Bcl-xL Blocks Transforming Growth Factor-β1-induced Apoptosis by Inhibiting Cytochrome c Release and not by Directly Antagonizing Apaf-1-dependent Caspase Activation in Prostate Epithelial Cells

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26614-26621

  Chipuk, Jerry E ^a,b   Bhat, Manjunatha ^a,b   Hsing, Andrew Y ^c,d   Ma, Jianjie ^a,b   Danielpour, David ^a,b,e  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

^d NONE   (United States)

^e Ireland Cancer Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CHEMICAL ACTIVATION; ENZYME INHIBITION; GENETIC ENGINEERING; GROWTH KINETICS;

CYTOCHROMES; EPITHELIAL CELLS;

BIOCHEMISTRY;

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; MITOCHONDRIAL ENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL XL; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; APAF1 PROTEIN, HUMAN; APAF1 PROTEIN, RAT; BCL2L1 PROTEIN, HUMAN; PROTEIN; PROTEIN BCL 2; PROTEIN BCL X; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CLONE; ENZYME ACTIVATION; ENZYME ASSAY; ENZYME RELEASE; GENE OVEREXPRESSION; IMMUNOPRECIPITATION; MALE; NONHUMAN; NORTHERN BLOTTING; NRP 154 CELL LINE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE EPITHELIUM; RAT; WESTERN BLOTTING; CELL LINE; DRUG EFFECT; EPITHELIUM CELL; HUMAN; METABOLISM; PATHOLOGY; PROSTATE; SIGNAL TRANSDUCTION;

ANIMALIA;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BCL-X PROTEIN; CASPASES; CELL LINE; CYTOCHROME C GROUP; ENZYME ACTIVATION; EPITHELIAL CELLS; HUMANS; MALE; PROSTATE; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035854790     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100913200     Document Type: Article

References (89)

