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Volumn 112, Issue 3, 2003, Pages 480-487

Regulatory T cells control the development of allergic disease and asthma

Author keywords

Allergy; Asthma; T regulatory cells; TH2

Indexed keywords

ADENOVIRUS VECTOR; ALLERGEN; CD4 ANTIGEN; COMPLEMENTARY DNA; INTERLEUKIN 2 RECEPTOR; RECOMBINANT INTERLEUKIN 10;

EID: 0041735102     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(03)01869-4     Document Type: Review
Times cited : (189)

References (83)
  • 1
    • 0024353079 scopus 로고
    • Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
    • (1989) Annu Rev Immunol , vol.7 , pp. 145-173
    • Mosmann, T.R.1    Coffman, R.L.2
  • 3
    • 0032968706 scopus 로고    scopus 로고
    • Immunologic basis of antigen-induced airway hyperresponsiveness
    • Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999;17:255-81.
    • (1999) Annu Rev Immunol , vol.17 , pp. 255-281
    • Wills-Karp, M.1
  • 5
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med 1988;168:1675-84.
    • (1988) J Exp Med , vol.168 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 7
    • 0027443372 scopus 로고
    • Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
    • Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178:2123-30.
    • (1993) J Exp Med , vol.178 , pp. 2123-2130
    • Secrist, H.1    Chelen, C.J.2    Wen, Y.3    Marshall, J.D.4    Umetsu, D.T.5
  • 8
    • 0027222095 scopus 로고
    • Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
    • Varney VA, Hamid QA, Gaga M, Ying S, Jacobson M, Frew AJ, et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92:644-51.
    • (1993) J Clin Invest , vol.92 , pp. 644-651
    • Varney, V.A.1    Hamid, Q.A.2    Gaga, M.3    Ying, S.4    Jacobson, M.5    Frew, A.J.6
  • 9
    • 0028901793 scopus 로고
    • Bee venom immunothempy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures
    • Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunothempy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures. J Immunol 1995;154:4187-94.
    • (1995) J Immunol , vol.154 , pp. 4187-4194
    • Jutel, M.1    Pichler, W.J.2    Skrbic, D.3    Urwyler, A.4    Dahinden, C.5    Muller, U.R.6
  • 10
    • 0029664297 scopus 로고    scopus 로고
    • Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
    • Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman R, et al. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A 1996;93:5141-5.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5141-5145
    • Raz, E.1    Tighe, H.2    Sato, Y.3    Corr, M.4    Dudler, J.A.5    Roman, R.6
  • 11
    • 0029925502 scopus 로고    scopus 로고
    • Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
    • Hsu CH, Chua KY, Tao MH, Lai YL, Wu HD, Huang SK, et al. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nat Med 1996;2:540-4.
    • (1996) Nat Med , vol.2 , pp. 540-544
    • Hsu, C.H.1    Chua, K.Y.2    Tao, M.H.3    Lai, Y.L.4    Wu, H.D.5    Huang, S.K.6
  • 12
    • 0031134912 scopus 로고    scopus 로고
    • An OVA-IL-12 fusion protein is more effective than OVA plus rIL-12 in inducing a Th1-dominated immune response and inhibiting antigen-specific IgE production
    • Kim TS, DeKruyff RH, Rupper R, Maecker HT, Levy S, Umetsu DT. An OVA-IL-12 fusion protein is more effective than OVA plus rIL-12 in inducing a Th1-dominated immune response and inhibiting antigen-specific IgE production. J Immunol 1997;158:4137-44.
    • (1997) J Immunol , vol.158 , pp. 4137-4144
    • Kim, T.S.1    DeKruyff, R.H.2    Rupper, R.3    Maecker, H.T.4    Levy, S.5    Umetsu, D.T.6
  • 13
    • 0032532606 scopus 로고    scopus 로고
    • Heat killed Listeria monocytogenes as an adjuvant converts established Th2dominated immune responses into Th1-dominated responses
    • Yeung VP, Gieni RS, Umetsu DT, DeKruyff RH. Heat killed Listeria monocytogenes as an adjuvant converts established Th2dominated immune responses into Th1-dominated responses. J Immunol 1998;161:4146-52.
