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Volumn 99, Issue 7, 1999, Pages 803-815

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified Hedgehog from signaling cells

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; STEROL;

EID: 0033598964     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)81677-3     Document Type: Article
Times cited : (456)

References (54)
  • 1
    • 0028329349 scopus 로고
    • Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein
    • Basler, K., and Struhl, G. (1994). Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 368, 208-214.
    • (1994) Nature , vol.368 , pp. 208-214
    • Basler, K.1    Struhl, G.2
  • 3
    • 0032474837 scopus 로고    scopus 로고
    • Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion
    • Bellaiche, Y., The, I., and Perrimon, N. (1998). Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion. Nature 394, 85-88.
    • (1998) Nature , vol.394 , pp. 85-88
    • Bellaiche, Y.1    The, I.2    Perrimon, N.3
  • 4
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A.H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 5
    • 0027983638 scopus 로고
    • Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings
    • Capdevila, J., and Guerrero, I. (1994). Targeted expression of the signaling molecule decapentaplegic induces pattern duplications and growth alterations in Drosophila wings. EMBO J. 13, 4459-4468.
    • (1994) EMBO J. , vol.13 , pp. 4459-4468
    • Capdevila, J.1    Guerrero, I.2
  • 6
    • 0030863352 scopus 로고    scopus 로고
    • Niemann-Pick C1 disease gene: Homology to mediators of cholesterol homeostasis
    • Carstea, E.D., et al. (1997). Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis. Science 277, 228-231.
    • (1997) Science , vol.277 , pp. 228-231
    • Carstea, E.D.1
  • 7
    • 0030297553 scopus 로고    scopus 로고
    • Dual roles for patched in sequestering and transducing hedgehog
    • Chen, Y., and Struhl, G. (1996). Dual roles for patched in sequestering and transducing hedgehog. Cell 87, 553-563.
    • (1996) Cell , vol.87 , pp. 553-563
    • Chen, Y.1    Struhl, G.2
  • 8
    • 0032413830 scopus 로고    scopus 로고
    • In vivo evidence that patched and smoothened constitute distinct binding and transducing components of a hedgehog receptor complex
    • Chen, Y., and Struhl, G. (1998). In vivo evidence that patched and smoothened constitute distinct binding and transducing components of a hedgehog receptor complex. Development 125, 4943-4948.
    • (1998) Development , vol.125 , pp. 4943-4948
    • Chen, Y.1    Struhl, G.2
  • 9
    • 0030300085 scopus 로고    scopus 로고
    • The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster
    • Chou, T.B., and Perrimon, N. (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.
    • (1996) Genetics , vol.144 , pp. 1673-1679
    • Chou, T.B.1    Perrimon, N.2
  • 10
    • 0028345607 scopus 로고
    • The wingless signaling pathway and the patterning of the wing margin in Drosophila
    • Couso, J.P., Bishop, S.A., and Martinez Arias, A. (1994). The wingless signaling pathway and the patterning of the wing margin in Drosophila. Development 120, 621-636.
    • (1994) Development , vol.120 , pp. 621-636
    • Couso, J.P.1    Bishop, S.A.2    Martinez Arias, A.3
  • 11
    • 0344244746 scopus 로고    scopus 로고
    • P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: Correlation of physical and cytogenetic maps in chromosomal region 86E-87F
    • Deák, P., et al. (1997). P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: correlation of physical and cytogenetic maps in chromosomal region 86E-87F. Genetics 147, 1697-1722.
    • (1997) Genetics , vol.147 , pp. 1697-1722
    • Deák, P.1
  • 12
    • 0027817446 scopus 로고
    • Genetic analysis of hedgehog signaling in the Drosophila embryo
    • Forbes, A.J., Nakano, Y., Taylor, A.M., and Ingham, P.W. (1993). Genetic analysis of hedgehog signaling in the Drosophila embryo. Development (Suppl.), 115-124.
