메뉴 건너뛰기




Volumn 19, Issue 24, 2000, Pages 6860-6869

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

Author keywords

Exon exon junctions; mRNA; Nonsense mediated decay; Nucleocytoplasmic transport; Spliceosome

Indexed keywords

MESSENGER RNA; NUCLEOTIDE; PROTEIN; PROTEIN DEK; PROTEIN REF; PROTEIN RNPS1; PROTEIN SRM160; PROTEIN Y14; RIBONUCLEASE; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG;

EID: 0034672093     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.24.6860     Document Type: Article
Times cited : (740)

References (52)
  • 2
    • 17044441683 scopus 로고    scopus 로고
    • The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates
    • (2000) RNA , vol.6 , pp. 136-158
    • Bachi, A.1
  • 8
    • 0028215301 scopus 로고
    • RNA binding specificity of hnRNP A1: Significance of hnRNP A1 high-affinity binding sites in premRNA splicing
    • (1994) EMBO J. , vol.13 , pp. 1197-1204
    • Burd, C.G.1    Dreyfuss, G.2
  • 10
    • 0033179776 scopus 로고    scopus 로고
    • Allele-specific genetic interactions between Prp8 and RNA active site residues suggest a function for Prp8 at the catalytic core of the spliceosome
    • (1999) Genes Dev. , vol.13 , pp. 1970-1982
    • Collins, C.A.1    Guthrie, C.2
  • 16
    • 0028360767 scopus 로고
    • A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
    • (1994) EMBO J. , vol.13 , pp. 3356-3367
    • Gozani, O.1    Patton, J.G.2    Reed, R.3
  • 17
    • 0030044836 scopus 로고    scopus 로고
    • Evidence that sequence-independent binding of highly conserved U2 snRNP proteins upstream of the branch site is required for assembly of spliceosomal complex A
    • (1996) Genes Dev. , vol.10 , pp. 233-243
    • Gozani, O.1    Feld, R.2    Reed, R.3
  • 30
    • 0029330286 scopus 로고
    • When cells stop making sense: Effects of nonsense codons on RNA metabolism in vertebrate cells
    • (1995) RNA , vol.1 , pp. 453-465
    • Maquat, L.E.1
  • 31
    • 0002650836 scopus 로고    scopus 로고
    • Nonsense-mediated RNA decay in mammalian cells: A splicing-dependent means to down-regulate the levels of mRNAs that prematurely terminate translation
    • Sonenberg,N., Hershey,J.W.B. and Mathews,M.B. (eds), Translational Control of Gene Expression. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
    • (2000) , pp. 827-868
    • Maquat, L.E.1
  • 33
    • 0034710286 scopus 로고    scopus 로고
    • The acute myeloid leukemia-associated protein DEK forms a splicing-dependent interaction with exon-product complexes
    • (2000) J. Cell Biol. , vol.150 , pp. 309-320
    • McGarvey, T.1
  • 34
    • 0001863161 scopus 로고    scopus 로고
    • Uses of site-specifically modified RNAs constructed by RNA ligation
    • Smith,C.W.J. (ed.), RNA-Protein Interactions: A Practical Approach. IRL Press, Oxford, UK
    • (1998) , pp. 75-108
    • Moore, M.J.1    Query, C.C.2
  • 43
    • 0141469976 scopus 로고    scopus 로고
    • Yralp, a conserved nuclear RNA-binding protein, interacts directly with Mex67p and is required for mRNA export
    • (2000) EMBO J. , vol.19 , pp. 410-420
    • Strasser, K.1    Hurt, E.2
  • 46
    • 0029031713 scopus 로고
    • Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA
    • (1995) EMBO J. , vol.14 , pp. 2602-2612
    • Teigelkamp, S.1    Newman, A.J.2    Beggs, J.D.3
  • 49
    • 0025817865 scopus 로고
    • A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylation
    • (1991) Cell , vol.66 , pp. 759-768
    • Wahle, E.1
  • 51
    • 0031870169 scopus 로고    scopus 로고
    • Intron function in the nonsense-mediated decay of β-globin mRNA: Indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm
    • (1998) RNA , vol.4 , pp. 801-815
    • Zhang, J.1    Sun, X.2    Qian, Y.3    Maquat, L.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.