β-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/EphrinB

Cell

Volumn 111, Issue 2, 2002, Pages 251-263

  Batlle, Eduard ^a   Henderson, Jeffrey T ^b   Beghtel, Harry ^a   Van den Born, Maaike M W ^a   Sancho, Elena ^a   Huls, Gerwin ^a   Meeldijk, Jan ^a   Robertson, Jennifer ^c   Van de Wetering, Marc ^a   Pawson, Tony ^c,d   Clevers, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY OF TORONTO   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; EPHRIN RECEPTOR; GENE PRODUCT; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL POPULATION; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; GENE DISRUPTION; GENE EXPRESSION REGULATION; GOBLET CELL; INTESTINE ABSORPTION; INTESTINE CRYPT; INTESTINE EPITHELIUM; INTESTINE VILLUS; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROGENY; PROTEIN FUNCTION;

ANIMALIA;

EID: 18644376279     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(02)01015-2     Document Type: Article

References (38)

1. Bienz M., Clevers H. Linking colorectal cancer to Wnt signaling. Cell. 103:2000;311-320.
2. Brambilla R., Schnapp A., Casagranda F., Labrador J.P., Bergemann A.D., Flanagan J.G., Pasquale E.B., Klein R. Membrane-bound LERK2 ligand can signal through three different Eph-related receptor tyrosine kinases 12. EMBO J. 14:1995;3116-3126.
3. Brambilla R., Bruckner K., Orioli D., Bergemann A.D., Flanagan J.G., Klein R. Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol. Cell. Neurosci. 8:1996;199-209.
4. Durbin L., Brennan C., Shiomi K., Cooke J., Barrios A., Shanmugalingam S., Guthrie B., Lindberg R., Holder N. Eph signaling is required for segmentation and differentiation of the somites. Genes Dev. 12:1998;3096-3109.
5. Elowe S., Holland S.J., Kulkarni S., Pawson T. Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction. Mol. Cell. Biol. 21:2001;7429-7441.
6. Flanagan J.G., Vanderhaeghen P. The ephrins and Eph receptors in neural development. Annu. Rev. Neurosci. 21:1998;309-345.
7. Fodde R., Smits R., Clevers H. APC, signal transduction and genetic instability in colorectal cancer. Nat. Rev. Cancer. 1:2001;55-67.
8. Frisen J., Holmberg J., Barbacid M. ephrins and their Eph receptors. multitalented directors of embryonic development EMBO J. 18:1999;5159-5165.
9. Gale N.W., Holland S.J., Valenzuela D.M., Flenniken A., Pan L., Ryan T.E., Henkemeyer M., Strebhardt K., Hirai H., Wilkinson D.G.et al. Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis. Neuron. 17:1996;9-19.
10. Garabedian E.M., Roberts L.J., McNevin M.S., Gordon J.I. Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice. J. Biol. Chem. 272:1997;23729-23740.
11. Heath J.P. Epithelial cell migration in the intestine. Cell Biol. Int. 20:1996;139-146.
12. Henkemeyer M., Orioli D., Henderson J.T., Saxton T.M., Roder J., Pawson T., Klein R. Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell. 86:1996;35-46.
13. Holder N., Klein R. Eph receptors and ephrins. effectors of morphogenesis Development. 126:1999;2033-2044.
14. Horwitz A.R., Parsons J.T. Cell migration - movin' on. Science. 286:1999;1102-1103.
15. Kinzler K.W., Vogelstein B. Lessons from hereditary colorectal cancer. Cell. 87:1996;159-170.
16. Korinek V., Barker N., Moerer P., van Donselaar E., Huls G., Peters P.J., Clevers H. Depletion of epithelial stem-cell compartments in the small intestine of mice lacking TCF-4. Nat. Genet. 19:1998;379-383.