1. Sporn, M. B., and Roberts, A. B. (1991) CIBA Found. Symp. 157, 1-6
2. Roberts, A. B., and Sporn, M. B. (1993) Growth Factors 8, 1-9
3. Roberts, A. B. (1998) Miner. Electrolyte Metab. 24, 111-119
4. Massague, J., and Chen, Y. G. (2000) Genes Dev. 14, 627-644
5. Massague, J., Andres, J., Attisano, L., Cheifetz, S., Lopez-Casillas, F., Ohtsuki, M., and Wrana, J. L. (1992) Mol. Reprod. Dev. 32, 99-104
6. Wrana, J. L. (1998) Miner. Electrolyte Metab. 24, 120-130
7. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massague, J. (1994) Nature 370, 341-347
8. Wrana, J. L., and Attisano, L. (1996) Trends Genet. 12, 493-496
9. Wrana, J. L., and Attisano, L. (2000) Cytokine Growth Factor Rev. 11, 5-13
10. Wrana, J. L. (2000) Cell 100, 189-192
11. Adachi-Yamada, T., Nakamura, M., Irie, K., Tomoyasu, Y., Sano, Y., Mori, E., Goto, S., Ueno, N., Nishida, Y., and Matsumoto, K. (1999) Mol. Cell. Biol. 19, 2322-2329
12. Axmann, A., Seidel, D., Reimann, T., Hempel, U., and Wenzel, K. W. (1998) Biochem. Biophys. Res. Commun. 249, 456-460
13. Atfi, A., Djelloul, S., Chastre, E., Davis, R., and Gespach, C. (1997) J. Biol. Chem. 272, 1429-1432
14. Yamaguchi, K., Shirakabe, K., Shibuya, H., Irie, K., Oishi, I., Ueno, N., Taniguchi, T., Nishida, E., and Matsumoto, K. (1995) Science 270, 2008-2011
15. Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., and Matsumoto, K. (1996) Science 272, 1179-1182
16. ten Dijke, P., Miyazono, K., and Heldin, C. H. (2000) Trends Biochem. Sci. 25, 64-70
17. White, E. (1996) Genes Dev. 10, 1-15
18. Jacobson, M. D., Weil, M., and Raff, M. C. (1997) Cell 88, 347-354
19. Milligan, C. E., and Schwartz, L. M. (1997) Br. Med. Bull. 53, 570-590
20. Ellis, H. M., and Horvitz, H. R. (1986) Cell 44, 817-829
21. Hedgecock, E. M., Sulston, J. E., and Thomson, J. N. (1983) Science 220, 1277-1279
22. Chao, D. T., and Korsmeyer, S. J. (1997) Int. Immunol. 9, 1375-1384
23. Krajewski, S., Krajewska, M., Shabaik, A., Wang, H. G., Irie, S., Fong, L., and Reed, J. C. (1994) Cancer Res. 54, 5501-5507
24. Nunez, G., Merino, R., Simonian, P. L., and Grillot, D. A. (1996) Adv. Exp. Med. Biol. 406, 75-82
25. Gonzalez-Garcia, M., Perez-Ballestero, R., Ding, L., Duan, L., Boise, L. H., Thompson, C. B., and Nunez, G. (1994) Development 120, 3033-3042
26. Muchmore, S. W., Sattler, M., Liang, H., Meadows, R. P., Harlan, J. E., Yoon, H. S., Nettesheim, D., Chang, B. S., Thompson, C. B., Wong, S. L., Ng, S. L., and Fesik, S. W. (1996) Nature 381, 335-341
27. Vander Heiden, M. G., Chandel, N. S., Williamson, E. K., Schumacker, P. T., and Thompson, C. B. (1997) Cell 91, 627-637
28. Vander Heiden, M. G., Chandel, N. S., Schumacker, P. T., and Thompson, C. B. (1999) Mol. Cell 3, 159-167
29. Cai, J., Yang, J., and Jones, D. P. (1998) Biochim. Biophys. Acta 1366, 139-149
30. Shimizu, S., Shinohara, Y., and Tsujimoto, Y. (2000) Oncogene 19, 4309-4318
31. Finucane, D. M., Bossy-Wetzel, E., Waterhouse, N. J., Cotter, T. G., and Green, D. R. (1999) J. Biol. Chem. 274, 2225-2233
32. Manon, S., Chaudhuri, B., and Guerin, M. (1997) FEBS Lett. 415, 29-32
33. Holinger, E. P., Chittenden, T., and Lutz, R. J. (1999) J. Biol. Chem. 274, 13298-13304
