-
1
-
-
0027537461
-
An apoptosis inhibiting baculovirus gene with a zinc finger like motif
-
Crook N.E., Clem R.J., Miller L.K. An apoptosis inhibiting baculovirus gene with a zinc finger like motif. J. Virol. 67:1993;2168-2174.
-
(1993)
J. Virol.
, vol.67
, pp. 2168-2174
-
-
Crook, N.E.1
Clem, R.J.2
Miller, L.K.3
-
2
-
-
0029583176
-
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
-
Hay B.A., Wassarman D.A., Rubin G.M. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell. 83:1995;1253-1262.
-
(1995)
Cell
, vol.83
, pp. 1253-1262
-
-
Hay, B.A.1
Wassarman, D.A.2
Rubin, G.M.3
-
3
-
-
0029595282
-
The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins
-
Rothe M., Pan M.G., Henzel W.J., Ayres T.M., Goeddel D.V. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins. Cell. 83:1995;1243-1252.
-
(1995)
Cell
, vol.83
, pp. 1243-1252
-
-
Rothe, M.1
Pan, M.G.2
Henzel, W.J.3
Ayres, T.M.4
Goeddel, D.V.5
-
4
-
-
0029838964
-
ITA, a vertebrate homologue of IAP that is expressed in T lymphocytes
-
Digby M.R., Kimpton W.G., York J.J., Connick T.E., Lowenthal J.W. ITA, a vertebrate homologue of IAP that is expressed in T lymphocytes. DNA Cell Biol. 15:1996;981-988.
-
(1996)
DNA Cell Biol.
, vol.15
, pp. 981-988
-
-
Digby, M.R.1
Kimpton, W.G.2
York, J.J.3
Connick, T.E.4
Lowenthal, J.W.5
-
5
-
-
15844425961
-
A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors
-
Duckett C.S., Nava V.E., Gedrich R.W., Clem R.J., Vandongen J.L., Gilfillan M.C., Shiels H., Hardwick J.M., Thompson C.B. A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors. EMBO J. 15:1996;2685-2694.
-
(1996)
EMBO J.
, vol.15
, pp. 2685-2694
-
-
Duckett, C.S.1
Nava, V.E.2
Gedrich, R.W.3
Clem, R.J.4
Vandongen, J.L.5
Gilfillan, M.C.6
Shiels, H.7
Hardwick, J.M.8
Thompson, C.B.9
-
6
-
-
0029953942
-
Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
-
Uren A.G., Pakusch M., Hawkins C.J., Puls K.L., Vaux D.L. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors. Proc. Natl Acad. Sci. USA. 93:1996;4974-4978.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 4974-4978
-
-
Uren, A.G.1
Pakusch, M.2
Hawkins, C.J.3
Puls, K.L.4
Vaux, D.L.5
-
7
-
-
13344278692
-
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
-
Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Chertonhorvat G., Farahani R., Mclean M., Ikeda J.E., Mackenzie A., Korneluk R.G. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature. 379:1996;349-353.
-
(1996)
Nature
, vol.379
, pp. 349-353
-
-
Liston, P.1
Roy, N.2
Tamai, K.3
Lefebvre, C.4
Baird, S.5
Chertonhorvat, G.6
Farahani, R.7
McLean, M.8
Ikeda, J.E.9
Mackenzie, A.10
Korneluk, R.G.11
-
8
-
-
0032078249
-
Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRps) in viruses, nematodes, vertebrates and yeasts
-
Uren A.G., Coulson E.J., Vaux D.L. Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRps) in viruses, nematodes, vertebrates and yeasts. Trends Biochem. Sci. 23:1998;159-162.
-
(1998)
Trends Biochem. Sci.
