, A.1
Neutz, S.2
Simons, K.3
Eaton, S.4
-
34
-
-
0030663064
-
A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing
-
Strigini, M., and Cohen, S.M. (1997). A Hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing. Development 124, 4697-4705.
-
(1997)
Development
, vol.124
, pp. 4697-4705
-
-
Strigini, M.1
Cohen, S.M.2
-
35
-
-
0028178786
-
Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
-
Tabata, T., and Kornberg, T.B. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.
-
(1994)
Cell
, vol.76
, pp. 89-102
-
-
Tabata, T.1
Kornberg, T.B.2
-
36
-
-
0027200833
-
Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo
-
Taylor, A.M., Nakano, Y., Mohler, J., and Ingham, P.W. (1993). Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mech. Dev. 42, 89-96.
-
(1993)
Mech. Dev.
, vol.42
, pp. 89-96
-
-
Taylor, A.M.1
Nakano, Y.2
Mohler, J.3
Ingham, P.W.4
-
37
-
-
0035836505
-
Enhanced potency of human Sonic hedgehog by hydrophobic modification
-
Taylor, F.R., Wen, D., Garber, E.A., Carmillo, A.N., Baker, D.P., Arduini, R.M., Williams, K.P., Weinreb, P.H., Rayhorn, P., Hronowski, X., et al. (2001). Enhanced potency of human Sonic hedgehog by hydrophobic modification. Biochemistry 40, 4359-4371.
-
(2001)
Biochemistry
, vol.40
, pp. 4359-4371
-
-
Taylor, F.R.1
Wen, D.2
Garber, E.A.3
Carmillo, A.N.4
Baker, D.P.5
Arduini, R.M.6
Williams, K.P.7
Weinreb, P.H.8
Rayhorn, P.9
Hronowski, X.10
-
38
-
-
0033636094
-
Dpp gradient formation in the Drosophila wing imaginal disc
-
Teleman, A.A., and Cohen, S.M. (2000). Dpp gradient formation in the Drosophila wing imaginal disc. Cell 103, 971-980.
-
(2000)
Cell
, vol.103
, pp. 971-980
-
-
Teleman, A.A.1
Cohen, S.M.2
-
39
-
-
0033212987
-
Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan
-
Thé , I., Bellaiche, Y., and Perrimon, N. (1999). Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan. Mol. Cell 4, 633-639.
-
(1999)
Mol. Cell
, vol.4
, pp. 633-639
-
-
Thé, I.1
Bellaiche, Y.2
Perrimon, N.3
-
40
-
-
9844220298
-
Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb
-
Yang, Y., Drossopoulou, G., Chuang, P.T., Duprez, D., Marti, E., Bumcrot, D., Vargesson, N., Clarke, J., Niswander, L., McMahon, A., and Tickle, C. (1997). Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation of anteroposterior polarity in the chick limb. Development 124, 4393-4404.
-
(1997)
Development
, vol.124
, pp. 4393-4404
-
-
Yang, Y.1
Drossopoulou, G.2
Chuang, P.T.3
Duprez, D.4
Marti, E.5
Bumcrot, D.6
Vargesson, N.7
Clarke, J.8
Niswander, L.9
McMahon, A.10
Tickle, C.11
-
41
-
-
0035822098
-
A freely diffusible form of Sonic hedgehog mediates long-range signalling
-
Zeng, X., Goetz, J.A., Suber, L.M., Scott, W.J., Jr., Schreiner, C.M., and Robbins, D.J. (2001). A freely diffusible form of Sonic hedgehog mediates long-range signalling. Nature 411, 716-720.
-
(2001)
Nature
, vol.411
, pp. 716-720
-
-
Zeng, X.1
Goetz, J.A.2
Suber, L.M.3
Scott W.J., Jr.4
Schreiner, C.M.5
Robbins, D.J.6
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