    • (1998) J Immunol , vol.161 , pp. 4146-4152
    • Yeung, V.P.1    Gieni, R.S.2    Umetsu, D.T.3    DeKruyff, R.H.4
  • 14
    • 0028821825 scopus 로고
    • Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
    • Gavett SH, O'Hearn DJ, Li X, Huang S-K, Finkelman FD, Wills-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-36.
    • (1995) J Exp Med , vol.182 , pp. 1527-1536
    • Gavett, S.H.1    O'Hearn, D.J.2    Li, X.3    Huang, S.-K.4    Finkelman, F.D.5    Wills-Karp, M.6
  • 15
    • 0035863822 scopus 로고    scopus 로고
    • Vaccination with allergen-IL-18 fusion DNA protects against and reverses airway hyperreactivity in a murine asthma model: Dependence on interferon-γ and CD8 cells
    • Maecker HT, Hansen G, Walter D, DeKruyff RH, Levy S, Umetsu DT. Vaccination with allergen-IL-18 fusion DNA protects against and reverses airway hyperreactivity in a murine asthma model: dependence on interferon-γ and CD8 cells. J Immunol 2001:166:959-65.
    • (2001) J Immunol , vol.166 , pp. 959-965
    • Maecker, H.T.1    Hansen, G.2    Walter, D.3    DeKruyff, R.H.4    Levy, S.5    Umetsu, D.T.6
  • 16
    • 0035873683 scopus 로고    scopus 로고
    • IL-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity
    • Walter DM, Wong CP, DeKruyff RH, Berry GJ, Levy S, Umetsu DT. IL-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity. J Immunol 2001;166:6392-8.
    • (2001) J Immunol , vol.166 , pp. 6392-6398
    • Walter, D.M.1    Wong, C.P.2    DeKruyff, R.H.3    Berry, G.J.4    Levy, S.5    Umetsu, D.T.6
  • 17
    • 0028169324 scopus 로고
    • Reduced interferon-gamma secretion in neonates and subsequent atopy
    • Tang ML, Kemp AS, Thorburn J, Hill DJ. Reduced interferon-gamma secretion in neonates and subsequent atopy. Lancet 1994;344:983-5.
    • (1994) Lancet , vol.344 , pp. 983-985
    • Tang, M.L.1    Kemp, A.S.2    Thorburn, J.3    Hill, D.J.4
  • 18
    • 0030013507 scopus 로고    scopus 로고
    • Regulation of disease susceptibility: Decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis
    • Oro AS, Guarino TJ, Driver R, Steinman L, Umetsu DT. Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis. J Allergy Clin Immunol 1996;97:1402-8.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 1402-1408
    • Oro, A.S.1    Guarino, T.J.2    Driver, R.3    Steinman, L.4    Umetsu, D.T.5
  • 19
    • 0032945548 scopus 로고    scopus 로고
    • Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
    • Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999;103:175-83.
    • (1999) J Clin Invest , vol.103 , pp. 175-183
    • Hansen, G.1    Berry, G.2    DeKruyff, R.H.3    Umetsu, D.T.4
  • 20
    • 0033557718 scopus 로고    scopus 로고
    • Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
    • Randolph DA, Carruthers CJ, Szabo SJ, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999;162:2375-83.
    • (1999) J Immunol , vol.162 , pp. 2375-2383
    • Randolph, D.A.1    Carruthers, C.J.2    Szabo, S.J.3    Murphy, K.M.4    Chaplin, D.D.5
  • 21
    • 0028037782 scopus 로고
    • Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
    • Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-40.
