-
1
-
-
0025784539
-
Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6
-
1. Yonish-Rouach E, Resnitzky D, Lotem J, Sachs L, Kimchi A, Oren M (1991) Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature 352:345-347
-
(1991)
Nature
, vol.352
, pp. 345-347
-
-
Yonish-Rouach, E.1
Resnitzky, D.2
Lotem, J.3
Sachs, L.4
Kimchi, A.5
Oren, M.6
-
2
-
-
0028456527
-
Relationship of p53 to the control of apoptotic cell death
-
2. Oren M (1994) Relationship of p53 to the control of apoptotic cell death. Semin Cancer Biol 5:221-227
-
(1994)
Semin Cancer Biol
, vol.5
, pp. 221-227
-
-
Oren, M.1
-
3
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
3. Lowe SW, Schmitt EM, Smith SW, Osborne BA, Jacks T (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature 362:847-849
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
4
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
4. Clarke AR, Purdie CA, Harrison DJ, Morris RG, Bird CC, Hooper ML, Wyllie AH (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature 362:849-852
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
5
-
-
0028301094
-
p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation
-
5. Clarke AR, Gledhill S, Hooper ML, Bird CC, Wyllie AH (1994) p53 dependence of early apoptotic and proliferative responses within the mouse intestinal epithelium following gamma-irradiation. Oncogene 9:1767-1773
-
(1994)
Oncogene
, vol.9
, pp. 1767-1773
-
-
Clarke, A.R.1
Gledhill, S.2
Hooper, M.L.3
Bird, C.C.4
Wyllie, A.H.5
-
6
-
-
0029980043
-
p53 in growth control and neoplasia
-
6. Gottlieb TM, Oren M (1996) p53 in growth control and neoplasia. Biochim Biophys Acta 1287:77-102
-
(1996)
Biochim Biophys Acta
, vol.1287
, pp. 77-102
-
-
Gottlieb, T.M.1
Oren, M.2
-
7
-
-
0029972806
-
p53: Puzzle and paradigm
-
7. Ko LJ, Prives C (1996) p53: puzzle and paradigm. Genes Dev 10:1054-1072
-
(1996)
Genes Dev
, vol.10
, pp. 1054-1072
-
-
Ko, L.J.1
Prives, C.2
-
8
-
-
0031051042
-
p53: From inductive signal to cellular effect
-
8. Hansen R, Oren M (1997) p53: from inductive signal to cellular effect. Curr Opin Genet Dev 7:46-51
-
(1997)
Curr Opin Genet Dev
, vol.7
, pp. 46-51
-
-
Hansen, R.1
Oren, M.2
-
9
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
9. Levine AJ (1997) p53, the cellular gatekeeper for growth and division. Cell 88:323-331
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
10
-
-
0027251720
-
Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B
-
10. Debbas M, White E (1993) Wild-type p53 mediates apoptosis by E1A, which is inhibited by E1B. Genes Dev 7:546-554
-
(1993)
Genes Dev
, vol.7
, pp. 546-554
-
-
Debbas, M.1
White, E.2
-
11
-
-
0028222124
-
p53 and E2F-1 cooperate to mediate apoptosis
-
11. Wu X, Levine AJ (1994) p53 and E2F-1 cooperate to mediate apoptosis. Proc Natl Acad Sci USA 91:3602-3606
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3602-3606
-
-
Wu, X.1
Levine, A.J.2
-
12
-
-
0027947383
-
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis
-
12. Qin XQ, Livingston DM, Kaelin WJ, Adams PD (1994) Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci USA 91:10918-10922
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 10918-10922
-
-
Qin, X.Q.1
Livingston, D.M.2
Kaelin, W.J.3
Adams, P.D.4
-
14
-
-
0028171968
-
Mediation of c-Myc-induced apoptosis by p53
-
14. Hermeking H, Eick D (1994) Mediation of c-Myc-induced apoptosis by p53. Science 265:2091-2093
-
(1994)
Science
, vol.265
, pp. 2091-2093
-
-
Hermeking, H.1
Eick, D.2
-
15
-
-
0030025773
-
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors
-
15. Graeber TG, Osmanian C, Jacks T, Housman DE, Koch CJ, Lowe SW, Giaccia AJ (1996) Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumors. Nature 379:88-91
-
(1996)
Nature
, vol.379
, pp. 88-91
-
-
Graeber, T.G.1
Osmanian, C.2
Jacks, T.3
Housman, D.E.4
Koch, C.J.5
Lowe, S.W.6
Giaccia, A.J.7
-
16
-
-
0029964158
-
A reversible G0/G1 arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
-
16. Linke SP, Clarkin KC, Leonardo AD, Tsou A, Wahl GM (1996) A reversible G0/G1 arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes Dev 10:934-947
-
(1996)
Genes Dev
, vol.10
, pp. 934-947
-
-
Linke, S.P.1
Clarkin, K.C.2
Leonardo, A.D.3
Tsou, A.4
Wahl, G.M.5
-
17
-
-
0032510136
-
Involvement of p85 in p53-dependent apoptotic response to oxidative stress
-
17. Yin Y, Terauchi Y, Solomon GG, Aizawa S, Rangarajan PN, Yazaki Y, Kadowaki T, Barrett JC (1998) Involvement of p85 in p53-dependent apoptotic response to oxidative stress. Nature 391:707-710
-
(1998)
Nature
, vol.391
, pp. 707-710
-
-
Yin, Y.1
Terauchi, Y.2
Solomon, G.G.3
Aizawa, S.4
Rangarajan, P.N.5
Yazaki, Y.6
Kadowaki, T.7
Barrett, J.C.8
-
18
-
-
0028978183
-
Mice lacking p21 undergo normal development but are defective in G1 checkpoint control
-
18. Deng C, Zhang P, Harper JW, Elledge SJ, Leder P (1995) Mice lacking p21 undergo normal development but are defective in G1 checkpoint control. Cell 675-684
-
(1995)
Cell
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
19
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
19. Brugarolas J, Chandrasekaran C, Gordon JI, Beach D, Jacks T, Hannon GJ (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377:552-557
-
(1995)
Nature
, vol.377
, pp. 552-557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Beach, D.4
Jacks, T.5
Hannon, G.J.6
-
20
-
-
0028070989
-
p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
-
20. Caelics C, Helmberg A, Karin M (1994) p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature 370:220-223
-
(1994)
Nature
, vol.370
, pp. 220-223
-
-
Caelles, C.1
Helmberg, A.2
Karin, M.3
-
21
-
-
0031303868
-
The apoptotic and transcriptional transactivation activities of p53 can be dissociated
-
21. Bissonnette N, Wasylyk B, Hunting DJ (1997) The apoptotic and transcriptional transactivation activities of p53 can be dissociated. Biochem Cell Biol 75:351-358
