-
1
-
-
0024353079
-
Th1 and Th2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann TR, Coffman RL. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-73.
-
(1989)
Annu Rev Immunol
, vol.7
, pp. 145-173
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
2
-
-
0023803978
-
Functional heterogeneity among human inducer T cell clones
-
Umetsu DT, Jabara HH, DeKruyff RH, Abbas AK, Abrams JS, Geha RS. Functional heterogeneity among human inducer T cell clones. J Immunol 1988;140:4211-6.
-
(1988)
J Immunol
, vol.140
, pp. 4211-4216
-
-
Umetsu, D.T.1
Jabara, H.H.2
DeKruyff, R.H.3
Abbas, A.K.4
Abrams, J.S.5
Geha, R.S.6
-
3
-
-
0032968706
-
Immunologic basis of antigen-induced airway hyperresponsiveness
-
Wills-Karp M. Immunologic basis of antigen-induced airway hyperresponsiveness. Annu Rev Immunol 1999;17:255-81.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 255-281
-
-
Wills-Karp, M.1
-
4
-
-
0029092934
-
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products
-
Busse WW, Coffman RL, Gelfand EW, Kay AB, Rosenwasser LJ. Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products. Am J Respir Crit Care Med 1995;152:388-93.
-
(1995)
Am J Respir Crit Care Med
, vol.152
, pp. 388-393
-
-
Busse, W.W.1
Coffman, R.L.2
Gelfand, E.W.3
Kay, A.B.4
Rosenwasser, L.J.5
-
5
-
-
0024236111
-
Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
-
Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med 1988;168:1675-84.
-
(1988)
J Exp Med
, vol.168
, pp. 1675-1684
-
-
Scott, P.1
Natovitz, P.2
Coffman, R.L.3
Pearce, E.4
Sher, A.5
-
6
-
-
0026079543
-
Human atopen-specific types 1 and 2 T helper cell clones
-
Wierenga EA, Snoek M, Jansen HM, Bos JD, van Lier RAW, Kapsenberg ML. Human atopen-specific types 1 and 2 T helper cell clones. J Immunol 1991;147:2942-9.
-
(1991)
J Immunol
, vol.147
, pp. 2942-2949
-
-
Wierenga, E.A.1
Snoek, M.2
Jansen, H.M.3
Bos, J.D.4
Van Lier, R.A.W.5
Kapsenberg, M.L.6
-
7
-
-
0027443372
-
Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals
-
Secrist H, Chelen CJ, Wen Y, Marshall JD, Umetsu DT. Allergen immunotherapy decreases interleukin 4 production in CD4+ T cells from allergic individuals. J Exp Med 1993;178:2123-30.
-
(1993)
J Exp Med
, vol.178
, pp. 2123-2130
-
-
Secrist, H.1
Chelen, C.J.2
Wen, Y.3
Marshall, J.D.4
Umetsu, D.T.5
-
8
-
-
0027222095
-
Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses
-
Varney VA, Hamid QA, Gaga M, Ying S, Jacobson M, Frew AJ, et al. Influence of grass pollen immunotherapy on cellular infiltration and cytokine mRNA expression during allergen-induced late-phase cutaneous responses. J Clin Invest 1993;92:644-51.
-
(1993)
J Clin Invest
, vol.92
, pp. 644-651
-
-
Varney, V.A.1
Hamid, Q.A.2
Gaga, M.3
Ying, S.4
Jacobson, M.5
Frew, A.J.6
-
9
-
-
0028901793
-
Bee venom immunothempy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures
-
Jutel M, Pichler WJ, Skrbic D, Urwyler A, Dahinden C, Muller UR. Bee venom immunothempy results in decrease of IL-4 and IL-5 and increase of IFN-gamma secretion in specific allergen-stimulated T cell cultures. J Immunol 1995;154:4187-94.
-
(1995)
J Immunol
, vol.154
, pp. 4187-4194
-
-
Jutel, M.1
Pichler, W.J.2
Skrbic, D.3
Urwyler, A.4
Dahinden, C.5
Muller, U.R.6
-
10
-
-
0029664297
-
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
-
Raz E, Tighe H, Sato Y, Corr M, Dudler JA, Roman R, et al. Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization. Proc Natl Acad Sci U S A 1996;93:5141-5.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 5141-5145
-
-
Raz, E.1
Tighe, H.2
Sato, Y.3
Corr, M.4
Dudler, J.A.5
Roman, R.6
-
11
-
-
0029925502
-
Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
-
Hsu CH, Chua KY, Tao MH, Lai YL, Wu HD, Huang SK, et al. Immunoprophylaxis of allergen-induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization. Nat Med 1996;2:540-4.