, vol.23
, pp. 159-162
-
-
Uren, A.G.1
Coulson, E.J.2
Vaux, D.L.3
-
9
-
-
0034597630
-
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
-
Vucic D., Stennicke H.R., Pisabarro M.T., Salvesen G.S., Dixit V.M. ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas. Curr. Biol. 10:2000;1359-1366.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1359-1366
-
-
Vucic, D.1
Stennicke, H.R.2
Pisabarro, M.T.3
Salvesen, G.S.4
Dixit, V.M.5
-
10
-
-
0035793557
-
Livin, a novel inhibitor of apoptosis protein family member
-
Kasof G.M., Gomes B.C. Livin, a novel inhibitor of apoptosis protein family member. J. Biol. Chem. 276:2001;3238-3246.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3238-3246
-
-
Kasof, G.M.1
Gomes, B.C.2
-
11
-
-
0034993758
-
Two kinds of BIR-containing protein - Inhibitors of apoptosis, or required for mitosis
-
Silke J., Vaux D.L. Two kinds of BIR-containing protein - inhibitors of apoptosis, or required for mitosis. J. Cell Sci. 114:2001;1821-1827.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 1821-1827
-
-
Silke, J.1
Vaux, D.L.2
-
12
-
-
85003690856
-
Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila
-
Wright E.K., Goodart S.A., Growney J.D., Hadinoto V., Endrizzi M.G., Long E.M., Sadigh K., Abney A.L., Bernstein-Hanley I., Dietrich W.F. Naip5 affects host susceptibility to the intracellular pathogen Legionella pneumophila. Curr. Biol. 2002.
-
(2002)
Curr. Biol.
-
-
Wright, E.K.1
Goodart, S.A.2
Growney, J.D.3
Hadinoto, V.4
Endrizzi, M.G.5
Long, E.M.6
Sadigh, K.7
Abney, A.L.8
Bernstein-Hanley, I.9
Dietrich, W.F.10
-
13
-
-
0037228017
-
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
-
Diez E., Lee S.-H., Gauthier S., Yaraghi Z., Tremblay M., Vidal S., Gros P. Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila. Nat. Genet. 33:2002;55-60.
-
(2002)
Nat. Genet.
, vol.33
, pp. 55-60
-
-
Diez, E.1
Lee, S.-H.2
Gauthier, S.3
Yaraghi, Z.4
Tremblay, M.5
Vidal, S.6
Gros, P.7
-
14
-
-
0037046814
-
Drosophila BRUCE can potently suppress Rpr- and Grim-dependent but not HID-dependent cell death
-
Vernooy S.Y., Chow V., Su J., Verbrugghe K., Yang J., Cole S., Olson M.R., Hay B.A. Drosophila BRUCE can potently suppress Rpr- and Grim-dependent but not HID-dependent cell death. Curr. Biol. 12:2002;1164-1168.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1164-1168
-
-
Vernooy, S.Y.1
Chow, V.2
Su, J.3
Verbrugghe, K.4
Yang, J.5
Cole, S.6
Olson, M.R.7
Hay, B.A.8
-
15
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
Deveraux Q.L., Roy N., Stennicke H.R., Vanarsdale T., Zhou Q., Srinivasula S.M., Alnemri E.S., Salvesen G.S., Reed J.C. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17:1998;2215-2223.
-
(1998)
EMBO J.
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Vanarsdale, T.4
Zhou, Q.5
Srinivasula, S.M.6
Alnemri, E.S.7
Salvesen, G.S.8
Reed, J.C.9
-
16
-
-
0032478717
-
A single BIR domain of XIAP sufficient for inhibiting caspases
-
Takahashi R., Deveraux Q., Tamm I., Welsh K., Assamunt N., Salvesen G.S., Reed J.C. A single BIR domain of XIAP sufficient for inhibiting caspases. J. Biol. Chem. 273:1998;7787-7790.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 7787-7790
-
-
Takahashi, R.1
Deveraux, Q.2
Tamm, I.3
Welsh, K.4
Assamunt, N.5
Salvesen, G.S.6
Reed, J.C.7
-
17
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
Srinivasula S.M., Hegde R., Saleh A., Datta P., Shiozaki E., Chai J.J., Lee R.A., Robbins P.D., Fernandes-Alnemri T., Shi Y.G., Alnemri E.S. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature. 410:2001;112-116.