34. Sattler, M., Liang, H., Nettesheim, D., Meadows, R. P., Harlan, J. E., Eberstadt, M., Yoon, H. S., Shuker, S. B., Chang, B. S., Minn, A. J., Thompson, C. B., and Fesik, S. W. (1997) Science 275, 983-986
35. Yang, E., Zha, J., Jockel, J., Boise, L. H., Thompson, C. B., and Korsmeyer, S. J. (1995) Cell 80, 285-291
36. Hu, Y., Benedict, M. A., Wu, D., Inohara, N., and Nunez, G. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4386-4391
37. Kyprianou, N., and Isaacs, J. T. (1989) Mol. Endocrinol. 3, 1515-1522
38. Kim, I. Y., Ahn, H. J., Zelner, D. J., Park, L., Sensibar, J. A., and Lee, C. (1996) Mol. Endocrinol. 10, 107-115
39. Brodin, G., ten Dijke, P., Funa, K., Heldin, C. H., and Landstrom, M. (1999) Cancer Res. 59, 2731-2738
40. Guo, Y., and Kyprianou, N. (1999) Cancer Res. 59, 1366-1371
41. Hsing, A. Y., Kadomatsu, K., Bonham, M. J., and Danielpour, D. (1996) Cancer Res. 56, 5146-5149
42. Danielpour, D., Kadomatsu, K., Anzano, M. A., Smith, J. M., and Sporn, M. B. (1994) Cancer Res. 54, 3413-3421
43. Larisch-Bloch, S., Danielpour, D., Roche, N. S., Lotan, R., Hsing, A. Y., Kerner, H., Hajouj, T., Lechleider, R. J., and Roberts, A. B. (2000) Cell Growth Differ. 11, 1-10
44. Krajewska, M., Krajewski, S., Epstein, J. I., Shabaik, A., Sauvageot, J., Song, K., Kitada, S., and Reed, J. C. (1996) Am. J. Pathol. 148, 1567-1576
45. Bossy-Wetzel, E., and Green, D. R. (2000) Methods Enzymol. 322, 235-242
46. Wu, D., Wallen, H. D., and Nunez, G. (1997) Science 275, 1126-1129
47. Han, Z., Hendrickson, E. A., Bremner, T. A., and Wyche, J. H. (1997) J. Biol. Chem. 272, 13432-13436
48. Lam, M., Bhat, M. B., Nunez, G., Ma, J., and Distelhorst, C. W. (1998) J. Biol. Chem. 273, 17307-17310
49. Danielpour, D. (1999) J. Cell Sci. 112, 169-179
50. Tu, H., Jacobs, S. C., Borkowski, A., and Kyprianou, N. (1996) Int. J. Cancer 69, 357-363
51. Tang, D. G., Li, L., Chopra, D. P., and Porter, A. T. (1998) Cancer Res. 58, 3466-3479
52. Varga, J., Rosenbloom, J., and Jimenez, S. A. (1987) Biochem. J. 247, 597-604
53. Hocevar, B. A., Brown, T. L., and Howe, P. H. (1999) EMBO J. 18, 1345-1356
54. Kim, T. A., Ravitz, M. J., and Wenner, C. E. (1994) J. Cell. Physiol. 160, 1-9
55. Muller, H., and Helin, K. (2000) Biochim. Biophys. Acta 1470, M1-M12
56. Li, J. M., Hu, P. P., Shen, X., Yu, Y., and Wang, X. F. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 4948-4953
57. Lukas, J., Herzinger, T., Hansen, K., Moroni, M. C., Resnitzky, D., Helin, K., Reed, S. I., and Bartek, J. (1997) Genes Dev. 11, 1479-1492
58. Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S., and Dixit, V. M. (1995) Cell 81, 801-809
59. Pan, G., O'Rourke, K., and Dixit, V. M. (1998) J. Biol. Chem. 273, 5841-5845
60. Newmeyer, D. D., Bossy-Wetzel, E., Kluck, R. M., Wolf, B. B., Beere, H. M., and Green, D. R. (2000) Cell Death Differ. 7, 402-407
61. Freathy, C., Brown, D. G., Roberts, R. A., and Cain, K. (2000) Hepatology 32, 750-760
62. Fabregat, I., Herrera, B., Fernandez, M., Alvarez, A. M., Sanchez, A., Roncero, C., Ventura, J. J., Valverde, A. M., and Benito, M. (2000) Hepatology 32, 528-535
