Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation

Journal of Biological Chemistry

Volumn 278, Issue 25, 2003, Pages 22374-22378

  Troussard, Armelle A ^a   Mawji, Nasrin M ^a   Ong, Christopher ^a   Mui, Alice ^a   St Arnaud, René ^b   Dedhar, Shoukat ^a,c  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c JACK BELL RESEARCH CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL ENGINEERING; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; METABOLISM; RNA;

PHOSPHORYLATION;

PROTEINS;

CYCLIN D1; DOUBLE STRANDED RNA; GLYCOGEN SYNTHASE KINASE 3BETA; INTEGRIN; INTEGRIN LINKED KINASE; MUTANT PROTEIN; PHOSPHATIDYLINOSITIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DEPENDENT KINASE 1; PHOSPHOLIPID; PHOSPHOTRANSFERASE; PROTEIN KINASE B; REGULATOR PROTEIN; SERINE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL METABOLISM; CELL PROLIFERATION; CELL SURVIVAL; CONDITIONAL GENE KNOCKOUT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GENE DISRUPTION; GENE REPRESSION; HUMAN; HUMAN CELL; KNOCKOUT GENE; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; BASE SEQUENCE; BONE MARROW CELLS; CELL LINE; DNA PRIMERS; ENZYME ACTIVATION; GENE DELETION; HUMANS; POLYMERASE CHAIN REACTION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 0037666792     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M303083200     Document Type: Article

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