Heritability of albumin excretion rate in families of patients with Type II diabetes

Diabetologia

Volumn 42, Issue 11, 1999, Pages 1359-1366

  Forsblom, C M ^b   Kanninen, T ^a   Lehtovirta, M ^b   Saloranta, C ^b   Groop, L C ^a  

^a LUND UNIVERSITY   (Sweden)

^b NONE

Author keywords

Albumin excretion rate; Diabetic nephropathy; Heritability; Microalbuminuria; Type II (non insulin dependent) diabetes mellitus

Indexed keywords

ALBUMIN; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; TRIACYLGLYCEROL;

ADULT; AGED; ARTICLE; DIABETIC NEPHROPATHY; FEMALE; FINLAND; GENETIC PREDISPOSITION; HERITABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN URINE LEVEL; URINARY EXCRETION;

ADULT; AGED; ALBUMINURIA; BLOOD PRESSURE; DIABETES MELLITUS, TYPE 2; DIASTOLE; FEMALE; HUMANS; MALE; MIDDLE AGED; REFERENCE VALUES; REGRESSION ANALYSIS; SYSTOLE;

EID: 0003649818     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051450     Document Type: Article

References (47)

1. 1. Kofoed-Enevoldsen A, Borch-Johnsen K, Kreiner S, Nerup J, Deckert T (1987) Declining incidence of persistent proteinuria in type 1 (insulin-dependent) diabetic patients in Denmark. Diabetes 36: 205-209
2. 2. Ballard DJ, Humphrey LL, Melton JM III et al. (1988) Epidemiology of persistent proteinuria in Type II diabetes mellitus. Population-based study in Rochester, Minnesota. Diabetes 37: 405-412
3. 3. Kunzelman CL, Knowler WC, Pettitt DJ, Bennett PH (1989) Incidence of proteinuria in type 2 diabetes mellitus in the Pima Indians. Kidney Int 35: 681-687
4. 4. Seaquist ER, Goetz FC, Rich S, Barbosa J (1989) Familial clustering of diabetic kidney disease. Evidence for genetic susceptibility to diabetic nephropathy. N Engl J Med 320: 1161-1164
5. 5. The Diabetes Control and Complications Trial Research Group (1997) Clustering of long-term complications in families with diabetes in the Diabetes Control and Complications Trial. Diabetes 46: 1829-1839
6. 6. Pettitt DJ, Saad MF, Bennett PH, Nelson RG, Knowler WC (1990) Familial predisposition to renal disease in two generations of Pima Indians with Type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 33: 438-443
7. 7. Viberti GC, Hill RD, Jarrett RJ, Argyropoulos A, Mahmud U, Keen H (1982) Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus. Lancet 1: 1430-1432
8. 8. Parving H-H, Oxenböll B, Svendsen PA, Christiansen JS, Andersen AR (1982) Early detection of patients at risk of developing diabetic nephropathy. A longitudinal study of urinary albumin excretion. Acta Endocrinol 100: 550-555
9. 9. Mogensen CE, Christensen CK (1984) Predicting diabetic nephropathy in insulin-dependent patients. N Engl J Med 311: 89-93
10. 10. Mogensen CE (1984) Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N Engl J Med 310: 356-360
11. 11. Mattock MB, Keen H, Viberti GC et al. (1988) Coronary heart disease and urinary albumin excretion rate in type 2 (non-insulin dependent) diabetic patients. Diabetologia 31: 82-87
12. 12. Falconer DS (1981) Introduction to quantitative genetics. 2nd edn. Longman Scientific & Technical, Harlow, Essex
13. 13. Gall M-A, Rossing P, Skött P et al. (1991) Prevalence of micro-and macroalbuminuria, arterial hypertension, retinopathy and large vessel disease in European Type 2 (non-insulin-dependent) diabetic patients. Diabetologia 34: 655-661
14. 14. Groop L, Forsblom C, Lehtovirta M et al. (1996) Metabolic consequences of a family history of NIDDM (The Botnia Study). Evidence for sex-specific parental effects. Diabetes 45: 1585-1593
15. 15. Bland JM, Altman DG (1986) Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1: 307-310
16. 16. MacLeod JM, Lutale J, Marshall SM (1995) Albumin excretion and vascular deaths in NIDDM. Diabetologia 38: 610-616
17. 17. World Health Organization Study Group on Diabetes mellitus (1985) Technical report series No 727, WHO Geneva
18. 18. World Health Organization (1987) Measuring obesity -classification and description of anthropometric data. Report on a WHO Consultation on the Epidemiology of Obesity. WHO, Warsaw, pp 2-7
19. 19. Mitchell BD, Kammerer CM, Blangero J et al. (1996) Genetic and environmental contributions to cardiovascular risk factors in Mexican Americans. The San Antonio Family Heart Study. Circulation 94: 2159-2170
20. 20. Fagard R, Brguljan J, Staessen J et al. (1995) Heritability of conventional and ambulatory blood pressures. A study in twins. Hypertension 26: 919-924
21. 21. Khoury MJ, Beaty TH, Liang K-Y (1988) Can familial aggregation of disease be explained by familial aggregation of environmental risk factors. Am J Epidemiol 127: 674-683
