Nucleocytoplasmic transport: Cargo trafficking across the border

Current Opinion in Cell Biology

Volumn 14, Issue 3, 2002, Pages 328-335

  Weis, Karsten ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALRETICULIN; CELL NUCLEUS RECEPTOR; EXPORTIN; GLYCINE; KARYOPHERIN; MEMBRANE PROTEIN; NUCLEAR TRANSPORT FACTOR 2; PHENYLALANINE; PROTEIN MEX67; PROTEIN TAP; UNCLASSIFIED DRUG; MESSENGER RNA;

CELL NUCLEUS MEMBRANE; NONHUMAN; NUCLEAR PORE; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REVIEW; RNA PROCESSING; RNA SPLICING; RNA TRANSPORT; STRUCTURE ANALYSIS; ACTIVE TRANSPORT; ALTERNATIVE RNA SPLICING; ANIMAL; BIOLOGICAL MODEL; CELL NUCLEUS; CYTOPLASM; METABOLISM; PHYSIOLOGY; PROTEIN TRANSPORT; RIBOSOME; SIGNAL TRANSDUCTION;

ACTIVE TRANSPORT, CELL NUCLEUS; ALTERNATIVE SPLICING; ANIMALS; CALRETICULIN; CELL NUCLEUS; CYTOPLASM; KARYOPHERINS; MODELS, BIOLOGICAL; PROTEIN TRANSPORT; RIBOSOMES; RNA TRANSPORT; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0036591883     PISSN: 09550674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0955-0674(02)00337-X     Document Type: Review

References (73)

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4. Transport into and out of the nucleus
5. Importin-beta-like nuclear transport receptors
6. Running on Ran: Nuclear transport and the mitotic spindle
7. RanBP3 influences interactions between Crm1 and its nuclear protein export substrates
8. Ran-binding protein 3 is a cofactor for Crm1-mediated nuclear protein export
9. The mammalian Mog1 protein is a guanine nucleotide release factor for Ran
10. Interaction between Ran and Mog1 is required for efficient nuclear protein import
11. XMog1, a nuclear Ran-binding protein in Xenopus, is a functional homologue of Schizosaccharomyces pombe Mog1p that co-operates with RanBP1 to control generation of Ran-GTP
12. Multiple pathways contribute to nuclear import of core histones
13. Nuclear import of histone H2A and H2B is mediated by a network of karyopherins
14. Pathways mediating the nuclear import of histones H3 and H4 in yeast
15. The karyopherin Kap142p/Msn5p mediates nuclear import and nuclear export of different cargo proteins
16. Importin 13: A novel mediator of nuclear import and export
17. Calreticulin is a receptor for nuclear export
18. Nuclear export of the small ribosomal subunit requires the Ran-GTPase cycle and certain nucleoporins
19. Ultrastructural localization of rRNA shows defective nuclear export of preribosomes in mutants of the Nup82p complex
20. Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p
21. A nuclear AAA-type ATPase (Rix7p) is required for biogenesis and nuclear export of 60S ribosomal subunits
22. Maturation and intranuclear transport of pre-ribosomes requires Noc proteins
23. Factors affecting nuclear export of the 60S ribosomal subunit in vivo
24. Nmd3p is a Crm1p-dependent adapter protein for nuclear export of the large ribosomal subunit
25. Composition and functional characterization of yeast 66S ribosome assembly intermediates
26. Identification of a 60S preribosomal particle that is closely linked to nuclear export
27. Thenucle(ol)ar Tif6p and Efl1p are required for a late cytoplasmic step of ribosome synthesis
28. A new view of mRNA export: Separating the wheat from the chaff
29. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
30. Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor
31. The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2)
32. Mex67p, a novel factor for nuclear export, binds to both poly(A)+ RNA and nuclear pores
33. YRA1, an essential Saccharomyces cerevisiae gene, encodes a novel nuclear protein with RNA annealing activity
34. REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export
35. Yra1p, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
36. The yeast hnRNP-Like proteins Yra1p and Yra2p participate in mRNA export through interaction with Mex67p
37. The protein Aly links pre-messenger RNA splicing to nuclear export in metazoans
38. REF proteins mediate the export of spliced and unspliced mRNAs from the nucleus
39. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
40. Pre-mRNA splicing alters mRNP composition: Evidence for stable association of proteins at exon-exon junctions
41. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
42. Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm
43. Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex
44. Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
45. The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
46. The protein Mago provides a link between splicing and mRNA localization
47. Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
48. Drosophila Y14 shuttles to the posterior of the oocyte and is required for oskar mRNA transport
49. Splicing factor Sub2p is required for nuclear mRNA export through its interaction with Yra1p
50. Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly
51. The DECD box putative ATPase Sub2p is an early mRNA export factor
52. The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila
53. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
54. Deletion of Mud2, the yeast homolog of U2AF65, can bypass the requirement for Sub2, an essential spliceosomal ATPase
55. Multiple roles for the yeast Sub2p/yUAP56 gene in splicing
56. Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
57. Splicing is required for rapid and efficient mRNA export in metazoans
58. Messenger RNAs are recruited for nuclear export during transcription
59. Pre-mRNA processing factors are required for nuclear export
60. Quality control of mRNA 3′-end processing is linked to the nuclear exosome
61. Defects in the mRNA export factors Rat7p Gle1p, Mex67p, and Rat8p cause hyperadenylation during 3′-end formation of nascent transcripts
62. A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription
63. HuR and mRNA stability
64. Delineation of mRNA export pathways by the use of cell-permeable peptides
65. Two closely related human nuclear export factors utilize entirely distinct export pathways
66. Molecular mechanism of translocation through nuclear pore complexes during nuclear protein import
67. Nucleocytoplasmic transport: Diffusion channel or phase transition?
68. Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import
69. Proteomic analysis of nucleoporin interacting proteins
70. Kinetics of protein import into isolated Xenopus oocyte nuclei
71. Kinetic analysis of translocation through nuclear pore complexes
72. Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B
73. Structure of the C-terminal FG-nucleoporin binding domain of Tap/NXF1