The Alzheimer's disease amyloid precursor protein modulates copper- induced toxicity and oxidative stress in primary neuronal cultures

Journal of Neuroscience

Volumn 19, Issue 21, 1999, Pages 9170-9179

  White, Anthony R ^a,b   Multhaup, Gerd ^c   Maher, Fran ^a,b   Bellingham, Shayne ^a   Camakaris, James ^a   Zheng, Hui ^d   Bush, Ashley I ^a,b,e   Beyreuther, Konrad ^c   Masters, Colin L ^a,b   Cappai, Roberto ^a,b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d MERCK RESEARCH LABORATORIES   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alzheimer's; Copper; Culture; Free radicals; Knockout; Lipid peroxidation; Neurons

Indexed keywords

AMYLOID PRECURSOR PROTEIN; COPPER; FREE RADICAL;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BINDING SITE; CELL DEATH; CELL FREE SYSTEM; CELL LOSS; DRUG INDUCED DISEASE; LIPID PEROXIDATION; MOUSE; MULTIGENE FAMILY; NERVE CELL CULTURE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; RECEPTOR DENSITY;

EID: 0033232709     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-21-09170.1999     Document Type: Article

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