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1
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0030947095
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Programmed cell death in animal development
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Jacobson MD, Weil M, Raff MC. Programmed cell death in animal development. Cell. 88:1997;347-354.
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(1997)
Cell
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Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
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3
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0022497852
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Genetic control of programmed cell death in the nematode C. elegans
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Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell. 44:1986;817-829.
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(1986)
Cell
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Ellis, H.M.1
Horvitz, H.R.2
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4
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13344285339
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Identification and characterization of a new member of the TNF family that induces apoptosis
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Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, Sutherland GR, Smith TD, Rauch C, Smith CA, Goodwin RG. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity. 3:1995;673-682.
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(1995)
Immunity
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Wiley, S.R.1
Schooley, K.2
Smolak, P.J.3
Din, W.S.4
Huang, C.P.5
Nicholl, J.K.6
Sutherland, G.R.7
Smith, T.D.8
Rauch, C.9
Smith, C.A.10
Goodwin, R.G.11
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5
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17544367410
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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
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Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, Ashkenazi A. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem. 271:1996;12687-12690.
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(1996)
J Biol Chem
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Pitti, R.M.1
Marsters, S.A.2
Ruppert, S.3
Donahue, C.J.4
Moore, A.5
Ashkenazi, A.6
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6
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0027211704
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Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation
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Banner DW, D'Arcy A, Janes W, Gentz R, Schoenfeld H-J, Broger C, Loetscher H, Lesslauer W. Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: implications for TNF receptor activation. Cell. 73:1993;431-445.
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(1993)
Cell
, vol.73
, pp. 431-445
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Banner, D.W.1
D'Arcy, A.2
Janes, W.3
Gentz, R.4
Schoenfeld H-J5
Broger, C.6
Loetscher, H.7
Lesslauer, W.8
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7
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0030996297
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The receptor for the cytotoxic ligand TRAIL
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of special interest. This describes the screening of an expressed sequence tag database with the death domain of TNF-receptor-1 permitted the cloning of the first of four TNF-related apoptosis-inducing ligand (TRAIL) receptor, DR4/TRAIL-R1.
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Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, Dixit VM. The receptor for the cytotoxic ligand TRAIL. of special interest Science. 276:1997;111-113 This describes the screening of an expressed sequence tag database with the death domain of TNF-receptor-1 permitted the cloning of the first of four TNF-related apoptosis-inducing ligand (TRAIL) receptor, DR4/TRAIL-R1.
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(1997)
Science
, vol.276
, pp. 111-113
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Pan, G.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Gentz, R.4
Ebner, R.5
Ni, J.6
Dixit, V.M.7
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8
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0030762815
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An antagonist decoy receptor and a death domain-containing receptor for TRAIL
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of special interest. This provided bioinformatic identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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Pan G, Ni J, Wei Y-F, Yu GI, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. of special interest Science. 277:1997;815-818 This provided bioinformatic identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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(1997)
Science
, vol.277
, pp. 815-818
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Pan, G.1
Ni, J.2
Wei Y-F3
Yu, G.I.4
Gentz, R.5
Dixit, V.M.6
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9
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0030792712
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Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
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of special interest. This provided bioinformatic identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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Sheridan JP, Marsters SA, Pitti PM, Gurney A, Skubatch M, Baldwin D, Ramakrishnan L, Gray CL, Baker K, Wood WI, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. of special interest Science. 277:1997;818-821 This provided bioinformatic identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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(1997)
Science
, vol.277
, pp. 818-821
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Sheridan, J.P.1
Marsters, S.A.2
Pitti, P.M.3
Gurney, A.4
Skubatch, M.5
Baldwin, D.6
Ramakrishnan, L.7
Gray, C.L.8
Baker, K.9
Wood, W.I.10
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10
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0030880548
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TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
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of special interest. This provided biochemical identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. of special interest EMBO J. 16:1997;5386-5397 This provided biochemical identification of a second death-inducing TNF-related apoptosis-inducing ligand (TRAIL) receptor (DR5/TRAIL-R2) and increased the complexity of the TRAIL/TRAIL-receptor system.
