-
1
-
-
0030933152
-
The genetic defect in ataxia-telangiectasia
-
Lavin, M.F. and Shiloh, Y. (1997) The genetic defect in ataxia-telangiectasia. Annu. Rev. Immunol., 15, 177-202.
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 177-202
-
-
Lavin, M.F.1
Shiloh, Y.2
-
2
-
-
0031466618
-
Ataxia-telangiectasia and the Nijmegen breakage syndrome: Related disorders but genes apart
-
Shiloh, Y. (1997) Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart. Annu. Rev. Genet., 31, 635-662.
-
(1997)
Annu. Rev. Genet.
, vol.31
, pp. 635-662
-
-
Shiloh, Y.1
-
3
-
-
0002636559
-
Ataxia-telangiectasia
-
Vogelstein, B. and Kinzler, K.W. (eds), McGraw-Hill, New York
-
Gatti, R.A. (1998) Ataxia-telangiectasia. In Vogelstein, B. and Kinzler, K.W. (eds), The Genetic Basis of Human Cancer. McGraw-Hill, New York, pp. 275-300.
-
(1998)
The Genetic Basis of Human Cancer
, pp. 275-300
-
-
Gatti, R.A.1
-
4
-
-
0030910037
-
p53 and ATM: Cell cycle, cell death, and cancer
-
Morgan, S.E. and Kastan, M. (1997) p53 and ATM: cell cycle, cell death, and cancer. Adv. Cancer Res., 71, 1-25.
-
(1997)
Adv. Cancer Res.
, vol.71
, pp. 1-25
-
-
Morgan, S.E.1
Kastan, M.2
-
5
-
-
0031472044
-
Cell cycle signaling: ATM displays its many talents
-
Westphal, C.H. (1997) Cell cycle signaling: ATM displays its many talents. Curr. Biol., 7, R789-R792.
-
(1997)
Curr. Biol.
, vol.7
-
-
Westphal, C.H.1
-
6
-
-
0029875247
-
DNA damage and cell cycle checkpoints
-
Kaufmann, W.K. and Paules, R.S. (1996) DNA damage and cell cycle checkpoints. FASEB J., 10, 238-247.
-
(1996)
FASEB J.
, vol.10
, pp. 238-247
-
-
Kaufmann, W.K.1
Paules, R.S.2
-
7
-
-
0029093638
-
Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia
-
Khanna, K.K., Beamish, H., Yan, J., Hobson, K., Williams R., Dunn, I. and Lavin, M.F. (1995) Nature of G1/S cell cycle checkpoint defect in ataxia-telangiectasia. Oncogene, 11, 609-618.
-
(1995)
Oncogene
, vol.11
, pp. 609-618
-
-
Khanna, K.K.1
Beamish, H.2
Yan, J.3
Hobson, K.4
Williams, R.5
Dunn, I.6
Lavin, M.F.7
-
9
-
-
0027428513
-
The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia-telangiectasia and normal human cells
-
Liu, V.F. and Weaver, D.T. (1993) The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia-telangiectasia and normal human cells. Mol. Cell. Biol., 13, 7222-7231.
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 7222-7231
-
-
Liu, V.F.1
Weaver, D.T.2
-
10
-
-
0029970505
-
Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia-telangiectasia and reduced in aged normal fibroblasts
-
Cheng, X., Cheong, N., Wang, Y. and Iliakis, G. (1996) Ionizing radiation-induced phosphorylation of RPA p34 is deficient in ataxia-telangiectasia and reduced in aged normal fibroblasts. Radiother. Oncol., 39, 43-52.
-
(1996)
Radiother. Oncol.
, vol.39
, pp. 43-52
-
-
Cheng, X.1
Cheong, N.2
Wang, Y.3
Iliakis, G.4
-
11
-
-
0030858642
-
Dissociation of radiation-induced phosphorylation of replication protein A from the S-phase checkpoint
-
Morgan, S.E. and Kastan, M. (1997) Dissociation of radiation-induced phosphorylation of replication protein A from the S-phase checkpoint. Cancer Res., 57, 3386-3389.
-
(1997)
Cancer Res.
, vol.57
, pp. 3386-3389
-
-
Morgan, S.E.1
Kastan, M.2
-
12
-
-
0028985945
-
2 checkpoint function in cells from individuals with familial cancer syndromes
-
2 checkpoint function in cells from individuals with familial cancer syndromes. Cancer Res., 55, 1763-1773.
-
(1995)
Cancer Res.
, vol.55
, pp. 1763-1773
-
-
Paules, R.S.1
Levedakou, E.N.2
Wilson, S.J.3
Innes, C.L.4
Rhodes, N.5
Tlsty, T.D.6
Galloway, D.A.7
Donehower, L.A.8
Tainsky, M.A.9
Kaufmann, W.K.10
-
13
-
-
0029829249
-
Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation
-
Beamish, H., Williams, R., Chen, P. and Lavin, M.F. (1996) Defect in multiple cell cycle checkpoints in ataxia-telangiectasia postirradiation. J. Biol. Chem., 271, 20486-20493.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 20486-20493
-
-
Beamish, H.1
Williams, R.2
Chen, P.3
Lavin, M.F.4
-
14
-
-
0029134790
-
Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation
-
Shafman, T.D., Saleem, A., Kyriakis, J., Weichselbaum, R., Kharbanda, S. and Kufe D.W. (1995) Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Res., 55, 3242-3245.
-
(1995)
Cancer Res.
, vol.55
, pp. 3242-3245
-
-
Shafman, T.D.1
Saleem, A.2
Kyriakis, J.3
Weichselbaum, R.4
Kharbanda, S.5
Kufe, D.W.6
-
15
-
-
0030925565
-
Ataxia-telangiectasia mutated protein activates c-Abl tyrosine kinase in response to ionizing radiation
-
Baskaran, R., Wood, L.D., Whitaker, L.L., Canman, C.E., Morgan, S.E., Xu, Y., Barlow, C., Baltimore, D., Wynshaw-Boris, A., Kastan, M.B. and Wang, J.Y.J. (1997) Ataxia-telangiectasia mutated protein activates c-Abl tyrosine kinase in response to ionizing radiation. Nature, 387, 516-519.
-
(1997)
Nature
, vol.387
, pp. 516-519
-
-
Baskaran, R.1
Wood, L.D.2
Whitaker, L.L.3
Canman, C.E.4
Morgan, S.E.5
Xu, Y.6
Barlow, C.7
Baltimore, D.8
Wynshaw-Boris, A.9
Kastan, M.B.10
Wang, J.Y.J.11
-
16
-
-
0030992749
-
Interaction between ATM protein and c-Abl in response to DNA damage
-
Shafman, T., Khanna, K.K., Kedar, P., Spring, K., Kozlov, S., Yen, T., Hobson, K., Gatei, M., Zhang, N., Watters, D., Egerton, M., Shiloh, Y., Kharbanda, S., Kufe, D. and Lavin, M.F. (1997) Interaction between ATM protein and c-Abl in response to DNA damage. Nature, 387, 520-523.