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.J.6
Lee, R.A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.G.10
Alnemri, E.S.11
-
18
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
Chai J.J., Shiozaki E., Srinivasula S.M., Wu Q., Dataa P., Alnemri E.S., Shi Y.G. Structural basis of caspase-7 inhibition by XIAP. Cell. 104:2001;769-780.
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.J.1
Shiozaki, E.2
Srinivasula, S.M.3
Wu, Q.4
Dataa, P.5
Alnemri, E.S.6
Shi, Y.G.7
-
19
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y.G. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell. 9:2002;459-470.
-
(2002)
Mol. Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.G.1
-
20
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
Riedl S.J., Renatus M., Schwarzenbacher R., Zhou Q., Sun C., Fesik S.W., Liddington R.C., Salvesen G.S. Structural basis for the inhibition of caspase-3 by XIAP. Cell. 104:2001;791-800.
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.W.6
Liddington, R.C.7
Salvesen, G.S.8
-
21
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
Roy N., Deveraux Q.L., Takahashi R., Salvesen G.S., Reed J.C. The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16:1997;6914-6925.
-
(1997)
EMBO J.
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
-
22
-
-
0033588273
-
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
-
Wang S.L., Hawkins C.J., Yoo S.J., Muller H.A.J., Hay B.A. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell. 98:1999;453-463.
-
(1999)
Cell
, vol.98
, pp. 453-463
-
-
Wang, S.L.1
Hawkins, C.J.2
Yoo, S.J.3
Muller, H.A.J.4
Hay, B.A.5
-
23
-
-
0034282666
-
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM
-
Hawkins C.J., Yoo S.J., Peterson E.P., Wang S.L., Vernooy S.Y., Hay B.A. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. J. Biol. Chem. 275:2000;27084-27093.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27084-27093
-
-
Hawkins, C.J.1
Yoo, S.J.2
Peterson, E.P.3
Wang, S.L.4
Vernooy, S.Y.5
Hay, B.A.6
-
24
-
-
0034651987
-
The Drosophila caspase DRONC is regulated by DIAP1
-
Meier P., Silke J., Leevers S.J., Evan G.I. The Drosophila caspase DRONC is regulated by DIAP1. EMBO J. 19:2000;598-611.
-
(2000)
EMBO J.
, vol.19
, pp. 598-611
-
-
Meier, P.1
Silke, J.2
Leevers, S.J.3
Evan, G.I.4
-
25
-
-
0028200532
-
Genetic control of programmed cell death in Drosophila
-
White K., Grether M.E., Abrams J.M., Young L., Farrell K., Steller H. Genetic control of programmed cell death in Drosophila. Science. 264:1994;677-683.
-
(1994)
Science
, vol.264
, pp. 677-683
-
-
White, K.1
Grether, M.E.2
Abrams, J.M.3
Young, L.4
Farrell, K.5
Steller, H.6
-
26
-
-
0029161958
-
The head involution defective gene of Drosophila melanogaster functions in programmed cell death
-
Grether M.E., Abrams J.M., Agapite J., White K., Steller H. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9:1995;1694-1708.
-
(1995)
Genes Dev.
, vol.9
, pp. 1694-1708
-
-
Grether, M.E.1
Abrams, J.M.2
Agapite, J.3
White, K.4
Steller, H.5
-
27
-
-
0029742260
-
Grim, a novel cell death gene in Drosophila
-
Chen P., Nordstrom W., Gish B., Abrams J.M. Grim, a novel cell death gene in Drosophila. Genes Dev. 10:1996;1773-1782.
-
(1996)
Genes Dev.