-
(1997)
Biochem Cell Biol
, vol.75
, pp. 351-358
-
-
Bissonnette, N.1
Wasylyk, B.2
Hunting, D.J.3
-
22
-
-
0029092356
-
Induction of apoptosis in HeLa cells by transactivation-deficient p53
-
22. Haupt Y, Rowan S, Shaulian E, Vousden K, Oren M (1995) Induction of apoptosis in HeLa cells by transactivation-deficient p53. Genes Dev 9:2170-2183
-
(1995)
Genes Dev
, vol.9
, pp. 2170-2183
-
-
Haupt, Y.1
Rowan, S.2
Shaulian, E.3
Vousden, K.4
Oren, M.5
-
23
-
-
0029143395
-
Essential role for p53-mediated transactivation in apoptosis but not growth suppression
-
23. Sabbatini P, Lin J, Levine AJ, White E (1995) Essential role for p53-mediated transactivation in apoptosis but not growth suppression. Genes Dev 9:2184-2192
-
(1995)
Genes Dev
, vol.9
, pp. 2184-2192
-
-
Sabbatini, P.1
Lin, J.2
Levine, A.J.3
White, E.4
-
24
-
-
0030013337
-
Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene mediated apoptosis
-
24. Attardi LD, Lowe SW, Brugarolas J, Jacks T (1996) Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene mediated apoptosis. EMBO J 15:3693-3701
-
(1996)
EMBO J
, vol.15
, pp. 3693-3701
-
-
Attardi, L.D.1
Lowe, S.W.2
Brugarolas, J.3
Jacks, T.4
-
25
-
-
0029585933
-
Transcriptional activation plays a role in the induction of apoptosis by transiently transfected p53
-
25. Yonish-Rouach E, Deguin V, Zaitchouk T, Breugnot C, Mishal Z, Jenkins JR, May E (1996) Transcriptional activation plays a role in the induction of apoptosis by transiently transfected p53. Oncogene 12:2197-2205
-
(1996)
Oncogene
, vol.12
, pp. 2197-2205
-
-
Yonish-Rouach, E.1
Deguin, V.2
Zaitchouk, T.3
Breugnot, C.4
Mishal, Z.5
Jenkins, J.R.6
May, E.7
-
26
-
-
0031806708
-
Characterisation of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest
-
26. Ryan KM, Vousden KH (1998) Characterisation of structural p53 mutants which show selective defects in apoptosis but not cell cycle arrest. Mol Cell Biol 18:3692-3698
-
(1998)
Mol Cell Biol
, vol.18
, pp. 3692-3698
-
-
Ryan, K.M.1
Vousden, K.H.2
-
27
-
-
0029823623
-
Relationship of sequence-specific transactivation and p53 regulated apoptosis in interleukin 3-dependent hematopoietic cells
-
27. Gottlieb E, Lindner S, Oren M (1996) Relationship of sequence-specific transactivation and p53 regulated apoptosis in interleukin 3-dependent hematopoietic cells. Cell Growth Diff 7:301-310
-
(1996)
Cell Growth Diff
, vol.7
, pp. 301-310
-
-
Gottlieb, E.1
Lindner, S.2
Oren, M.3
-
28
-
-
0029671112
-
Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo
-
28. Kitada S, Krajewski S, Miyashita T, Krajewska M, Reed JC (1996) Gamma-radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo. Oncogene 12:187-192
-
(1996)
Oncogene
, vol.12
, pp. 187-192
-
-
Kitada, S.1
Krajewski, S.2
Miyashita, T.3
Krajewska, M.4
Reed, J.C.5
-
29
-
-
0030689782
-
The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo
-
29. Reinke V, Lozano G (1997) The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo. Oncogene 15:1527-1534
-
(1997)
Oncogene
, vol.15
, pp. 1527-1534
-
-
Reinke, V.1
Lozano, G.2
-
30
-
-
0032528245
-
Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53
-
30. Resnick-Silverman L, St Clair S, Maurer M, Zhao K, Manfredi JJ (1998) Identification of a novel class of genomic DNA-binding sites suggests a mechanism for selectivity in target gene activation by the tumor suppressor protein p53. Genes Dev 12:2102-2107
-
(1998)
Genes Dev
, vol.12
, pp. 2102-2107
-
-
Resnick-Silverman, L.1
St Clair, S.2
Maurer, M.3
Zhao, K.4
Manfredi, J.J.5
-
31
-
-
0029783722
-
A mutant p53 that discriminates between p53 responsive genes cannot induce apoptosis
-
31. Friedlander P, Haupt Y, Prives C, Oren M (1996) A mutant p53 that discriminates between p53 responsive genes cannot induce apoptosis. Mol Cell Biol 16:4961-4971
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4961-4971
-
-
Friedlander, P.1
Haupt, Y.2
Prives, C.3
Oren, M.4
-
32
-
-
0029742781
-
Differential transcriptional activation of target cellular promotors by p53 mutants with impaired apoptotic function
-
32. Ludwig RL, Bates S, Vousden KH (1996) Differential transcriptional activation of target cellular promotors by p53 mutants with impaired apoptotic function. Mol Cell Biol 16:4952-4960
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4952-4960
-
-
Ludwig, R.L.1
Bates, S.2
Vousden, K.H.3
-
33
-
-
0029003061
-
Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
-
33. Wang Y, Prives C (1995) Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases Nature 376:88-89
-
(1995)
Nature
, vol.376
, pp. 88-89
-
-
Wang, Y.1
Prives, C.2
-
34
-
-
0030477012
-
Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes
-
34. Lohrum M, Scheidtmann KH (1996) Differential effects of phosphorylation of rat p53 on transactivation of promoters derived from different p53 responsive genes. Oncogene 13:2527-2539
-
(1996)
Oncogene
, vol.13
, pp. 2527-2539
-
-
Lohrum, M.1
Scheidtmann, K.H.2
-
35
-
-
0031587821
-
Recruitment of p300/CBP in p53-dependent signal pathways
-
35. Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, Kelly K (1997) Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89:1175-1184
-
(1997)
Cell
, vol.89
, pp. 1175-1184
-
-
Avantaggiati, M.L.1
Ogryzko, V.2
Gardner, K.3
Giordano, A.4
Levine, A.S.5
Kelly, K.6
-
36
-
-
0030973238
-
Binding and modulation of p53 by p300/CBP coactivators
-
36. Lill NL, Grossman SR, Ginsberg D, DeCaprio J, Livingston DM (1997) Binding and modulation of p53 by p300/CBP coactivators. Nature 387:823-827
-
(1997)
Nature
, vol.387
, pp. 823-827
-
-
Lill, N.L.1
Grossman, S.R.2
Ginsberg, D.3
DeCaprio, J.4
Livingston, D.M.5
-
37
-
-
0032575079
-
Functional interplay between p53 and E2F through coactivator p300
-
37. Lee CW, Sorensen TS, Shikama N, La Thangue N (1998) Functional interplay between p53 and E2F through coactivator p300. Oncogene 16:2695-2710
