The tumour suppressor CYLD negatively regulates NF-κB signalling by deubiquitination

Nature

Volumn 424, Issue 6950, 2003, Pages 801-805

  Kovalenko, Andrew ^a,b   Chable Bessia, Christine ^b   Cantarella, Giuseppina ^a,c   Israël, Alain ^b   Wallach, David ^a   Courtois, Gilles ^b  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b INSTITUT PASTEUR   (France)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; GENES; TUMORS;

PATHPHYSIOLOGY;

GENETIC ENGINEERING;

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NERVE GROWTH FACTOR RECEPTOR; POLYUBIQUITIN; UBIQUITIN; CHUK PROTEIN, HUMAN; CYLD PROTEIN, HUMAN; IKBKB PROTEIN, HUMAN; IKBKE PROTEIN, HUMAN; PROTEIN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; TUMOR SUPPRESSOR PROTEIN;

CANCER; MEDICINE;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL PROTECTION; CONTROLLED STUDY; CYLD GENE; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE; AMINO ACID SEQUENCE; CATALYSIS; CELL LINE; CHEMISTRY; DRUG ANTAGONISM; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN BINDING; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; CATALYSIS; CELL LINE; HUMANS; I-KAPPA B KINASE; MOLECULAR SEQUENCE DATA; MUTATION; NF-KAPPA B; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SUBSTRATE SPECIFICITY; TNF RECEPTOR-ASSOCIATED FACTOR 2; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

EID: 0041967054     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature01802     Document Type: Article

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