-
1
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering, B. M. Th. & Coffer, P. J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 376, 599-602 (1995).
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.Th.1
Coffer, P.J.2
-
2
-
-
0029079275
-
The protein kinase encoded by the akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
-
Franke, T. F. et al. The protein kinase encoded by the akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase. Cell 81, 727-736 (1995).
-
(1995)
Cell
, vol.81
, pp. 727-736
-
-
Franke, T.F.1
-
3
-
-
0032513053
-
Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence
-
Cichy, S. B. et al. Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence. J. Biol. Chem. 273, 6482-6487 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6482-6487
-
-
Cichy, S.B.1
-
4
-
-
14444286453
-
Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt
-
Wang, D. & Sul, H. S. Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt. J. Biol. Chem. 273, 25420-25426 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25420-25426
-
-
Wang, D.1
Sul, H.S.2
-
5
-
-
0030659557
-
The forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg, S. et al. The forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389, 994-999 (1997).
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
-
6
-
-
0030657540
-
daf-16: And HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
-
Lin, K., Dorman, J. B., Rodan, A. & Kenyon, C. daf-16: and HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278, 1319-1322 (1997).
-
(1997)
Science
, vol.278
, pp. 1319-1322
-
-
Lin, K.1
Dorman, J.B.2
Rodan, A.3
Kenyon, C.4
-
7
-
-
0030813398
-
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabiditis elegans
-
Kimura, K. D., Tissenbaum, H. A., Liu, Y. & Ruvkun, G. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabiditis elegans. Science 277, 942-946 (1997).
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
8
-
-
0029768753
-
Phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris, J. Z., Tissenbaum, H. A. & Ruvkun, G. A. Phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382, 536-539 (1996).
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.A.3
-
9
-
-
0031031378
-
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukaemias with a t(X;11)(q13;q23)
-
Borkhardt, A. et al. Cloning and characterization of AFX, the gene that fuses to MLL in acute leukaemias with a t(X;11)(q13;q23). Oncogene 14, 195-202 (1997).
-
(1997)
Oncogene
, vol.14
, pp. 195-202
-
-
Borkhardt, A.1
-
10
-
-
0030590875
-
Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase
-
Alessi, D. R., Caudwell, F. B., Andjelkovic, M., Hemmings, B. A. & Cohen, P. Molecular basis for the substrate specificity of protein kinase B; comparison with MAPKAP kinase-1 and p70 S6 kinase. FEBS Lett. 399, 333-338 (1996).
-
(1996)
FEBS Lett.
, vol.399
, pp. 333-338
-
-
Alessi, D.R.1
Caudwell, F.B.2
Andjelkovic, M.3
Hemmings, B.A.4
Cohen, P.5
-
11
-
-
0032557646
-
Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation
-
Van Weeren, P. C., de Bruyn, K. M., de Vries-Smits, A. M., van Lint, J. & Burgering, B. M. Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. J. Biol. Chem. 273, 13150-13156 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13150-13156
-
-
Van Weeren, P.C.1
De Bruyn, K.M.2
De Vries-Smits, A.M.3
Van Lint, J.4
Burgering, B.M.5
-
12
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham, B. et al. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell Biol. 14, 4902-4911 (1994).
-
(1994)
Mol. Cell Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
-
13
-
-
0028670126
-
The role of p21 ras in receptor tyrosine kinase signalling
-
Pronk, G. J. & Bos, J. L. The role of p21 ras in receptor tyrosine kinase signalling. Biochim. Biophys. Acta 1198, 131-147 (1994).
-
(1994)
Biochim. Biophys. Acta
, vol.1198
, pp. 131-147
-
-
Pronk, G.J.1
Bos, J.L.2
-
14
-
-
0025932251
-
Two dominant inhibitory mutants of p2 Iras interfere with insulin-induced gene expression
-
Medema, R. H., Wubbolts, R. & Bos, J. L. Two dominant inhibitory mutants of p2 Iras interfere with insulin-induced gene expression. Mol. Cell Biol. 11, 5963-5967 (1991).
-
(1991)
Mol. Cell Biol.
, vol.11
, pp. 5963-5967
-
-
Medema, R.H.1
Wubbolts, R.2
Bos, J.L.3
-
15
-
-
0031028730
-
Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB
-
Kauffmann-Zeh, A. et al. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB. Nature 385, 544-548 (1997).
-
(1997)
Nature
, vol.385
, pp. 544-548
-
-
Kauffmann-Zeh, A.1
-
16
-
-
0030022174
-
Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation
-
Urano, T., Emkey, R. & Feig, L. A. Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation. EMBO J. 15, 810-816 (1996).
-
(1996)
EMBO J.
, vol.15
, pp. 810-816
-
-
Urano, T.1
Emkey, R.2
Feig, L.A.3
-
17
-
-
0028917954
-
Regulation of Ras-mediated signalling: More than one way to skin a cat
-
Burgering, B. M. & Bos, J. L. Regulation of Ras-mediated signalling: more than one way to skin a cat. Trends Biochem. Sci. 20, 18-22 (1995).
-
(1995)
Trends Biochem. Sci.