-
(1997)
Nature
, vol.387
, pp. 520-523
-
-
Shafman, T.1
Khanna, K.K.2
Kedar, P.3
Spring, K.4
Kozlov, S.5
Yen, T.6
Hobson, K.7
Gatei, M.8
Zhang, N.9
Watters, D.10
Egerton, M.11
Shiloh, Y.12
Kharbanda, S.13
Kufe, D.14
Lavin, M.F.15
-
17
-
-
0029002103
-
Ataxia-telangiectasia: Closer to unraveling the mystery
-
Shiloh, Y. (1995) Ataxia-telangiectasia: closer to unraveling the mystery. Eur. J. Hum. Genet., 3, 116-138.
-
(1995)
Eur. J. Hum. Genet.
, vol.3
, pp. 116-138
-
-
Shiloh, Y.1
-
18
-
-
0030048511
-
High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines
-
Luo, C.-M., Tang, W., Mekeel, K.L., DeFrank, J.S., Anné, P.R. and Powell, S.N. (1996) High frequency and error-prone DNA recombination in ataxia telangiectasia cell lines. J. Biol. Chem., 271, 4497-4503.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 4497-4503
-
-
Luo, C.-M.1
Tang, W.2
Mekeel, K.L.3
DeFrank, J.S.4
Anné, P.R.5
Powell, S.N.6
-
19
-
-
0030807476
-
Identification of defective illegitimate recombinational repair of oxidatively-induced DNA double-strand breaks in ataxia-telangiectasia cells
-
Dar, M.E., Winters, T.A. and Jorgensen, T.J. (1997) Identification of defective illegitimate recombinational repair of oxidatively-induced DNA double-strand breaks in ataxia-telangiectasia cells. Mutat. Res. 384, 169-179.
-
(1997)
Mutat. Res.
, vol.384
, pp. 169-179
-
-
Dar, M.E.1
Winters, T.A.2
Jorgensen, T.J.3
-
20
-
-
0030750923
-
Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
-
Foray, N., Priestley, A., Alsbeih, G., Badie, C., Capulas, E.P., Arlett, C.F. and Malaise, E.P. (1997) Hypersensitivity of ataxia telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks. Int. J. Radiat. Biol., 72, 271-283.
-
(1997)
Int. J. Radiat. Biol.
, vol.72
, pp. 271-283
-
-
Foray, N.1
Priestley, A.2
Alsbeih, G.3
Badie, C.4
Capulas, E.P.5
Arlett, C.F.6
Malaise, E.P.7
-
21
-
-
0031259793
-
Ataxia-telangiectasia: Is ATM a sensor of oxidative damage and stress?
-
Rotman, G. and Shiloh, Y. (1997) Ataxia-telangiectasia: is ATM a sensor of oxidative damage and stress? BioEssays, 19, 911-917.
-
(1997)
BioEssays
, vol.19
, pp. 911-917
-
-
Rotman, G.1
Shiloh, Y.2
-
23
-
-
0031157079
-
Correspondence re: M.Stephen Meyn, ataxia telangiectasia and cellular responses to DNA damage
-
Brown, J.M. (1997) Correspondence re: M.Stephen Meyn, ataxia telangiectasia and cellular responses to DNA damage. Cancer Res., 57, 2313-2315.
-
(1997)
Cancer Res.
, vol.57
, pp. 2313-2315
-
-
Brown, J.M.1
-
24
-
-
0028980925
-
Chromosome end associations, telomeres and telomease activity in ataxia telangiectasia cells
-
Pandita, T.K., Pathak, S. and Geard, C.R. (1995) Chromosome end associations, telomeres and telomease activity in ataxia telangiectasia cells. Cytogenet. Cell Genet., 71, 86-93.
-
(1995)
Cytogenet. Cell Genet.
, vol.71
, pp. 86-93
-
-
Pandita, T.K.1
Pathak, S.2
Geard, C.R.3
-
25
-
-
0030565541
-
Reduced telomere length in ataxia-telangiectasia fibroblasts
-
Xia, S.J., Shammas, M.A. and Shmookler Reis, R.J. (1996) Reduced telomere length in ataxia-telangiectasia fibroblasts. Mutat. Res., 364, 1-11.
-
(1996)
Mutat. Res.
, vol.364
, pp. 1-11
-
-
Xia, S.J.1
Shammas, M.A.2
Shmookler Reis, R.J.3
-
26
-
-
0029681361
-
Accelerated telomere shortening in ataxia telangiectasia
-
Metcalfe J.A., Parkhill, J., Campbell L., Stacey, M., Biggs, P., Byrd, P.J. and Taylor, A.M.R. (1996) Accelerated telomere shortening in ataxia telangiectasia. Nature Genet., 13, 350-353.
-
(1996)
Nature Genet.
, vol.13
, pp. 350-353
-
-
Metcalfe, J.A.1
Parkhill, J.2
Campbell, L.3
Stacey, M.4
Biggs, P.5
Byrd, P.J.6
Taylor, A.M.R.7
-
27
-
-
0030911886
-
Defective signalling through the B cell antigen receptor in ataxia-telangiectasia cells
-
Khanna, K.K., Yan, J., Watters, D., Hobson K., Beamish, H., Spring, K., Shiloh, Y., Gatti, R.A. and Lavin, M.F. (1997) Defective signalling through the B cell antigen receptor in ataxia-telangiectasia cells. J. Biol. Chem., 272, 9489-9495.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9489-9495
-
-
Khanna, K.K.1
Yan, J.2
Watters, D.3
Hobson, K.4
Beamish, H.5
Spring, K.6
Shiloh, Y.7
Gatti, R.A.8
Lavin, M.F.9
-
28
-
-
0027230816
-
Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia
-
Kondo, N., Inoue, S., Nishimura, S., Kasahara, K., Kameyama, T., Miwa Y., Lorenzo, P.R. and Orii, T. (1993) Defective calcium-dependent signal transduction in T lymphocytes of ataxia-telangiectasia. Scand. J. Immunol., 38, 45-48.
-
(1993)
Scand. J. Immunol.
, vol.38
, pp. 45-48
-
-
Kondo, N.1
Inoue, S.2
Nishimura, S.3
Kasahara, K.4
Kameyama, T.5
Miwa, Y.6
Lorenzo, P.R.7
Orii, T.8
-
29
-
-
7344225050
-
Defective potassium currents in ataxia telangiectasia
-
Los Angeles, CA
-
Reinhart, P.M., D'Souza, T., Rhodes, N., Foster, C.D., Ziv, Y., Kirsch, D.G., Shiloh, Y., Kastan, M.B. and Gilmer, T.M. (1998) Defective potassium currents in ataxia telangiectasia. Annual Meeting of the Society for Neuroscience, Los Angeles, CA.