    • (1993) Development , Issue.SUPPL. , pp. 115-124
    • Forbes, A.J.1    Nakano, Y.2    Taylor, A.M.3    Ingham, P.W.4
  • 13
    • 0021856440 scopus 로고
    • Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme
    • Gil, G., Faust, J.R., Chin, D.J., Goldstein, J.L., and Brown, M.S. (1985). Membrane-bound domain of HMG CoA reductase is required for sterol-enhanced degradation of the enzyme. Cell 41, 249-258.
    • (1985) Cell , vol.41 , pp. 249-258
    • Gil, G.1    Faust, J.R.2    Chin, D.J.3    Goldstein, J.L.4    Brown, M.S.5
  • 14
    • 0029855245 scopus 로고    scopus 로고
    • The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm
    • Golembo, M., Raz, E., and Shilo, B.-Z. (1996). The Drosophila embryonic midline is the site of Spitz processing, and induces activation of the EGF receptor in the ventral ectoderm. Development 122, 3363-3370.
    • (1996) Development , vol.122 , pp. 3363-3370
    • Golembo, M.1    Raz, E.2    Shilo, B.-Z.3
  • 15
    • 0030027059 scopus 로고    scopus 로고
    • Conservation of the hedgehog/patched signaling pathway from flies to mice: Induction of a mouse patched gene by hedgehog
    • Goodrich, L.V., Johnson, R.L., Milenkovic, L., McMahon, J.A., and Scott, M.P. (1996). Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by hedgehog. Genes Dev. 10, 301-312.
    • (1996) Genes Dev. , vol.10 , pp. 301-312
    • Goodrich, L.V.1    Johnson, R.L.2    Milenkovic, L.3    McMahon, J.A.4    Scott, M.P.5
  • 18
    • 0024468746 scopus 로고
    • The Drosophila patched gene encodes a putative membrane protein required for segmental patterning
    • Hooper, J.E., and Scott, M.P. (1989). The Drosophila patched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.
    • (1989) Cell , vol.59 , pp. 751-765
    • Hooper, J.E.1    Scott, M.P.2
  • 19
    • 0030298339 scopus 로고    scopus 로고
    • Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein
    • Hua, X., Nohturfft, A., Goldstein, J.L., and Brown, M.S. (1996). Sterol resistance in CHO cells traced to point mutation in SREBP cleavage-activating protein. Cell 87, 415-426.
    • (1996) Cell , vol.87 , pp. 415-426
    • Hua, X.1    Nohturfft, A.2    Goldstein, J.L.3    Brown, M.S.4
  • 20
    • 0032126734 scopus 로고    scopus 로고
    • Transducing Hedgehog: The story so far
    • Ingham, P.W. (1998). Transducing Hedgehog: the story so far. EMBO J. 17, 3505-3511.
    • (1998) EMBO J. , vol.17 , pp. 3505-3511
    • Ingham, P.W.1
  • 21
    • 0030450052 scopus 로고    scopus 로고
    • The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in wingless processing
    • Kadowaki, T., Wilder, E., Klingensmith, J., Zachary, K., and Perrimon, N. (1996). The segment polarity gene porcupine encodes a putative multitransmembrane protein involved in wingless processing. Genes Dev. 10, 3116-3128.
    • (1996) Genes Dev. , vol.10 , pp. 3116-3128
    • Kadowaki, T.1    Wilder, E.2    Klingensmith, J.3    Zachary, K.4    Perrimon, N.5
  • 22
    • 0030604688 scopus 로고    scopus 로고
    • Morphogens, compartments, and pattern: Lessons from drosophila?
    • Lawrence, P.A., and Struhl, G. (1996). Morphogens, compartments, and pattern: lessons from drosophila? Cell 85, 951-961.
    • (1996) Cell , vol.85 , pp. 951-961
    • Lawrence, P.A.1    Struhl, G.2
  • 23
    • 0029967209 scopus 로고    scopus 로고
    • Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing
    • Lecuit, T., Brook, W.J., Ng, M., Calleja, M., Sun, H., and Cohen, S.M. (1996). Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393.