    • (1994) Science , vol.265 , pp. 1237-1240
    • Chen, Y.1    Kuchroo, V.K.2    Inobe, J.3    Hafler, D.A.4    Weiner, H.L.5
  • 22
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997;389:737-42.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Antonenko, S.5    De Vries, J.E.6
  • 23
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25)
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). J Immunol 1995;160:1151-64.
    • (1995) J Immunol , vol.160 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 24
    • 0028179230 scopus 로고
    • Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
    • Powrie F, Correa-Oliveira R, Mauze S, Coffman R. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med 1994;179:589-600.
    • (1994) J Exp Med , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.4
  • 25
    • 0036170938 scopus 로고    scopus 로고
    • Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
    • Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002;3:135-42.
    • (2002) Nat Immunol , vol.3 , pp. 135-142
    • Shimizu, J.1    Yamazaki, S.2    Takahashi, T.3    Ishida, Y.4    Sakaguchi, S.5
  • 26
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-61.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 27
    • 0034526617 scopus 로고    scopus 로고
    • JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
    • Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000;106:R75-81.
    • (2000) J Clin Invest , vol.106
    • Chatila, T.A.1    Blaeser, F.2    Ho, N.3    Lederman, H.M.4    Voulgaropoulos, C.5    Helms, C.6
  • 28
    • 0035162560 scopus 로고    scopus 로고
    • Disruption of a new forkhead/winged-helix protein, scurtin, results in the fatal lymphoproliferative disorder of the scurfy mouse
    • Brunkow M, Jeffery E, Hjerrild K, Paeper B, Clark L, Yasayko S, et al. Disruption of a new forkhead/winged-helix protein, scurtin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001;27:68-73.
    • (2001) Nat Genet , vol.27 , pp. 68-73
    • Brunkow, M.1    Jeffery, E.2    Hjerrild, K.3    Paeper, B.4    Clark, L.5    Yasayko, S.6
  • 29
    • 0037097503 scopus 로고    scopus 로고
    • Cutting edge: Depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
    • McHugh RS, Shevach EM. Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J Immunol 2002;168:5979-83.
    • (2002) J Immunol , vol.168 , pp. 5979-5983
    • McHugh, R.S.1    Shevach, E.M.2
  • 30
    • 0035320679 scopus 로고    scopus 로고
    • Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
    • Jordan M, Boesteanu A, Reed A, Petrone A, Holenbeck A, Lerman M, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-6.
    • (2001) Nat Immunol , vol.2 , pp. 301-306
    • Jordan, M.1    Boesteanu, A.2    Reed, A.3    Petrone, A.4    Holenbeck, A.5    Lerman, M.6
  • 31
    • 0037450727 scopus 로고    scopus 로고
    • T cell regulation as a side effect of homeostasis and competition
    • Barthlott T, Kassiotis G, Stockinger B. T cell regulation as a side effect of homeostasis and competition. J Exp Med 2003;197:451-60.
    • (2003) J Exp Med , vol.197 , pp. 451-460
    • Barthlott, T.1    Kassiotis, G.2    Stockinger, B.3
  • 32
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003;299:1033-6.
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 34
    • 0035807302 scopus 로고    scopus 로고
    • A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
    • Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001;413:531-4.
    • (2001) Nature , vol.413 , pp. 531-534
    • Miyamoto, K.1    Miyake, S.2    Yamamura, T.3
  • 35
    • 0036850908 scopus 로고    scopus 로고
    • Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
    • Heller F, Fuss I, Nieuwenhuis E, Blumberg R, Strober W. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002;17:629-38.
    • (2002) Immunity , vol.17 , pp. 629-638
    • Heller, F.1    Fuss, I.2    Nieuwenhuis, E.3    Blumberg, R.4    Strober, W.5
  • 36
    • 0034569025 scopus 로고    scopus 로고
    • NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
    • Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson D, et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol 2000;1:515-20.
    • (2000) Nat Immunol , vol.1 , pp. 515-520
    • Terabe, M.1    Matsui, S.2    Noben-Trauth, N.3    Chen, H.4    Watson, C.5    Donaldson, D.6
  • 37
    • 0032547849 scopus 로고    scopus 로고
    • CDld-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
    • Brossay L, Chioda M, Burdin N, Koezuka Y, Casorati G, Dellabona P, et al. CDld-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 1998;188:1521-8.
