Apoptosis defects and chemotherapy resistance: Molecular interaction maps and networks

Oncogene

Volumn 23, Issue 16 REV. ISS. 2, 2004, Pages 2934-2949

  Pommier, Yves ^a,c   Sordet, Olivier ^a   Antony, Smitha ^a   Hayward, Richard L ^b   Kohn, Kurt W ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

^c INSTITUT PASTEUR   (France)

Author keywords

Apoptosis; Camptothecins; Cancer chemotherapy; Multidrug resistance

Indexed keywords

17 ALLYLAMINOGELDANAMYCIN; 2 MORPHOLINO 8 PHENYLCHROMONE; 7 HYDROXYSTAUROSPORINE; ABELSON KINASE; ANTINEOPLASTIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; ARSENIC; CASPASE 2; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 9; CHECKPOINT KINASE 2; CYTOCHROME C; DNA TOPOISOMERASE INHIBITOR; G 3159; GELDANAMYCIN; HEAT SHOCK PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LONIDAMINE; OBLIMERSEN; PROTEIN BCL 2; PROTEIN DERIVATIVE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; PROTEIN P53; RADICICOL; STAUROSPORINE; TOPOTECAN; UNCLASSIFIED DRUG; UNINDEXED DRUG; AKT1 PROTEIN, HUMAN; APAF1 PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN; PROTEIN SERINE THREONINE KINASE;

APOPTOSIS; CANCER CHEMOTHERAPY; CELL DEATH; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CLINICAL TRIAL; CORRELATION ANALYSIS; DEREGULATION; DISEASE ASSOCIATION; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; GENE CLUSTER; GENE MAPPING; GENE OVEREXPRESSION; GENE TARGETING; GENETIC VARIABILITY; HUMAN; MITOCHONDRIAL RESPIRATION; MOLECULAR INTERACTION; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; REVIEW; SEQUENCE HOMOLOGY; ANIMAL; DRUG RESISTANCE; METABOLISM; NEOPLASM; PATHOLOGY; PHYSIOLOGY;

ANIMALS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; DRUG RESISTANCE, NEOPLASM; HUMANS; NEOPLASMS; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 2442464889     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207515     Document Type: Review

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