Multiple roles for the yeast SUB2/yUAP56 gene in splicing

Genes and Development

Volumn 15, Issue 1, 2001, Pages 36-41

  Libri, D ^a   Graziani, N ^a   Saguez, C ^a   Boulay, J ^a  

^a CNRS   (France)

Author keywords

Helicase; hUAP56; Prespliceosome; SPAC17G6.14c; Splicing; SUB2; U2snRNP

Indexed keywords

GENE PRODUCT; SMALL NUCLEAR RIBONUCLEOPROTEIN; SUB2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; GENE ISOLATION; GENE SEQUENCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SCHIZOSACCHAROMYCES POMBE; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; SPLICEOSOME;

AMINO ACID SEQUENCE; CLONING, MOLECULAR; FUNGAL PROTEINS; GENE DELETION; HUMANS; MOLECULAR SEQUENCE DATA; RECOMBINANT PROTEINS; RNA SPLICING; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TRANSCRIPTION, GENETIC;

MAMMALIA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES POMBE;

EID: 0035180388     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.852101     Document Type: Article

References (25)

1. A link between secretion and pre-mRNA processing defects in Saccharomyces cerevisiae and the identification of a novel splicing gene
2. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families
3. U2AF65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
4. A set of vectors with a tetracycline-regulatable promoter system for modulated gene expression in Saccharomyces cerevisiae
5. A comprehensive biochemical and genetic analysis of the yeast U1 snRNP reveals live novel proteins
6. Identification of Prp40, a novel essential yeast splicing factor associated with the U1 small nuclear ribonucleoprotein particle
7. Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
8. Disruption of six Saccharomyces cerevisiae genes from chromosome IV and basic phenotypic analysis of deletion mutants
9. Splicing of precursors to mRNAs by the spliceosome
10. Identification of novel genes required for yeast pre-mRNA splicing by means of cold-sensitive mutations
11. Transcriptional pulse-chase analysis reveals a role for a novel snRNP-associated protein in the manufacture of spliceosomal snRNPs
12. The Saccharomyces cerevisiae Prp5 protein has RNA-dependent ATPase activity with specificity for U2 small nuclear RNA
13. Interaction of the U1 snRNP with nonconserved intronic sequences affects 5′ splice site selection
14. RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2
15. Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA
16. Transient interaction of BBP/ScSF1 and Mud2 with the splicing machinery affects the kinetics of spliceosome assembly
17. A dual role for BBP/ScSF1 in nuclear pre-mRNA retention and splicing
18. Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
19. The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA
20. Mechanical devices of the spliceosome: Motors, clocks, springs, and things
21. An RNA switch at the 5′ splice site requires ATP and the DEAD box protein Prp28p
22. Identification and characterization of a yeast homolog of U1 snRNP-specific protein C
23. A novel role for a U5 snRNP protein in 3′ splice site selection
24. New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae
25. In vitro studies of the Prp9.Prp11.Prp21 complex indicate a pathway for U2 small nuclear ribonucleoprotein activation