-
1
-
-
0032695482
-
Annual deaths attributable to obesity in the United States
-
Allison, D.B., Fontaine, K.R., Manson, J.E., Steven, J., and Vanltallie, T.B. 1999. Annual deaths attributable to obesity in the United States. JAMA. 282:1530-1538.
-
(1999)
JAMA
, vol.282
, pp. 1530-1538
-
-
Allison, D.B.1
Fontaine, K.R.2
Manson, J.E.3
Steven, J.4
Vanltallie, T.B.5
-
2
-
-
0032742418
-
The disease burden associated with overweight and obesity
-
Must, A., et al. 1999. The disease burden associated with overweight and obesity. JAMA. 282:1523-1529.
-
(1999)
JAMA
, vol.282
, pp. 1523-1529
-
-
Must, A.1
-
3
-
-
0004318660
-
-
World Health Organization. Geneva, Switzerland. Report no. WHO/NUT/NCD/98-1. 276 pp.
-
1998. Obesity: preventing and managing the global epidemic. World Health Organization. Geneva, Switzerland. Report no. WHO/NUT/NCD/98-1. 276 pp.
-
(1998)
Obesity: Preventing and Managing the Global Epidemic
-
-
-
4
-
-
0032697493
-
The spread of the obesity epidemic in the United States, 1991-1998
-
Mokdad, A.H., et al. 1999. The spread of the obesity epidemic in the United States, 1991-1998. JAMA. 282:1519-1522.
-
(1999)
JAMA
, vol.282
, pp. 1519-1522
-
-
Mokdad, A.H.1
-
5
-
-
0032577309
-
The search for human obesity genes
-
Comuzzie, A.G., and Allison, D.H. 1998. The search for human obesity genes. Science. 280:1374-1377.
-
(1998)
Science
, vol.280
, pp. 1374-1377
-
-
Comuzzie, A.G.1
Allison, D.H.2
-
6
-
-
0032577404
-
Environmental contributions to the obesity epidemic
-
Hill, J.O., and Peters, J.C. 1998. Environmental contributions to the obesity epidemic. Science. 280:1371-1374.
-
(1998)
Science
, vol.280
, pp. 1371-1374
-
-
Hill, J.O.1
Peters, J.C.2
-
7
-
-
0030878110
-
Congenital leptin deficiency is associated with severe early-onset obesity in humans
-
Montague, C.T., et al. 1997. Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature. 387:903-908.
-
(1997)
Nature
, vol.387
, pp. 903-908
-
-
Montague, C.T.1
-
8
-
-
0032014836
-
A leptin missense mutation associated with hypogonadism and morbid obesity
-
Strobel, A., Issad, T., Camoin, L., Ozata, M., and Strosberg, A.D. 1998. A leptin missense mutation associated with hypogonadism and morbid obesity. Nat. Genet. 18:213-215.
-
(1998)
Nat. Genet.
, vol.18
, pp. 213-215
-
-
Strobel, A.1
Issad, T.2
Camoin, L.3
Ozata, M.4
Strosberg, A.D.5
-
9
-
-
0344450708
-
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
-
Clement, K., et al. 1998. A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction. Nature. 392:398-401.
-
(1998)
Nature
, vol.392
, pp. 398-401
-
-
Clement, K.1
-
10
-
-
0031838353
-
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
-
Krude, H., et al. 1998. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat. Genet. 19:155-157.
-
(1998)
Nat. Genet.
, vol.19
, pp. 155-157
-
-
Krude, H.1
-
11
-
-
0030949271
-
Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene
-
Jackson, R.S., et al. 1997. Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene. Nat. Genet. 16:303-306.
-
(1997)
Nat. Genet.
, vol.16
, pp. 303-306
-
-
Jackson, R.S.1
-
12
-
-
0031662163
-
A frameshift mutation in human MC4R is associated with a dominant form of obesity
-
Vaisse, C., Clement, K., Guy-Grand, B., and Froguel, P. 1998. A frameshift mutation in human MC4R is associated with a dominant form of obesity. Nat. Genet. 20:113-114.
-
(1998)
Nat. Genet.
, vol.20
, pp. 113-114
-
-
Vaisse, C.1
Clement, K.2
Guy-Grand, B.3
Froguel, P.4
-
13
-
-
0031668219
-
A frameshift mutation in MC4R associated with dominantly inherited human obesity
-
Yeo, G.S., et al. 1998. A frameshift mutation in MC4R associated with dominantly inherited human obesity. Nat. Genet. 20:111-112.
-
(1998)
Nat. Genet.