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(1997)
EMBO J
, vol.16
, pp. 5386-5397
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Walczak, H.1
Degli-Esposti, M.A.2
Johnson, R.S.3
Smolak, P.J.4
Waugh, J.Y.5
Boiani, N.6
Timour, M.S.7
Gerhart, M.J.8
Schooley, K.A.9
Smith, C.A.10
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11
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0030869432
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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
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of special interest. As with [8] and [9], the ligand-binding domain of TNF-related apoptosis-inducing ligand (TRAIL)-R1 was used to identify a third, nonsignaling TRAIL-R (TRID/DcR1/TRAIL-R3), the existence of which possibly explains the differences in susceptibility between normal and tumor cells.
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Degli-Esposti MA, Smolak PJ, Walczak H, Waugh J, Huang C-P, DuBose RF, Goodwin RG, Smith CA. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. of special interest J Exp Med. 186:1997;1165-1170 As with [8] and [9], the ligand-binding domain of TNF-related apoptosis-inducing ligand (TRAIL)-R1 was used to identify a third, nonsignaling TRAIL-R (TRID/DcR1/TRAIL-R3), the existence of which possibly explains the differences in susceptibility between normal and tumor cells.
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(1997)
J Exp Med
, vol.186
, pp. 1165-1170
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Degli-Esposti, M.A.1
Smolak, P.J.2
Walczak, H.3
Waugh, J.4
Huang C-P5
Dubose, R.F.6
Goodwin, R.G.7
Smith, C.A.8
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12
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0031414749
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The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
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of special interest. Using the ligand-binding domain of TNF-related apoptosis-inducing ligand receptor 3 (TRAIL-R3), a fourth TRAIL-R (TRAIL-R4) was identified that lacked a complete death domain but could signal for activation of the transcription factor NF-κB. This suggested resistance to TRAIL-induced death could result from TRAIL-R4, via an antiapoptotic signal (see [14] and [15]), in addition to the 'decoy' TRAIL-R3.
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Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. of special interest Immunity. 7:1997;813-820 Using the ligand-binding domain of TNF-related apoptosis-inducing ligand receptor 3 (TRAIL-R3), a fourth TRAIL-R (TRAIL-R4) was identified that lacked a complete death domain but could signal for activation of the transcription factor NF-κB. This suggested resistance to TRAIL-induced death could result from TRAIL-R4, via an antiapoptotic signal (see [14] and [15]), in addition to the 'decoy' TRAIL-R3.
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(1997)
Immunity
, vol.7
, pp. 813-820
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Degli-Esposti, M.A.1
Dougall, W.C.2
Smolak, P.J.3
Waugh, J.Y.4
Smith, C.A.5
Goodwin, R.G.6
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13
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13144265771
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A novel receptor for Apo2L/TRAIL contains a truncated death domain
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Marsters SA, Sheridan JP, Pitti RM, Huang A, Skubatch M, Baldwin D, Yuan J, Gurney A, Goddard AD, Godowski P, Ashkenazi A. A novel receptor for Apo2L/TRAIL contains a truncated death domain. Curr Biol. 7:1997;1003-1006.
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(1997)
Curr Biol
, vol.7
, pp. 1003-1006
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Marsters, S.A.1
Sheridan, J.P.2
Pitti, R.M.3
Huang, A.4
Skubatch, M.5
Baldwin, D.6
Yuan, J.7
Gurney, A.8
Goddard, A.D.9
Godowski, P.10
Ashkenazi, A.11
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14
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0029976817
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An essential role for NF-κB in preventing TNF-α-induced cell death
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Beg AA, Baltimore D. An essential role for NF-κB in preventing TNF-α-induced cell death. Science. 274:1996;782-784.
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(1996)
Science
, vol.274
, pp. 782-784
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Beg, A.A.1
Baltimore, D.2
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15
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0029992609
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Suppression of TNF-α-induced apoptosis by NF-κB
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Van Antwerp DJ, Martin SJ, Kafri T, Green DR, Verma IM. Suppression of TNF-α-induced apoptosis by NF-κB. Science. 274:1996;787-789.
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(1996)
Science
, vol.274
, pp. 787-789
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Van Antwerp, D.J.1
Martin, S.J.2
Kafri, T.3
Green, D.R.4
Verma, I.M.5
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16
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0031406386
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Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway
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Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity. 7:1997;821-830.
