Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

Molecular Cell

Volumn 6, Issue 3, 2000, Pages 673-682

  Kataoka, Naoyuki ^a   Yong, Jeongsik ^a   Kim, V Narry ^a   Velazquez, Francisco ^a,b   Perkinson, Robert A ^a   Wang, Fan ^a   Dreyfuss, Gideon ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b Lankenau Medical Science Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; PROTEIN DERIVATIVE; RNA BINDING PROTEIN;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CELL NUCLEUS; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DROSOPHILA MELANOGASTER; GENE EXPRESSION; GENOME IMPRINTING; HUMAN; HUMAN CELL; INTRON; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; RNA SPLICING; SCHIZOSACCHAROMYCES POMBE; XENOPUS LAEVIS;

ANIMALIA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER; SCHIZOSACCHAROMYCES POMBE; XENOPUS LAEVIS;

EID: 0033634824     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)00065-4     Document Type: Article

References (57)

1. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
2. Control of 3' splice site choice in vivo by ASF/SF2 and hnRNP A1
3. Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs
4. TAP binds to the constitutive transport element (CTE) through a novel RNA-binding motif that is sufficient to promote CTE-dependent RNA export from the nucleus
5. A small element from the Mason-Pfizer monkey virus genome makes human immunodeficiency virus type 1 expression and replication Rev-independent
6. Conserved structures and diversity of functions of RNA-binding proteins
7. Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors
8. A splicing-dependent regulatory mechanism that detects translation signals
9. Messenger RNA transport and HIV rev regulation
10. Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance
11. Isolation of the heterogeneous nuclear RNA-ribonucleoprotein complex (hnRNP): A unique supra-molecular assembly
12. Connections between the processing and nuclear export of mRNA: Evidence for an export license?
13. Ran-binding protein 5 (RanBP5) is related to the nuclear transport factor importin-beta but interacts differently with RanBP1
14. hnRNP proteins and the biogenesis of mRNA
15. The SMN-SIP1 complex has an essential role in spliceosomal snRNPP biogenesis
16. The superfamily of arginine/serine-rich splicing factors
17. Transport between the cell nucleus and the cytoplasm
18. TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus
19. Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors
20. hnRNP A2 selectively binds the cytoplasmic transport sequence of myelin basic protein mRNA
21. Importin beta, transportin, RanBP5 and RanBP7 mediate nuclear import of ribosomal proteins in mammalian cells
22. The human Tap protein is a nuclear mRNA export factor that contains novel RNA-binding and nucleocytoplasmic transport sequences
23. The Mex67p-mediated nuclear mRNA export pathway is conserved from yeast to human
24. Transportin-SR, a nuclear import receptor for SR proteins
25. hnRNP complexes: Composition, structure, and function
26. The cis-acting RNA trafficking signal from myelin basic protein mRNA and its cognate trans-acting ligand hnRNP A2 enhance cap-dependent translation
27. Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts
28. Structure and function in the nucleus
29. Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm
30. T cell receptor (TCR) mini-gene mRNA expression regulated by nonsense codons: A nuclear-associated translation-like mechanism
31. Splicing is required for rapid and efficient mRNA export in metazoans
32. Defects in RNA splicing and the consequence of shortened translational reading frame
33. Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA
34. Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2
35. A nuclear export signal in hnRNP A1: A signal-mediated, temperature-dependent nuclear protein export pathway
36. The K nuclear shuttling domain: A novel signal for nuclear import and nuclear export in the hnRNP K protein
37. The cellular organization of gene expression
38. The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signals
39. Transport of proteins and RNAs in and out of the nucleus
40. A human RNA helicase-like protein, HRH1, facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome
41. Preferential excision of the 5' proximal intron from mRNA precursors with two introns as mediated by the cap structure
42. mRNA silencing in erythroid differentiation: hnRNP K and hnRNP E1 regulate15-lipoxygenase translation from the 3' end
43. Cytoplasmic regulatory functions of the KH-domain proteins hnRNPs K and E1/E2
44. A novel function for SMN, the spinal muscular atrophy disease gene product, in pre-mRNA splicing
45. Shuttling of pre-mRNA binding proteins between nucleus and cytoplasm
46. hnRNP proteins: Localization and transport between nucleus and cytoplasm
47. Immunopurification of heterogeneous nuclear ribonucleoprotein particles reveals an assortment of RNA-binding proteins
48. The HIV-1 Rev protein
49. A distinct nuclear import pathway used by ribosomal proteins
50. Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores
51. Transportin-mediated nuclear import of heterogeneous nuclear RNP proteins
52. Nuclear RNA export
53. General RNA binding proteins render translation cap dependent
54. A pre-mRNA-binding protein accompanies the RNA from the gene through the nuclear pores and into polysomes
55. The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo
56. Intron function in the nonsense-mediated decay of beta-globin mRNA: Indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm
57. Continuous propagation of RRE(-) and Rev(-)RRE(-) human immunodeficiency virus type 1 molecular clones containing a cis-acting element of simian retrovirus type 1 in human peripheral blood lymphocytes