, vol.10
, pp. 1773-1782
-
-
Chen, P.1
Nordstrom, W.2
Gish, B.3
Abrams, J.M.4
-
28
-
-
0037154010
-
Sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein
-
Srinivasula S.M., Datta P., Kobayashi M., Wu J.W., Fujioka M., Hegde R., Zhang Z.J., Mukattash R., Fernandes-Alnemri T., Shi Y.G., Jaynes J.B., Alnemri E.S. Sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. Curr. Biol. 12:2002;125-130.
-
(2002)
Curr. Biol.
, vol.12
, pp. 125-130
-
-
Srinivasula, S.M.1
Datta, P.2
Kobayashi, M.3
Wu, J.W.4
Fujioka, M.5
Hegde, R.6
Zhang, Z.J.7
Mukattash, R.8
Fernandes-Alnemri, T.9
Shi, Y.G.10
Jaynes, J.B.11
Alnemri, E.S.12
-
29
-
-
0037154009
-
Drosophila sickle is a novel grim-reaper cell death activator
-
Wing J.P., Karres J.S., Ogdahl J.L., Zhou L., Schwartz L.M., Nambu J.R. Drosophila sickle is a novel grim-reaper cell death activator. Curr. Biol. 12:2002;131-135.
-
(2002)
Curr. Biol.
, vol.12
, pp. 131-135
-
-
Wing, J.P.1
Karres, J.S.2
Ogdahl, J.L.3
Zhou, L.4
Schwartz, L.M.5
Nambu, J.R.6
-
30
-
-
0037154014
-
The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, GRIM, and HID
-
Christich A., Kauppila S., Chen P., Sogame N., Ho S.I., Abrams J.M. The damage-responsive Drosophila gene sickle encodes a novel IAP binding protein similar to but distinct from reaper, GRIM, and HID. Curr. Biol. 12:2002;137-140.
-
(2002)
Curr. Biol.
, vol.12
, pp. 137-140
-
-
Christich, A.1
Kauppila, S.2
Chen, P.3
Sogame, N.4
Ho, S.I.5
Abrams, J.M.6
-
31
-
-
0036809813
-
IAP degradation: Decisive blow or altruistic sacrifice?
-
Ditzel M., Meier P. IAP degradation: decisive blow or altruistic sacrifice? Trends Cell Biol. 12:2002;449-452.
-
(2002)
Trends Cell Biol.
, vol.12
, pp. 449-452
-
-
Ditzel, M.1
Meier, P.2
-
32
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
Verhagen A.M., Ekert P.G., Pakusch M., Silke J., Connolly L.M., Reid G.E., Moritz R.L., Simpson R.J., Vaux D.L. Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell. 102:2000;43-53.
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.M.1
Ekert, P.G.2
Pakusch, M.3
Silke, J.4
Connolly, L.M.5
Reid, G.E.6
Moritz, R.L.7
Simpson, R.J.8
Vaux, D.L.9
-
33
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
Du C.Y., Fang M., Li Y.C., Li L., Wang X.D. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell. 102:2000;33-42.
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.Y.1
Fang, M.2
Li, Y.C.3
Li, L.4
Wang, X.D.5
-
34
-
-
18544386724
-
Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
Hegde R., Srinivasula S.M., Zhang Z.J., Wassell R., Mukattash R., Cilenti L., DuBois G., Lazebnik Y., Zervos A.S., Fernandes-Alnemri T., Alnemri E.S. Identification of Omi/HtrA-2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. J. Biol. Chem. 277:2002;432-438.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 432-438
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.J.3
Wassell, R.4
Mukattash, R.5
Cilenti, L.6
DuBois, G.7
Lazebnik, Y.8
Zervos, A.S.9
Fernandes-Alnemri, T.10
Alnemri, E.S.11
-
35
-
-
0037016686
-
HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
-
Verhagen A.M., Silke J., Ekert P.G., Pakusch M., Kaufmann H., Connolly L.M., Day C.L., Tikoo A., Burke R., Wrobel C., Moritz R.L., Simpson R.J., Vaux D.L. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins. J. Biol. Chem. 277:2002;445-454.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 445-454
-
-
Verhagen, A.M.1
Silke, J.2
Ekert, P.G.3
Pakusch, M.4
Kaufmann, H.5
Connolly, L.M.6
Day, C.L.7
Tikoo, A.8
Burke, R.9
Wrobel, C.10
Moritz, R.L.11
Simpson, R.J.12
Vaux, D.L.13
-
36
-
-
0034785591
-
A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
-
Suzuki Y., Imai Y., Nakayama H., Takahashi K., Takio K., Takahashi R. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol. Cell. 8:2001;613-621.