-
(1998)
Annual Meeting of the Society for Neuroscience
-
-
Reinhart, P.M.1
D'Souza, T.2
Rhodes, N.3
Foster, C.D.4
Ziv, Y.5
Kirsch, D.G.6
Shiloh, Y.7
Kastan, M.B.8
Gilmer, T.M.9
-
30
-
-
0029057336
-
A single ataxia-telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y. Vanagaite, L., Tagle, D.A., Smith, S., Uziel, T., Sfez, S., Ashkenazi, M., Pecker, I., Frydman, M., Harnik, R., Patanjali, S.R., Simmons, A., Clines, G.A., Sartiel, A., Gatti, R.A., Chessa, L., Sanal, O., Lavin, M.F., Jaspers, N.G.J., Taylor, A.M.R., Arlett, C.F., Miki, T., Weissman, S.M., Lovett, M., Collins, F.S. and Shiloh, Y. (1995) A single ataxia-telangiectasia gene with a product similar to PI-3 kinase. Science, 268, 1749-1753.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
Ashkenazi, M.11
Pecker, I.12
Frydman, M.13
Harnik, R.14
Patanjali, S.R.15
Simmons, A.16
Clines, G.A.17
Sartiel, A.18
Gatti, R.A.19
Chessa, L.20
Sanal, O.21
Lavin, M.F.22
Jaspers, N.G.J.23
Taylor, A.M.R.24
Arlett, C.F.25
Miki, T.26
Weissman, S.M.27
Lovett, M.28
Collins, F.S.29
Shiloh, Y.30
more..
-
31
-
-
0028827312
-
The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
-
Savitsky, K., Sfez, S., Tagle, D.A., Ziv, Y., Sartiel, A., Collins, F.S., Shiloh, Y. and Rotman, G. (1995) The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum. Mol. Genet., 4, 2025-2032.
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 2025-2032
-
-
Savitsky, K.1
Sfez, S.2
Tagle, D.A.3
Ziv, Y.4
Sartiel, A.5
Collins, F.S.6
Shiloh, Y.7
Rotman, G.8
-
32
-
-
0030871226
-
Ataxia-telangiectasia: Structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression
-
Savitsky, K., Platzer, M., Uziel, T., Gilad, S., Sartiel, A., Rosenthal, A., Elroy-Stein, O., Shiloh, Y and Rotman, G. (1997) Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression. Nucleic Acids Res., 25, 1678-1684.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1678-1684
-
-
Savitsky, K.1
Platzer, M.2
Uziel, T.3
Gilad, S.4
Sartiel, A.5
Rosenthal, A.6
Elroy-Stein, O.7
Shiloh, Y.8
Rotman, G.9
-
33
-
-
0029807481
-
A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: Amino acid sequence, structure and expression studies
-
Byrd, P.J., Cooper, P.R., Slankovic, T., Kullar, H.S., Watts, G.D., Robinson, P.J. and Taylor, A.M.R. (1996) A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies. Hum. Mol. Genet., 5, 1785-1791.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 1785-1791
-
-
Byrd, P.J.1
Cooper, P.R.2
Slankovic, T.3
Kullar, H.S.4
Watts, G.D.5
Robinson, P.J.6
Taylor, A.M.R.7
-
34
-
-
19144369245
-
Identification and characterization of a new gene physically linked to the ATM gene
-
Imai, T., Yamauchi, M., Seki, N., Sugawara, T., Saito, T., Matsuda, Y., Ito, H., Nagase, T., Nomura, N. and Hori, T. (1996) Identification and characterization of a new gene physically linked to the ATM gene. Genome Res., 6, 439-447.
-
(1996)
Genome Res.
, vol.6
, pp. 439-447
-
-
Imai, T.1
Yamauchi, M.2
Seki, N.3
Sugawara, T.4
Saito, T.5
Matsuda, Y.6
Ito, H.7
Nagase, T.8
Nomura, N.9
Hori, T.10
-
35
-
-
6844226199
-
CAND3: A ubiquitously expressed gene immediately adjacent and in opposite transcriptional orientation to the ATM gene at 11q23.1
-
Chen, X., Yang, L., Udar, N., Liang, T., Uhrhammer, N., Xu, S., Bay, J.-O., Wang, X., Dandakar, S., Chiplunkar, S., Klisak, I., Telatar, M., Yang, H., Concannon, P. and Gatti, R.A. (1997) CAND3: A ubiquitously expressed gene immediately adjacent and in opposite transcriptional orientation to the ATM gene at 11q23.1. Mamm. Genome, 8, 129-133.
-
(1997)
Mamm. Genome
, vol.8
, pp. 129-133
-
-
Chen, X.1
Yang, L.2
Udar, N.3
Liang, T.4
Uhrhammer, N.5
Xu, S.6
Bay, J.-O.7
Wang, X.8
Dandakar, S.9
Chiplunkar, S.10
Klisak, I.11
Telatar, M.12
Yang, H.13
Concannon, P.14
Gatti, R.A.15
-
36
-
-
0032520093
-
Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry
-
Zhao, J., Dynlacht, B., Imai, T., Hori, T. and Harlow, E. (1998) Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes Dev., 12, 456-461.
-
(1998)
Genes Dev.
, vol.12
, pp. 456-461
-
-
Zhao, J.1
Dynlacht, B.2
Imai, T.3
Hori, T.4
Harlow, E.5
-
37
-
-
0030797708
-
Recombinant ATM protein complements the cellular A-T phenotype
-
Ziv, Y., Bar-Shira, A., Pecker, I., Russell, P., Jorgensen, T.J., Tsarfati, I. and Shiloh, Y. (1997) Recombinant ATM protein complements the cellular A-T phenotype. Oncogene, 15, 159-167.
-
(1997)
Oncogene
, vol.15
, pp. 159-167
-
-
Ziv, Y.1
Bar-Shira, A.2
Pecker, I.3
Russell, P.4
Jorgensen, T.J.5
Tsarfati, I.6
Shiloh, Y.7
-
38
-
-
0030860784
-
Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype
-
Zhang, N., Chen, P., Khanna, K.K., Scott, S., Gatei, M., Kozlov, S., Watters, D., Spring, K., Yen, T. and Lavin, M.F. (1997) Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. Proc. Natl Acad. Sci. USA, 94, 8021-8026.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 8021-8026
-
-
Zhang, N.1
Chen, P.2
Khanna, K.K.3
Scott, S.4
Gatei, M.5
Kozlov, S.6
Watters, D.7
Spring, K.8
Yen, T.9
Lavin, M.F.10
-
39
-
-
0032551989
-
An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells
-
in press
-
Zhang, N., Chen, P., Gatei, M., Scott, S., Khanna, K.K. and Lavin, M.F. (1998) An anti-sense construct of full-length ATM cDNA imposes a radiosensitive phenotype on normal cells. Oncogene, in press.
-
(1998)
Oncogene
-
-
Zhang, N.1
Chen, P.2
Gatei, M.3
Scott, S.4
Khanna, K.K.5
Lavin, M.F.6
-
40
-
-
0030969423
-
Fragments of ATM which have dominant-negative or complementing activity
-
Morgan, S.E., Lovly, C., Pandita, T.K., Shiloh, Y and Kastan, M. (1997) Fragments of ATM which have dominant-negative or complementing activity. Mol. Cell. Biol., 17, 2020-2029.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 2020-2029
-
-
Morgan, S.E.1
Lovly, C.2
Pandita, T.K.3
Shiloh, Y.4
Kastan, M.5
-
41
-
-
0030977349
-
Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family
-
Hoekstra, M.F. (1997) Responses to DNA damage and regulation of cell cycle checkpoints by the ATM protein kinase family. Curr. Opin. Genet. Dev., 7, 170-175.
