The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3- kinase-dependent survival signaling cascade

Journal of Biological Chemistry

Volumn 275, Issue 26, 2000, Pages 20210-20216

  Rust, Christian ^a   Karnitz, Larry M ^a   Paya, Carlos V ^a   Moscat, Jorge ^b   Simari, Robert D ^a   Gores, Gregory J ^a,c  

^a MAYO CLINIC   (United States)

^b CSIC   (Spain)

^c MAYO CLINIC COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHENODEOXYCHOLIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; TAURINE DERIVATIVE; TAUROCHENODEOXYCHOLIC ACID;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURVIVAL; CHOLESTASIS; CYTOTOXICITY; HYDROPHOBICITY; LIVER CELL; LIVER INJURY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOVIRIDAE; ANIMALS; APOPTOSIS; BILE ACIDS AND SALTS; CELL SURVIVAL; DACTINOMYCIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLYCOCHENODEOXYCHOLIC ACID; IMMUNOBLOTTING; LUCIFERASES; NF-KAPPA B; ONCOGENE PROTEIN V-AKT; PLASMIDS; PROTEIN KINASE C; PROTEIN SYNTHESIS INHIBITORS; RATS; RETROVIRIDAE PROTEINS, ONCOGENIC; SIGNAL TRANSDUCTION; TAUROCHENODEOXYCHOLIC ACID; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0034733547     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M909992199     Document Type: Article

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