, vol.20
, pp. 111-112
-
-
Yeo, G.S.1
-
14
-
-
0033343736
-
Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans
-
Hinney, A., et al. 1999. Several mutations in the melanocortin-4 receptor gene including a nonsense and a frameshift mutation associated with dominantly inherited obesity in humans. J. Clin. Endocrinol. Metab. 84:1483-1486.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1483-1486
-
-
Hinney, A.1
-
15
-
-
0033010326
-
Identification and functional analysis of novel human melanocortin-4 receptor variants
-
Gu, W., et al. 1999. Identification and functional analysis of novel human melanocortin-4 receptor variants. Diabetes. 48:635-639.
-
(1999)
Diabetes
, vol.48
, pp. 635-639
-
-
Gu, W.1
-
16
-
-
0027227288
-
Molecular cloning, expression, and gene localization of a fourth melanocortin receptor
-
Gantz, I., et al. 1993. Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J. Biol. Chem. 268:15174-15179.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15174-15179
-
-
Gantz, I.1
-
17
-
-
0031687052
-
Assignment of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping
-
Sundaramurthy, D., Campbell, D.A., Leek, J.P., Markham, A.F., and Pieri, L.F. 1998. Assignment of the melanocortin 4 receptor (MC4R) gene to human chromosome band 18q22 by in situ hybridisation and radiation hybrid mapping. Cytogenet. Cell Genet. 82:97-98.
-
(1998)
Cytogenet. Cell Genet.
, vol.82
, pp. 97-98
-
-
Sundaramurthy, D.1
Campbell, D.A.2
Leek, J.P.3
Markham, A.F.4
Pieri, L.F.5
-
18
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan, W., Boston, B.A., Kesterson, R.A., Hruby, V.J., and Cone, R.D. 1997. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature. 385:165-168.
-
(1997)
Nature
, vol.385
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
19
-
-
0028892429
-
Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: The subtilisin-like proprotein convertases
-
Rouille, Y., et al. 1995. Proteolytic processing mechanisms in the biosynthesis of neuroendocrine peptides: the subtilisin-like proprotein convertases. Front. Neuroendocrinol. 16:322-361.
-
(1995)
Front. Neuroendocrinol.
, vol.16
, pp. 322-361
-
-
Rouille, Y.1
-
20
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann, M.M., et al. 1997. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science. 278:135-138.
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
-
21
-
-
0031280002
-
Overexpression of Agrt leads to obesity in transgenic mice
-
Graham, M., Shutter, J.R., Sarmiento, U., Sarosi, I., and Stark, K.L. 1997. Overexpression of Agrt leads to obesity in transgenic mice. Nat. Genet. 17:273-274.
-
(1997)
Nat. Genet.
, vol.17
, pp. 273-274
-
-
Graham, M.1
Shutter, J.R.2
Sarmiento, U.3
Sarosi, I.4
Stark, K.L.5
-
22
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D., et al. 1997. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell. 88:131-141.
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
-
23
-
-
0030949624
-
Association of poorly controlled diabetes with low serum leptin in morbid obesity
-
Clément, K., et al. 1997. Association of poorly controlled diabetes with low serum leptin in morbid obesity. Int. J. Obes. 21:556-561.
-
(1997)
Int. J. Obes.
, vol.21
, pp. 556-561
-
-
Clément, K.1
-
24
-
-
0021989139
-
The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger
-
Stunkard, A.J., and Messick, S. 1985. The three-factor eating questionnaire to measure dietary restraint, disinhibition and hunger. J. Psycbosom. Res. 29:71-83.
-
(1985)
J. Psycbosom. Res.
, vol.29
, pp. 71-83
-
-
Stunkard, A.J.1
Messick, S.2
-
25
-
-
0020417197
-
A short questionnaire for the measurement of habitual physical activity in epidemiological studies
-
Baecke, J.A., Burema, J., and Frijters, J.E. 1982. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am. J. Clin. Nutr. 36:936-942.
-
(1982)
Am. J. Clin. Nutr.
, vol.36
, pp. 936-942
-
-
Baecke, J.A.1
Burema, J.2
Frijters, J.E.3
-
26
-
-
0032145872
-
A primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers in a general population: The SU-VI-MAX study-design, methods, and participants characteristics
-
Hercberg, S., et al. 1998. A primary prevention trial using nutritional doses of antioxidant vitamins and minerals in cardiovascular diseases and cancers in a general population: the SU-VI-MAX study-design, methods, and participants characteristics. Control. Clin. Trials. 19:336-351.