-
(1996)
Nat Med
, vol.2
, pp. 540-544
-
-
Hsu, C.H.1
Chua, K.Y.2
Tao, M.H.3
Lai, Y.L.4
Wu, H.D.5
Huang, S.K.6
-
12
-
-
0031134912
-
An OVA-IL-12 fusion protein is more effective than OVA plus rIL-12 in inducing a Th1-dominated immune response and inhibiting antigen-specific IgE production
-
Kim TS, DeKruyff RH, Rupper R, Maecker HT, Levy S, Umetsu DT. An OVA-IL-12 fusion protein is more effective than OVA plus rIL-12 in inducing a Th1-dominated immune response and inhibiting antigen-specific IgE production. J Immunol 1997;158:4137-44.
-
(1997)
J Immunol
, vol.158
, pp. 4137-4144
-
-
Kim, T.S.1
DeKruyff, R.H.2
Rupper, R.3
Maecker, H.T.4
Levy, S.5
Umetsu, D.T.6
-
13
-
-
0032532606
-
Heat killed Listeria monocytogenes as an adjuvant converts established Th2dominated immune responses into Th1-dominated responses
-
Yeung VP, Gieni RS, Umetsu DT, DeKruyff RH. Heat killed Listeria monocytogenes as an adjuvant converts established Th2dominated immune responses into Th1-dominated responses. J Immunol 1998;161:4146-52.
-
(1998)
J Immunol
, vol.161
, pp. 4146-4152
-
-
Yeung, V.P.1
Gieni, R.S.2
Umetsu, D.T.3
DeKruyff, R.H.4
-
14
-
-
0028821825
-
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice
-
Gavett SH, O'Hearn DJ, Li X, Huang S-K, Finkelman FD, Wills-Karp M. Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-36.
-
(1995)
J Exp Med
, vol.182
, pp. 1527-1536
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Li, X.3
Huang, S.-K.4
Finkelman, F.D.5
Wills-Karp, M.6
-
15
-
-
0035863822
-
Vaccination with allergen-IL-18 fusion DNA protects against and reverses airway hyperreactivity in a murine asthma model: Dependence on interferon-γ and CD8 cells
-
Maecker HT, Hansen G, Walter D, DeKruyff RH, Levy S, Umetsu DT. Vaccination with allergen-IL-18 fusion DNA protects against and reverses airway hyperreactivity in a murine asthma model: dependence on interferon-γ and CD8 cells. J Immunol 2001:166:959-65.
-
(2001)
J Immunol
, vol.166
, pp. 959-965
-
-
Maecker, H.T.1
Hansen, G.2
Walter, D.3
DeKruyff, R.H.4
Levy, S.5
Umetsu, D.T.6
-
16
-
-
0035873683
-
IL-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity
-
Walter DM, Wong CP, DeKruyff RH, Berry GJ, Levy S, Umetsu DT. IL-18 gene transfer by adenovirus prevents the development of and reverses established allergen-induced airway hyperreactivity. J Immunol 2001;166:6392-8.
-
(2001)
J Immunol
, vol.166
, pp. 6392-6398
-
-
Walter, D.M.1
Wong, C.P.2
DeKruyff, R.H.3
Berry, G.J.4
Levy, S.5
Umetsu, D.T.6
-
17
-
-
0028169324
-
Reduced interferon-gamma secretion in neonates and subsequent atopy
-
Tang ML, Kemp AS, Thorburn J, Hill DJ. Reduced interferon-gamma secretion in neonates and subsequent atopy. Lancet 1994;344:983-5.
-
(1994)
Lancet
, vol.344
, pp. 983-985
-
-
Tang, M.L.1
Kemp, A.S.2
Thorburn, J.3
Hill, D.J.4
-
18
-
-
0030013507
-
Regulation of disease susceptibility: Decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis
-
Oro AS, Guarino TJ, Driver R, Steinman L, Umetsu DT. Regulation of disease susceptibility: decreased prevalence of IgE-mediated allergic disease in patients with multiple sclerosis. J Allergy Clin Immunol 1996;97:1402-8.
-
(1996)
J Allergy Clin Immunol
, vol.97
, pp. 1402-1408
-
-
Oro, A.S.1
Guarino, T.J.2
Driver, R.3
Steinman, L.4
Umetsu, D.T.5
-
19
-
-
0032945548
-
Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation
-
Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999;103:175-83.