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(1997)
Immunity
, vol.7
, pp. 821-830
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Chaudhary, P.M.1
Eby, M.2
Jasmin, A.3
Bookwalter, A.4
Murray, J.5
Hood, L.6
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17
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0031405585
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TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB
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Schneider P, Thome M, Burns K, Bodmer J-L, Hofmann K, Kataoka T, Holler N, Tschopp J. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB. Immunity. 7:1997;831-836.
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(1997)
Immunity
, vol.7
, pp. 831-836
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Schneider, P.1
Thome, M.2
Burns, K.3
Bodmer J-L4
Hofmann, K.5
Kataoka, T.6
Holler, N.7
Tschopp, J.8
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18
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0030254388
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Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family
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Wallach D, Boldin M, Goncharov T, Goltsev Y, Mett I, Malinin N, Adar R, Kovalenko A, Varfolomeev E. Exploring cell death mechanisms by analyzing signaling cascades of the TNF/NGF receptor family. Behring Inst Mitt. 97:1996;144-155.
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(1996)
Behring Inst Mitt
, vol.97
, pp. 144-155
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Wallach, D.1
Boldin, M.2
Goncharov, T.3
Goltsev, Y.4
Mett, I.5
Malinin, N.6
Adar, R.7
Kovalenko, A.8
Varfolomeev, E.9
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20
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0032530612
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Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells
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This is a demonstration that sensitivity/resistance of tumor cells to TNF-related apoptosis-inducing ligand (TRAIL) does not correlate with TRAIL-receptor-3 or TRAIL-receptor-4 mRNA expression, but instead correlates with intracellular concentrations of Fas-associated death-domain-like IL-1β-converting enzyme (FLICE)-like inhibitory protein of special interest
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Griffith TS, Chin WA, Jackson GC, Lynch DH, Kubin MZ. Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells. of special interest J Immunol. 161:1998; This is a demonstration that sensitivity/resistance of tumor cells to TNF-related apoptosis-inducing ligand (TRAIL) does not correlate with TRAIL-receptor-3 or TRAIL-receptor-4 mRNA expression, but instead correlates with intracellular concentrations of Fas-associated death-domain-like IL-1β-converting enzyme (FLICE)-like inhibitory protein.
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(1998)
J Immunol
, vol.161
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Griffith, T.S.1
Chin, W.A.2
Jackson, G.C.3
Lynch, D.H.4
Kubin, M.Z.5
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21
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0030934465
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Fas-associated death domain protein interleukin-1β-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- And p55-mediated death signaling
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Vincenz C, Dixit VM. Fas-associated death domain protein interleukin-1β-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling. J Biol Chem. 272:1997;6578-6583.
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(1997)
J Biol Chem
, vol.272
, pp. 6578-6583
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Vincenz, C.1
Dixit, V.M.2
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22
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0344053451
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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
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Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwick G, Alnemri ES. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc Natl Acad Sci USA. 93:1996;7464-7469.
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(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7464-7469
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Fernandes-Alnemri, T.1
Armstrong, R.C.2
Krebs, J.3
Srinivasula, S.M.4
Wang, L.5
Bullrich, F.6
Fritz, L.C.7
Trapani, J.A.8
Tomaselli, K.J.9
Litwick, G.10
Alnemri, E.S.11
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23
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0031037897
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The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
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Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science. 275:1997;1132-1136.
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(1997)
Science
, vol.275
, pp. 1132-1136
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Kluck, R.M.1
Bossy-Wetzel, E.2
Green, D.R.3
Newmeyer, D.D.4
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25
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0030800070
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Inhibition of death receptor signals by cellular FLIP
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of special interest. Regulation of death induction by members of the TNF receptor family was found to occur through the interaction of the caspase-8 homolog cFLIP with Fas-associated death domain and caspase-8.
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Irmler M, Thome M, Hahne M, Schneider P, Hofmann K, Steiner V, Bodmer J-L, Schroter M, Burns K, Mattmann C, et al. Inhibition of death receptor signals by cellular FLIP. of special interest Nature. 388:1997;190-195 Regulation of death induction by members of the TNF receptor family was found to occur through the interaction of the caspase-8 homolog cFLIP with Fas-associated death domain and caspase-8.
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(1997)
Nature
, vol.388
, pp. 190-195
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Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer J-L7
Schroter, M.8
Burns, K.9
Mattmann, C.10
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