메뉴 건너뛰기




Volumn 260, Issue 3, 1996, Pages 422-431

The 1.6 Å resolution crystal structure of nuclear transport factor 2 (NTF2)

Author keywords

Hydrophobic cavity; Interactions; Nuclear import; Nucleoporin p62; Ran

Indexed keywords

CARRIER PROTEIN; GUANOSINE TRIPHOSPHATASE; HYDROLYASE; NUCLEOPORIN; MEMBRANE PROTEIN; NTF2 PROTEIN, RAT; NUCLEAR PORE PROTEIN P62; NUCLEAR PROTEIN; NUCLEOCYTOPLASMIC TRANSPORT PROTEIN; RAN PROTEIN; SCYTALONE DEHYDRATASE;

EID: 0030593377     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1996.0411     Document Type: Article
Times cited : (123)

References (47)
  • 2
    • 0028217405 scopus 로고
    • Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope
    • Adam, E. J. H. & Adam, S. A. (1994). Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope. J. Cell Biol. 125, 547-555.
    • (1994) J. Cell Biol. , vol.125 , pp. 547-555
    • Adam, E.J.H.1    Adam, S.A.2
  • 3
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its derivatives
    • Boguski, M. S. & McCormick, F. (1993). Proteins regulating Ras and its derivatives. Nature, 366, 643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 4
    • 0026597444 scopus 로고
    • Free R value: A novel statistical quality for assessing the accuracy of crystal structures
    • Brünger, A. T. (1992). Free R value: a novel statistical quality for assessing the accuracy of crystal structures. Nature, 355, 472-474.
    • (1992) Nature , vol.355 , pp. 472-474
    • Brünger, A.T.1
  • 5
    • 0028900866 scopus 로고
    • Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: Binding of nucleoporin p54 to the rod domain of p62
    • Buss, F. & Stewart, M. (1995). Macromolecular interactions in the nucleoporin p62 complex of rat nuclear pores: binding of nucleoporin p54 to the rod domain of p62. J. Cell Biol. 128, 251-261.
    • (1995) J. Cell Biol. , vol.128 , pp. 251-261
    • Buss, F.1    Stewart, M.2
  • 6
    • 0028345077 scopus 로고
    • Role of different domains in the self-association of rat nucleoporin p62
    • Buss, F., Kent, H. M., Stewart, M., Bailer, S. M. & Hanover, J. A. (1994). Role of different domains in the self-association of rat nucleoporin p62. J. Cell Sci. 107, 631-638.
    • (1994) J. Cell Sci. , vol.107 , pp. 631-638
    • Buss, F.1    Kent, H.M.2    Stewart, M.3    Bailer, S.M.4    Hanover, J.A.5
  • 7
    • 0028915743 scopus 로고
    • GTPase cascades choreographing cellular behaviour: Movement, morphogenesis and more
    • Chant, J. & Stowers, L. (1995). GTPase cascades choreographing cellular behaviour: movement, morphogenesis and more. Cell, 81, 1-4.
    • (1995) Cell , vol.81 , pp. 1-4
    • Chant, J.1    Stowers, L.2
  • 8
    • 0028103275 scopus 로고
    • The CCP4 suite: Programmes for protein crystallography
    • Collaborative Computational Project, Number 4 (1994). The CCP4 suite: programmes for protein crystallography. Acta Crystallog. sect. D, 50, 760-763.
    • (1994) Acta Crystallog. Sect. D , vol.50 , pp. 760-763
  • 9
    • 0029060051 scopus 로고
    • The nuclear pore complex
    • Davis, L. A. (1995). The nuclear pore complex. Annu. Rev. Biochem. 64, 865-896.
    • (1995) Annu. Rev. Biochem. , vol.64 , pp. 865-896
    • Davis, L.A.1
  • 10
    • 0022458304 scopus 로고
    • Identification and characterisation of a nuclear pore complex protein
    • Davis, L. I. & Blobel, G. (1986). Identification and characterisation of a nuclear pore complex protein. Cell, 45, 699-709.
    • (1986) Cell , vol.45 , pp. 699-709
    • Davis, L.I.1    Blobel, G.2
  • 11
    • 0025949412 scopus 로고
    • Nuclear targetting sequences - A consensus?
    • Dingwall, C. & Laskey, R. A. (1991). Nuclear targetting sequences - a consensus? Trends Biochem. Sci. 16, 478-481.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 478-481
    • Dingwall, C.1    Laskey, R.A.2
  • 12
    • 0021717131 scopus 로고
    • Movement of a karyophilic protein through the nuclear pores of oocytes
    • Feldherr, C., Kallenbach, E. & Schultz, N. (1984). Movement of a karyophilic protein through the nuclear pores of oocytes. J. Cell Biol. 99, 2216-2222.