-
(2001)
Mol. Cell
, vol.8
, pp. 613-621
-
-
Suzuki, Y.1
Imai, Y.2
Nakayama, H.3
Takahashi, K.4
Takio, K.5
Takahashi, R.6
-
37
-
-
0037016707
-
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
-
Martins L.M., Iaccarino I., Tenev T., Gschmeissner S., Totty N.F., Lemoine N.R., Savopoulos J., Gray C.W., Creasy C.L., Dingwall C., Downward J. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif. J. Biol. Chem. 277:2002;439-444.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 439-444
-
-
Martins, L.M.1
Iaccarino, I.2
Tenev, T.3
Gschmeissner, S.4
Totty, N.F.5
Lemoine, N.R.6
Savopoulos, J.7
Gray, C.W.8
Creasy, C.L.9
Dingwall, C.10
Downward, J.11
-
38
-
-
18244386261
-
The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity
-
van Loo G., van Gurp M., Depuydt B., Srinivasula S.M., Rodriguez I., Alnemri E.S., Gevaert K., Vandekerckhove J., Declercq W., Vandenabeele P. The serine protease Omi/HtrA2 is released from mitochondria during apoptosis. Omi interacts with caspase-inhibitor XIAP and induces enhanced caspase activity. Cell Death Differ. 9:2002;20-26.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 20-26
-
-
Van Loo, G.1
Van Gurp, M.2
Depuydt, B.3
Srinivasula, S.M.4
Rodriguez, I.5
Alnemri, E.S.6
Gevaert, K.7
Vandekerckhove, J.8
Declercq, W.9
Vandenabeele, P.10
-
39
-
-
17744369252
-
Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and HID?
-
Silke J., Verhagen A.M., Ekert P.G., Vaux D.L. Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and HID? Cell Death Differ. 7:2000;1275.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1275
-
-
Silke, J.1
Verhagen, A.M.2
Ekert, P.G.3
Vaux, D.L.4
-
40
-
-
0036233590
-
Generation and characterization of Smac/DIABLO-deficient mice
-
Okada H., Suh W.K., Jin J., Woo M., Du C., Elia A., Duncan G.S., Wakeham A., Itie A., Lowe S.W., Wang X., Mak T.W. Generation and characterization of Smac/DIABLO-deficient mice. Mol. Cell. Biol. 22:2002;3509-3517.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3509-3517
-
-
Okada, H.1
Suh, W.K.2
Jin, J.3
Woo, M.4
Du, C.5
Elia, A.6
Duncan, G.S.7
Wakeham, A.8
Itie, A.9
Lowe, S.W.10
Wang, X.11
Mak, T.W.12
-
41
-
-
0034710649
-
Structural and biochemical basis of apoptotic activation by Smac/DIABLO
-
Chai J.J., Du C.Y., Wu J.W., Kyin S., Wang X.D., Shi Y.G. Structural and biochemical basis of apoptotic activation by Smac/DIABLO. Nature. 406:2000;855-862.