-
(1999)
J Clin Invest
, vol.103
, pp. 175-183
-
-
Hansen, G.1
Berry, G.2
DeKruyff, R.H.3
Umetsu, D.T.4
-
20
-
-
0033557718
-
Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
-
Randolph DA, Carruthers CJ, Szabo SJ, Murphy KM, Chaplin DD. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J Immunol 1999;162:2375-83.
-
(1999)
J Immunol
, vol.162
, pp. 2375-2383
-
-
Randolph, D.A.1
Carruthers, C.J.2
Szabo, S.J.3
Murphy, K.M.4
Chaplin, D.D.5
-
21
-
-
0028037782
-
Regulatory T cell clones induced by oral tolerance: Suppression of autoimmune encephalomyelitis
-
Chen Y, Kuchroo VK, Inobe J, Hafler DA, Weiner HL. Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis. Science 1994;265:1237-40.
-
(1994)
Science
, vol.265
, pp. 1237-1240
-
-
Chen, Y.1
Kuchroo, V.K.2
Inobe, J.3
Hafler, D.A.4
Weiner, H.L.5
-
22
-
-
0030704726
-
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
-
Groux H, O'Garra A, Bigler M, Rouleau M, Antonenko S, de Vries JE, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997;389:737-42.
-
(1997)
Nature
, vol.389
, pp. 737-742
-
-
Groux, H.1
O'Garra, A.2
Bigler, M.3
Rouleau, M.4
Antonenko, S.5
De Vries, J.E.6
-
23
-
-
0029150110
-
Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25)
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). J Immunol 1995;160:1151-64.
-
(1995)
J Immunol
, vol.160
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
24
-
-
0028179230
-
Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
-
Powrie F, Correa-Oliveira R, Mauze S, Coffman R. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J Exp Med 1994;179:589-600.
-
(1994)
J Exp Med
, vol.179
, pp. 589-600
-
-
Powrie, F.1
Correa-Oliveira, R.2
Mauze, S.3
Coffman, R.4
-
25
-
-
0036170938
-
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance
-
Shimizu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002;3:135-42.
-
(2002)
Nat Immunol
, vol.3
, pp. 135-142
-
-
Shimizu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
26
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003;299:1057-61.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
27
-
-
0034526617
-
JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome
-
Chatila TA, Blaeser F, Ho N, Lederman HM, Voulgaropoulos C, Helms C, et al. JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome. J Clin Invest 2000;106:R75-81.
-
(2000)
J Clin Invest
, vol.106
-
-
Chatila, T.A.1
Blaeser, F.2
Ho, N.3
Lederman, H.M.4
Voulgaropoulos, C.5
Helms, C.6
-
28
-
-
0035162560
-
Disruption of a new forkhead/winged-helix protein, scurtin, results in the fatal lymphoproliferative disorder of the scurfy mouse
-
Brunkow M, Jeffery E, Hjerrild K, Paeper B, Clark L, Yasayko S, et al. Disruption of a new forkhead/winged-helix protein, scurtin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet 2001;27:68-73.
-
(2001)
Nat Genet
, vol.27
, pp. 68-73
-
-
Brunkow, M.1
Jeffery, E.2
Hjerrild, K.3
Paeper, B.4
Clark, L.5
Yasayko, S.6
-
29
-
-
0037097503
-
Cutting edge: Depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease
-
McHugh RS, Shevach EM. Cutting edge: depletion of CD4+CD25+ regulatory T cells is necessary, but not sufficient, for induction of organ-specific autoimmune disease. J Immunol 2002;168:5979-83.
-
(2002)
J Immunol
, vol.168
, pp. 5979-5983
-
-
McHugh, R.S.1
Shevach, E.M.2
-
30
-
-
0035320679
-
Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
-
Jordan M, Boesteanu A, Reed A, Petrone A, Holenbeck A, Lerman M, et al. Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide. Nat Immunol 2001;2:301-6.
-
(2001)
Nat Immunol
, vol.2
, pp. 301-306
-
-
Jordan, M.1
Boesteanu, A.2
Reed, A.3
Petrone, A.4
Holenbeck, A.5
Lerman, M.6
-
31
-
-
0037450727
-
T cell regulation as a side effect of homeostasis and competition
-
Barthlott T, Kassiotis G, Stockinger B. T cell regulation as a side effect of homeostasis and competition. J Exp Med 2003;197:451-60.
-
(2003)
J Exp Med
, vol.197
, pp. 451-460
-
-
Barthlott, T.1
Kassiotis, G.2
Stockinger, B.3
-
32
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
Pasare C, Medzhitov R. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science 2003;299:1033-6.