    • (1984) J. Cell Biol. , vol.99 , pp. 2216-2222
    • Feldherr, C.1    Kallenbach, E.2    Schultz, N.3
  • 13
  • 14
    • 0027937653 scopus 로고
    • Isolation of a protein that is essential for the first step of nuclear protein import
    • Görlich, D., Prehn, S., Laskey, R. A. & Hartmann, E. (1994). Isolation of a protein that is essential for the first step of nuclear protein import. Cell, 79, 767-778.
    • (1994) Cell , vol.79 , pp. 767-778
    • Görlich, D.1    Prehn, S.2    Laskey, R.A.3    Hartmann, E.4
  • 15
    • 0029278621 scopus 로고
    • Two different subunits of importin co-operate to recognise nuclear localisation signals and bind them to the nuclear envelope
    • Görlich, D., Kostka, H., Kraft, R., Dingwall, C., Laskey, R. A., Hartmann, E. & Prehn, S. (1995a). Two different subunits of importin co-operate to recognise nuclear localisation signals and bind them to the nuclear envelope. Curr. Biol. 5, 383-392.
    • (1995) Curr. Biol. , vol.5 , pp. 383-392
    • Görlich, D.1    Kostka, H.2    Kraft, R.3    Dingwall, C.4    Laskey, R.A.5    Hartmann, E.6    Prehn, S.7
  • 16
    • 0029059548 scopus 로고
    • Distinct functions for the two importin subunits in nuclear protein import
    • Görlich, D., Vogel, F., Mills, A. D., Hartmann, E. & Laskey, R. A. (1995b). Distinct functions for the two importin subunits in nuclear protein import. Nature, 377, 246-248.
    • (1995) Nature , vol.377 , pp. 246-248
    • Görlich, D.1    Vogel, F.2    Mills, A.D.3    Hartmann, E.4    Laskey, R.A.5
  • 18
    • 0028786983 scopus 로고
    • Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex
    • Guan, T., Müller, S., Klier, G., Pante, N., Blevitt, J. M., Haner, M., Paschal, B. M., Aebi, U. & Gerace, L. (1995). Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Mol. Biol. Cell, 6, 1591-1603.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1591-1603
    • Guan, T.1    Müller, S.2    Klier, G.3    Pante, N.4    Blevitt, J.M.5    Haner, M.6    Paschal, B.M.7    Aebi, U.8    Gerace, L.9
  • 19
  • 20
    • 84889120137 scopus 로고
    • Improved methods for building protein models in electron density maps and for locating errors in these models
    • Jones, T. A., Zou, J.-Y., Cowan, S. W. & Kjeldgaard, M. (1991). Improved methods for building protein models in electron density maps and for locating errors in these models. Acta Crystallog. sect. A, 47, 110-119.
    • (1991) Acta Crystallog. Sect. A , vol.47 , pp. 110-119
    • Jones, T.A.1    Zou, J.-Y.2    Cowan, S.W.3    Kjeldgaard, M.4
  • 21
    • 0029995424 scopus 로고    scopus 로고
    • Crystallization and preliminary X-ray diffraction analysis of nuclear transport factor 2 (NTF2)
    • Kent, H. M., Clarkson, W. D., Bullock, T. L. & Stewart, M. (1996). Crystallization and preliminary X-ray diffraction analysis of nuclear transport factor 2 (NTF2). J. Struct. Biol. 116, 325-328.
    • (1996) J. Struct. Biol. , vol.116 , pp. 325-328
    • Kent, H.M.1    Clarkson, W.D.2    Bullock, T.L.3    Stewart, M.4
  • 22
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature, 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.1
  • 23
    • 0028774336 scopus 로고
    • Crystal structure of scytalone dehydratase - A disease determinant of the rice pathogen, Magnaporthe gisea
    • Lundqvist, T., Rice, J., Hodge, C. N., Basarab, G. S., Pierce, J. & Lundqvist, Y. (1994). Crystal structure of scytalone dehydratase - a disease determinant of the rice pathogen, Magnaporthe gisea. Structure, 2, 937-944.
    • (1994) Structure , vol.2 , pp. 937-944
    • Lundqvist, T.1    Rice, J.2    Hodge, C.N.3    Basarab, G.S.4    Pierce, J.5    Lundqvist, Y.6
  • 24
    • 0029042717 scopus 로고
    • Mechanisms of nuclear protein import
    • Melchior, F. & Gerace, L. (1995). Mechanisms of nuclear protein import. Curr. Opin. Cell Biol. 7, 310-318.
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 310-318
    • Melchior, F.1    Gerace, L.2
  • 25
    • 0028170744 scopus 로고