-
(1998)
Oncogene
, vol.16
, pp. 2695-2710
-
-
Lee, C.W.1
Sorensen, T.S.2
Shikama, N.3
La Thangue, N.4
-
38
-
-
0032127947
-
Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function
-
38. Thomas A, White E (1998) Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function. Genes Dev 12:1975-1985
-
(1998)
Genes Dev
, vol.12
, pp. 1975-1985
-
-
Thomas, A.1
White, E.2
-
39
-
-
0030812331
-
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other cancers
-
39. Kaghad M (1997) Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other cancers. Cell 90:809-819
-
(1997)
Cell
, vol.90
, pp. 809-819
-
-
Kaghad, M.1
-
40
-
-
0031564954
-
p73 is a human p53-related protein that can induce apoptosis
-
40. Jost CA, Marin MC, Kaelin W (1997) p73 is a human p53-related protein that can induce apoptosis. Nature 389:191-194
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin, W.3
-
41
-
-
0031852337
-
Cloning and functional analysis of human p51, which structurally and functionally resembles p53
-
41. Osada M, Ohba M, Kawahara C, Ishioka C, Kanamaru R, Katoh I, Ikawa Y, Nimura Y, Nakagawara A, Obinata M, Ikawa S (1998) Cloning and functional analysis of human p51, which structurally and functionally resembles p53. Nat Med 4:839-843
-
(1998)
Nat Med
, vol.4
, pp. 839-843
-
-
Osada, M.1
Ohba, M.2
Kawahara, C.3
Ishioka, C.4
Kanamaru, R.5
Katoh, I.6
Ikawa, Y.7
Nimura, Y.8
Nakagawara, A.9
Obinata, M.10
Ikawa, S.11
-
42
-
-
0031874340
-
A new human p53 homologue
-
42. Trink B, Okami K, Wu L, Sriuranpong V, Jen J, Sidransky D (1998) A new human p53 homologue. Nat Med 4:747-778
-
(1998)
Nat Med
, vol.4
, pp. 747-778
-
-
Trink, B.1
Okami, K.2
Wu, L.3
Sriuranpong, V.4
Jen, J.5
Sidransky, D.6
-
43
-
-
0032161624
-
p63, a p53 homologue at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
-
43. Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V, Andrews NC, Caput D, McKeon F (1998) p63, a p53 homologue at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 2:305-316
-
(1998)
Mol Cell
, vol.2
, pp. 305-316
-
-
Yang, A.1
Kaghad, M.2
Wang, Y.3
Gillett, E.4
Fleming, M.D.5
Dotsch, V.6
Andrews, N.C.7
Caput, D.8
McKeon, F.9
-
44
-
-
0032568037
-
Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis
-
44. Canman CE, Kastan MB (1998) Small contribution of G1 checkpoint control manipulation to modulation of p53-mediated apoptosis. Oncogene 16:957-966
-
(1998)
Oncogene
, vol.16
, pp. 957-966
-
-
Canman, C.E.1
Kastan, M.B.2
-
45
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
45. Polyak K, Waldman T, He T-C, Kinzler KW, Vogelstein B (1996) Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10:1945-1952
-
(1996)
Genes Dev
, vol.10
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.-C.3
Kinzler, K.W.4
Vogelstein, B.5
-
46
-
-
0028883179
-
Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
-
46. Miyashita T, Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299
-
(1995)
Cell
, vol.80
, pp. 293-299
-
-
Miyashita, T.1
Reed, J.C.2
-
47
-
-
0032146987
-
Bcl-2-family proteins: The role of the BH3 domains in apoptosis
-
47. Kelekar A, Thompson CB (1998) Bcl-2-family proteins: the role of the BH3 domains in apoptosis. Trends Cell Biol 8:324-330
-
(1998)
Trends Cell Biol
, vol.8
, pp. 324-330
-
-
Kelekar, A.1
Thompson, C.B.2
-
48
-
-
0028859541
-
Bax-deficient mice with lymphoid hyperplasia and male germ cell death
-
48. Knudson CM, Tung KSK, Tourtellote WG, Brown GAJ, Korsmeyer SJ (1995) Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270:96-99
-
(1995)
Science
, vol.270
, pp. 96-99
-
-
Knudson, C.M.1
Tung, K.S.K.2
Tourtellote, W.G.3
Brown, G.A.J.4
Korsmeyer, S.J.5
-
49
-
-
0030938089
-
Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
-
49. McCurrach ME, Connor TM, Knudson CM, Korsmeyer SJ, Lowe SW (1997) bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc Natl Acad Sci USA 94:2345-2349
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2345-2349
-
-
McCurrach, M.E.1
Connor, T.M.2
Knudson, C.M.3
Korsmeyer, S.J.4
Lowe, S.W.5
-
50
-
-
0031038137
-
Bax suppresses tumorigenesis and stimulates apoptosis in vivo
-
50. Yin C, Knudson CM, Korsmeyer SJ, Van DT (1997) Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 385:637-640
-
(1997)
Nature
, vol.385
, pp. 637-640
-
-
Yin, C.1
Knudson, C.M.2
Korsmeyer, S.J.3
Van, D.T.4
-
51
-
-
0032519859
-
Bax involvement in p53-mediated neuronal cell death
-
51. Xiang H, Kinoshita Y, Knudson CM, Korsmeyer SJ, Schwartzkroin PA, Morrison RS (1998) Bax involvement in p53-mediated neuronal cell death. J Neurosci 18:1363-1373
-
(1998)
J Neurosci
, vol.18
, pp. 1363-1373
-
-
Xiang, H.1
Kinoshita, Y.2
Knudson, C.M.3
Korsmeyer, S.J.4
Schwartzkroin, P.A.5
Morrison, R.S.6
-
52
-
-
0032575714
-
Death receptors: Signaling and modulation
-
52. Ashkenazi A, Dixit VM (1998) Death receptors: signaling and modulation. Science 281:1305-1308
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
53
-
-
0029003501
-
Wild-type p53 and a temperature sensitive mutant induce Fas/APO-1 expression
-
53. Owen-Schaub LB, Zhang W, Cusack JC, Angelo LS, Santee SM, Fujiwara T, Roth JA, Deisseroth AB, Zhang W-W, Kruzel E, Radinsky R (1995) Wild-type p53 and a temperature sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15:3032-3040
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3032-3040
-
-
Owen-Schaub, L.B.1
Zhang, W.2
Cusack, J.C.3
Angelo, L.S.4
Santee, S.M.5
Fujiwara, T.6
Roth, J.A.7
Deisseroth, A.B.8
Zhang, W.-W.9
Kruzel, E.10
Radinsky, R.11
-
54
-
-
0031743648
-
p53 activates the CD95 (APO 1/Fas) gene in response to DNA damage by anticancer drugs
-
in press
-
54. Muller M, Wilder S, Bannasch D, Israeli D, Lehlbach K, Li-Weber M, Friedmann SL, Galle PR, Stremmel W, Oren M, Krammer PH (1998) p53 activates the CD95 (APO 1/Fas) gene in response to DNA damage by anticancer drugs. J Exp Med (in press).