-
(2000)
Nature
, vol.406
, pp. 855-862
-
-
Chai, J.J.1
Du, C.Y.2
Wu, J.W.3
Kyin, S.4
Wang, X.D.5
Shi, Y.G.6
-
42
-
-
85047697950
-
Tissue distribution of Diablo/Smac revealed by monoclonal antibodies
-
Tikoo A., O'Reilly L., Day C.L., Verhagen A.M., Pakusch M., Vaux D.L. Tissue distribution of Diablo/Smac revealed by monoclonal antibodies. Cell Death Differ. 9:2002;710-716.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 710-716
-
-
Tikoo, A.1
O'Reilly, L.2
Day, C.L.3
Verhagen, A.M.4
Pakusch, M.5
Vaux, D.L.6
-
43
-
-
0034700491
-
Structural basis of IAP recognition by Smac/DIABLO
-
Wu G., Chai J.J., Suber T.L., Wu J.W., Du C.Y., Wang X.D., Shi Y.G. Structural basis of IAP recognition by Smac/DIABLO. Nature. 408:2000;1008-1012.
-
(2000)
Nature
, vol.408
, pp. 1008-1012
-
-
Wu, G.1
Chai, J.J.2
Suber, T.L.3
Wu, J.W.4
Du, C.Y.5
Wang, X.D.6
Shi, Y.G.7
-
44
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Liu Z.H., Sun C.H., Olejniczak E.T., Meadows R.P., Betz S.F., Oost T., Herrmann J., Wu J.C., Fesik S.W. Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain. Nature. 408:2000;1004-1008.
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.H.1
Sun, C.H.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
Herrmann, J.7
Wu, J.C.8
Fesik, S.W.9
-
45
-
-
0036544535
-
The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites
-
Silke J., Hawkins C.J., Ekert P.G., Chew J., Day C.L., Pakusch M., Verhagen A.M., Vaux D.L. The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites. J. Cell Biol. 157:2002;115-124.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 115-124
-
-
Silke, J.1
Hawkins, C.J.2
Ekert, P.G.3
Chew, J.4
Day, C.L.5
Pakusch, M.6
Verhagen, A.M.7
Vaux, D.L.8
-
46
-
-
0036163042
-
A conserved tetrapeptide motif: Potentiating apoptosis through IAP-binding
-
Shi Y. A conserved tetrapeptide motif: potentiating apoptosis through IAP-binding. Cell Death Differ. 9:2002;93-95.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 93-95
-
-
Shi, Y.1
-
47
-
-
0034721940
-
NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP
-
Sun C.H., Cai M.L., Meadows R.P., Xu N., Gunasekera A.H., Herrmann J., Wu J.C., Fesik S.W. NMR structure and mutagenesis of the third Bir domain of the inhibitor of apoptosis protein XIAP. J. Biol. Chem. 275:2000;33777-33781.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33777-33781
-
-
Sun, C.H.1
Cai, M.L.2
Meadows, R.P.3
Xu, N.4
Gunasekera, A.H.5
Herrmann, J.6
Wu, J.C.7
Fesik, S.W.8
-
48
-
-
0035809172
-
DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9
-
Ekert P.G., Silke J., Hawkins C.J., Verhagen A.M., Vaux D.L. DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9. J. Cell Biol. 152:2001;483-490.
-
(2001)
J. Cell Biol.
, vol.152
, pp. 483-490
-
-
Ekert, P.G.1
Silke, J.2
Hawkins, C.J.3
Verhagen, A.M.4
Vaux, D.L.5
-
49
-
-
0035876176
-
Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP
-
Silke J., Ekert P.G., Day C.L., Hawkins C.J., Baca M., Chew J., Pakusch M., Verhagen A.M., Vaux D.L. Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP. EMBO J. 20:2001;3114-3123.
-
(2001)
EMBO J.
, vol.20
, pp. 3114-3123
-
-
Silke, J.1
Ekert, P.G.2
Day, C.L.3
Hawkins, C.J.4
Baca, M.5
Chew, J.6
Pakusch, M.7
Verhagen, A.M.8
Vaux, D.L.9
-
50
-
-
0033592470
-
NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
-
Sun C., Cai M., Gunasekera A.H., Meadows R.P., Wang H., Chen J., Zhang H., Wu W., Xu N., Ng S.C., Fesik S.W. NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP. Nature. 401:1999;818-821.