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
33
-
-
0032495536
-
Extreme Th1 bias of invariant V 24J Q T cells in type 1 diabetes
-
Wilson SB, Kent SC, Patton KT, Orban T, Jackson RA, Exley M, et al. Extreme Th1 bias of invariant V 24J Q T cells in type 1 diabetes. Nature 1998;391:177-81.
-
(1998)
Nature
, vol.391
, pp. 177-181
-
-
Wilson, S.B.1
Kent, S.C.2
Patton, K.T.3
Orban, T.4
Jackson, R.A.5
Exley, M.6
-
34
-
-
0035807302
-
A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells
-
Miyamoto K, Miyake S, Yamamura T. A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature 2001;413:531-4.
-
(2001)
Nature
, vol.413
, pp. 531-534
-
-
Miyamoto, K.1
Miyake, S.2
Yamamura, T.3
-
35
-
-
0036850908
-
Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells
-
Heller F, Fuss I, Nieuwenhuis E, Blumberg R, Strober W. Oxazolone colitis, a Th2 colitis model resembling ulcerative colitis, is mediated by IL-13-producing NK-T cells. Immunity 2002;17:629-38.
-
(2002)
Immunity
, vol.17
, pp. 629-638
-
-
Heller, F.1
Fuss, I.2
Nieuwenhuis, E.3
Blumberg, R.4
Strober, W.5
-
36
-
-
0034569025
-
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
-
Terabe M, Matsui S, Noben-Trauth N, Chen H, Watson C, Donaldson D, et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol 2000;1:515-20.
-
(2000)
Nat Immunol
, vol.1
, pp. 515-520
-
-
Terabe, M.1
Matsui, S.2
Noben-Trauth, N.3
Chen, H.4
Watson, C.5
Donaldson, D.6
-
37
-
-
0032547849
-
CDld-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
-
Brossay L, Chioda M, Burdin N, Koezuka Y, Casorati G, Dellabona P, et al. CDld-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 1998;188:1521-8.
-
(1998)
J Exp Med
, vol.188
, pp. 1521-1528
-
-
Brossay, L.1
Chioda, M.2
Burdin, N.3
Koezuka, Y.4
Casorati, G.5
Dellabona, P.6
-
38
-
-
0035835981
-
Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: A population-based cross-sectional study
-
Platts-Mills T, Vaughan J, Squillace S, Woodfolk J, Sporik R. Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study. Lancet 2001;357:752-6.
-
(2001)
Lancet
, vol.357
, pp. 752-756
-
-
Platts-Mills, T.1
Vaughan, J.2
Squillace, S.3
Woodfolk, J.4
Sporik, R.5
-
39
-
-
0037190086
-
Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age
-
Ownby D, Johnson C, Peterson E. Exposure to dogs and cats in the first year of life and risk of allergic sensitization at 6 to 7 years of age. JAMA 2002;288:963-72.
-
(2002)
JAMA
, vol.288
, pp. 963-972
-
-
Ownby, D.1
Johnson, C.2
Peterson, E.3
-
40
-
-
0032927086
-
Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community. SCARPOL team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution
-
Braun-Fahrlander C, Gassner M, Grize L, Neu U, Sennhauser FH, Varonier HS, et al. Prevalence of hay fever and allergic sensitization in farmer's children and their peers living in the same rural community. SCARPOL team. Swiss Study on Childhood Allergy and Respiratory Symptoms with Respect to Air Pollution. Clin Exp Allergy 1999;29:28-34.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 28-34
-
-
Braun-Fahrlander, C.1
Gassner, M.2
Grize, L.3
Neu, U.4
Sennhauser, F.H.5
Varonier, H.S.6
-
41
-
-
0033962806
-
Austrian children living on a farm have less hay fever, asthma and allergic sensitization
-
Riedler J, Eder W, Oberfeld G, Schreuer M. Austrian children living on a farm have less hay fever, asthma and allergic sensitization. Clin Exp Allergy 2000;30:194-200.
-
(2000)
Clin Exp Allergy
, vol.30
, pp. 194-200
-
-
Riedler, J.1
Eder, W.2
Oberfeld, G.3
Schreuer, M.4
-
42
-
-
0034110846
-
Relative scarcity of asthma and atopy among rural adolescents raised on a farm
-
Ernst P, Cormier Y. Relative scarcity of asthma and atopy among rural adolescents raised on a farm. Am J Respir Cfit Care Med 2000;161:1563-6.