-
(1998)
J Exp Med
-
-
Muller, M.1
Wilder, S.2
Bannasch, D.3
Israeli, D.4
Lehlbach, K.5
Li-Weber, M.6
Friedmann, S.L.7
Galle, P.R.8
Stremmel, W.9
Oren, M.10
Krammer, P.H.11
-
55
-
-
0029935682
-
Involvement of the CD95 (APO 1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells
-
55. Friesen C, Herr I, Krammer PH, Debatin KM (1996) Involvement of the CD95 (APO 1/Fas) receptor/ligand system in drug-induced apoptosis in leukemia cells. Nat Med 2:574-577
-
(1996)
Nat Med
, vol.2
, pp. 574-577
-
-
Friesen, C.1
Herr, I.2
Krammer, P.H.3
Debatin, K.M.4
-
56
-
-
0031253977
-
KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
-
56. Wu GS, Burns TF, McDonald III ER, Jiang W, Meng R, Krantz ID, Kao G, Gan DD, Zhou JY, Muschel R, Hamilton SR, Spinner NB, Markowitz S, Wu G, El-Deiry W (1997) KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene. Nat Genet 17:141-143
-
(1997)
Nat Genet
, vol.17
, pp. 141-143
-
-
Wu, G.S.1
Burns, T.F.2
McDonald E.R. III3
Jiang, W.4
Meng, R.5
Krantz, I.D.6
Kao, G.7
Gan, D.D.8
Zhou, J.Y.9
Muschel, R.10
Hamilton, S.R.11
Spinner, N.B.12
Markowitz, S.13
Wu, G.14
El-Deiry, W.15
-
57
-
-
0032522463
-
p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha
-
57. Sheikh MS, Burns TF, Huang Y, Wu GS, Amundson S, Brooks KS, Fornace AJ, El-Deiry W (1998) p53-dependent and -independent regulation of the death receptor KILLER/DR5 gene expression in response to genotoxic stress and tumor necrosis factor alpha. Cancer Res 58:1593-1598
-
(1998)
Cancer Res
, vol.58
, pp. 1593-1598
-
-
Sheikh, M.S.1
Burns, T.F.2
Huang, Y.3
Wu, G.S.4
Amundson, S.5
Brooks, K.S.6
Fornace, A.J.7
El-Deiry, W.8
-
58
-
-
0032404536
-
The central executioners of apoptosis: Caspases or mitochondria?
-
58. Green D, Kroemer G (1998) The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol 8: 267-271
-
(1998)
Trends Cell Biol
, vol.8
, pp. 267-271
-
-
Green, D.1
Kroemer, G.2
-
59
-
-
0030930366
-
A model for p53 induced apoptosis
-
59. Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B (1997) A model for p53 induced apoptosis. Nature 389:300-305
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
60
-
-
0030448650
-
Identification of a novel p53 functional domain that is necessary for efficient growth suppression
-
60. Walker KK, Levine AJ (1996) Identification of a novel p53 functional domain that is necessary for efficient growth suppression. Proc Natl Acad Sci USA 93:15335-15340
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 15335-15340
-
-
Walker, K.K.1
Levine, A.J.2
-
61
-
-
0030798557
-
The polyproline region of p53 is required to activate apoptosis but not growth arrest
-
61. Sakamuro D, Sabbatini P, White E, Prendergast GC (1997) The polyproline region of p53 is required to activate apoptosis but not growth arrest. Oncogene 15:887-898
-
(1997)
Oncogene
, vol.15
, pp. 887-898
-
-
Sakamuro, D.1
Sabbatini, P.2
White, E.3
Prendergast, G.C.4
-
62
-
-
0032541325
-
The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression
-
62. Venot C, Maratrat M, Dureuil C, Conseiller E, Bracco L, Debussche L (1998) The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression. EMBO J 17:4668-4679
-
(1998)
EMBO J
, vol.17
, pp. 4668-4679
-
-
Venot, C.1
Maratrat, M.2
Dureuil, C.3
Conseiller, E.4
Bracco, L.5
Debussche, L.6
-
63
-
-
0028864667
-
Induction of the growth inhibitor IGF-binding protein 3 by p53
-
63. Buckbinder LR, Talbott S, Velasco-Miguel I, Takenaka B, Faha B, Seizinger BR, Kley N (1995) Induction of the growth inhibitor IGF-binding protein 3 by p53. Nature 377:646-649
-
(1995)
Nature
, vol.377
, pp. 646-649
-
-
Buckbinder, L.R.1
Talbott, S.2
Velasco-Miguel, I.3
Takenaka, B.4
Faha, B.5
Seizinger, B.R.6
Kley, N.7
-
64
-
-
0030972216
-
Insulin like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta 1 on programmed cell death through a p53-and IGF-independent mechanism
-
64. Rajah R, Valentinis B, Cohen P (1997) Insulin like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta 1 on programmed cell death through a p53-and IGF-independent mechanism. J Biol Chem 272:12181-12188
-
(1997)
J Biol Chem
, vol.272
, pp. 12181-12188
-
-
Rajah, R.1
Valentinis, B.2
Cohen, P.3
-
65
-
-
0031036879
-
The insulin-like growth factor i receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal
-
65. Prisco M, Kongo A, Rizzo MG, Sacchi A, Baserga R (1997) The insulin-like growth factor I receptor as a physiologically relevant target of p53 in apoptosis caused by interleukin-3 withdrawal. Mol Cell Biol 17:1084-1092
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1084-1092
-
-
Prisco, M.1
Kongo, A.2
Rizzo, M.G.3
Sacchi, A.4
Baserga, R.5
-
66
-
-
0028263811
-
c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
-
66. Harrington EA, Bennett MR, Fanidi A, Evan GI (1994) c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 13:3286-3295
-
(1994)
EMBO J
, vol.13
, pp. 3286-3295
-
-
Harrington, E.A.1
Bennett, M.R.2
Fanidi, A.3
Evan, G.I.4
-
67
-
-
0030802364
-
A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
-
