메뉴 건너뛰기




Volumn 250, Issue 2, 2001, Pages 105-120

The dysmetabolic syndrome

Author keywords

Abdominal obesity; Dyslipidaemia; Hypertension; Insulin resistance; Thrifty genes; Type 2 diabetes

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; FATTY ACID BINDING PROTEIN; FURIN; GLYCOGEN SYNTHASE; GLYCOPROTEIN; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 2; LEPTIN; LEPTIN RECEPTOR; MELANOCORTIN RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROOPIOMELANOCORTIN; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; UNCOUPLING PROTEIN;

EID: 0034825009     PISSN: 09546820     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2796.2001.00864.x     Document Type: Review
Times cited : (194)

References (158)
  • 1
    • 0024160877 scopus 로고
    • Role of insulin resistance in human disease
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.1
  • 3
    • 0026021161 scopus 로고
    • Insulin resistance. A multifacet syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease
    • (1991) Diabetes Care , vol.14 , pp. 173-194
    • DeFronzo, R.1    Ferrannini, E.2
  • 10
    • 17344388503 scopus 로고    scopus 로고
    • Insulin sensitivity and acute insulin response in African-Americans, non-Hispanic whites and Hispanics with NIDDM: The insulin resistance atherosclerosis study
    • (1997) Diabetes , vol.46 , pp. 63-69
    • Haffner, S.1    Howard, G.2    Mayer, E.3
  • 11
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus, provisional report of a WHO consultation
    • (1998) Diabetic Med , vol.15 , pp. 539-553
    • Alberti, K.1    Zimmet, P.2    Consultation, W.3
  • 14
    • 0028091753 scopus 로고
    • Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus
    • (1994) J Clin Invest , vol.94 , pp. 1714-1721
    • Beck-Nielsen, H.1    Groop, L.2
  • 15
    • 0031026938 scopus 로고    scopus 로고
    • Non-insulin-dependent diabetes mellitus - A collision between thrifty genes and an affluent society
    • (1997) Ann Med , vol.29 , pp. 37-53
    • Groop, L.1    Tuomi, T.2
  • 29
    • 0027140992 scopus 로고
    • Insulin resistance is related to albuminuria in patients with type II (non-insulin-dependent) diabetes mellitus
    • (1993) Metabolism , vol.42 , pp. 1541-1545
    • Niskanen, L.1    Laakso, M.2
  • 37
    • 70349566593 scopus 로고
    • Diabetes mellitus: A 'thrifty' genotype rendered detrimental by progress?
    • (1962) Am J Hum Genet , vol.14 , pp. 352-362
    • Neel, V.1
  • 38
    • 0018355535 scopus 로고
    • Obesity genes: Beneficial effects in hetrozygous mice
    • (1979) Science , vol.203 , pp. 663-665
    • Coleman, D.1
  • 62
    • 0031455342 scopus 로고    scopus 로고
    • Linkage and association studies between the melanocortin receptor-4 and receptor-5 genes and obesity-related phenotypes in the Quebec family study
    • (1997) Mol Med , vol.3 , pp. 663-673
    • Chagnon, Y.1    Chen, W.2    Perusse, L.3
  • 65
    • 15644369364 scopus 로고    scopus 로고
    • Systematic mutation screening of the pro-opiomelanocortin gene: Identification of several genetic variants including three different insertions, one nonsense and two missense point mutations in probands of different weight extremes
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3737-3741
    • Hinney, A.1    Becker, I.2    Heibult, O.3
  • 78
    • 0029658675 scopus 로고    scopus 로고
    • The Trp64Arg mutation of the beta-3-adrenergic receptor gene has no effect on obesity phenotypes in the Quebec family study and Swedish Obese subjects cohort
    • (1996) J Clin Invest , vol.98 , pp. 2086-2093
    • Gagnon, J.1    Mauriege, P.2    Roy, S.3
  • 85
    • 0032589901 scopus 로고    scopus 로고
    • Polymorphism of the human beta-3-adrenoceptir gene forms a well-conserved haplotype that is associated with moderate obesity and altered receptor function
    • (1999) Diabetes , vol.48 , pp. 203-205
    • Hoffstedt, J.1    Poirier, O.2    Thörne, A.3
  • 88
    • 0030759095 scopus 로고    scopus 로고
    • The role of nonesterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: Results of the Paris Prospective Study
    • (1997) Diabetologia , vol.40 , pp. 1101-1106
    • Charles, M.1    Eschwege, E.2    Thibult, N.3
  • 96
    • 0028940934 scopus 로고
    • An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation and insulin resistance
    • (1995) J Clin Invest , vol.95 , pp. 1281-1287
    • Baier, L.1    Sacchettini, J.2    Knowler, W.3
  • 99
    • 0030838107 scopus 로고    scopus 로고
    • Association between Ala54Thr substitution of the fatty acid-binding protein 2 gene with insulin resistance and intra-abdominal fat thickness in Japanese men
    • (1997) Diabetologia , vol.40 , pp. 706-710
    • Yamada, K.1    Yuan, X.2    Ishiyama, S.3
  • 110
    • 0029843407 scopus 로고    scopus 로고
    • Additve effect of A-G (-3826) variant of the uncoupling protein gene and the Trp64Arg mutation of the beta-3-adrenergic receptor gene on weight gain in morbid obesity
    • (1996) Int J Obesity , vol.20 , pp. 1062-1066
    • Clement, K.1    Ruiz, J.2    Cassard-Doulcier, A.3
  • 115
  • 128
    • 0031595923 scopus 로고    scopus 로고
    • A Pro12Ala substitution in PPARgamma2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
    • (1998) Nature Genet , vol.20 , pp. 284-287
    • Deeb, S.1    Fajas, L.2    Nemoto, M.3
  • 132
    • 0033863689 scopus 로고    scopus 로고
    • Association between the human glycoprotein PC-1 gene and elevated glucose and insulin levels in a paired-sibling analysis
    • (2000) Diabetes , vol.49 , pp. 1601-1603
    • Gu, H.1    Almgren, P.2    Lindholm, E.3
  • 137
    • 0033755408 scopus 로고    scopus 로고
    • Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia
    • (2000) Diabetes , vol.49 , pp. 1880-1889
    • Kubota, N.1    Tobe, K.2    Terauchi, Y.3
  • 145
    • 0035149804 scopus 로고    scopus 로고
    • The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism
    • (2001) Diabetes , vol.50 , pp. 195-198
    • St-Onge, J.1    Joanisse, D.2    Simoneau, J.3
  • 147
    • 0033758721 scopus 로고    scopus 로고
    • The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. II. An autosomal genome scan for diabetes-related quantitative-trait loci
    • (2000) Am J Hum Genet , vol.67 , pp. 1186-1200
    • Watanabe, R.1    Ghosh, S.2    Langefeld, C.3
  • 150
    • 1842292786 scopus 로고    scopus 로고
    • Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on human homologous region 20q
    • (1997) J Clin Invest , vol.100 , pp. 1240-1247
    • Lembertas, A.1    Perusse, L.2    Chagnon, Y.3
  • 153
  • 154
    • 0030766446 scopus 로고    scopus 로고
    • A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene
    • (1997) Hum Mol Gen , vol.6 , pp. 1401-1408
    • Zouali, H.1    Hani, E.2    Philippi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.