-
(1997)
Curr. Opin. Genet. Dev.
, vol.7
, pp. 170-175
-
-
Hoekstra, M.F.1
-
42
-
-
0030922250
-
DNA-PK: At the cross-roads of biochemistry and genetics
-
Jeggo, P.A. (1997) DNA-PK: at the cross-roads of biochemistry and genetics. Mutat. Res., 384, 1-14.
-
(1997)
Mutat. Res.
, vol.384
, pp. 1-14
-
-
Jeggo, P.A.1
-
43
-
-
0029827367
-
The Schizosaccharomyces pombe rad3 checkpoint gene
-
Bentley, N.J., Holtzman, D.A., Flaggs, G., Keegan, K.S., DeMaggio, A., Ford, J.C., Hoekstra, M. and Carr, A.M. (1996) The Schizosaccharomyces pombe rad3 checkpoint gene. EMBO J., 15, 6641-6651.
-
(1996)
EMBO J.
, vol.15
, pp. 6641-6651
-
-
Bentley, N.J.1
Holtzman, D.A.2
Flaggs, G.3
Keegan, K.S.4
DeMaggio, A.5
Ford, J.C.6
Hoekstra, M.7
Carr, A.M.8
-
44
-
-
9244229490
-
cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
-
Cimprich, K.A., Shin, T.B., Keith, C.T. and Schreiber, S.L. (1996) cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc. Natl Acad. Sci. USA, 93, 2850-2855.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2850-2855
-
-
Cimprich, K.A.1
Shin, T.B.2
Keith, C.T.3
Schreiber, S.L.4
-
45
-
-
0030881836
-
Phosphorylation of the translational represser PHAS-I by the mammalian target of rapamycin
-
Brunn, G.J., Hudson C.C., Sekulic, A., Williams, J.M., Hosoi, H., Houghton, P.J., Lawrence, J.C. and Abraham, R.T. (1997) Phosphorylation of the translational represser PHAS-I by the mammalian target of rapamycin. Science, 277, 99-101.
-
(1997)
Science
, vol.277
, pp. 99-101
-
-
Brunn, G.J.1
Hudson, C.C.2
Sekulic, A.3
Williams, J.M.4
Hosoi, H.5
Houghton, P.J.6
Lawrence, J.C.7
Abraham, R.T.8
-
46
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett, P.E., Barrow, R.K., Cohen, N.A., Snyder, S.H. and Sabatini, D.M. (1998) RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl Acad. Sci. USA, 95, 1432-1437.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
47
-
-
0030707562
-
TOR signalling and control of cell growth
-
Thomas, G. and Hall, M.N. (1997) TOR signalling and control of cell growth. Curr. Opin. Cell Biol. 9, 782-787.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
48
-
-
10244227923
-
The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes
-
Keegan, K.S., Holtzman, D.A., Plug, A.W., Christenson, E.R., Brainerd, E.E., Flaggs, G., Bentley, N.J., Taylor, E.M., Meyn, M.S., Moss, S.B., Carr, A.M., Ashley, T. and Hoekstra, M.F. (1996) The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes Dev., 10, 2423-2437.
-
(1996)
Genes Dev.
, vol.10
, pp. 2423-2437
-
-
Keegan, K.S.1
Holtzman, D.A.2
Plug, A.W.3
Christenson, E.R.4
Brainerd, E.E.5
Flaggs, G.6
Bentley, N.J.7
Taylor, E.M.8
Meyn, M.S.9
Moss, S.B.10
Carr, A.M.11
Ashley, T.12
Hoekstra, M.F.13
-
49
-
-
0030476720
-
The product of the ATM gene is a 370-kDa nuclear phosphoprotein
-
Chen, G. and Lee, E.Y.P. (1996) The product of the ATM gene is a 370-kDa nuclear phosphoprotein. J. Biol. Chem., 271, 33693-33697.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 33693-33697
-
-
Chen, G.1
Lee, E.Y.P.2
-
50
-
-
0032543723
-
Atm expression patterns suggest a contribution from the peripheral nervous system to the phenotype of ataxia-telangiectasia
-
Soares, H.D., Morgan, J.I. and McKinnon, P.J. (1998) Atm expression patterns suggest a contribution from the peripheral nervous system to the phenotype of ataxia-telangiectasia. Neuroscience, 86, 1045-1054.
-
(1998)
Neuroscience
, vol.86
, pp. 1045-1054
-
-
Soares, H.D.1
Morgan, J.I.2
McKinnon, P.J.3
-
51
-
-
0030472725
-
Analysis of the ATM protein in wild-type and ataxia-telangiectasia cells
-
Lakin, N.D., Weber, P., Stankovic, T., Rottinghaus, S.T., Taylor, A.M.R. and Jackson, S.P. (1996) Analysis of the ATM protein in wild-type and ataxia-telangiectasia cells. Oncogene, 13, 2707-2716.
-
(1996)
Oncogene
, vol.13
, pp. 2707-2716
-
-
Lakin, N.D.1
Weber, P.2
Stankovic, T.3
Rottinghaus, S.T.4
Taylor, A.M.R.5
Jackson, S.P.6
-
52
-
-
0031047915
-
The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not upregulated following genome damage
-
Brown, K.D., Ziv, Y., Sadanandan, S.N., Chessa, L., Collins. F.S., Shiloh, Y. and Tagle, D.A. (1997) The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not upregulated following genome damage. Proc. Natl Acad. Sci. USA, 94, 1840-1845.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 1840-1845
-
-
Brown, K.D.1
Ziv, Y.2
Sadanandan, S.N.3
Chessa, L.4
Collins, F.S.5
Shiloh, Y.6
Tagle, D.A.7
-
53
-
-
8244245266
-
Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms
-
Watters, D., Khanna, K.K., Beamish, H., Birrell, G., Spring, K., Kedar, P., Gatei, M., Stenzel, D., Hobson, K., Kozlov, S., Zhang, N., Farell, A., Ramsay, J., Gatti, R. and Lavin, M. (1997) Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms. Oncogene, 14, 1911-1921.
-
(1997)
Oncogene
, vol.14
, pp. 1911-1921
-
-
Watters, D.1
Khanna, K.K.2
Beamish, H.3
Birrell, G.4
Spring, K.5
Kedar, P.6
Gatei, M.7
Stenzel, D.8
Hobson, K.9
Kozlov, S.10
Zhang, N.11
Farell, A.12
Ramsay, J.13
Gatti, R.14
Lavin, M.15
-
54
-
-
0032492544
-
Cloning and expression of the ataxia-telangiectasia gene in baculovirus
-
Scott, S.P., Zhang, N., Khanna, K.K., Khromykh, A., Hobson K., Watters, D. and Lavin M.F. (1998) Cloning and expression of the ataxia-telangiectasia gene in baculovirus. Biochem. Biophys. Res. Commun., 245, 144-148.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.245
, pp. 144-148
-
-
Scott, S.P.1
Zhang, N.2
Khanna, K.K.3
Khromykh, A.4
Hobson, K.5
Watters, D.6
Lavin, M.F.7
-
55
-
-
0001183734
-
Ataxia-telangiectasia
-
Vinken, P.J., Bruyn, G.W. and Klawans, H.L. (eds), Elsevier Scientific Publishers, Amsterdam
-
Sedgwick, R.P. and Boder, E. (1991) Ataxia-telangiectasia. In Vinken, P.J., Bruyn, G.W. and Klawans, H.L. (eds), Handbook of Clinical Neurology, Vol. 16. Elsevier Scientific Publishers, Amsterdam, pp. 347-423.