67. Israeli D, Tessler E, Haupt Y, Elkeles A, Wilder S, Amson R, Telerman A, Oren M (1997) A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J 16:4384-4392
-
(1997)
EMBO J
, vol.16
, pp. 4384-4392
-
-
Israeli, D.1
Tessler, E.2
Haupt, Y.3
Elkeles, A.4
Wilder, S.5
Amson, R.6
Telerman, A.7
Oren, M.8
-
68
-
-
0027159087
-
Continuous c-fos expression precedes programmed cell death in vivo
-
68. Smeyne RJ, Vendrell M, Hayward M, Baker SJ, Miao GG, Schilling K, Robertson LM, Curran T, Morgan JI (1993) Continuous c-fos expression precedes programmed cell death in vivo. Nature 363:166-169
-
(1993)
Nature
, vol.363
, pp. 166-169
-
-
Smeyne, R.J.1
Vendrell, M.2
Hayward, M.3
Baker, S.J.4
Miao, G.G.5
Schilling, K.6
Robertson, L.M.7
Curran, T.8
Morgan, J.I.9
-
69
-
-
0025887476
-
Wild-type p53 can down-modulate the activity of various promotors
-
69. Ginsberg D, Mechta F, Yaniv M, Oren M (1991) Wild-type p53 can down-modulate the activity of various promotors. Proc Natl Acad Sci. USA 88:9979-9983
-
(1991)
Proc Natl Acad Sci. USA
, vol.88
, pp. 9979-9983
-
-
Ginsberg, D.1
Mechta, F.2
Yaniv, M.3
Oren, M.4
-
70
-
-
0025775929
-
Repression of the interleukin 6 gene promotor by p53 and the retinoblastoma susceptibility gene product
-
70. Santhanam U, Ray A, Seghal PB (1991) Repression of the interleukin 6 gene promotor by p53 and the retinoblastoma susceptibility gene product. Proc Natl Acad Sci USA 88: 7605-7609
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 7605-7609
-
-
Santhanam, U.1
Ray, A.2
Seghal, P.B.3
-
71
-
-
0026752654
-
Negative regulation of Rb expression by the p53 gene product
-
71. Shiio Y, Yamamoto T, Ymaguchi N (1992) Negative regulation of Rb expression by the p53 gene product. Proc Natl Acad Sci USA 89:5206-5210
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 5206-5210
-
-
Shiio, Y.1
Yamamoto, T.2
Ymaguchi, N.3
-
72
-
-
0026642078
-
Inhibition of viral and cellular promotors by wild-type p53
-
72. Subler M, Martin D, Deb S (1992) Inhibition of viral and cellular promotors by wild-type p53. J Virol 66:4757-4762
-
(1992)
J Virol
, vol.66
, pp. 4757-4762
-
-
Subler, M.1
Martin, D.2
Deb, S.3
-
73
-
-
0027318117
-
Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53
-
73. Mack DH, Vartikar J, Pipas JM, Laimins LA (1993) Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53. Nature 363:281-283
-
(1993)
Nature
, vol.363
, pp. 281-283
-
-
Mack, D.H.1
Vartikar, J.2
Pipas, J.M.3
Laimins, L.A.4
-
74
-
-
0028575705
-
Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein
-
74. Shen Y, Shenk T (1994) Relief of p53-mediated transcriptional repression by the adenovirus E1B 19-kDa protein or the cellular Bcl-2 protein. Proc Natl Acad Sci USA 91:8940-8944
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8940-8944
-
-
Shen, Y.1
Shenk, T.2
-
75
-
-
0028847563
-
Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein
-
75. Sabbatini P, Chiou SK, Rao L, White E (1995) Modulation of p53-mediated transcriptional repression and apoptosis by the adenovirus E1B 19K protein. Mol Cell Biol 15:1060-1070
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1060-1070
-
-
Sabbatini, P.1
Chiou, S.K.2
Rao, L.3
White, E.4
-
76
-
-
0029164446
-
The WT1 gene product stabilises p53 and inhibits p53-mediated apoptosis
-
76. Maheswaran S, Englert C, Bennet P, Heinrich G, Haber DA (1995) The WT1 gene product stabilises p53 and inhibits p53-mediated apoptosis. Genes Dev 9:2143-2156
-
(1995)
Genes Dev
, vol.9
, pp. 2143-2156
-
-
Maheswaran, S.1
Englert, C.2
Bennet, P.3
Heinrich, G.4
Haber, D.A.5
-
77
-
-
0029803281
-
Wild-type p53 negatively regulates the expression of a microtubule-associated protein
-
77. Murphy M, Hinman A, Levine AJ (1996) Wild-type p53 negatively regulates the expression of a microtubule-associated protein. Genes Dev 10:2971-2980
-
(1996)
Genes Dev
, vol.10
, pp. 2971-2980
-
-
Murphy, M.1
Hinman, A.2
Levine, A.J.3
-
78
-
-
0031593685
-
WAF-1 and results in apoptosis and tumor suppression
-
WAF-1 and results in apoptosis and tumor suppression. Nat Med 4: 835-838
-
(1998)
Nat Med
, vol.4
, pp. 835-838
-
-
Roperch, J.P.1
Alvaro, V.2
Prieur, S.3
Tuynder, M.4
Nemani, M.5
Lethrosne, F.6
Piouffre, L.7
Gendron, M.C.8
Israeli, D.9
Dausset, J.10
Oren, M.11
Amson, R.12
Telerman, A.13
-
79
-
-
0028989236
-
p53 modulation of TFIIH-associated nucleotide excision repair activity
-
79. Wang XW, Yeh H, Schaeffer L, Roy R, Moncollin V, Egly J-M, Wang Z, Friedberg EC, Evans MK, Taffe BG, Bohr VA, Weeda G, Hoeijmakers JHJ, Forrester K, Harris C (1995) p53 modulation of TFIIH-associated nucleotide excision repair activity. Nature Gen 10:188-195
-
(1995)
Nature Gen
, vol.10
, pp. 188-195
-
-
Wang, X.W.1
Yeh, H.2
Schaeffer, L.3
Roy, R.4
Moncollin, V.5
Egly, J.-M.6
Wang, Z.7
Friedberg, E.C.8
Evans, M.K.9
Taffe, B.G.10
Bohr, V.A.11
Weeda, G.12
Hoeijmakers, J.H.J.13
Forrester, K.14
Harris, C.15
-
80
-
-
0001166257
-
The XPB and XPD helicases are components of the p53-mediated apoptosis pathway
-