    • (1996) Nature , vol.381 , pp. 387-393
    • Lecuit, T.1    Brook, W.J.2    Ng, M.3    Calleja, M.4    Sun, H.5    Cohen, S.M.6
  • 24
    • 0026783674 scopus 로고
    • Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog
    • Lee, J.J., von Kessler, D.P., Parks, S., and Beachy, P.A. (1992). Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog. Cell 71, 33-50.
    • (1992) Cell , vol.71 , pp. 33-50
    • Lee, J.J.1    Von Kessler, D.P.2    Parks, S.3    Beachy, P.A.4
  • 28
    • 0027741258 scopus 로고
    • The segment polarity gene hedgehyg is required for progression of the morphogenetic furrow in the developing Drosophila eye
    • Ma, C., Zhou, Y., Beachy, P.A., and Moses, K. (1993). The segment polarity gene hedgehyg is required for progression of the morphogenetic furrow in the developing Drosophila eye. Cell 75, 927-938.
    • (1993) Cell , vol.75 , pp. 927-938
    • Ma, C.1    Zhou, Y.2    Beachy, P.A.3    Moses, K.4
  • 29
    • 0029975823 scopus 로고    scopus 로고
    • Conservation in hedgehog signaling: Induction of a chicken patched homolog by Sonic hedgehog in the developing limb
    • Marigo, V., Scott, M.P., Johnson, R.L., Goodrich, L.V., and Tabin, C.J. (1996). Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233.
    • (1996) Development , vol.122 , pp. 1225-1233
    • Marigo, V.1    Scott, M.P.2    Johnson, R.L.3    Goodrich, L.V.4    Tabin, C.J.5
  • 30
    • 0033582908 scopus 로고    scopus 로고
    • Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus
    • Méthot, N., and Basler, K. (1999). Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus. Cell 96, 819-831.
    • (1999) Cell , vol.96 , pp. 819-831
    • Méthot, N.1    Basler, K.2
  • 31
    • 0030970025 scopus 로고    scopus 로고
    • Hedgehog activity, independent of decapentaplegic, participates in wing disc patterning
    • Mullor, J.L., Calleja, M., Capdevila, J., and Guerrero, I. (1997). Hedgehog activity, independent of decapentaplegic, participates in wing disc patterning. Development 124, 1227-1237.
    • (1997) Development , vol.124 , pp. 1227-1237
    • Mullor, J.L.1    Calleja, M.2    Capdevila, J.3    Guerrero, I.4
  • 32
    • 0009603803 scopus 로고    scopus 로고
    • Sonic hedgehog signaling by the patched-smoothened receptor complex
    • Murone, M., Rosenthal, A., and de Sauvage, F.J. (1999). Sonic hedgehog signaling by the patched-smoothened receptor complex. Curr. Biol. 9, 76-84.
    • (1999) Curr. Biol. , vol.9 , pp. 76-84
    • Murone, M.1    Rosenthal, A.2    De Sauvage, F.J.3
  • 33
    • 0024440611 scopus 로고
    • A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched
    • Nakano, Y., Guerrero, I., Hidalgo, A., Taylor, A., Whittle, J.R., and Ingham, P.W. (1989). A protein with several possible membrane-spanning domains encoded by the Drosophila segment polarity gene patched. Nature 341, 508-513.
    • (1989) Nature , vol.341 , pp. 508-513
    • Nakano, Y.1    Guerrero, I.2    Hidalgo, A.3    Taylor, A.4    Whittle, J.R.5    Ingham, P.W.6
  • 34
    • 0029894568 scopus 로고    scopus 로고
    • Direct and long-range action of a DPP morphogen gradient
    • Nellen, D., Burke, R., Struhl, G., and Basler, K. (1996). Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368.