    • (1998) J Exp Med , vol.188 , pp. 1521-1528
    • Brossay, L.1    Chioda, M.2    Burdin, N.3    Koezuka, Y.4    Casorati, G.5    Dellabona, P.6
  • 38
    • 0035835981 scopus 로고    scopus 로고
    • Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: A population-based cross-sectional study
    • Platts-Mills T, Vaughan J, Squillace S, Woodfolk J, Sporik R. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 2001;357:752-6.
    • (2001) Lancet , vol.357 , pp. 752-756
    • Platts-Mills, T.1    Vaughan, J.2    Squillace, S.3    Woodfolk, J.4    Sporik, R.5
  • 39
    • 0037190086 scopus 로고    scopus 로고
    • Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age
    • Ownby D, Johnson C, Peterson E. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 2002;288:963-72.
    • (2002) JAMA , vol.288 , pp. 963-972
    • Ownby, D.1    Johnson, C.2    Peterson, E.3
  • 40
    • 0032927086 scopus 로고    scopus 로고
    • Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community. SCARPOL team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution
    • Braun-Fahrlander C, Gassner M, Grize L, Neu U, Sennhauser FH, Varonier HS, et al. Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community. SCARPOL team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution. Clin Exp Allergy 1999;29:28-34.
    • (1999) Clin Exp Allergy , vol.29 , pp. 28-34
    • Braun-Fahrlander, C.1    Gassner, M.2    Grize, L.3    Neu, U.4    Sennhauser, F.H.5    Varonier, H.S.6
  • 41
    • 0033962806 scopus 로고    scopus 로고
    • Austrian children living on a farm have less hay fever, asthma and allergic sensitization
    • Riedler J, Eder W, Oberfeld G, Schreuer M. Austrian children living on a farm have less hay fever, asthma and allergic sensitization. Clin Exp Allergy 2000;30:194-200.
    • (2000) Clin Exp Allergy , vol.30 , pp. 194-200
    • Riedler, J.1    Eder, W.2    Oberfeld, G.3    Schreuer, M.4
  • 42
    • 0034110846 scopus 로고    scopus 로고
    • Relative scarcity of asthma and atopy among rural adolescents raised on a farm
    • Ernst P, Cormier Y. Relative scarcity of asthma and atopy among rural adolescents raised on a farm. Am J Respir Cfit Care Med 2000;161:1563-6.
    • (2000) Am J Respir Cfit Care Med , vol.161 , pp. 1563-1566
    • Ernst, P.1    Cormier, Y.2
  • 43
    • 0037136585 scopus 로고    scopus 로고
    • Environmental exposure to endotoxin and its relation to asthma in school-age children
    • Braun-Fahrlander C, Riedler J, Herz U, Eder W, Waser M, Grize L, et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-77.
    • (2002) N Engl J Med , vol.347 , pp. 869-877
    • Braun-Fahrlander, C.1    Riedler, J.2    Herz, U.3    Eder, W.4    Waser, M.5    Grize, L.6
  • 44
    • 0002691620 scopus 로고    scopus 로고
    • CD4+ Th cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation
    • Hansen G, McIntire JJ, Yeung VP, Berry G, Thorbecke GJ, Chen L, et al. CD4+ Th cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J Clin Invest 2000;11:89-96.
    • (2000) J Clin Invest , vol.11 , pp. 89-96
    • Hansen, G.1    McIntire, J.J.2    Yeung, V.P.3    Berry, G.4    Thorbecke, G.J.5    Chen, L.6
  • 45
    • 0034679703 scopus 로고    scopus 로고
    • Blockade of transforming growth factor β/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity
    • Nakao A, Miike S, Hatano M, Okumura K, Tokuhisa T, Ra C, et al. Blockade of transforming growth factor β/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity. J Exp Med 2000;192:151-8.