80. Wang XW, Vermeulen W, Coursen JD, Gibson M, Lupold SE, Forrester K, Xu G, Elmore L, Yeh H, Hoeijmakers JHJ, Harris C (1996) The XPB and XPD helicases are components of the p53-mediated apoptosis pathway. Genes Dev 10:1219-1232
-
(1996)
Genes Dev
, vol.10
, pp. 1219-1232
-
-
Wang, X.W.1
Vermeulen, W.2
Coursen, J.D.3
Gibson, M.4
Lupold, S.E.5
Forrester, K.6
Xu, G.7
Elmore, L.8
Yeh, H.9
Hoeijmakers, J.H.J.10
Harris, C.11
-
81
-
-
0030610565
-
The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro
-
81. Lu H, Fisher RP, Bailey P, Levine AJ (1997) The CDK7-cycH-p36 complex of transcription factor IIH phosphorylates p53, enhancing its sequence-specific DNA binding activity in vitro. Mol Cell Biol 17:5923-5934
-
(1997)
Mol Cell Biol
, vol.17
, pp. 5923-5934
-
-
Lu, H.1
Fisher, R.P.2
Bailey, P.3
Levine, A.J.4
-
82
-
-
0030724673
-
p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner
-
82. Ko LJ, Shieh SY, Chen X, Jayaraman L, Tamai K, Taya Y, Prives C, Pan ZQ (1997) p53 is phosphorylated by CDK7-cyclin H in a p36MAT1-dependent manner. Mol Cell Biol 17:7220-7229
-
(1997)
Mol Cell Biol
, vol.17
, pp. 7220-7229
-
-
Ko, L.J.1
Shieh, S.Y.2
Chen, X.3
Jayaraman, L.4
Tamai, K.5
Taya, Y.6
Prives, C.7
Pan, Z.Q.8
-
83
-
-
0032575750
-
Caspases: Enemies within
-
83. Thornberry NA, Lazebik Y (1998) Caspases: enemies within. Science 281:1312-1316
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebik, Y.2
-
84
-
-
0032127463
-
p53 facilitates pRb cleavage in IL-3-deprived cells: Novel pro-apoptotic activity of p53
-
84. Gottlieb E, Oren M (1998) p53 facilitates pRb cleavage in IL-3-deprived cells: novel pro-apoptotic activity of p53. EMBO J 17:3587-3596
-
(1998)
EMBO J
, vol.17
, pp. 3587-3596
-
-
Gottlieb, E.1
Oren, M.2
-
85
-
-
0032561471
-
Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system
-
85. Ding HF, McGill G, Rowan S, Schmaltz C, Shimamura A, Fisher DE (1998) Oncogene-dependent regulation of caspase activation by p53 protein in a cell-free system. J Biol Chem 273:28378-28383
-
(1998)
J Biol Chem
, vol.273
, pp. 28378-28383
-
-
Ding, H.F.1
McGill, G.2
Rowan, S.3
Schmaltz, C.4
Shimamura, A.5
Fisher, D.E.6
-
86
-
-
0032500793
-
Cell surface trafficking of fas: A rapid mechanism of p53-mediated apoptosis
-
86. Bennett M, Macdonald K, Chan S-W, Luzio JP, Simari R, Weissberg P (1998) Cell surface trafficking of fas: a rapid mechanism of p53-mediated apoptosis. Science 282:290-293
-
(1998)
Science
, vol.282
, pp. 290-293
-
-
Bennett, M.1
Macdonald, K.2
Chan, S.-W.3
Luzio, J.P.4
Simari, R.5
Weissberg, P.6
-
87
-
-
0029802591
-
p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
-
87. Chen X, Ko LJ, Jayaraman L, Prives C (1996) p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev 10:2438-2451
-
(1996)
Genes Dev
, vol.10
, pp. 2438-2451
-
-
Chen, X.1
Ko, L.J.2
Jayaraman, L.3
Prives, C.4
-
88
-
-
0030949069
-
A function in apoptosis other than transactivation inherent in the NH2-terminal domain of p53
-
88. Theis S, Atz J, Mueller LN, Roemer K (1997) A function in apoptosis other than transactivation inherent in the NH2-terminal domain of p53. Int J Cancer 71:858-866
-
(1997)
Int J Cancer
, vol.71
, pp. 858-866
-
-
Theis, S.1
Atz, J.2
Mueller, L.N.3
Roemer, K.4
-
89
-
-
0031056054
-
The murine C′-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells
-
89. Almog N, Li R, Peled A, Schwartz D, Wolkowicz R, Goldfinger N, Pei H, Rotter V (1997) The murine C′-terminally alternatively spliced form of p53 induces attenuated apoptosis in myeloid cells. Mol Cell Biol 17:713-722
-
(1997)
Mol Cell Biol
, vol.17
, pp. 713-722
-
-
Almog, N.1
Li, R.2
Peled, A.3
Schwartz, D.4
Wolkowicz, R.5
Goldfinger, N.6
Pei, H.7
Rotter, V.8
-
90
-
-
0032557649
-
Identification of a novel p53 functional domain that is necessary for mediating apoptosis
-
90. Zhu J, Zhou W, Jiang J, Chen X (1998) Identification of a novel p53 functional domain that is necessary for mediating apoptosis. J Biol Chem 273:13030-13036
-
(1998)
J Biol Chem
, vol.273
, pp. 13030-13036
-
-
Zhu, J.1
Zhou, W.2
Jiang, J.3
Chen, X.4
-
91
-
-
0032475878
-
Signaling to p53: Breaking the MDM2-p53 circuit
-
91. Prives C (1998) Signaling to p53: Breaking the MDM2-p53 circuit. Cell 95:5-8
-
(1998)
Cell
, vol.95
, pp. 5-8
-
-
Prives, C.1
-
92
-
-
0032539816
-
Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation
-
92. Kapoor M, Lozano G (1998) Functional activation of p53 via phosphorylation following DNA damage by UV but not gamma radiation. Proc Natl Acad Sci USA 95:2834-2837
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 2834-2837
-
-
Kapoor, M.1
Lozano, G.2
-
93
-
-
0032568633
-
Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389
-
93. Lu H, Taya Y, Ikeda M, Levine AJ (1998) Ultraviolet radiation, but not gamma radiation or etoposide-induced DNA damage, results in the phosphorylation of the murine p53 protein at serine-389. Proc Natl Acad Sci USA 95:6399-6402
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6399-6402
-
-
Lu, H.1
Taya, Y.2
Ikeda, M.3
Levine, A.J.4
-