-
(1998)
Control. Clin. Trials
, vol.19
, pp. 336-351
-
-
Hercberg, S.1
-
27
-
-
0032230291
-
A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor
-
Lu, D., Vage, D.I., and Cone, R.D. 1998. A ligand-mimetic model for constitutive activation of the melanocortin-1 receptor. Mol. Endocrinol 12:592-604.
-
(1998)
Mol. Endocrinol
, vol.12
, pp. 592-604
-
-
Lu, D.1
Vage, D.I.2
Cone, R.D.3
-
28
-
-
0027240588
-
Differencial signal transduction by five splice variants of the PACAP receptor
-
Spengler, D., et al. 1993. Differencial signal transduction by five splice variants of the PACAP receptor. Nature. 365:170-175.
-
(1993)
Nature
, vol.365
, pp. 170-175
-
-
Spengler, D.1
-
29
-
-
17344371519
-
A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10
-
Hager, J., et al. 1998. A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10. Nat. Genet. 20:304-308.
-
(1998)
Nat. Genet.
, vol.20
, pp. 304-308
-
-
Hager, J.1
-
30
-
-
0031785614
-
Identification and molecular characterization of a small 11q23.3 de novo duplication in a patient with Rett syndrome manifestations
-
Delobel, B., et al. 1998. Identification and molecular characterization of a small 11q23.3 de novo duplication in a patient with Rett syndrome manifestations. Am. J. Med. Genet. 80:273-280.
-
(1998)
Am. J. Med. Genet.
, vol.80
, pp. 273-280
-
-
Delobel, B.1
-
31
-
-
0025286294
-
Human placental protein 14 gene: Sequence and characterization of a short duplication
-
Vaisse, C., Atger, M., Potier, B., and Milgrom, E. 1990. Human placental protein 14 gene: sequence and characterization of a short duplication. DNA Cell Biol. 9:401-413.
-
(1990)
DNA Cell Biol.
, vol.9
, pp. 401-413
-
-
Vaisse, C.1
Atger, M.2
Potier, B.3
Milgrom, E.4
-
32
-
-
0027435938
-
The rapid detection of unknown mutations in nucleic acids
-
Grompe, M. 1993. The rapid detection of unknown mutations in nucleic acids. Nat. Genet. 5:111-117.
-
(1993)
Nat. Genet.
, vol.5
, pp. 111-117
-
-
Grompe, M.1
-
33
-
-
0030740803
-
Molecular screening of the human melanocortin-4 receptor gene: Identification of a missense variant showing no association with obesity, plasma glucose, or insulin
-
Gotoda, T., Scott, J., and Aitman, T.J. 1997. Molecular screening of the human melanocortin-4 receptor gene: identification of a missense variant showing no association with obesity, plasma glucose, or insulin. Diabetologia. 40:976-979.
-
(1997)
Diabetologia
, vol.40
, pp. 976-979
-
-
Gotoda, T.1
Scott, J.2
Aitman, T.J.3
-
34
-
-
0025765272
-
Body Mass Index variations: Centiles from birth to 87 years
-
Rolland-Cachera, M.F., et al. 1991. Body Mass Index variations: centiles from birth to 87 years. Eur. J. Clin. Nutr. 45:33-21.
-
(1991)
Eur. J. Clin. Nutr.
, vol.45
, pp. 33-121
-
-
Rolland-Cachera, M.F.1
-
35
-
-
0039531811
-
Deletions of the N-terminal regions of the human melanocortin receptors
-
Schioth, H.B., Petersson, S., Muceniece, R., Szardenings, M., and Wikberg, J.E. 1997. Deletions of the N-terminal regions of the human melanocortin receptors. FEBS Lett. 410:223-228.
-
(1997)
FEBS Lett.
, vol.410
, pp. 223-228
-
-
Schioth, H.B.1
Petersson, S.2
Muceniece, R.3
Szardenings, M.4
Wikberg, J.E.5
-
36
-
-
0003423779
-
-
Humana Press. Totowa, New Jersey, USA. 324 pp.
-
Spiegel, A.M. 1998. G proteins, receptors, and disease. Humana Press. Totowa, New Jersey, USA. 324 pp.
-
(1998)
G Proteins, Receptors, and Disease
-
-
Spiegel, A.M.1
-
37
-
-
0032585961
-
Hiplosufficiency of the melanocortin-4 receptor gene in individuals with deletions of 18q
-
Cody, J.D., et al. 1999. Hiplosufficiency of the melanocortin-4 receptor gene in individuals with deletions of 18q. Hum. Genet. 105:424-427.
-
(1999)
Hum. Genet.
, vol.105
, pp. 424-427
-
-
Cody, J.D.1
|