    • (2000) J Exp Med , vol.192 , pp. 151-158
    • Nakao, A.1    Miike, S.2    Hatano, M.3    Okumura, K.4    Tokuhisa, T.5    Ra, C.6
  • 46
    • 0036736840 scopus 로고    scopus 로고
    • CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hyperreactivity and inflammation
    • Oh JW, Seroogy CM, Meyer EH, Akbari O, Berry G, Fathman CG, et al. CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hyperreactivity and inflammation. J Allergy Clin Immunol 2002;110:460-8.
    • (2002) J Allergy Clin Immunol , vol.110 , pp. 460-468
    • Oh, J.W.1    Seroogy, C.M.2    Meyer, E.H.3    Akbari, O.4    Berry, G.5    Fathman, C.G.6
  • 48
    • 0031055406 scopus 로고    scopus 로고
    • Oral tolerance for the treatment of autoimmune diseases
    • Weiner HL. Oral tolerance for the treatment of autoimmune diseases. Annu Rev Med 1997;48:341-51.
    • (1997) Annu Rev Med , vol.48 , pp. 341-351
    • Weiner, H.L.1
  • 49
    • 0027451437 scopus 로고
    • Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
    • Hoyne GF, O'Hehir RE, Wraith DC, Thomas WR, Lamb JR. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J Exp Med 1993;178:1783-8.
    • (1993) J Exp Med , vol.178 , pp. 1783-1788
    • Hoyne, G.F.1    O'Hehir, R.E.2    Wraith, D.C.3    Thomas, W.R.4    Lamb, J.R.5
  • 50
    • 0033198184 scopus 로고    scopus 로고
    • Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells
    • Tsitoura DC, DeKruyff RH, Lamb JR, Umetsu DT. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J Immunol 1999;163:2592-600.
    • (1999) J Immunol , vol.163 , pp. 2592-2600
    • Tsitoura, D.C.1    DeKruyff, R.H.2    Lamb, J.R.3    Umetsu, D.T.4
  • 51
    • 0032473551 scopus 로고    scopus 로고
    • Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization
    • Seymour BW, Gershwin LJ, Coffman RL. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization. J Exp Meal 1998;187:721-31.
    • (1998) J Exp Meal , vol.187 , pp. 721-731
    • Seymour, B.W.1    Gershwin, L.J.2    Coffman, R.L.3
  • 52
    • 0027993367 scopus 로고
    • Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells
    • McMenamin C, Pimm C, McKersey M, Holt PG. Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells. Science 1994;265:1869-71.
    • (1994) Science , vol.265 , pp. 1869-1871
    • McMenamin, C.1    Pimm, C.2    McKersey, M.3    Holt, P.G.4
  • 53
    • 0027169803 scopus 로고
    • The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production
    • McMenamin C, Holt PG. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J Exp Med 1993;178:889-99.
    • (1993) J Exp Med , vol.178 , pp. 889-899
    • McMenamin, C.1    Holt, P.G.2
  • 54
    • 0032846597 scopus 로고    scopus 로고
    • Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells
    • Lahn M, Kanehiro A, Takeda K, Joetham A, Schwarze J, Kohler G, et al. Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells. Nat Med 1999;5:1150-6.
    • (1999) Nat Med , vol.5 , pp. 1150-1156
    • Lahn, M.1    Kanehiro, A.2    Takeda, K.3    Joetham, A.4    Schwarze, J.5    Kohler, G.6
  • 56
    • 0033120971 scopus 로고    scopus 로고
    • CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness
    • Schwarze J, Cieslewicz G, Joetham A, Ikemura T, Hamelmann E, Gelfand EW. CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness. J Immunol 1999;162:4207-11.