94
-
-
0030031757
-
Induction of HL-60 cells to undergo apoptosis is determined by high levels of wild-type p53 protein whereas differentiation of the cells is mediated by lower p53 levels
-
94. Ronen D, Schwartz D, Teitz Y, Goldfinger N, Rotter V (1996) Induction of HL-60 cells to undergo apoptosis is determined by high levels of wild-type p53 protein whereas differentiation of the cells is mediated by lower p53 levels. Cell Growth Differ 7:21-30
-
(1996)
Cell Growth Differ
, vol.7
, pp. 21-30
-
-
Ronen, D.1
Schwartz, D.2
Teitz, Y.3
Goldfinger, N.4
Rotter, V.5
-
95
-
-
0031663617
-
ATM: From gene to function
-
95. Rotman G, Shiloh Y (1998) ATM: from gene to function. Hum Mol Genet 7:1555-1563
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1555-1563
-
-
Rotman, G.1
Shiloh, Y.2
-
96
-
-
0031435944
-
DNA damage induces phosphorylation of the amino terminus of p53
-
96. Siliciano JD, Canman CE, Taya Y, Sakaguchi K, Appella E, Kastan MB (1997) DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev 11:3471-3481
-
(1997)
Genes Dev
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
97
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
97. Banin S, Moyal L, Shieh S-Y, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, Ziv Y (1998) Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281:1674-1677
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.-Y.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
98
-
-
0032508608
-
Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
-
98. Canman CE, Lim D-S, Cimprich KA, Taya Y, Tamai K, Sakaguchi K, Appella E, Kastan MB, Siciliano JD (1998) Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281:1677-1679
-
(1998)
Science
, vol.281
, pp. 1677-1679
-
-
Canman, C.E.1
Lim, D.-S.2
Cimprich, K.A.3
Taya, Y.4
Tamai, K.5
Sakaguchi, K.6
Appella, E.7
Kastan, M.B.8
Siciliano, J.D.9
-
99
-
-
0031840253
-
ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins
-
99. Waterman MJ, Stavridi ES, Waterman JL, Halazonetis TD (1998) ATM-dependent activation of p53 involves dephosphorylation and association with 14-3-3 proteins. Nat Genet 19:175-178
-
(1998)
Nat Genet
, vol.19
, pp. 175-178
-
-
Waterman, M.J.1
Stavridi, E.S.2
Waterman, J.L.3
Halazonetis, T.D.4
-
100
-
-
0030667522
-
ATM selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
-
100. Barlow C, Brown KD, Deng CX, Tagle DA, Wynshaw-Boris A (1997) ATM selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nat Genet 17:453-456
-
(1997)
Nat Genet
, vol.17
, pp. 453-456
-
-
Barlow, C.1
Brown, K.D.2
Deng, C.X.3
Tagle, D.A.4
Wynshaw-Boris, A.5
-
101
-
-
0032524070
-
Requirement for ATM in ionizing radiation-induced cell death in the developing central nervous system
-
101. Herzog KH, Chong MJ, Kapsetaki M, Morgan JI, McKinnon PJ (1998) Requirement for ATM in ionizing radiation-induced cell death in the developing central nervous system. Science 280:1089-1091
-
(1998)
Science
, vol.280
, pp. 1089-1091
-
-
Herzog, K.H.1
Chong, M.J.2
Kapsetaki, M.3
Morgan, J.I.4
McKinnon, P.J.5
-
102
-
-
0032575705
-
A matter of life and cell death
-
102. Evan G, Littlewood T (1998) A matter of life and cell death. Science 281:1317-1322
-
(1998)
Science
, vol.281
, pp. 1317-1322
-
-
Evan, G.1
Littlewood, T.2
-
103
-
-
0028331229
-
Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
-
103. White AE, Livanos EM, Tlsty TD (1994) Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 8:666-677
-
(1994)
Genes Dev
, vol.8
, pp. 666-677
-
-
White, A.E.1
Livanos, E.M.2
Tlsty, T.D.3
-
104
-
-
0028088250
-
Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells
-
104. Reznikoff CA, Belair C, Savelieva E, Zhai Y, Pfeifer K, Yeager T, Thompson KJ, DeVries S, Bindley C, Newton MA, et al (1994) Long-term genome stability and minimal genotypic and phenotypic alterations in HPV16 E7-, but not E6-, immortalized human uroepithelial cells. Genes Dev 8:2227-2240
-
(1994)
Genes Dev
, vol.8
, pp. 2227-2240
-
-
Reznikoff, C.A.1
Belair, C.2
Savelieva, E.3
Zhai, Y.4
Pfeifer, K.5
Yeager, T.6
Thompson, K.J.7
DeVries, S.8
Bindley, C.9
Newton, M.A.10
-
105
-
-
0027262606
-
Stabilisation of the p53 tumor suppressor is induced by adenovirus 5 EIA and accompanies apoptosis
-
105. Lowe SW, Ruley HE (1993) Stabilisation of the p53 tumor suppressor is induced by adenovirus 5 EIA and accompanies apoptosis. Genes Dev 7:535-545
-
(1993)
Genes Dev
, vol.7
, pp. 535-545
-
-
Lowe, S.W.1
Ruley, H.E.2
-
106
-
-
0028227260
-
Apoptosis or retinoblastoma: Alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53
-
106. Howes KA, Ransom N, Papermaster DS, Lasudry JG, Albert DM, Windle JJ (1994) Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev 8:1300-1310
-
(1994)
Genes Dev
, vol.8
, pp. 1300-1310
-
-
Howes, K.A.1
Ransom, N.2
Papermaster, D.S.3
Lasudry, J.G.4
Albert, D.M.5
Windle, J.J.6
-
107
-
-
0028334011
-
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: Implications for tumor suppressor gene function in development
-