-
(2000)
Am J Respir Cfit Care Med
, vol.161
, pp. 1563-1566
-
-
Ernst, P.1
Cormier, Y.2
-
43
-
-
0037136585
-
Environmental exposure to endotoxin and its relation to asthma in school-age children
-
Braun-Fahrlander C, Riedler J, Herz U, Eder W, Waser M, Grize L, et al. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-77.
-
(2002)
N Engl J Med
, vol.347
, pp. 869-877
-
-
Braun-Fahrlander, C.1
Riedler, J.2
Herz, U.3
Eder, W.4
Waser, M.5
Grize, L.6
-
44
-
-
0002691620
-
CD4+ Th cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation
-
Hansen G, McIntire JJ, Yeung VP, Berry G, Thorbecke GJ, Chen L, et al. CD4+ Th cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation. J Clin Invest 2000;11:89-96.
-
(2000)
J Clin Invest
, vol.11
, pp. 89-96
-
-
Hansen, G.1
McIntire, J.J.2
Yeung, V.P.3
Berry, G.4
Thorbecke, G.J.5
Chen, L.6
-
45
-
-
0034679703
-
Blockade of transforming growth factor β/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity
-
Nakao A, Miike S, Hatano M, Okumura K, Tokuhisa T, Ra C, et al. Blockade of transforming growth factor β/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity. J Exp Med 2000;192:151-8.
-
(2000)
J Exp Med
, vol.192
, pp. 151-158
-
-
Nakao, A.1
Miike, S.2
Hatano, M.3
Okumura, K.4
Tokuhisa, T.5
Ra, C.6
-
46
-
-
0036736840
-
CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hyperreactivity and inflammation
-
Oh JW, Seroogy CM, Meyer EH, Akbari O, Berry G, Fathman CG, et al. CD4 T helper cells engineered to produce IL-10 reverse allergen-induced airway hyperreactivity and inflammation. J Allergy Clin Immunol 2002;110:460-8.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 460-468
-
-
Oh, J.W.1
Seroogy, C.M.2
Meyer, E.H.3
Akbari, O.4
Berry, G.5
Fathman, C.G.6
-
47
-
-
0033219725
-
Interleukin-10 gene transfer to the airway regulates allegic mucosal sensitization in mice
-
Stampfli MR, Cwiartka M, Gajewska BU, Alverez D, Ritz SA, Inman MD, et al. Interleukin-10 gene transfer to the airway regulates allegic mucosal sensitization in mice. Am J Respir Cell Mol Biol 1999;21:586-96.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 586-596
-
-
Stampfli, M.R.1
Cwiartka, M.2
Gajewska, B.U.3
Alverez, D.4
Ritz, S.A.5
Inman, M.D.6
-
48
-
-
0031055406
-
Oral tolerance for the treatment of autoimmune diseases
-
Weiner HL. Oral tolerance for the treatment of autoimmune diseases. Annu Rev Med 1997;48:341-51.
-
(1997)
Annu Rev Med
, vol.48
, pp. 341-351
-
-
Weiner, H.L.1
-
49
-
-
0027451437
-
Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
-
Hoyne GF, O'Hehir RE, Wraith DC, Thomas WR, Lamb JR. Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J Exp Med 1993;178:1783-8.
-
(1993)
J Exp Med
, vol.178
, pp. 1783-1788
-
-
Hoyne, G.F.1
O'Hehir, R.E.2
Wraith, D.C.3
Thomas, W.R.4
Lamb, J.R.5
-
50
-
-
0033198184
-
Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells
-
Tsitoura DC, DeKruyff RH, Lamb JR, Umetsu DT. Intranasal exposure to protein antigen induces immunological tolerance mediated by functionally disabled CD4+ T cells. J Immunol 1999;163:2592-600.
-
(1999)
J Immunol
, vol.163
, pp. 2592-2600
-
-
Tsitoura, D.C.1
DeKruyff, R.H.2
Lamb, J.R.3
Umetsu, D.T.4
-
51
-
-
0032473551
-
Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization
-
Seymour BW, Gershwin LJ, Coffman RL. Aerosol-induced immunoglobulin (Ig)-E unresponsiveness to ovalbumin does not require CD8+ or T cell receptor (TCR)-gamma/delta+ T cells or interferon (IFN)-gamma in a murine model of allergen sensitization. J Exp Meal 1998;187:721-31.
-
(1998)
J Exp Meal
, vol.187
, pp. 721-731
-
-
Seymour, B.W.1
Gershwin, L.J.2
Coffman, R.L.3
-
52
-
-
0027993367
-
Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells
-
McMenamin C, Pimm C, McKersey M, Holt PG. Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells. Science 1994;265:1869-71.
