The DExH/D box protein HEL/UAP56 is essential for mRNA nuclear export in Drosophila

Current Biology

Volumn 11, Issue 21, 2001, Pages 1716-1721

  Gatfield, David ^a   Le Hir, Hervé ^b   Schmitt, Christel ^a   Braun, Isabelle C ^a   Köcher, Thomas ^a   Wilm, Matthias ^a   Izaurralde, Elisa ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; DROSOPHILA; DROSOPHILA MELANOGASTER; MELANOGASTER; VERTEBRATA;

EID: 0035975942     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00532-2     Document Type: Article

References (29)

1. Dbp5p/Rat8p is a yeast nuclear pore-associated DEAD-box protein essential for RNA export
2. Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export
3. Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p
4. Rat8p/Dbp5p is a shuttling transport factor that interacts with rat7p/Nup159p and Gle1p and suppresses the mRNA export defect of xpo1-1 cells
5. The RNA export factor Gle1p is located on the cytoplasmic fibrils of the NPC and physically interacts with the FG-nucleoporin Rip1p, the DEAD-box protein Rat8p/Dbp5p and a new protein Ymr255p
6. A look at messenger RNP moving through the nuclear pore
7. DexD/H box RNA helicases: From generic motors to specific dissociation functions
8. A novel DEAD-box RNA helicase exhibits high sequence conservation from yeast to humans
9. Human RNA helicase A is homologous to the Maleless protein of Drosophila
10. The Maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila
11. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
12. Deletion of MUD2, the yeast homolog of U2AF65, can bypass the requirement for sub2, an essential spliceosomal ATPase
13. Multiple roles for the yeast SUB2/yUAP56 gene in splicing
14. Identification and characterization of yUAP/Sub2p, a yeast homolog of the essential human pre-mRNA splicing factor hUAP56
15. A new enhancer of position-effect variegation in Drosophila melanogaster encodes a putative RNA helicase that binds chromosomes and is regulated by the cell cycle
16. Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways
17. NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila
18. Evolution of dosage compensation in Diptera: The gene maleless implements dosage compensation in Drosophila (Brachycera suborder) but its homolog in Sciara (Nematocera suborder) appears to play no role in dosage compensation
19. RNA splicing is interrupted by heat-shock and is rescued by heat-shock protein synthesis
20. Isolation of a complementary DNA that encodes the mammalian splicing factor SC35
21. The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions
22. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and NMD
23. The Y14 protein communicates to the cytoplasm the position of exon-exon junctions
24. Role of the nonsense-mediated decay factor hUPF3 in the splicing-dependent exon-exon junction complex
25. Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1
26. The DECD box putative ATPase Sub2p is an early mRNA export factor
27. Nucleocytoplasmic transport enters the atomic age
28. TAP, the human homologue of Mex67p, mediates CTE-dependent RNA export from the nucleus