    • (1999) J Immunol , vol.162 , pp. 4207-4211
    • Schwarze, J.1    Cieslewicz, G.2    Joetham, A.3    Ikemura, T.4    Hamelmann, E.5    Gelfand, E.W.6
  • 57
    • 0030068998 scopus 로고    scopus 로고
    • Regulation of house dust mite responses by intranasally administered peptide: Transient activation of CD4+ T cells precedes the development of tolerance in vivo
    • Hoyne GF, Askonas BA, Hetzel C, Thomas WR, Lamb JR. Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo. Int Immunol 1996;8:335-42.
    • (1996) Int Immunol , vol.8 , pp. 335-342
    • Hoyne, G.F.1    Askonas, B.A.2    Hetzel, C.3    Thomas, W.R.4    Lamb, J.R.5
  • 59
    • 0033845105 scopus 로고    scopus 로고
    • Mechanisms preventing allergen-induced airways hyperreactivity: Role of immune deviation and tolerance
    • Tsitoura DC, Blumenthal RL, Berry G, DeKruyff RH, Umetsu DT. Mechanisms preventing allergen-induced airways hyperreactivity: Role of immune deviation and tolerance. J Allergy Clin Immunol 2000;106:239-46.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 239-246
    • Tsitoura, D.C.1    Blumenthal, R.L.2    Berry, G.3    DeKruyff, R.H.4    Umetsu, D.T.5
  • 60
    • 0034890907 scopus 로고    scopus 로고
    • Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen
    • Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen. Nat Immunol 2001;2:725-31.
    • (2001) Nat Immunol , vol.2 , pp. 725-731
    • Akbari, O.1    DeKruyff, R.H.2    Umetsu, D.T.3
  • 61
    • 0035903326 scopus 로고    scopus 로고
    • Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
    • Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001;194:769-79.
    • (2001) J Exp Med , vol.194 , pp. 769-779
    • Hawiger, D.1    Inaba, K.2    Dorsett, Y.3    Guo, M.4    Mahnke, K.5    Rivera, M.6
  • 62
    • 0035862333 scopus 로고    scopus 로고
    • Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
    • Dhodapkar M, Steinman R, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med 2001;193:233-8.
    • (2001) J Exp Med , vol.193 , pp. 233-238
    • Dhodapkar, M.1    Steinman, R.2    Krasovsky, J.3    Munz, C.4    Bhardwaj, N.5
  • 65
    • 0035804254 scopus 로고    scopus 로고
    • ICOS co-stimulatory receptor is essential for T-cell activation and function
    • Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, Ruddle NH, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101.
    • (2001) Nature , vol.409 , pp. 97-101
    • Dong, C.1    Juedes, A.E.2    Temann, U.A.3    Shresta, S.4    Allison, J.P.5    Ruddle, N.H.6
  • 67
    • 0037340349 scopus 로고    scopus 로고
    • Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
    • Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Drager R, et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol 2003;4:261-8.
    • (2003) Nat Immunol , vol.4 , pp. 261-268
    • Grimbacher, B.1    Hutloff, A.2    Schlesier, M.3    Glocker, E.4    Warnatz, K.5    Drager, R.6
  • 68
    • 0037911660 scopus 로고    scopus 로고
    • Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
    • Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med 2003;9:582-8.
    • (2003) Nat Med , vol.9 , pp. 582-588
    • Akbari, O.1    Stock, P.2    Meyer, E.3    Kronenberg, M.4    Sidobre, S.5    Nakayama, T.6
  • 69
    • 0031028170 scopus 로고    scopus 로고
    • Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
    • Smiley ST, Kaplan MH, Grusby MJ. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science 1997;275:977-9.
    • (1997) Science , vol.275 , pp. 977-979
    • Smiley, S.T.1    Kaplan, M.H.2    Grusby, M.J.3
  • 70
    • 0029959243 scopus 로고    scopus 로고
    • Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses
    • Brown D, Fowell D, Corry D, Wynn T, Moskowitz N, Cheever A, et al. Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med 1996;184:1295-304.
