Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine

Neuroscience

Volumn 110, Issue 4, 2002, Pages 627-639

  Mesulam, M M ^a   Guillozet, A ^a   Shaw, P ^a   Levey, A ^b   Duysen, E G ^c   Lockridge, O ^c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Basal forebrain; Cerebral cortex; Choline acetyltransferase; Striatum

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ACETYLTHIOCHOLINE; CHOLINE; CHOLINESTERASE; NEUROTRANSMITTER;

ALZHEIMER DISEASE; ANATOMY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN; CHOLINERGIC SYSTEM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; FEMALE; GLIA; HYDROLYSIS; MALE; MOUSE; NERVE CELL; NONHUMAN; PARASYMPATHETIC INNERVATION; PRIORITY JOURNAL; SYNAPSE; TREATMENT PLANNING; WILD TYPE;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; BRAIN; BUTYRYLCHOLINESTERASE; CHOLINE O-ACETYLTRANSFERASE; CHOLINERGIC FIBERS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HYDROLYSIS; MALE; MICE; MICE, KNOCKOUT; NADPH DEHYDROGENASE; NEURAL PATHWAYS; NEUROGLIA; NEURONS; PRESYNAPTIC TERMINALS; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC;

EID: 0037012468     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(01)00613-3     Document Type: Article

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