Angiotensin-converting Enzyme Degrades Alzheimer Amyloid β-Peptide (Aβ); Retards Aβ Aggregation, Deposition, Fibril Formation; and Inhibits Cytotoxicity

Journal of Biological Chemistry

Volumn 276, Issue 51, 2001, Pages 47863-47868

  Hu, Jianguo ^a   Igarashi, Akira ^a   Kamata, Makiko ^a   Nakagawa, Hachiro ^a  

^a BioMedical Laboratories Inc   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; AMINO ACIDS; BRAIN; DEPOSITION; DISEASES; ELECTRON MICROSCOPY; GENES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TISSUE;

FIBRIL FORMATION;

ENZYMES;

AMYLOID BETA PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LISINOPRIL; AMYLOID BETA PROTEIN (1 40); AMYLOID BETA-PROTEIN (1-40); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; AUTOPSY; BRAIN TISSUE; CELL STRAIN; CONTROLLED STUDY; CYTOTOXICITY; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME DEGRADATION; FIBER; GENETIC SUSCEPTIBILITY; GENOTYPE; IN VITRO STUDY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ANIMAL; ELECTRON MICROSCOPY; GENETICS; HUMAN; HYDROLYSIS; MASS SPECTROMETRY; METABOLISM;

ANIMALIA;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMAL; GENOTYPE; HUMAN; HYDROLYSIS; MICROSCOPY, ELECTRON; PC12 CELLS; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; RATS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0035930538     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104068200     Document Type: Article

References (45)

