The expression of TNFα by human muscle: Relationship to insulin resistance

Journal of Clinical Investigation

Volumn 97, Issue 4, 1996, Pages 1111-1116

  Saghizadeh, Mehrnoosh ^a   Ong, John M ^a   Garvey, W Timothy ^b   Henry, Robert R ^c   Kern, Philip A ^d,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

insulin resistance; non insulin dependent diabetes mellitus; obesity; quantitative reverse transcriptase polymerase chain reaction (RT PCR); tumor necrosis factor

Indexed keywords

GLUCOSE; INSULIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GLUCOSE TRANSPORT SYSTEM; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSTIMULATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MUSCLE METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; QUANTITATIVE DIAGNOSIS; RAT; VASTUS LATERALIS MUSCLE;

EID: 0030028606     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118504     Document Type: Article

References (22)

1. Sims, E.A.H. 1976. Experimental obesity, dietary induced thermogenesis and their clinical implications. Clin. Endocrinol. Metab. 5:377-395.
2. Bouchard, C, A. Tremblay. J.-P. Després, A Nadeau. P.J. Lupien, G. Thenault, J. Dussault. S. Moorjani. S. Pinault, and G. Fournier 1990. The response to long-term overfeeding in identical twins. N. Engl. J. Med. 322:1477-1482
3. Hotamisligil. G S., N S. Shargill, and B.M Spiegelmnan. 1993. Adipose expression of tumor necrosis factor-a. Direct role in obesity-linked insulin resistance. Science (Wash. DC). 259:87-91
4. Hotamisligil, G.S.. and B.M. Spiegelman. 1994. Tumor necrosis factor a: a key component of the obesity-diabetes link. [Review] Diabetes. 43:1271-1278.
5. Hotamisligil. G.S., P. Arner. J.F. Caro, R.L. Atkinson, and B.M. Spiegelman. 1995. Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J. Clin. Invest. 95:2409-2415.
6. Kern, P A., M. Saghizadeh. J.M. Ong, R.J. Bosch. R. Deem, and R.B. Simsolo. 1995. The expression of tumor necrosis factor in human adipose tissue Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J. Clin. Invest. 95:2111-2119.
7. Hotamisligil, G.S.. D.L Murray, L.N. Choy. and B.M. Spiegelman. 1994. Tumor necrosis factor a inhibits signaling from the insulin receptor. Proc. Natl. Acad. Sci. USA 91:4854-4858
8. Hotamisligil, O.S., A Budavari, D Murray, and B.M Spiegelman. 1994. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha. J. Clin invest. 94:1543-1549.
9. DeFronzo, R A, E. Jacot. E. Jequier, E. Maeder, J. Wahren, and J.P. Felber 1981. The effect of insulin on the disposal of intravenous glucose Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes. 30:1000-1007.
10. Hotamisligil, G.S., A. Budavari, D. Murray, and B M. Spiegelman. 1994. Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-a. J. Clin Invest. 94:1543-1549.
11. DeFronzo, R A., J.D Tobin. and R. Andres. 1979. Glucose clamp technique: a method for quantifying insulin secretion and resistance Am J. Physiol. 237:E214-E223.
12. Garvey, W T , J.M. Olefsky, J Griffin, R.F Hamman, and O.G. Kolterman 1985 The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes. 34-222-234.
13. Henry, R R., L. Abrams. S. Nikalina. and T.P. Ciaraldi. 1995. Insulin action and glucose metabolism in nondiabetic control and NIDDM subjects. Comparison using human skeletal muscle cell cultures. Diabetes 44:936-946.
14. Webster. C., G K. Pavlath. D.R. Parks. F.S. Walsh, and H.M. Blau. 1988. Isolation of human myoblasts with a fluorescence-activated cell sorter. Exp. Cell Res. 17:252-265.
15. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156-159.
16. Andus, T., S.R. Targan, R. Deem, and H. Toyoda. 1993. Measurement of tumor necrosis factor alpha mRNA in small numbers of cells by quantitative polymerase chain reaction. Regional Immunol. 5:11-17.
17. Grunfeld, C., and K.R. Feingold. 1992. Seminars in medicine of the Beth Israel Hospital, Boston: Metabolic disturbances and wasting in the acquired immunodeficiency syndrome. N. Engl. J. Med 327:329-337.
18. Fried, S.K., and R. Zechner. 1989. Cachectin/tumor necrosis factor decreases human adipose tissue lipoprotein lipase mRNA levels, synthesis, and activity. J. Lipid Res. 30:1917-1923.
19. . Grunfeld, C, R. Gulli, A.H. Moser, L.A. Gavin, and K.R. Feingold. 1989. Effect of tumor necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat. J. Lipid Res. 30:579-585.
20. Stephens. J.M., and P.H. Pekala. 1991. Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-α. J. Biol. Chem. 266:21839-21845.
21. Patton, J.S., H.M. Shepard, H. Wilking, G. Lewis, B.B. Aggarwal. T.E. Eessalu, L.A. Gavin, and C. Grunfeld. 1986. Interferons and tumor necrosis factors have similar catabolic effects on 3T3-L1 cells. Proc. Natl. Acad Sci. USA. 83:8313-8317.
22. Socher, S.H., D. Martinez, J.B. Craig, J.G Kuhn, and A. Oliff. 1988 Tumor necrosis factor not detectable in patients with clinical cancer cachexia. J. Natl. Cancer Inst. 80:595-598.