-
(1991)
Handbook of Clinical Neurology
, vol.16
, pp. 347-423
-
-
Sedgwick, R.P.1
Boder, E.2
-
56
-
-
15844426692
-
Aim-deficient mice: A paradigm of ataxia-telangiectasia
-
Barlow, C., Hirotsune, S., Paylor, R., Liyanage, M., Eckhaus, M., Collins, F., Shiloh, Y., Crawley, J.N., Ried, T., Tagle, D. and Wynshaw-Boris, A. (1996) Aim-deficient mice: a paradigm of ataxia-telangiectasia. Cell, 86, 159-171.
-
(1996)
Cell
, vol.86
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
Shiloh, Y.7
Crawley, J.N.8
Ried, T.9
Tagle, D.10
Wynshaw-Boris, A.11
-
57
-
-
0029844048
-
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects and thymic lymphoma
-
Xu, Y., Ashley, T., Brainerd, E.E., Bronson, R.T., Meyn, S.M. and Baltimore, D. (1996) Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects and thymic lymphoma. Genes Dev., 10, 2411-2422.
-
(1996)
Genes Dev.
, vol.10
, pp. 2411-2422
-
-
Xu, Y.1
Ashley, T.2
Brainerd, E.E.3
Bronson, R.T.4
Meyn, S.M.5
Baltimore, D.6
-
58
-
-
0030724981
-
ATM and RPA in meiotic chromosome synapsis and recombination
-
Plug, A.W., Peters, A.H.F.M., Xu, Y., Keegan, K.S., Hoekstra, M.F., Baltimore, D., deBoer, P. and Ashley, T. (1997) ATM and RPA in meiotic chromosome synapsis and recombination. Nature Genet., 17, 457-461.
-
(1997)
Nature Genet.
, vol.17
, pp. 457-461
-
-
Plug, A.W.1
Peters, A.H.F.M.2
Xu, Y.3
Keegan, K.S.4
Hoekstra, M.F.5
Baltimore, D.6
DeBoer, P.7
Ashley, T.8
-
59
-
-
0030829001
-
A DNA damage checkpoint meets the cell cycle engine
-
Weinert, T. (1997) A DNA damage checkpoint meets the cell cycle engine. Science, 277, 1450-1451.
-
(1997)
Science
, vol.277
, pp. 1450-1451
-
-
Weinert, T.1
-
60
-
-
0031470835
-
Checkpoint pathways come of age
-
Nurse, P. (1997) Checkpoint pathways come of age. Cell, 91, 865-867.
-
(1997)
Cell
, vol.91
, pp. 865-867
-
-
Nurse, P.1
-
61
-
-
13144282737
-
Aim-dependent interactions of a mammalian Chk1 homolog with meiotic chromosomes
-
Flaggs, G., Plug, A.W., Dunks, K.M., Mundt, K.E., Ford, J.C., Quiggle, M.R.E., Taylor, E.M., Westphal, C.H., Ashley, T., Hoekstra, M.F. and Carr, A.M. (1997) Aim-dependent interactions of a mammalian Chk1 homolog with meiotic chromosomes. Curr. Biol., 7, 977-986.
-
(1997)
Curr. Biol.
, vol.7
, pp. 977-986
-
-
Flaggs, G.1
Plug, A.W.2
Dunks, K.M.3
Mundt, K.E.4
Ford, J.C.5
Quiggle, M.R.E.6
Taylor, E.M.7
Westphal, C.H.8
Ashley, T.9
Hoekstra, M.F.10
Carr, A.M.11
-
62
-
-
0030713080
-
Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles
-
Barlow, C., Liyanage, M., Moens, P.B., Deng, C.X., Ried, T. and Wynshaw-Boris, A. (1997) Partial rescue of the prophase I defects of Atm-deficient mice by p53 and p21 null alleles. Nature Genet., 17, 462-466.
-
(1997)
Nature Genet.
, vol.17
, pp. 462-466
-
-
Barlow, C.1
Liyanage, M.2
Moens, P.B.3
Deng, C.X.4
Ried, T.5
Wynshaw-Boris, A.6
-
63
-
-
0031016990
-
ATM gene product phosphorylates IκB-α
-
Jung, M., Kondratyev, A., Lee, S., Dimtchev, A. and Dritschilo, A. (1997) ATM gene product phosphorylates IκB-α. Cancer Res., 57, 24-27.
-
(1997)
Cancer Res.
, vol.57
, pp. 24-27
-
-
Jung, M.1
Kondratyev, A.2
Lee, S.3
Dimtchev, A.4
Dritschilo, A.5
-
64
-
-
0028126506
-
PHAS-I as a link between mitogen-activated protein kinase and translation initiation
-
Lin, T.-A, Kong, X., Haystead, T.A.J., Pause, A., Belsham, G., Sonenberg, N. and Lawrence, J.C. Jr (1994) PHAS-I as a link between mitogen-activated protein kinase and translation initiation. Science, 266, 653-656.
-
(1994)
Science
, vol.266
, pp. 653-656
-
-
Lin, T.-A.1
Kong, X.2
Haystead, T.A.J.3
Pause, A.4
Belsham, G.5
Sonenberg, N.6
Lawrence Jr., J.C.7
-
65
-
-
0031435944
-
DNA damage induces phosphorylation of the amino terminus of p53
-
Siliciano, J.D., Canman, C.E., Taya, Y., Sakaguchi, K., Appella, E. and Kastan, M.B. (1997) DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev., 11, 3471-3481.
-
(1997)
Genes Dev.
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
66
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh, S.-Y., Ikeda M., Taya, Y. and Prives, C. (1997) DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell, 91, 325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.-Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
67
-
-
0029098225
-
Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents
-
Kharbanda, S., Ren, R., Pandey, P., Shafman, T.D., Feller, S.M., Weichselbaum, R.R. and Kufe, D.W. (1995) Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents. Nature, 376, 785-788.
-
(1995)
Nature
, vol.376
, pp. 785-788
-
-
Kharbanda, S.1
Ren, R.2
Pandey, P.3
Shafman, T.D.4
Feller, S.M.5
Weichselbaum, R.R.6
Kufe, D.W.7
-
69
-
-
7344238660
-
Atm binds β-adaptin: A novel explanation for pleiotropic abnormalities in ataxia telangiectasia
-
in press
-
Lim, D.-S., Kirsch, D.G., Canman, C.E., Ahn, J.-H., Ziv, Y., Newman, L.S., Damell, R.B., Shiloh, Y. and Kastan, M.B. (1998) Atm binds β-adaptin: a novel explanation for pleiotropic abnormalities in ataxia telangiectasia. Proc. Natl Acad. Sci. USA, in press.
