Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with trail resistance

Journal of Biological Chemistry

Volumn 276, Issue 42, 2001, Pages 38361-38369

  Thakkar, Hitesh ^a   Chen, Xufeng ^a   Tyan, Frazier ^a   Gim, Suzanna ^a   Robinson, Heather ^a   Lee, Calvin ^a   Pandey, Sanjay K ^b   Nwokorie, Chichi ^a   Onwudiwe, Nneka ^a   Srivastava, Rakesh K ^a,c  

^a UNIVERSITY OF MARYLAND SCHOOL OF PHARMACY   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMOTHERAPY; DRUG THERAPY; ENZYME INHIBITION; ENZYME KINETICS; GENETIC ENGINEERING; ONCOLOGY;

CELLULAR RESISTANCE;

ENZYMES;

2 MORPHOLINO 8 PHENYLCHROMONE; CYCLOHEXIMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; WORTMANNIN; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; AKT1 PROTEIN, HUMAN; ANDROSTANE DERIVATIVE; APOPTOSIS REGULATORY PROTEIN; BCL2L1 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; CASPASE 8; CASPASE 9; CHROMONE DERIVATIVE; ENZYME INHIBITOR; MEMBRANE PROTEIN; MORPHOLINE DERIVATIVE; ONCOPROTEIN; PROTEIN BCL X; PROTEIN SERINE THREONINE KINASE; RECOMBINANT PROTEIN; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER RESISTANCE; CELL SURVIVAL; CELL TRANSFORMATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; CELL CULTURE; CELL FRACTIONATION; CELL MEMBRANE; DOMINANT GENE; DOWN REGULATION; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; GENETICS; MALE; METABOLISM; MITOCHONDRION; PHYSIOLOGY; PROSTATE TUMOR; RETRACTED ARTICLE; TIME; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-X PROTEIN; BLOTTING, WESTERN; CASPASE 8; CASPASE 9; CASPASES; CELL MEMBRANE; CELL SURVIVAL; CHROMONES; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENES, DOMINANT; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; MORPHOLINES; PROSTATIC NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINANT PROTEINS; SUBCELLULAR FRACTIONS; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035914394     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M103321200     Document Type: Article

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