-
(1994)
Science
, vol.265
, pp. 1869-1871
-
-
McMenamin, C.1
Pimm, C.2
McKersey, M.3
Holt, P.G.4
-
53
-
-
0027169803
-
The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production
-
McMenamin C, Holt PG. The natural immune response to inhaled soluble protein antigens involves major histocompatibility complex (MHC) class I-restricted CD8+ T cell-mediated but MHC class II-restricted CD4+ T cell-dependent immune deviation resulting in selective suppression of immunoglobulin E production. J Exp Med 1993;178:889-99.
-
(1993)
J Exp Med
, vol.178
, pp. 889-899
-
-
McMenamin, C.1
Holt, P.G.2
-
54
-
-
0032846597
-
Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells
-
Lahn M, Kanehiro A, Takeda K, Joetham A, Schwarze J, Kohler G, et al. Negative regulation of airway responsiveness that is dependent on gammadelta T cells and independent of alphabeta T cells. Nat Med 1999;5:1150-6.
-
(1999)
Nat Med
, vol.5
, pp. 1150-1156
-
-
Lahn, M.1
Kanehiro, A.2
Takeda, K.3
Joetham, A.4
Schwarze, J.5
Kohler, G.6
-
55
-
-
0032557246
-
Requirement for T cells in allergic airway inflammation
-
Zuany-Amorim C, Ruffie C, Haile S, Vargaftig BB, Pereira P, Pretolani M. Requirement for T cells in allergic airway inflammation. Science 1998;280:1265-7.
-
(1998)
Science
, vol.280
, pp. 1265-1267
-
-
Zuany-Amorim, C.1
Ruffie, C.2
Haile, S.3
Vargaftig, B.B.4
Pereira, P.5
Pretolani, M.6
-
56
-
-
0033120971
-
CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness
-
Schwarze J, Cieslewicz G, Joetham A, Ikemura T, Hamelmann E, Gelfand EW. CD8 T cells are essential in the development of respiratory syncytial virus-induced lung eosinophilia and airway hyperresponsiveness. J Immunol 1999;162:4207-11.
-
(1999)
J Immunol
, vol.162
, pp. 4207-4211
-
-
Schwarze, J.1
Cieslewicz, G.2
Joetham, A.3
Ikemura, T.4
Hamelmann, E.5
Gelfand, E.W.6
-
57
-
-
0030068998
-
Regulation of house dust mite responses by intranasally administered peptide: Transient activation of CD4+ T cells precedes the development of tolerance in vivo
-
Hoyne GF, Askonas BA, Hetzel C, Thomas WR, Lamb JR. Regulation of house dust mite responses by intranasally administered peptide: transient activation of CD4+ T cells precedes the development of tolerance in vivo. Int Immunol 1996;8:335-42.
-
(1996)
Int Immunol
, vol.8
, pp. 335-342
-
-
Hoyne, G.F.1
Askonas, B.A.2
Hetzel, C.3
Thomas, W.R.4
Lamb, J.R.5
-
58
-
-
0033763860
-
Immunological tolerance to inhaled antigen
-
Hoyne GF, Tan K, Corsin-Jimenez M, Wahl K, Stewart M, Howie SE, et al. Immunological tolerance to inhaled antigen. Am J Respir Crit Care Med 2000;162:S169-74.
-
(2000)
Am J Respir Crit Care Med
, vol.162
-
-
Hoyne, G.F.1
Tan, K.2
Corsin-Jimenez, M.3
Wahl, K.4
Stewart, M.5
Howie, S.E.6
-
59
-
-
0033845105
-
Mechanisms preventing allergen-induced airways hyperreactivity: Role of immune deviation and tolerance
-
Tsitoura DC, Blumenthal RL, Berry G, DeKruyff RH, Umetsu DT. Mechanisms preventing allergen-induced airways hyperreactivity: Role of immune deviation and tolerance. J Allergy Clin Immunol 2000;106:239-46.
-
(2000)
J Allergy Clin Immunol
, vol.106
, pp. 239-246
-
-
Tsitoura, D.C.1
Blumenthal, R.L.2
Berry, G.3
DeKruyff, R.H.4
Umetsu, D.T.5
-
60
-
-
0034890907
-
Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen
-
Akbari O, DeKruyff RH, Umetsu DT. Pulmonary dendritic cells secreting IL-10 mediate T cell tolerance induced by respiratory exposure to antigen. Nat Immunol 2001;2:725-31.