    • Purification of a Ran-interacting protein that is required for protein import into the nucleus
    • Moore, M. S. & Blobel, G. (1994). Purification of a Ran-interacting protein that is required for protein import into the nucleus. Proc. Natl Acad. Sci. USA, 91, 10212-10216.
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , pp. 10212-10216
    • Moore, M.S.1    Blobel, G.2
  • 26
    • 0028983494 scopus 로고
    • 2 subunit binds nuclear localisation signal and β subunit interacts with peptide repeat-containing nucleoporins
    • 2 subunit binds nuclear localisation signal and β subunit interacts with peptide repeat-containing nucleoporins. Proc. Natl Acad. Sci. USA, 92, 6532-6536.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 6532-6536
    • Moroianu, J.1    Hijkata, M.2    Blobel, G.3    Radu, A.4
  • 29
    • 0028316365 scopus 로고
    • Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level
    • Pante, N. & Aebi, U. (1994). Towards understanding the three-dimensional structure of the nuclear pore complex at the molecular level. Curr. Opin. Struct. Biol. 4, 187-196.
    • (1994) Curr. Opin. Struct. Biol. , vol.4 , pp. 187-196
    • Pante, N.1    Aebi, U.2
  • 30
    • 0029027836 scopus 로고
    • Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62
    • Paschal, B. M. & Gerace, L. (1995). Identification of NTF2, a cytosolic factor for nuclear import that interacts with nuclear pore complex protein p62. J. Cell Biol. 129, 925-937.
    • (1995) J. Cell Biol. , vol.129 , pp. 925-937
    • Paschal, B.M.1    Gerace, L.2
  • 31
    • 4244058852 scopus 로고
    • NTF2 interacts with the GDP-bound form of Ran/TC4 and is required for viability in S. cerevisiae
    • Paschal, B. M., Fritze, C. & Gerace, L. (1995). NTF2 interacts with the GDP-bound form of Ran/TC4 and is required for viability in S. cerevisiae. Mol. Biol. Cell, 6, 82a.
    • (1995) Mol. Biol. Cell , vol.6
    • Paschal, B.M.1    Fritze, C.2    Gerace, L.3
  • 32
    • 0028950991 scopus 로고
    • Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins
    • Radu, A., Blobel, G. & Moore, M. S. (1995a). Identification of a protein complex that is required for nuclear protein import and mediates docking of import substrate to distinct nucleoporins. Proc. Natl Acad. Sci. USA, 92, 1769-1773.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 1769-1773
    • Radu, A.1    Blobel, G.2    Moore, M.S.3
  • 33
    • 0029021567 scopus 로고
    • The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
    • Radu, A., Moore, M. S. & Blobel, G. (1995b). The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell, 81, 215-222.
    • (1995) Cell , vol.81 , pp. 215-222
    • Radu, A.1    Moore, M.S.2    Blobel, G.3
  • 34
    • 0025247954 scopus 로고
    • Correlation between structure and mass distribution of nuclear pore complex and of distinct pore complex components
    • Reichelt, R., Holzenburg, A., Buhle, E. L., Jarnik, M. & Aebi, U. (1990). Correlation between structure and mass distribution of nuclear pore complex and of distinct pore complex components. J. Cell Biol. 110, 883-894.
    • (1990) J. Cell Biol. , vol.110 , pp. 883-894
    • Reichelt, R.1    Holzenburg, A.2    Buhle, E.L.3    Jarnik, M.4    Aebi, U.5
  • 35
    • 0028355757 scopus 로고
    • Effects of mutated Ran/TC4 protein on cell cycle progression
    • Ren, M., Coutavas, E., D'Eustachio, P. & Rush, M. G. (1994). Effects of mutated Ran/TC4 protein on cell cycle progression. Mol. Cell. Biol. 14, 4216-4224.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4216-4224
    • Ren, M.1    Coutavas, E.2    D'Eustachio, P.3    Rush, M.G.4
  • 36
    • 0028834428 scopus 로고
    • Protein import into nuclei: Association and dissociation reactions involving transport substrate, transport factors, and nucleoporins
    • Rexach, M. & Blobel, G. (1995). Protein import into nuclei: association and dissociation reactions involving transport substrate, transport factors, and nucleoporins. Cell, 83, 683-692.
    • (1995) Cell , vol.83 , pp. 683-692
    • Rexach, M.1    Blobel, G.2