-
(1998)
Proc. Natl Acad. Sci. USA
-
-
Lim, D.-S.1
Kirsch, D.G.2
Canman, C.E.3
Ahn, J.-H.4
Ziv, Y.5
Newman, L.S.6
Damell, R.B.7
Shiloh, Y.8
Kastan, M.B.9
-
70
-
-
0030805899
-
Diversity of ATM mutations detected in patients with ataxia-telangiectasia
-
Concannon, P. and Gatti, R.A. (1997) Diversity of ATM mutations detected in patients with ataxia-telangiectasia. Hum. Mutat., 10, 100-107.
-
(1997)
Hum. Mutat.
, vol.10
, pp. 100-107
-
-
Concannon, P.1
Gatti, R.A.2
-
71
-
-
0031611465
-
Identification of ATM mutations using extended RT-PCR and restriction endonuclease fingerprinting, and elucidation of the repertoire of A-T mutations in Israel
-
Gilad, S., Khosravi, R., Harnik, R., Ziv, Y., Shkedy, D., Galanty, Y. Frydman, M., Levi, J., Sanal, O., Chessa, L., Smeets, D., Shiloh, Y. and Bar-Shira, A. (1998) Identification of ATM mutations using extended RT-PCR and restriction endonuclease fingerprinting, and elucidation of the repertoire of A-T mutations in Israel. Hum. Mutat., 11, 69-75.
-
(1998)
Hum. Mutat.
, vol.11
, pp. 69-75
-
-
Gilad, S.1
Khosravi, R.2
Harnik, R.3
Ziv, Y.4
Shkedy, D.5
Galanty, Y.6
Frydman, M.7
Levi, J.8
Sanal, O.9
Chessa, L.10
Smeets, D.11
Shiloh, Y.12
Bar-Shira, A.13
-
72
-
-
17344362697
-
ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: Expression of mutant ATM and the risk of leukaemia, lymphoma and breast cancer
-
Stankovic, T., Kidd, A.M.J., Suttcliffe, A., McGuire, G.M., Robinson, P., Weber, P., Bedenham, T., Bradwell, A.R., Easton, D.F., Lennox, G.G., Haites. N., Byrd, P.J. and Taylor, A.M.R. (1998) ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukaemia, lymphoma and breast cancer. Am. J. Hum. Genet., 62, 334-345.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 334-345
-
-
Stankovic, T.1
Kidd, A.M.J.2
Suttcliffe, A.3
McGuire, G.M.4
Robinson, P.5
Weber, P.6
Bedenham, T.7
Bradwell, A.R.8
Easton, D.F.9
Lennox, G.G.10
Haites, N.11
Byrd, P.J.12
Taylor, A.M.R.13
-
73
-
-
0343380661
-
Ataxia-telangiectasia: Identification and detection of founder-effect mutations in the ATM gene in ethnic populations
-
Telatar, M., Teraoka, S., Wang, Z., Chun, H.H., Liang, T., Castellvi-Bel, S., Udar, N., Borresen, A.-L., Chessa, L., Bematowska-Matuszkievicz, E., Porras, O., Watanabe, M., Junker, A., Concannon, P. and Gatti, R.A. (1998) Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations. Am. J Hum. Genet., 62, 86-97.
-
(1998)
Am. J Hum. Genet.
, vol.62
, pp. 86-97
-
-
Telatar, M.1
Teraoka, S.2
Wang, Z.3
Chun, H.H.4
Liang, T.5
Castellvi-Bel, S.6
Udar, N.7
Borresen, A.-L.8
Chessa, L.9
Bematowska-Matuszkievicz, E.10
Porras, O.11
Watanabe, M.12
Junker, A.13
Concannon, P.14
Gatti, R.A.15
-
74
-
-
10544235695
-
Ataxia-telangiectasia: Founder effect among North African Jews
-
Gilad, S., Bar-Shira, A., Harnik, R., Shkedy, D., Ziv, Y., Khosravi, R., Brown, K., Vanagaite, L., Xu, G., Frydman, M., Lavin, M.F., Hill, D., Tagle, D.A. and Shiloh, Y. (1996) Ataxia-telangiectasia: founder effect among North African Jews. Hum. Mol. Genet., 5, 2033-2037.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 2033-2037
-
-
Gilad, S.1
Bar-Shira, A.2
Harnik, R.3
Shkedy, D.4
Ziv, Y.5
Khosravi, R.6
Brown, K.7
Vanagaite, L.8
Xu, G.9
Frydman, M.10
Lavin, M.F.11
Hill, D.12
Tagle, D.A.13
Shiloh, Y.14
-
75
-
-
0031868136
-
Identical mutation in 55% of the ATM alleles in 11 Norweigian A-T families: Evidence for a founder effect
-
in press
-
Laake, K., Telatar, M., Geitvik, G.A., Hansen, R., Heiberg, A., Andersen, A., Gatti, R.A. and Borresen-Dale, A.-L. (1998) Identical mutation in 55% of the ATM alleles in 11 Norweigian A-T families: evidence for a founder effect. Eur. J. Hum. Genet., in press.
-
(1998)
Eur. J. Hum. Genet.
-
-
Laake, K.1
Telatar, M.2
Geitvik, G.A.3
Hansen, R.4
Heiberg, A.5
Andersen, A.6
Gatti, R.A.7
Borresen-Dale, A.-L.8
-
76
-
-
13344269672
-
Predominance of null mutations in ataxia-telangiectasia
-
Gilad, S., Khosravi, R., Shkedy, D., Uziel, T., Ziv, Y., Savitsky, K., Rotman, G., Smith, S., Chessa, L., Jorgensen, T.J., Harnik, R., Frydman, M., Sanal, O., Portnoi, S., Goldwicz, Z., Jaspers, N.G.J., Gatti, R.A., Lenoir, G., Lavin, M.F., Tatsumi, K., Wegner, R.D., Shiloh, Y and Bar-Shira, A. (1996) Predominance of null mutations in ataxia-telangiectasia. Hum. Mol. Genet., 5, 433-439.
-
(1996)
Hum. Mol. Genet.
, vol.5
, pp. 433-439
-
-
Gilad, S.1
Khosravi, R.2
Shkedy, D.3
Uziel, T.4
Ziv, Y.5
Savitsky, K.6
Rotman, G.7
Smith, S.8
Chessa, L.9
Jorgensen, T.J.10
Harnik, R.11
Frydman, M.12
Sanal, O.13
Portnoi, S.14
Goldwicz, Z.15
Jaspers, N.G.J.16
Gatti, R.A.17
Lenoir, G.18
Lavin, M.F.19
Tatsumi, K.20
Wegner, R.D.21
Shiloh, Y.22
Bar-Shira, A.23
more..
-
77
-
-
0029819493
-
Mutations associated with variant phenotypes in ataxia-telangiectasia
-
McConville, C.M., Stankovic, T., Byrd, P.J., McGuire, G.M., Yao, Q.-Y., Lennox, G.G. and Taylor, A.M.R. (1996) Mutations associated with variant phenotypes in ataxia-telangiectasia. Am. J. Hum. Genet., 59, 320-330.