    • (1996) J Exp Med , vol.184 , pp. 1295-1304
    • Brown, D.1    Fowell, D.2    Corry, D.3    Wynn, T.4    Moskowitz, N.5    Cheever, A.6
  • 71
    • 0034885046 scopus 로고    scopus 로고
    • The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells
    • Weiner HL. The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells. Nat Immunol 2001;2:671-2.
    • (2001) Nat Immunol , vol.2 , pp. 671-672
    • Weiner, H.L.1
  • 72
    • 0034327264 scopus 로고    scopus 로고
    • T regulatory cells 1 inhibit a Th2-specific response in vivo
    • Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000;165:4848-53.
    • (2000) J Immunol , vol.165 , pp. 4848-4853
    • Cottrez, F.1    Hurst, S.D.2    Coffman, R.L.3    Groux, H.4
  • 73
    • 0036732461 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
    • Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002;8:1024-32.
    • (2002) Nat Med , vol.8 , pp. 1024-1032
    • Akbari, O.1    Freeman, G.J.2    Meyer, E.H.3    Greenfield, E.A.4    Chang, T.T.5    Sharpe, A.H.6
  • 74
    • 0035881129 scopus 로고    scopus 로고
    • Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways
    • Suto A, Nakajima H, Kagami S, Suzuki K, Saito Y, Iwamoto I. Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways. Am J Respir Crit Care Med 2001;164:680-7.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 680-687
    • Suto, A.1    Nakajima, H.2    Kagami, S.3    Suzuki, K.4    Saito, Y.5    Iwamoto, I.6
  • 75
    • 0037514382 scopus 로고    scopus 로고
    • Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity
    • Hadeiba H, Locksley R. Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity. J Immunol 2003;170:5502-10.
    • (2003) J Immunol , vol.170 , pp. 5502-5510
    • Hadeiba, H.1    Locksley, R.2
  • 76
    • 0019984839 scopus 로고
    • Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction
    • Wannemuehler MJ, Kiyono H, Babb JL, Michalek SM, McGhee JR. Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction. J Immunol 1982;129:959-65.
    • (1982) J Immunol , vol.129 , pp. 959-965
    • Wannemuehler, M.J.1    Kiyono, H.2    Babb, J.L.3    Michalek, S.M.4    McGhee, J.R.5
  • 77
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
    • Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 1997;159:1739-45.
    • (1997) J Immunol , vol.159 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.2    Tanaka, K.3    Aiba, Y.4    Kubo, C.5    Koga, Y.6
  • 78
    • 0035204919 scopus 로고    scopus 로고
    • Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
    • McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2001;2:1109-16.
    • (2001) Nat Immunol , vol.2 , pp. 1109-1116
    • McIntire, J.J.1    Umetsu, S.E.2    Akbari, O.3    Potter, M.4    Kuchroo, V.K.5    Barsh, G.S.6
  • 79
    • 0034639769 scopus 로고    scopus 로고
    • Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: Epidemiological study
    • Matricardi P, Rosmini F, Riondino S, Fortini M, Ferrigno L, Rapicetta M, et al. Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study. BMJ 2000;320:412-7.
    • (2000) BMJ , vol.320 , pp. 412-417
    • Matricardi, P.1    Rosmini, F.2    Riondino, S.3    Fortini, M.4    Ferrigno, L.5    Rapicetta, M.6
  • 81
    • 0037136537 scopus 로고    scopus 로고
    • The effect of infections on susceptibility to autoimmune and allergic diseases
    • Bach J. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002;347:911-20.
    • (2002) N Engl J Med , vol.347 , pp. 911-920
    • Bach, J.1
  • 82
    • 0031903498 scopus 로고    scopus 로고
    • The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor
    • Feigelstock D, Thompson P, Mattoo P, Zhang Y, Kaplan GG. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J Virol 1998;72:6621-8.
    • (1998) J Virol , vol.72 , pp. 6621-6628
    • Feigelstock, D.1    Thompson, P.2    Mattoo, P.3    Zhang, Y.4    Kaplan, G.G.5


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