    • (1996) Cell , vol.85 , pp. 357-368
    • Nellen, D.1    Burke, R.2    Struhl, G.3    Basler, K.4
  • 35
    • 0031213842 scopus 로고    scopus 로고
    • Morphogens and pattern formation
    • Neumann, C., and Cohen, S. (1997). Morphogens and pattern formation. Bioessays 19, 721-729.
    • (1997) Bioessays , vol.19 , pp. 721-729
    • Neumann, C.1    Cohen, S.2
  • 36
    • 0034053414 scopus 로고    scopus 로고
    • Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics
    • in press
    • Newsome, T.P., Åsling, B., and Dickson, B.J. (2000). Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics. Development, in press.
    • (2000) Development
    • Newsome, T.P.1    Åsling, B.2    Dickson, B.J.3
  • 37
    • 0019133661 scopus 로고
    • Mutations affecting segment number and polarity in Drosophila
    • Nüsslein-Volhard, C., and Wieschaus, E. (1980). Mutations affecting segment number and polarity in Drosophila. Nature 287, 795-801.
    • (1980) Nature , vol.287 , pp. 795-801
    • Nüsslein-Volhard, C.1    Wieschaus, E.2
  • 38
    • 0031899024 scopus 로고    scopus 로고
    • Related membrane domains in proteins of sterol sensing and cell signaling provide a glimpse of treasures still buried within the dynamic realm of intracellular metabolic regulation
    • Osborne, T.F., and Rosenfeld, J.M. (1998). Related membrane domains in proteins of sterol sensing and cell signaling provide a glimpse of treasures still buried within the dynamic realm of intracellular metabolic regulation. Curr. Opin. Lipidol. 9, 137-140.
    • (1998) Curr. Opin. Lipidol. , vol.9 , pp. 137-140
    • Osborne, T.F.1    Rosenfeld, J.M.2
  • 40
    • 0031040449 scopus 로고    scopus 로고
    • Induction of Drosophila eye development by decapentaplegic
    • Pignoni, F., and Zipursky, S.L. (1997). Induction of Drosophila eye development by decapentaplegic. Development 124, 271-278.
    • (1997) Development , vol.124 , pp. 271-278
    • Pignoni, F.1    Zipursky, S.L.2
  • 41
    • 0028948811 scopus 로고
    • The product of hedgehog auto-proteolytic cleavage active in local and long-range signaling
    • Porter, J.A., von Kessler, D.P., Ekker, S.C., Young, K.E., Lee, J.J., Moses, K., and Beachy, P.A. (1995). The product of hedgehog auto-proteolytic cleavage active in local and long-range signaling. Nature 374, 363-366.
    • (1995) Nature , vol.374 , pp. 363-366
    • Porter, J.A.1    Von Kessler, D.P.2    Ekker, S.C.3    Young, K.E.4    Lee, J.J.5    Moses, K.6    Beachy, P.A.7
  • 43
    • 0029844192 scopus 로고    scopus 로고
    • Cholesterol modification of hedgehog signaling proteins in animal development
    • Porter, J.A., Young, K.E., and Beachy, P.A. (1996b). Cholesterol modification of hedgehog signaling proteins in animal development. Science 274, 255-259.
    • (1996) Science , vol.274 , pp. 255-259
    • Porter, J.A.1    Young, K.E.2    Beachy, P.A.3
  • 44
    • 0030005248 scopus 로고    scopus 로고
    • The fu gene discriminates between pathways to control dpp expression in Drosophila imaginal discs
    • Sanchez-Herrero, E., Couso, J.P., Capdevila, J., and Guerrero, I. (1996). The fu gene discriminates between pathways to control dpp expression in Drosophila imaginal discs. Mech. Dev. 55, 159-170.
    • (1996) Mech. Dev. , vol.55 , pp. 159-170
    • Sanchez-Herrero, E.1    Couso, J.P.2    Capdevila, J.3    Guerrero, I.4
  • 45
    • 0028809104 scopus 로고
    • Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster
    • Slusarski, D.C., Motzny, C.K., and Holmgren, R. (1995). Mutations that alter the timing and pattern of cubitus interruptus gene expression in Drosophila melanogaster. Genetics 139, 229-240.