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 320-330
-
-
McConville, C.M.1
Stankovic, T.2
Byrd, P.J.3
McGuire, G.M.4
Yao, Q.-Y.5
Lennox, G.G.6
Taylor, A.M.R.7
-
78
-
-
17344370225
-
Genotype-phenotype relationships in ataxia-telangiectasia (A-T) and A-T variants
-
Gilad, S., Chessa, L., Khosravi, R., Russell, P., Galanty, Y., Piane, M., Gatti, R.A., Jorgensen, T.J., Shiloh, Y. and Bar-Shira, A. (1998) Genotype-phenotype relationships in ataxia-telangiectasia (A-T) and A-T variants. Am. J. Hum. Genet., 62, 551-561.
-
(1998)
Am. J. Hum. Genet.
, vol.62
, pp. 551-561
-
-
Gilad, S.1
Chessa, L.2
Khosravi, R.3
Russell, P.4
Galanty, Y.5
Piane, M.6
Gatti, R.A.7
Jorgensen, T.J.8
Shiloh, Y.9
Bar-Shira, A.10
-
79
-
-
0030797830
-
Biallelic mutations in the ATM gene in T-prolymphocytic leukemia
-
Stilgenbauer, S., Schaffner, C., Litters, A., Liebish, P., Gilad, S., Bar-Shira, A., James, M.R., Lichter, P. and Dohner, H. (1997) Biallelic mutations in the ATM gene in T-prolymphocytic leukemia. Nature Med., 10, 1155-1159.
-
(1997)
Nature Med.
, vol.10
, pp. 1155-1159
-
-
Stilgenbauer, S.1
Schaffner, C.2
Litters, A.3
Liebish, P.4
Gilad, S.5
Bar-Shira, A.6
James, M.R.7
Lichter, P.8
Dohner, H.9
-
80
-
-
16944367148
-
Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia
-
Vorechovsky, I., Luo, L., Dyer, M.J.S., Catovsky, D., Amlot, P.L., Yaxley, J., Foroni, L., Hammarstrom, L., Webster, A.D.B. and Yuille, M.A.R. (1997) Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia. Nature Genet., 17, 96-99.
-
(1997)
Nature Genet.
, vol.17
, pp. 96-99
-
-
Vorechovsky, I.1
Luo, L.2
Dyer, M.J.S.3
Catovsky, D.4
Amlot, P.L.5
Yaxley, J.6
Foroni, L.7
Hammarstrom, L.8
Webster, A.D.B.9
Yuille, M.A.R.10
-
81
-
-
6844258870
-
ATM is usually rearranged in T-cell prolymphocytic leukemia
-
Yuille, M.A.R., Coignet, L.J.A., Abraham, S.M., Yaqub, F., Luo, L., Matutes, E., Brito-Babapulle, V., Vorechovsky, I., Dyer, M.J.S. and Catovsky, D. (1998) ATM is usually rearranged in T-cell prolymphocytic leukemia. Oncogene, 16, 789-796.
-
(1998)
Oncogene
, vol.16
, pp. 789-796
-
-
Yuille, M.A.R.1
Coignet, L.J.A.2
Abraham, S.M.3
Yaqub, F.4
Luo, L.5
Matutes, E.6
Brito-Babapulle, V.7
Vorechovsky, I.8
Dyer, M.J.S.9
Catovsky, D.10
-
82
-
-
0032525111
-
Inactivation of the ATM gene in T-cell prolymphocytic leukemias
-
in press
-
Stoppa-Lyonnet, D., Soulier, J., Lauge, A., Dastot, H., Garand, R., Sigaux, F. and Stern, M.H. (1998) Inactivation of the ATM gene in T-cell prolymphocytic leukemias. Blood, in press.
-
(1998)
Blood
-
-
Stoppa-Lyonnet, D.1
Soulier, J.2
Lauge, A.3
Dastot, H.4
Garand, R.5
Sigaux, F.6
Stern, M.H.7
-
83
-
-
0030051855
-
Leukemia and lymphoma in ataxia telangiectasia
-
Taylor, A.M.R., Metcalfe, J.A., Thick, J. and Mak, Y.F. (1996) Leukemia and lymphoma in ataxia telangiectasia. Blood, 87, 423-438.
-
(1996)
Blood
, vol.87
, pp. 423-438
-
-
Taylor, A.M.R.1
Metcalfe, J.A.2
Thick, J.3
Mak, Y.F.4
-
84
-
-
0029848286
-
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
-
Elson, A., Wang, Y., Daugherty, C.J., Morton, C.C., Zhou, F., Campos-Torres, J. and Leder, P. (1996) Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc. Natl Acad. Sci. USA, 93, 13084-13089.
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 13084-13089
-
-
Elson, A.1
Wang, Y.2
Daugherty, C.J.3
Morton, C.C.4
Zhou, F.5
Campos-Torres, J.6
Leder, P.7
-
85
-
-
0032524070
-
Requirement of Atm in ionizing radiation-induced cell death in the developing central nervous system
-
Herzog, K.H., Chong, M., Kapsetaki, M., Morgan, J.I. and McKinnon, P.J. (1998) Requirement of Atm in ionizing radiation-induced cell death in the developing central nervous system. Science, 280, 1089-1091.
-
(1998)
Science
, vol.280
, pp. 1089-1091
-
-
Herzog, K.H.1
Chong, M.2
Kapsetaki, M.3
Morgan, J.I.4
McKinnon, P.J.5
-
86
-
-
0029821651
-
Dual roles of ATM in the cellular response to radiation and in cell growth control
-
Xu, Y and Baltimore, D. (1996) Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev., 10, 2401-2410.
-
(1996)
Genes Dev.
, vol.10
, pp. 2401-2410
-
-
Xu, Y.1
Baltimore, D.2
-
87
-
-
0030941281
-
Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints
-
Westphal, C.H., Schmaltz, C., Rowan, S., Elson, A., Fisher, D.E. and Leder P. (1997) Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints. Cancer Res., 57, 1664-1667.
-
(1997)
Cancer Res.
, vol.57
, pp. 1664-1667
-
-
Westphal, C.H.1
Schmaltz, C.2
Rowan, S.3
Elson, A.4
Fisher, D.E.5
Leder, P.6
-
88
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
El-Deiry, W.S., Harper, J.W., O'Connor, P.M., Velculescu, V.E., Canman, C.E., Jackma, J., Pietenpol, J.A., Burrell, M., Hill, D.E., Wang, Y., Wiman, K.G., Mercer, W.E., Kastan, M.B., Kohn, K.W., Elledge, S.J., Kinzler, K.W. and Vogelstein, B. (1994) WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res., 54, 1169-1174.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
Velculescu, V.E.4
Canman, C.E.5
Jackma, J.6
Pietenpol, J.A.7
Burrell, M.8
Hill, D.E.9
Wang, Y.10
Wiman, K.G.11
Mercer, W.E.12
Kastan, M.B.13
Kohn, K.W.14
Elledge, S.J.15
Kinzler, K.W.16
Vogelstein, B.17
-
89
-
-
0031474756
-
Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice
-
Wang, Y.A., Elson, A. and Leder, P. (1997) Loss of p21 increases sensitivity to ionizing radiation and delays the onset of lymphoma in atm-deficient mice. Proc. Natl Acad. Sci. USA, 94, 14590-14595.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 14590-14595
-
-
Wang, Y.A.1
Elson, A.2
Leder, P.3
-
90
-
-
0029014910
-
V(D)J recombination and the cell cycle
-
Lin, W.-C. and Desiderio, S. (1995) V(D)J recombination and the cell cycle. Immunol. Today, 16, 279-289.