-
(1999)
Nature
, vol.401
, pp. 818-821
-
-
Sun, C.1
Cai, M.2
Gunasekera, A.H.3
Meadows, R.P.4
Wang, H.5
Chen, J.6
Zhang, H.7
Wu, W.8
Xu, N.9
Ng, S.C.10
Fesik, S.W.11
-
51
-
-
0035831022
-
Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
-
Huang Y.H., Park Y.C., Rich R.L., Segal D., Myszka D.G., Wu H. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell. 104:2001;781-790.
-
(2001)
Cell
, vol.104
, pp. 781-790
-
-
Huang, Y.H.1
Park, Y.C.2
Rich, R.L.3
Segal, D.4
Myszka, D.G.5
Wu, H.6
-
52
-
-
0035037802
-
Characterization of XIAP-deficient mice
-
Harlin H., Reffey S.B., Duckett C.S., Lindsten T., Thompson C.B. Characterization of XIAP-deficient mice. Mol. Cell. Biol. 21:2001;3604-3608.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3604-3608
-
-
Harlin, H.1
Reffey, S.B.2
Duckett, C.S.3
Lindsten, T.4
Thompson, C.B.5
-
53
-
-
0034723201
-
Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia
-
Faccio L., Fusco C., Chen A., Martinotti S., Bonventre J.V., Zervos A.S. Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia. J. Biol. Chem. 275:2000;2581-2588.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2581-2588
-
-
Faccio, L.1
Fusco, C.2
Chen, A.3
Martinotti, S.4
Bonventre, J.V.5
Zervos, A.S.6
-
54
-
-
0033825336
-
Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response
-
Gray C.W., Ward R.V., Karran E., Turconi S., Rowles A., Viglienghi D., Southan C., Barton A., Fantom K.G., West A., Savopoulos J., Hassan N.J., Clinkenbeard H., Hanning C., Amegadzie B., Davis J.B., Dingwall C., Livi G.P., Creasy C.L. Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress response. Eur. J. Biochem. 267:2000;5699-5710.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5699-5710
-
-
Gray, C.W.1
Ward, R.V.2
Karran, E.3
Turconi, S.4
Rowles, A.5
Viglienghi, D.6
Southan, C.7
Barton, A.8
Fantom, K.G.9
West, A.10
Savopoulos, J.11
Hassan, N.J.12
Clinkenbeard, H.13
Hanning, C.14
Amegadzie, B.15
Davis, J.B.16
Dingwall, C.17
Livi, G.P.18
Creasy, C.L.19
-
55
-
-
0036752926
-
The HtrA family of proteases: Implications for protein composition and cell fate
-
Clausen T., Southan C., Ehrmann M. The HtrA family of proteases: implications for protein composition and cell fate. Mol. Cell. 10:2002;443-455.
-
(2002)
Mol. Cell
, vol.10
, pp. 443-455
-
-
Clausen, T.1
Southan, C.2
Ehrmann, M.3
-
56
-
-
0033617146
-
A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein
-
Spiess C., Beil A., Ehrmann M. A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein. Cell. 97:1999;339-347.
-
(1999)
Cell
, vol.97
, pp. 339-347
-
-
Spiess, C.1
Beil, A.2
Ehrmann, M.3
-
57
-
-
0036263973
-
Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi
-
Li W.Y., Srinivasula S.M., Chai J.J., Li P.W., Wu J.W., Zhang Z.J., Alnemri E.S., Shi Y.G. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Nat. Struct. Biol. 9:2002;436-441.
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 436-441
-
-
Li, W.Y.1
Srinivasula, S.M.2
Chai, J.J.3
Li, P.W.4
Wu, J.W.5
Zhang, Z.J.6
Alnemri, E.S.7
Shi, Y.G.8
-
58
-
-
0036284171
-
HtrA - A renaissance protein
-
Day C.L., Hinds M.G. HtrA - A renaissance protein. Structure. 10:2002;737-739.