107. Pan H, Griep AE (1994) Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development. Genes Dev 8:1285-1299
-
(1994)
Genes Dev
, vol.8
, pp. 1285-1299
-
-
Pan, H.1
Griep, A.E.2
-
108
-
-
0027451668
-
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
-
108. Lowe SW, Ruley HE, Jacks T, Housman DE (1993) p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
109
-
-
0028323294
-
Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells
-
109. Lowe SW, Jacks T, Housman DE, Ruley HE (1994) Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc Natl Acad Sci USA 91:2026-2030
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2026-2030
-
-
Lowe, S.W.1
Jacks, T.2
Housman, D.E.3
Ruley, H.E.4
-
110
-
-
0027934570
-
p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens
-
110. Morgenbesser SD, Williams BO, Jacks T, DePinho RA (1994) p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature 371:72-74
-
(1994)
Nature
, vol.371
, pp. 72-74
-
-
Morgenbesser, S.D.1
Williams, B.O.2
Jacks, T.3
DePinho, R.A.4
-
112
-
-
0032504784
-
p19ARF links the tumor suppressor p53 to ras
-
112. Palmero I, Pantoja C, Serrano M (1998) p19ARF links the tumor suppressor p53 to ras. Nature 395:125-126
-
(1998)
Nature
, vol.395
, pp. 125-126
-
-
Palmero, I.1
Pantoja, C.2
Serrano, M.3
-
113
-
-
0032145569
-
Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalisation
-
113. Zindy F, Eischen CM, Randle DH, Kamijo T, Cleveland JL, Sherr CJ, Roussel MF (1998) Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalisation. Genes Dev 12:2424-2433
-
(1998)
Genes Dev
, vol.12
, pp. 2424-2433
-
-
Zindy, F.1
Eischen, C.M.2
Randle, D.H.3
Kamijo, T.4
Cleveland, J.L.5
Sherr, C.J.6
Roussel, M.F.7
-
114
-
-
0032146795
-
E1A signaling to p53 involves the p19(ARF) tumor suppressor
-
114. de Stanchina E, McCurrach ME, Zindy F, Shieh SY, Ferbeyre G, Samuelson AV, Prives C, Roussel MF, Sherr CJ, Lowe SW (1998) E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev 12:2434-2342
-
(1998)
Genes Dev
, vol.12
, pp. 2434-12342
-
-
De Stanchina, E.1
McCurrach, M.E.2
Zindy, F.3
Shieh, S.Y.4
Ferbeyre, G.5
Samuelson, A.V.6
Prives, C.7
Roussel, M.F.8
Sherr, C.J.9
Lowe, S.W.10
-
115
-
-
0032504783
-
p14ARF links the tumor suppressors Rb and p53
-
115. Bates S, Phillips AC, Clarke PA, Stott F, Peters G, Ludwig RL, Vousden KH (1998) p14ARF links the tumor suppressors Rb and p53. Nature 395:124-125
-
(1998)
Nature
, vol.395
, pp. 124-125
-
-
Bates, S.1
Phillips, A.C.2
Clarke, P.A.3
Stott, F.4
Peters, G.5
Ludwig, R.L.6
Vousden, K.H.7
-
116
-
-
0032493350
-
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2
-
116. Kamijo T, Weber JD, Zambetti G, Zindy E, Roussel MF, Sherr CJ (1998) Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2. Proc Natl Acad Sci USA 95:8292-8297
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8292-8297
-
-
Kamijo, T.1
Weber, J.D.2
Zambetti, G.3
Zindy, E.4
Roussel, M.F.5
Sherr, C.J.6
-
117
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
117. Pomerantz J, Schreiber AN, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon CC, DePinho RA (1998) The Ink4a tumor suppressor gene product, p19ARF, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92:713-723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber, A.N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon, C.C.11
DePinho, R.A.12
-
118
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
118. Stott FJ, Bates S, James MC, McConnell BB, Starborg M, Brookes S, Palmero I, Ryan K, Hara E, Vousden KH, Peters G (1998) The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J 17:5001-5014
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
119
-
-
0032549711
-
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
-
119. Zhang Y, Xiong Y, Yarbrough WG (1998) ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 92:725-734
-
(1998)
Cell
, vol.92
, pp. 725-734
-
-
Zhang, Y.1
Xiong, Y.2
Yarbrough, W.G.3
-
120
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
120. Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G, Sherr CJ (1997) Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91:649-659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
121
-
-
0028169994
-
p53-dependent apoptosis suppresses tumor growth and progression in vivo
-
121. Symonds H, Krall L, Remington L, Saenz RM, Lowe S, Jacks T, Van DT (1994) p53-dependent apoptosis suppresses tumor growth and progression in vivo. Cell 78:703-711
-
(1994)
Cell
, vol.78
, pp. 703-711
-
-
Symonds, H.1
Krall, L.2
Remington, L.3
Saenz, R.M.4
Lowe, S.5
Jacks, T.6
Van, D.T.7
-
122
-
-
0030021748
-
Specific loss of apoptotic but not cell cycle arrest function in a human tumor derived mutant p53
-
122. Rowan S, Ludwig RL, Haupt Y, Bates S, Lu X, Oren M, Vousden KH (1996) Specific loss of apoptotic but not cell cycle arrest function in a human tumor derived mutant p53. EMBO J 15:827-838
-
(1996)
EMBO J
, vol.15
, pp. 827-838
-
-
Rowan, S.1
Ludwig, R.L.2
Haupt, Y.3
Bates, S.4
Lu, X.5
Oren, M.6
Vousden, K.H.7
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