17. Kullander K., Klein R. Mechanisms and functions of eph and ephrin signalling. Nat. Rev. Mol. Cell Biol. 3:2002;475-486.
18. Lickert H., Kispert A., Kutsch S., Kemler R. Expression patterns of Wnt genes in mouse gut development. Mech. Dev. 105:2001;181-184.
19. Meima L., Kljavin I.J., Moran P., Shih A., Winslow J.W., Caras I.W. AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton. Eur. J. Neurosci. 9:1997;177-188. a.
20. Meima L., Moran P., Matthews W., Caras I.W. Lerk2 (ephrin-B1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-A5). Mol. Cell. Neurosci. 9:1997;314-328. b.
21. Mellitzer G., Xu Q., Wilkinson D.G. Eph receptors and ephrins restrict cell intermingling and communication. Nature. 400:1999;77-81.
22. Miao H., Burnett E., Kinch M., Simon E., Wang B. Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nat. Cell Biol. 2:2000;62-69.
23. Orioli D., Henkemeyer M., Lemke G., Klein R., Pawson T. Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 15:1996;6035-6049.
24. Oshima H., Oshima M., Kobayashi M., Tsutsumi M., Taketo M.M. Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice. Cancer Res. 57:1997;1644-1649.
25. Parsons J.T., Martin K.H., Slack J.K., Taylor J.M., Weed S.A. Focal adhesion kinase. a regulator of focal adhesion dynamics and cell movement Oncogene. 19:2000;5606-5613.
26. Pinto D., Robine S., Jaisser F., El Marjou F.E., Louvard D. Regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of small and large intestines. J. Biol. Chem. 274:1999;6476-6482.
27. Polakis P. Wnt siganlling and cancer. Genes Dev. 14:2000;1837-1851.
28. Potten C.S., Loeffler M. Stem cells. attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt Development. 110:1990;1001-1020.
29. Robinson V., Smith A., Flenniken A.M., Wilkinson D.G. Roles of Eph receptors and ephrins in neural crest pathfinding. Cell Tissue Res. 290:1997;265-274.
30. Schaller M.D., Parsons J.T. pp125FAK-dependent tyrosine phosphorylation of paxillin creates a high-affinity binding site for Crk. Mol. Cell. Biol. 15:1995;2635-2645.
31. Schmucker D., Zipursky S.L. Signaling downstream of Eph receptors and ephrin ligands. Cell. 105:2001;701-704.
32. Shamah S.M., Lin M.Z., Goldberg J.L., Estrach S., Sahin M., Hu L., Bazalakova M., Neve R.L., Corfas G., Debant A., Greenberg M.E. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor Ephexin. Cell. 105:2001;233-244.
33. Stappenbeck T.S., Wong M.H., Saam J.R., Mysorekar I.U., Gordon J.I. Notes from some crypt watchers. regulation of renewal in the mouse intestinal epithelium Curr. Opin. Cell Biol. 10:1998;702-709.
34. van de Wetering M., Sancho E., Verweij C., de Lau W., Oving I., Hurlstone A., van der Horn K., Batlle E., Coudreuse D., Haramis A.-P.et al. The β-catenin/TCF4 complex imposes a crypt progenitor phenotype on colorectal cancer cells. Cell. 111:2002;241-250. this issue,
35. Wilkinson D.G. Multiple roles of Eph receptors and ephrins in neural development. Nat. Rev. Neurosci. 2:2001;155-164.
36. Wilkinson D.G. Topographic mapping. organising by repulsion and competition? Curr. Biol. 10:2000;R447-R451.
37. Xu Q., Alldus G., Holder N., Wilkinson D.G. Expression of truncated Sek-1 receptor tyrosine kinase disrupts the segmental restriction of gene expression in the Xenopus and zebrafish hindbrain. Development. 121:1995;4005-4016.
38. Xu Q., Mellitzer G., Robinson V., Wilkinson D.G. In vivo cell sorting in complementary segmental domains mediated by Eph receptors and ephrins. Nature. 399:1999;267-271.