22. 22. Groop L, Mäkipernaa A, Stenman S, DeFronzo RA, Teppo A-M (1990) Urinary excretion of kappa light chains in patients with diabetes mellitus. Kidney Int 37: 1120-1125
23. 23. Gruden G, Cavallo-Perin P, Olivetti C et al. (1995) Albumin excretion rate levels in non-diabetic offspring of NIDDM patients with and without nephropathy. Diabetologia 38: 1218-1222
24. 24. Strojek K, Grzeszczak W, Morawin E et al. (1997) Nephropathy of Type II diabetes: evidence for hereditary factors? Kidney Int 51: 1602-1607
25. 25. Lökkegaard N, Haupter I, Kristensen TB (1992) Microalbuminuria in obesity. Scand J Urol Nephrol 26: 275-278
26. 26. Basdevant A, Cassuto D, Gibault T, Raison J, Guy-Grand B (1994) Microalbuminuria and body fat distribution in obese subjects. Int J Obes 18: 806-811
27. 27. Faronato PP, Maioli M, Tonolo G et al. (1997) Clustering of albumin excretion rate abnormalities in Caucasian patients with NIDDM. Diabetologia 40: 816-823
28. 28. Knowler WC, Pettitt DJ, Saad MF, Bennett PH (1990) Diabetes mellitus in the Pima Indians: Incidence, risk factors and pathogenesis. Diabetes/Metab Rev 6: 1-27
29. 29. McCance DR, Hanson RL, Pettitt DJ et al. (1995) Diabetic nephropathy: a risk factor for diabetes mellitus in offspring. Diabetologia 38: 221-226
30. 30. Haffner SM, Gonzales C, Valdez RA et al. (1993) Is microalbuminuria part of the prediabetic state? The Mexico City Diabetes Study. Diabetologia 36: 1002-1006
31. 31. Mykkänen L, Zaccaro DJ, Wagenknecht LE, Robbins DC, Gabriel M, Haffner SM (1998) Microalbuminuria is associated with insulin resistance in nondiabetic subjects. Diabetes 47: 793-800
32. 32. Groop L, Ekstrand A, Forsblom C et al. (1993) Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus. Diabetologia 36: 642-647
33. 33. Forsblom CM, Eriksson JG, Ekstrand AV, Teppo A-M, Taskinen M-R, Groop LC (1995) Insulin resistance and abnormal albumin excretion in non-diabetic first-degree relatives of patients with NIDDM. Diabetologia 38: 363-369
34. 34. Quinn M, Angelico MC, Warram JH, Krolewski AS (1996) Familial factors determine the development of diabetic nephropathy in patients with IDDM. Diabetologia 39: 940-945
35. 35. Deckert T, Feldt-Rasmussen B, Borch-Johnsen K, Jensen T, Kofoed-Enevoldsen A (1989) Albuminuria reflects widespread vascular damage. The Steno hypothesis. Diabetologia 32: 219-226
36. 36. Stehouwer CDA, Nauta JJP, Zeldenrust GC, Hackeng WHL, Donker AJM, den Ottolander GJH (1992) Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin dependent diabetes mellitus. Lancet 340: 319-323
37. 37. Chen JW, Gall M-A, Deckert M, Jensen JS, Parving H-H (1995) Increased concentration of von Willebrand factor in non-insulin dependent diabetic patients with and without diabetic nephropathy. BMJ 311: 1405-1406
38. 38. Fioretto P, Stehouwer CDA, Mauer M et al. (1998) Heterogeneous nature of microalbuminuria in NIDDM: studies of endothelial function and renal structure. Diabetologia 41: 233-236
39. 39. Mykkänen L, Haffner SM, Kuusisto J, Pyörälä K, Laakso M (1994) Microalbuminuria precedes the development of NIDDM. Diabetes 43: 552-557
40. 40. Gall M-A, Borch-Johnsen K, Hougaard P, Nielsen FS, Parving H-H (1995) Albuminuria and poor glycemic control predict mortality in NIDDM. Diabetes 44: 1303-1309
41. 41. Forsblom C, Sane T, Groop P-H et al. (1998) Risk factors for mortality in Type II (non-insulin-dependent) diabetes: evidence of a role for neuropathy and a protective effect of HLA-DR4. Diabetologia 41: 1253-1262
42. 42. Doria A, Warram JH, Krolewski AS (1994) Genetic predisposition to diabetic nephropathy. Evidence for a role of the angiotensin I-converting enzyme gene. Diabetes 43: 690-695
43. 43. Fogarty DG, Harron JC, Hughes AE, Nevin NC, Doherty CC, Maxwell AP (1996) A molecular variant of angiotensinogen is associated with diabetic nephropathy in IDDM. Diabetes 45: 1204-1208
44. 44. Doria A, Onuma T, Warram JH, Krolewski AS (1997) Synergistic effect of angiotensin II type 1 receptor genotype and poor glycaemic control on risk of nephropathy in IDDM. Diabetologia 40: 1293-1299
45. 45. Heesom AE, Hibberd ML, Millward A, Demaine AG (1997) Polymorphism in the 5'-end of the aldose reductase gene is strongly associated with the development of diabetic nephropathy in Type I diabetes. Diabetes 46: 287-291
46. 46. Hansen PM, Chowdhury T, Deckert T, Hellgren A, Bain SC, Pociot F (1997) Genetic variation of the heparan sulfate proteoglycan gene (Perlecan gene). Association with urinary albumin excretion in IDDM patients. Diabetes 46: 1658-1659
47. 47. Fujisawa T, Ikegami H, Kawaguchi Y et al. (1998) Metaanalysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy. Diabetologia 41: 47-53