63. Horoszewicz, J. S., Leong, S. S., Chu, T. M., Wajsman, Z. L., Friedman, M., Papsidero, L., Kim, U., Chai, L. S., Kakati, S., Arya, S. K., and Sandberg, A. A. (1980) Prog. Clin. Biol. Res. 37, 115-132
64. Mickey, D. D., Stone, K. R., Wunderli, H., Mickey, G. H., Vollmer, R. T., and Paulson, D. F. (1977) Cancer Res. 37, 4049-4058
65. Kokontis, J., Ito, K., Hiipakka, R. A., and Liao, S. (1991) Receptor 1, 271-279
66. Schuurmans, A. L., Bolt, J., Veldscholte, J., and Mulder, E. (1991) J. Steroid Biochem. Mol. Biol. 40, 193-197
67. Hartley-Asp, B., and Gunnarsson, P. O. (1982) J. Urol. 127, 818-822
68. Pollard, M. (1998) Prostate 37, 1-4
69. Brown, T. L., Patil, S., Cianci, C. D., Morrow, J. S., and Howe, P. H. (1999) J. Biol. Chem. 274, 23256-23262
70. Ohta, S., Yanagihara, K., and Nagata, K. (1997) Biochem. J. 324, 777-782
71. Hung, W. C., Chang, H. C., and Chuang, L. Y. (1998) Cell. Signal. 10, 511-515
72. Buchmann, A., Willy, C., Buenemann, C. L., Stroh, C., Schmiechen, A., and Schwarz, M. (1999) Cell Death Differ. 6, 190-200
73. Shima, Y., Nakao, K., Nakashima, T., Kawakami, A., Nakata, K., Hamasaki, K., Kato, Y., Eguchi, K., and Ishii, N. (1999) Hepatology 30, 1215-1222
74. Saltzman, A., Munro, R., Searfoss, G., Franks, C., Jaye, M., and Ivashchenko, Y. (1998) Exp. Cell Res. 242, 244-254
75. Burri, S. H., Kim, C. N., Fang, G., Chang, B. S., Perkins, C., Harris, W., Davis, L. W., Thompson, C. B., and Bhalla, K. N. (1999) Int. J. Radiat. Oncol. Biol. Phys. 43, 423-430
76. Gross, A., Yin, X. M., Wang, K., Wei, M. C., Jockel, J., Milliman, C., Erdjument-Bromage, H., Tempst, P., and Korsmeyer, S. J. (1999) J. Biol. Chem. 274, 1156-1163
77. Johnson, B. W., Cepero, E., and Boise, L. H. (2000) J. Biol. Chem. 275, 31546-31553
78. Carthy, C. M., Granville, D. J., Jiang, H., Levy, J. G., Rudin, C. M., Thompson, C. B., McManus, B. M., and Hunt, D. W. (1999) Lab. Invest. 79, 953-965
79. Gao, C., Zou, Z., Xu, L., Moul, J., Seth, P., and Srivastava, S. (2000) Int. J. Cancer 88, 191-194
80. Marcelli, M., Marani, M., Li, X., Sturgis, L., Haidacher, S. J., Trial, J. A., Mannucci, R., Nicoletti, I., and Denner, L. (2000) Prostate 42, 260-273
81. Takahashi, N., Shimizu, T., and Takeda, K. (2000) Prostate 44, 328-333
82. Zhang, H., Hoang, T., Saeed, B., and Ng, S. C. (1996) Prostate 29, 69-76
83. Chinnaiyan, A. M., O'Rourke, K., Lane, B. R., and Dixit, V. M. (1997) Science 275, 1122-1126
84. Chau, B. N., Cheng, E. H., Kerr, D. A., and Hardwick, J. M. (2000) Mol. Cell 6, 31-40
85. Li, F., Srinivasan, A., Wang, Y., Armstrong, R. C., Tomaselli, K. J., and Fritz, L. C. (1997) J. Biol. Chem. 272, 30299-30305
86. Hsu, Y. T., Wolter, K. G., and Youle, R. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3668-3672
87. Liu, Q. Y., and Stein, C. A. (1997) Clin. Cancer Res. 3, 2039-2046
88. Tang, B., de Castro, K., Barnes, H. E., Parks, W. T., Stewart, L., Böttinger, E. P., Danielpour, D., and Wakefield, L. M. (1999) Cancer Res. 59, 4834-4842
89. Larisch, S., Yi, Y., Lotan, R., Kerner, H., Eimerl, S., Parks, W. T., Gottfried, Y., Reffey Birkey, S., de Caestecker, M. P., Danielpour, D., Book-Melamed, N., Timberg, R., Duckett, C. S., Lechleider, R. J., Steller, H., Orly, J., Kim, S.-J., and Roberts, A. B. (2000) Nat. Cell Biol. 2, 915-921