-
(2002)
Structure
, vol.10
, pp. 737-739
-
-
Day, C.L.1
Hinds, M.G.2
-
59
-
-
0028149332
-
Apoptotic cell death induced by intracellular proteolysis
-
Williams M.S., Henkart P.A. Apoptotic cell death induced by intracellular proteolysis. J. Immunol. 153:1994;4247-4255.
-
(1994)
J. Immunol.
, vol.153
, pp. 4247-4255
-
-
Williams, M.S.1
Henkart, P.A.2
-
60
-
-
0030691118
-
Apoptosis, haemopoiesis and leukaemogenesis
-
Ekert P.G., Vaux D.L. Apoptosis, haemopoiesis and leukaemogenesis. Baillieres Clin. Haematol. 10:1997;561-576.
-
(1997)
Baillieres Clin. Haematol.
, vol.10
, pp. 561-576
-
-
Ekert, P.G.1
Vaux, D.L.2
-
61
-
-
0347895102
-
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ
-
Arnt C.R., Chiorean M.V., Heldebrant M.V., Gores G.J., Kaufmann S.H. Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ. J. Biol. Chem. 277:2002;44236-44243.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44236-44243
-
-
Arnt, C.R.1
Chiorean, M.V.2
Heldebrant, M.V.3
Gores, G.J.4
Kaufmann, S.H.5
-
62
-
-
0035476255
-
Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria
-
Zhang X.D., Zhang X.Y., Gray C.P., Nguyen T., Hersey P. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by Smac/DIABLO release from mitochondria. Cancer Res. 61:2001;7339-7348.
-
(2001)
Cancer Res.
, vol.61
, pp. 7339-7348
-
-
Zhang, X.D.1
Zhang, X.Y.2
Gray, C.P.3
Nguyen, T.4
Hersey, P.5
-
63
-
-
0033151510
-
The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18) (q21;q21) associated with mucosa-associated lymphoid tissue lymphomas
-
Dierlamm J., Baens M., Wlodarska I., Stefanova-Ouzounova M., Hernandez J.M., Hossfeld D.K., De Wolf-Peeters C., Hagemeijer A., Van den Berghe H., Marynen P. The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18) (q21;q21) associated with mucosa-associated lymphoid tissue lymphomas. Blood. 93:1999;3601-3609.
-
(1999)
Blood
, vol.93
, pp. 3601-3609
-
-
Dierlamm, J.1
Baens, M.2
Wlodarska, I.3
Stefanova-Ouzounova, M.4
Hernandez, J.M.5
Hossfeld, D.K.6
De Wolf-Peeters, C.7
Hagemeijer, A.8
Van den Berghe, H.9
Marynen, P.10
-
64
-
-
0033638182
-
Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
-
Uren A.G., O'Rourke K., Aravind L., Pisabarro M.T., Seshagiri S., Koonin E.V., Dixit V.M. Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma. Mol. Cell. 6:2000;961-967.
-
(2000)
Mol. Cell
, vol.6
, pp. 961-967
-
-
Uren, A.G.1
O'Rourke, K.2
Aravind, L.3
Pisabarro, M.T.4
Seshagiri, S.5
Koonin, E.V.6
Dixit, V.M.7
-
65
-
-
0035942178
-
Thymocyte-targeted overexpression of XIAP transgene disrupts T lymphoid apoptosis and maturation
-
Conte D., Liston P., Wong J.W., Wright K.E., Korneluk R.G. Thymocyte-targeted overexpression of XIAP transgene disrupts T lymphoid apoptosis and maturation. Proc. Natl. Acad. Sci. USA. 98:2001;5049-5054.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5049-5054
-
-
Conte, D.1
Liston, P.2
Wong, J.W.3
Wright, K.E.4
Korneluk, R.G.5
-
66
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
Fulda S., Wick W., Weller M., Debatin K.M. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo. Nat. Med. 8:2002;808-815.
-
(2002)
Nat. Med.
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
Debatin, K.M.4
|