1. Hu, J., Miyatake, F., Aizu, Y., Nakagawa, H., Nakamura, S., Tamaoka, A., Takahashi, R., Urakami, K., and Shoji, M. (1999) Neurosci. Lett. 277, 65-67
2. Selkoe, D. J. (1994) Annu. Rev. Neurosci. 17, 489-517
3. Reid, I. A. (1992) Am. J. Physiol. 262, E763-E778
4. Rigat, B., Hubert, C., Alhenc-Gelas, F., Cambien, F., Corvol, P., and Soubrier, F. (1990) J. Clin. Invest. 86, 1343-1346
5. Abbud, Z. A., Wilson, A. C., Cosgrove, N. M., and Kosis, J. B. (1998) Am. J. Cardiol. 81, 244-246
6. Ledru, F., Blanchard, D., Battaglis, S., Jeunemaitre, X., Courbon, D., Guize, L., Guermonprez, J. L., Ducimetiere, P., and Diebold, B. (1998) Am. J. Cardiol. 82, 160-165
7. Vleming, L. J., van der Pijl, J. W., Lemkes, H. H., Westendorp R. G., Maassen J. A., Daha, M. R., van Es, L. A., and van Kooten, C. (1999) Clin. Nephrol. 51, 133-140
8. Kehoe, P. G., Russ, C., McIlroy, S., Williams, H., Holmans, P., Holmes, C., Liolitsa, D., Vahidassr, D., Powell, J., McGleenon, B., Liddell, M., Plomin, R., Dynan, K., Williams, N., Neal, J., Cairns, N. J., Wilcock, G., Passmore, P., Lovestone, S., Williams, J., and Owen, M. J. (1999) Nat. Genet. 21, 71-72
9. Alvarez, R., Alvarez, V., Lahoz, C. H., Martinez, C., Pena. J., Sanchez, J. M., Guisasola, L. M., Salas, Puig, J., Moris, G., Vidal, J. A., Ribacoba, R., Menes, B. B., Uria, D., and Coto, E. (1999) J. Neurol. Neurosurg. Psychiatry. 67, 733-736
10. Crawford, F., Abdullah, L., Schinka, J., Suo, Z., Gold, M., Duara, R., and Mullan, M. (2000) Neurosci. Lett. 280, 215-219
11. Farrer, L. A., Sherbatich, T., Keryanov, S. A., Korovaitseva, G. I., Rogaeva, E. A., Petruk, S., Premkumar, S., Moliaka, Y., Song, Y. Q., Pei, Y., Sato, C., Selezneva, N. D., Voskresenskaya, S., Golimbet, V., Sorbi, S., Duara, R., Gavrilova, S., St. George-Hyslop, P. H., and Rogaev, E. I. (2000) Arch. Neurol. 57, 210-214
12. Kamata, M., Hu, J., Shibahara, H., and Nakagawa, H. (2001) Int. J. Androl. 24, 225-231
13. Kasahara, Y., and Ashihara, Y. (1981) Clin. Chem. 27, 1922-1925
14. Lieberman, L. (1975) Am. J. Med. 59, 365-372
15. Hilbich, C., Kisters-Woike, B., Reed, J., Masters, C. L., and Beyreuther, K. (1991) J. Mol. Biol. 218, 149-163
16. Terzi, E., Holzemann, G., and Seelig, J. (1995) J. Mol. Biol. 252, 633-642
17. Levine, H. (1993) Protein Sci. 2, 404-410
18. Esler, W. P., Stimson, E. R., Ghilardi, J. R., Felix, A. M., Lu, Y-A., Vinters, H. V., Mantyh, P. W., and Maggio, J. E. (1997) Nat. Biotechnol. 15, 258-263
19. Shearman, M. S., Ragn, C. I., and Iversen, L. L. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 1470-1474
20. Ishiyama, M., Tominaga, H., Shiga, M., Sasamoto, K., Ohkura, Y., Ueno, K., and Watanabe, M. (1995) In Vitro Toxicol. 8, 187-190
21. Ishiyama, M., Miyazono, Y., Sasamoto, K., Ohkura, Y., and Ueno, K. (1997) Talanta 44, 1299-1305
22. Schachter, F., Faure-Delanef, L., Guenot, F., Rouger, H., Froguel, P., Lesueur-Ginot, L., and Cohen, D. (1994) Nat. Genet. 6, 29-32
23. Kakinuma, Y., Hama, H., Sugiyama, F., Yagami, K., Goto, K., Murakami, K., and Fukamizu, A. (1998) Nat. Med. 4, 1078-1080
24. Skoog, I., Wallin, A., and Fredman, P. (1998) Neurology 50, 966-971
25. Kakinuma, Y., Hama, H., Sugiyama, F., Goto, K., Murakami, K., and Fukamizu, A. (1997) Neurosci. Lett. 232, 167-170
26. Albrecht, D., Broser, M., and Kruger, H. (1997) Regul. Pept. 70, 105-109
27. Kramar, E. A., Harding, J. W., and Wright, J. W. (1997) Regul. Pept. 68, 131-138
28. Zhuo, J., Moeller, I., Jenkins, T., Chai, S. Y., Allen, A. M., Ohishi, M., and Mendelsohn, F. A. (1998) J. Hypertens. 16, 2027. 2037
29. Reardon, K. A., Mendelsohn, F. A., Chai, S. Y., and Horne, M. K. (2000) Aust. N Z. J. Med. 30, 48-53
30. Wright, J. W., Stubley, L., Pederson, E. S., Kramar, E. A., Hanesworth, J. M., and Harding, J. W. (1999) J. Neurosci. 19, 3952-3961
31. Pederson, E. S., Harding, J. W., and Wright J. W. (1998) Regul. Pept. 74, 97-103
32. Selkoe, D. J., Yamazaki, T., Citron, M., Podlisny, M. B., Koo, E. H., Teplow, D. B., and Haass, C. (1996) Ann. New York Acad: Sci. 777, 57-64
33. Lorenzo, A., and Yankner, B. A. (1996) Ann. New York Acad. Sci. 777, 89-95
34. Yanker, B. A. (1992) Neurobiol. Aging 13, 615-616
35. Pike, C. J., Burdick, D., Walencewicz, A. J., Glabe, C. G., and Cotman, C. W. (1993) J. Neurosci. 13, 1676-1687
36. Pike, C. J., Walencewicz, A. J., Glabe, C. G., and Cotman, C. W. (1991) Brain Res. 563, 311-314
37. Lorenzo, A., and Yankner, B. A. (1994) Proc. Natl. Acad. Sci U. S. A. 91, 12243-12247
38. Esler, W. P., Stimson, E. R., Ghilardi, J. P., Vinters, I. V., Lee, J. P., Mantyh, P. W., and Maggio, J. E. (1996) Biochemistry 35, 749-757
39. Mills, J., and Reiner, P. B. (1999) J. Neurochem. 72, 443-460
40. Nunan, J., and Small, D. H. (2000) FEBS Lett. 483, 6-10
41. Small, D. H. (1998) Neurochem. Res. 23, 795-806
42. Mok, S. S., Clippingdale, A. B., Beyreuther, K., Masters, C. L., Barrow, C. J., and Small, D. H. (2000) J. Neurosci. Res. 61, 449-457
43. Chesneau, V., Vekrellis, K., Rosner, M. R., and Selkoe, D. J. (2000) Biochem. J. 351, 509-516
44. Iwata, N., Tsubuki, S., Takaki, Y., Watanabe, K., Sekiguchi, M., Hosoki, E., Kawashima Morishima, M., Lee, H. J., Hama, E., Aizawa, S., Y., and Saido, T. C. (2000) Nat. Med. 6, 143-150
45. Yu, G. S. P., Hu, J., and Nakagawa, H. (1998) Neurosci. Lett. 254, 125-128