    • (1995) Genetics , vol.139 , pp. 229-240
    • Slusarski, D.C.1    Motzny, C.K.2    Holmgren, R.3
  • 46
    • 0030663064 scopus 로고    scopus 로고
    • A hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing
    • Strigini, M., and Cohen, S.M. (1997). A hedgehog activity gradient contributes to AP axial patterning of the Drosophila wing. Development 124, 4697-4705.
    • (1997) Development , vol.124 , pp. 4697-4705
    • Strigini, M.1    Cohen, S.M.2
  • 47
    • 0028178786 scopus 로고
    • Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs
    • Tabata, T., and Kornberg, T.B. (1994). Hedgehog is a signaling protein with a key role in patterning Drosophila imaginal discs. Cell 76, 89-102.
    • (1994) Cell , vol.76 , pp. 89-102
    • Tabata, T.1    Kornberg, T.B.2
  • 48
    • 0027200833 scopus 로고
    • Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo
    • Taylor, A.M., Nakano, Y., Mohler, J., and Ingham, P.W. (1993). Contrasting distributions of patched and hedgehog proteins in the Drosophila embryo. Mech. Dev. 42, 89-96.
    • (1993) Mech. Dev. , vol.42 , pp. 89-96
    • Taylor, A.M.1    Nakano, Y.2    Mohler, J.3    Ingham, P.W.4
  • 49
    • 0027368963 scopus 로고
    • Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein
    • van den Heuvel, M., Harryman-Samos, C., Klingensmith, J., Perrimon, N., and Nusse, R. (1993). Mutations in the segment polarity genes wingless and porcupine impair secretion of the wingless protein. EMBO J. 12, 5293-5302.
    • (1993) EMBO J. , vol.12 , pp. 5293-5302
    • Van Den Heuvel, M.1    Harryman-Samos, C.2    Klingensmith, J.3    Perrimon, N.4    Nusse, R.5
  • 50
    • 0026716643 scopus 로고
    • Membrane protein structure prediction, hydrophobicity analysis and the positive-inside rule
    • von Heijne, G.(1992). Membrane protein structure prediction, hydrophobicity analysis and the positive-inside rule. J. Mol. Biol. 225, 487-494.
    • (1992) J. Mol. Biol. , vol.225 , pp. 487-494
    • Von Heijne, G.1
  • 51
    • 0032582797 scopus 로고    scopus 로고
    • An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg
    • Wasserman, J.D., and Freeman, M. (1998). An autoregulatory cascade of EGF receptor signaling patterns the Drosophila egg. Cell 95, 355-364.
    • (1998) Cell , vol.95 , pp. 355-364
    • Wasserman, J.D.1    Freeman, M.2
  • 52
    • 0027267041 scopus 로고
    • Analysis of genetic mosaics in developing and adult Drosophila tissues
    • Xu, T., and Rubin, G.M. (1993). Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 117, 1223-1237.
    • (1993) Development , vol.117 , pp. 1223-1237
    • Xu, T.1    Rubin, G.M.2
  • 53
    • 0029079881 scopus 로고
    • Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing
    • Zecca, M., Basler, K., and Struhl, G. (1995). Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278.
    • (1995) Development , vol.121 , pp. 2265-2278
    • Zecca, M.1    Basler, K.2    Struhl, G.3
  • 54
    • 0024292597 scopus 로고
    • Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila
    • Zinn, K., McAllister, L., and Goodman, C.S. (1988). Sequence analysis and neuronal expression of fasciclin I in grasshopper and Drosophila. Cell 53, 577-587.
    • (1988) Cell , vol.53 , pp. 577-587
    • Zinn, K.1    McAllister, L.2    Goodman, C.S.3


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