-
(2001)
Nat Immunol
, vol.2
, pp. 725-731
-
-
Akbari, O.1
DeKruyff, R.H.2
Umetsu, D.T.3
-
61
-
-
0035903326
-
Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo
-
Hawiger D, Inaba K, Dorsett Y, Guo M, Mahnke K, Rivera M, et al. Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo. J Exp Med 2001;194:769-79.
-
(2001)
J Exp Med
, vol.194
, pp. 769-779
-
-
Hawiger, D.1
Inaba, K.2
Dorsett, Y.3
Guo, M.4
Mahnke, K.5
Rivera, M.6
-
62
-
-
0035862333
-
Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells
-
Dhodapkar M, Steinman R, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med 2001;193:233-8.
-
(2001)
J Exp Med
, vol.193
, pp. 233-238
-
-
Dhodapkar, M.1
Steinman, R.2
Krasovsky, J.3
Munz, C.4
Bhardwaj, N.5
-
64
-
-
0035804268
-
ICOS is critical for CD40-mediated antibody class switching
-
McAdam AJ, Greenwald RJ, Levin MA, Chernova T, Malenkovich N, Ling V, et al. ICOS is critical for CD40-mediated antibody class switching. Nature 2001;409:102-5.
-
(2001)
Nature
, vol.409
, pp. 102-105
-
-
McAdam, A.J.1
Greenwald, R.J.2
Levin, M.A.3
Chernova, T.4
Malenkovich, N.5
Ling, V.6
-
65
-
-
0035804254
-
ICOS co-stimulatory receptor is essential for T-cell activation and function
-
Dong C, Juedes AE, Temann UA, Shresta S, Allison JP, Ruddle NH, et al. ICOS co-stimulatory receptor is essential for T-cell activation and function. Nature 2001;409:97-101.
-
(2001)
Nature
, vol.409
, pp. 97-101
-
-
Dong, C.1
Juedes, A.E.2
Temann, U.A.3
Shresta, S.4
Allison, J.P.5
Ruddle, N.H.6
-
67
-
-
0037340349
-
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
-
Grimbacher B, Hutloff A, Schlesier M, Glocker E, Warnatz K, Drager R, et al. Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency. Nat Immunol 2003;4:261-8.
-
(2003)
Nat Immunol
, vol.4
, pp. 261-268
-
-
Grimbacher, B.1
Hutloff, A.2
Schlesier, M.3
Glocker, E.4
Warnatz, K.5
Drager, R.6
-
68
-
-
0037911660
-
Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity
-
Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, et al. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nat Med 2003;9:582-8.
-
(2003)
Nat Med
, vol.9
, pp. 582-588
-
-
Akbari, O.1
Stock, P.2
Meyer, E.3
Kronenberg, M.4
Sidobre, S.5
Nakayama, T.6
-
69
-
-
0031028170
-
Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells
-
Smiley ST, Kaplan MH, Grusby MJ. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science 1997;275:977-9.
-
(1997)
Science
, vol.275
, pp. 977-979
-
-
Smiley, S.T.1
Kaplan, M.H.2
Grusby, M.J.3
-
70
-
-
0029959243
-
Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses
-
Brown D, Fowell D, Corry D, Wynn T, Moskowitz N, Cheever A, et al. Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses. J Exp Med 1996;184:1295-304.
-
(1996)
J Exp Med
, vol.184
, pp. 1295-1304
-
-
Brown, D.1
Fowell, D.2
Corry, D.3
Wynn, T.4
Moskowitz, N.5
Cheever, A.6
-
71
-
-
0034885046
-
The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells
-
Weiner HL. The mucosal milieu creates tolerogenic dendritic cells and Tr1 and Th3 regulatory cells. Nat Immunol 2001;2:671-2.
-
(2001)
Nat Immunol
, vol.2
, pp. 671-672
-
-
Weiner, H.L.1
-
72
-
-
0034327264
-
T regulatory cells 1 inhibit a Th2-specific response in vivo
-
Cottrez F, Hurst SD, Coffman RL, Groux H. T regulatory cells 1 inhibit a Th2-specific response in vivo. J Immunol 2000;165:4848-53.
-
(2000)
J Immunol
, vol.165
, pp. 4848-4853
-
-
Cottrez, F.1
Hurst, S.D.2
Coffman, R.L.3
Groux, H.4
-
73
-
-
0036732461
-
Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity
-
Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, et al. Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity. Nat Med 2002;8:1024-32.