  • 37
    • 0023852444 scopus 로고
    • Nuclear protein migration involves two steps: Rapid binding at the nuclear envelope followed by slower translocation through the nuclear pores
    • Richardson, W. D., Mills, A. D., Dilworth, S. M., Laskey, R. A. & Dingwall, C. (1988). Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through the nuclear pores. Cell, 52, 655-664.
    • (1988) Cell , vol.52 , pp. 655-664
    • Richardson, W.D.1    Mills, A.D.2    Dilworth, S.M.3    Laskey, R.A.4    Dingwall, C.5
  • 38
    • 0027989786 scopus 로고
    • Pores for thought: Nuclear pore complex proteins
    • Rout, M. P. & Wente, S. R. (1994). Pores for thought: nuclear pore complex proteins. Trends Cell Biol. 4, 357-365.
    • (1994) Trends Cell Biol. , vol.4 , pp. 357-365
    • Rout, M.P.1    Wente, S.R.2
  • 39
    • 0028929866 scopus 로고
    • Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form
    • Scheffzek, K., Klebe, C., Fritz-Wolf, K., Kabsch, W. & Wittinghofer, A. (1995). Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form. Nature, 374, 378-381.
    • (1995) Nature , vol.374 , pp. 378-381
    • Scheffzek, K.1    Klebe, C.2    Fritz-Wolf, K.3    Kabsch, W.4    Wittinghofer, A.5
  • 40
    • 0029089597 scopus 로고
    • Nucleocytoplasmic transport: Factors and mechanisms
    • Simos, G. & Hurt, E. C. (1995). Nucleocytoplasmic transport: factors and mechanisms. FEBS Letters, 369, 107-112.
    • (1995) FEBS Letters , vol.369 , pp. 107-112
    • Simos, G.1    Hurt, E.C.2
  • 41
    • 0025314491 scopus 로고
    • Primary sequence and heterologous expression of nuclear pore glycoprotein p62
    • Starr, C. M., D'Onofrio, M., Park, M. K. & Hanover, J. A. (1990). Primary sequence and heterologous expression of nuclear pore glycoprotein p62. J. Cell Biol. 110, 1861-1871.
    • (1990) J. Cell Biol. , vol.110 , pp. 1861-1871
    • Starr, C.M.1    D'Onofrio, M.2    Park, M.K.3    Hanover, J.A.4
  • 42
    • 0029981666 scopus 로고    scopus 로고
    • Nuclear pores and macromolecular assemblies involved in nucleocytoplasmic transport
    • Stewart, M. & Clarkson, W. D. (1996). Nuclear pores and macromolecular assemblies involved in nucleocytoplasmic transport. Curr. Opin. Struct. Biol. 6, 162-165.
    • (1996) Curr. Opin. Struct. Biol. , vol.6 , pp. 162-165
    • Stewart, M.1    Clarkson, W.D.2
  • 43
    • 0025295680 scopus 로고
    • Association of gold-labelled nucleoplasmin with the centres of ring components of Xenopus oocyte nuclear pore complexes
    • Stewart, M., Whytock, S. & Mills, A. D. (1990). Association of gold-labelled nucleoplasmin with the centres of ring components of Xenopus oocyte nuclear pore complexes. J. Mol. Biol. 213, 575-582.
    • (1990) J. Mol. Biol. , vol.213 , pp. 575-582
    • Stewart, M.1    Whytock, S.2    Mills, A.D.3
  • 45
    • 0028790401 scopus 로고
    • Taking from the cytoplasm and giving to the pore: Soluble transport factors in nuclear protein import
    • Sweet, D. J. & Gerace, L. (1995). Taking from the cytoplasm and giving to the pore: soluble transport factors in nuclear protein import. Trends Cell Biol. 5, 444-447.
    • (1995) Trends Cell Biol. , vol.5 , pp. 444-447
    • Sweet, D.J.1    Gerace, L.2
  • 46
    • 84913050729 scopus 로고
    • An efficient general-purpose least-squares refinement program for macromolecular structures
    • Tronrud, D. E., TenEyck, L. F. & Mathews, B. W. (1987). An efficient general-purpose least-squares refinement program for macromolecular structures. Acta Crystallog. sect. A, 43, 489-501.
    • (1987) Acta Crystallog. Sect. A , vol.43 , pp. 489-501
    • Tronrud, D.E.1    TenEyck, L.F.2    Mathews, B.W.3
  • 47
    • 0025740753 scopus 로고
    • The role of Ras protein: A model for a universal molecular switch
    • Wittinghofer, A. & Pai, E. (1991). The role of Ras protein: a model for a universal molecular switch. Trends Biochem. Sci. 16, 383-387.
    • (1991) Trends Biochem. Sci. , vol.16 , pp. 383-387
    • Wittinghofer, A.1    Pai, E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.