, vol.20
, pp. 18-22
-
-
Burgering, B.M.1
Bos, J.L.2
-
18
-
-
0030728532
-
Stimulation of gene induction and cell growth by the ras effector RIf
-
Wolthuis, R. M. F., de Ruiter, N. D., Cool, R. H. & Bos, J. L. Stimulation of gene induction and cell growth by the ras effector RIf. EMBO J. 16, 6748-6761 (1997).
-
(1997)
EMBO J.
, vol.16
, pp. 6748-6761
-
-
Wolthuis, R.M.F.1
De Ruiter, N.D.2
Cool, R.H.3
Bos, J.L.4
-
19
-
-
0028272507
-
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
-
Leevers, S. J., Paterson, H. F. & Marshall, C. J. Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane. Nature 369, 411-414 (1994).
-
(1994)
Nature
, vol.369
, pp. 411-414
-
-
Leevers, S.J.1
Paterson, H.F.2
Marshall, C.J.3
-
20
-
-
0029831581
-
RaIGDS-like factor (RIf) is a novel Ras and Rap1A-associating protein
-
Wolthuis, R. M. F. et al. RaIGDS-like factor (RIf) is a novel Ras and Rap1A-associating protein. Oncogene 13, 353-362 (1996).
-
(1996)
Oncogene
, vol.13
, pp. 353-362
-
-
Wolthuis, R.M.F.1
-
21
-
-
0027967521
-
Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function
-
Unterman, T. G. et al. Hepatocyte nuclear factor-3 (HNF-3) binds to the insulin response sequence in the IGF binding protein-1 (IGFBP-1) promoter and enhances promoter function. Biochem. Biophys. Res. Commun. 203, 1835-1841 (1994).
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.203
, pp. 1835-1841
-
-
Unterman, T.G.1
-
22
-
-
0028860340
-
Hepatic nuclear factor-3 and hormone regulated expression of the PEPCK and IGFBP-1 genes
-
O'Brien, R. M. et al. Hepatic nuclear factor-3 and hormone regulated expression of the PEPCK and IGFBP-1 genes. Mol. Cell Biol. 15, 1747-1758 (1995).
-
(1995)
Mol. Cell Biol.
, vol.15
, pp. 1747-1758
-
-
O'Brien, R.M.1
-
23
-
-
0029791789
-
The CR1 and CR3 domains of the adenovirus type 5 EIA proteins can independently mediate activation of ATF-2
-
Duyndam, M. C., van Dam, H., van der Eb, A. J. & Zantema, A. The CR1 and CR3 domains of the adenovirus type 5 EIA proteins can independently mediate activation of ATF-2. J. Virol. 70, 5852-5859 (1996).
-
(1996)
J. Virol.
, vol.70
, pp. 5852-5859
-
-
Duyndam, M.C.1
Van Dam, H.2
Van Der Eb, A.J.3
Zantema, A.4
-
24
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andjelkovic, M. et al. Role of translocation in the activation and function of protein kinase B. J. Biol. Chem. 272, 31515-31524 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 31515-31524
-
-
Andjelkovic, M.1
-
25
-
-
0032529189
-
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
-
Paradis, S. & Ruvkun, G. Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes Dev. 12, 2488-2498 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 2488-2498
-
-
Paradis, S.1
Ruvkun, G.2
-
26
-
-
0031429098
-
nrb: Fine mapping, genomic structure, and exclusion as candidate genes of X-linked dystonia parkinsonism
-
nrb: fine mapping, genomic structure, and exclusion as candidate genes of X-linked dystonia parkinsonism. Hum. Genet. 100, 569-572 (1997).
-
(1997)
Hum. Genet.
, vol.100
, pp. 569-572
-
-
Peters, U.1
Haberhausen, G.2
Kostrzewa, M.3
Nolte, D.4
Müller, U.5
-
27
-
-
0030265564
-
Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase
-
Didichenko, S. A., Tilton, B., Hemmings, B. A., Ballmer-Hofer, K. & Thelen, M. Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase. Curr. Biol. 6, 1271-1278 (1996).
-
(1996)
Curr. Biol.
, vol.6
, pp. 1271-1278
-
-
Didichenko, S.A.1
Tilton, B.2
Hemmings, B.A.3
Ballmer-Hofer, K.4
Thelen, M.5
-
28
-
-
0025998840
-
Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates
-
Boyle, W. J., Van der Geer, P. & Hunter, T. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol. 201, 110-149 (1991).
-
(1991)
Methods Enzymol.
, vol.201
, pp. 110-149
-
-
Boyle, W.J.1
Van Der Geer, P.2
Hunter, T.3
-
29
-
-
0026059316
-
Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes
-
Luo, K. X., Hurley, T. R. & Sefton, B. M. Cyanogen bromide cleavage and proteolytic peptide mapping of proteins immobilized to membranes. Methods Enzymol. 201, 149-152 (1991).
-
(1991)
Methods Enzymol.
, vol.201
, pp. 149-152
-
-
Luo, K.X.1
Hurley, T.R.2
Sefton, B.M.3
-
30
-
-
0025361913
-
Transcriptional activation by TGF beta I is mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE)
-
De Groot, R. P. & Kruijer, W. Transcriptional activation by TGF beta I is mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE). Biochem. Biophys. Res. Commun. 168, 1074-1081 (1990).
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.168
, pp. 1074-1081
-
-
De Groot, R.P.1
Kruijer, W.2
|