-
(2002)
Nat Med
, vol.8
, pp. 1024-1032
-
-
Akbari, O.1
Freeman, G.J.2
Meyer, E.H.3
Greenfield, E.A.4
Chang, T.T.5
Sharpe, A.H.6
-
74
-
-
0035881129
-
Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways
-
Suto A, Nakajima H, Kagami S, Suzuki K, Saito Y, Iwamoto I. Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways. Am J Respir Crit Care Med 2001;164:680-7.
-
(2001)
Am J Respir Crit Care Med
, vol.164
, pp. 680-687
-
-
Suto, A.1
Nakajima, H.2
Kagami, S.3
Suzuki, K.4
Saito, Y.5
Iwamoto, I.6
-
75
-
-
0037514382
-
Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity
-
Hadeiba H, Locksley R. Lung CD25 CD4 regulatory T cells suppress type 2 immune responses but not bronchial hyperreactivity. J Immunol 2003;170:5502-10.
-
(2003)
J Immunol
, vol.170
, pp. 5502-5510
-
-
Hadeiba, H.1
Locksley, R.2
-
76
-
-
0019984839
-
Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction
-
Wannemuehler MJ, Kiyono H, Babb JL, Michalek SM, McGhee JR. Lipopolysaccharide (LPS) regulation of the immune response: LPS converts germfree mice to sensitivity to oral tolerance induction. J Immunol 1982;129:959-65.
-
(1982)
J Immunol
, vol.129
, pp. 959-965
-
-
Wannemuehler, M.J.1
Kiyono, H.2
Babb, J.L.3
Michalek, S.M.4
McGhee, J.R.5
-
77
-
-
0031571230
-
The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
-
Sudo N, Sawamura S, Tanaka K, Aiba Y, Kubo C, Koga Y. The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J Immunol 1997;159:1739-45.
-
(1997)
J Immunol
, vol.159
, pp. 1739-1745
-
-
Sudo, N.1
Sawamura, S.2
Tanaka, K.3
Aiba, Y.4
Kubo, C.5
Koga, Y.6
-
78
-
-
0035204919
-
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
-
McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2001;2:1109-16.
-
(2001)
Nat Immunol
, vol.2
, pp. 1109-1116
-
-
McIntire, J.J.1
Umetsu, S.E.2
Akbari, O.3
Potter, M.4
Kuchroo, V.K.5
Barsh, G.S.6
-
79
-
-
0034639769
-
Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: Epidemiological study
-
Matricardi P, Rosmini F, Riondino S, Fortini M, Ferrigno L, Rapicetta M, et al. Exposure to foodborne and orofecal microbes versus airborne viruses in relation to atopy and allergic asthma: epidemiological study. BMJ 2000;320:412-7.
-
(2000)
BMJ
, vol.320
, pp. 412-417
-
-
Matricardi, P.1
Rosmini, F.2
Riondino, S.3
Fortini, M.4
Ferrigno, L.5
Rapicetta, M.6
-
80
-
-
0036738382
-
Hay fever and asthma in relation to markers of infection in the United States
-
Matricardi PM, Rosmini F, Panetta V, Ferrigno L, Bonini S. Hay fever and asthma in relation to markers of infection in the United States. J Allergy Clin Immunol 2002;110:381-7.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 381-387
-
-
Matricardi, P.M.1
Rosmini, F.2
Panetta, V.3
Ferrigno, L.4
Bonini, S.5
-
81
-
-
0037136537
-
The effect of infections on susceptibility to autoimmune and allergic diseases
-
Bach J. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med 2002;347:911-20.
-
(2002)
N Engl J Med
, vol.347
, pp. 911-920
-
-
Bach, J.1
-
82
-
-
0031903498
-
The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor
-
Feigelstock D, Thompson P, Mattoo P, Zhang Y, Kaplan GG. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J Virol 1998;72:6621-8.
-
(1998)
J Virol
, vol.72
, pp. 6621-6628
-
-
Feigelstock, D.1
Thompson, P.2
Mattoo, P.3
Zhang, Y.4
Kaplan, G.G.5
-
83
-
-
0036347603
-
Asthma: An epidemic of dysregulated immunity
-
Umetsu D, McIntire J, Macaubas C, Akbari O, DeKruyff R. Asthma: an epidemic of dysregulated immunity. Nat Immunol 2002;3:715-20.
-
(2002)
Nat Immunol
, vol.3
, pp. 715-720
-
-
Umetsu, D.1
McIntire, J.2
Macaubas, C.3
Akbari, O.4
DeKruyff, R.5
|