-
(1995)
Immunol. Today
, vol.16
, pp. 279-289
-
-
Lin, W.-C.1
Desiderio, S.2
-
91
-
-
0030879563
-
atm and p53 cooperate in apoptosis and suppression of tumorigenesis, hut not in resistance to acute radiation toxicity
-
Westphal, C.H., Rowan, S., Schmaltz, C., Elson, A., Fisher, D.E. and Leder, P. (1997) atm and p53 cooperate in apoptosis and suppression of tumorigenesis, hut not in resistance to acute radiation toxicity. Nature Genet., 16, 397-401.
-
(1997)
Nature Genet.
, vol.16
, pp. 397-401
-
-
Westphal, C.H.1
Rowan, S.2
Schmaltz, C.3
Elson, A.4
Fisher, D.E.5
Leder, P.6
-
92
-
-
0028118111
-
Tumor spectrum analysis in p53-mutant mice
-
Jacks, T., Remington, L., Williams, B.O., Schmitt, E.M., Halachmi, S., Bronson, R.T. and Weinberg, R.A. (1994) Tumor spectrum analysis in p53-mutant mice. Curr. Biol., 4, 1-7.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1-7
-
-
Jacks, T.1
Remington, L.2
Williams, B.O.3
Schmitt, E.M.4
Halachmi, S.5
Bronson, R.T.6
Weinberg, R.A.7
-
93
-
-
0028168643
-
p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis
-
Kemp, C.J., Wheldon, T. and Balmain, A. (1994) p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis. Nature Genet., 8, 66-69.
-
(1994)
Nature Genet.
, vol.8
, pp. 66-69
-
-
Kemp, C.J.1
Wheldon, T.2
Balmain, A.3
-
94
-
-
0030667522
-
Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways
-
Barlow, C., Brown, K.D., Deng, C.X., Tagle, D.A. and Wynshaw-Boris, A. (1997) Atm selectively regulates distinct p53-dependent cell-cycle checkpoint and apoptotic pathways. Nature Genet., 17, 453-456.
-
(1997)
Nature Genet.
, vol.17
, pp. 453-456
-
-
Barlow, C.1
Brown, K.D.2
Deng, C.X.3
Tagle, D.A.4
Wynshaw-Boris, A.5
-
95
-
-
0027258466
-
Thymocyte apoptosis induced by p53-dependent and independent pathways
-
Clarke, A.R., Purdie, C.A., Harrison, D.J., Morris, R.G., Bird, C.C., Hooper, M.L. and Wyllie, A.H. (1993) Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 362, 849-852.
-
(1993)
Nature
, vol.362
, pp. 849-852
-
-
Clarke, A.R.1
Purdie, C.A.2
Harrison, D.J.3
Morris, R.G.4
Bird, C.C.5
Hooper, M.L.6
Wyllie, A.H.7
-
96
-
-
0027319521
-
p53 is required for radiation-induced apoptosis in mouse thymocytes
-
Lowe, S.W., Schmitt, E.M., Smith, S.W., Osborne, B.A. and Jacks, T. (1993) p53 is required for radiation-induced apoptosis in mouse thymocytes. Nature, 362, 847-849.
-
(1993)
Nature
, vol.362
, pp. 847-849
-
-
Lowe, S.W.1
Schmitt, E.M.2
Smith, S.W.3
Osborne, B.A.4
Jacks, T.5
-
97
-
-
0029745387
-
Involvement of p53 in DNA strand break-induced apoptotis in postmitotic CNS neurons
-
Enokido, YI., Araki, T., Tanaka, K., Aizawa, S. and Hatanaka, H. (1996) Involvement of p53 in DNA strand break-induced apoptotis in postmitotic CNS neurons. Eur. Neurosci., 8, 1812-1821.
-
(1996)
Eur. Neurosci.
, vol.8
, pp. 1812-1821
-
-
Enokido, Y.I.1
Araki, T.2
Tanaka, K.3
Aizawa, S.4
Hatanaka, H.5
-
98
-
-
0029910961
-
Evidence for p53-mediated modulation of neuronal viability
-
Xiang, H., Hochman, D.W., Saya, H., Fujiwara, T., Schwartzkroin, P.A. and Morrison, R.S. (1996) Evidence for p53-mediated modulation of neuronal viability. J. Neurosci., 16, 6753-6765.
-
(1996)
J. Neurosci.
, vol.16
, pp. 6753-6765
-
-
Xiang, H.1
Hochman, D.W.2
Saya, H.3
Fujiwara, T.4
Schwartzkroin, P.A.5
Morrison, R.S.6
-
99
-
-
0029086989
-
The role of free radicals and p53 in neuron apoptosis in vivo
-
Wood, K.A. and Youle, R.J. (1995) The role of free radicals and p53 in neuron apoptosis in vivo. J. Neurosci., 15, 5851-5857.
-
(1995)
J. Neurosci.
, vol.15
, pp. 5851-5857
-
-
Wood, K.A.1
Youle, R.J.2
-
100
-
-
0030730292
-
Degeneration of neurons, synapses, and neuropils and glial activation in a murine Atm knockout model of ataxia-telangiectasia
-
Kuljis, R.O., Xu, Y., Aguila, M.C. and Baltimore, D. (1997) Degeneration of neurons, synapses, and neuropils and glial activation in a murine Atm knockout model of ataxia-telangiectasia. Proc. Natl Acad. Sci. USA, 94, 12688-12693.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12688-12693
-
-
Kuljis, R.O.1
Xu, Y.2
Aguila, M.C.3
Baltimore, D.4
-
101
-
-
0030808615
-
Cell-cycle regulation of mammalian DNA double-strand break repair
-
Hendrickson, E.A. (1997) Cell-cycle regulation of mammalian DNA double-strand break repair. Am. J. Hum. Genet., 61, 795-800.
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 795-800
-
-
Hendrickson, E.A.1
-
102
-
-
0030811585
-
Double indemnity: p53, BRCA and cancer
-
Brugarolas, J. and Jacks, T. (1997) Double indemnity: p53, BRCA and cancer. Nature Med., 7, 721-722.
-
(1997)
Nature Med.
, vol.7
, pp. 721-722
-
-
Brugarolas, J.1
Jacks, T.2
-
103
-
-
0032548827
-
BRCA1, BRCA2, and DNA damage response: Collision or collusion?
-
Zhang, H., Tombline, G. and Weber, B.L. (1998) BRCA1, BRCA2, and DNA damage response: collision or collusion? Cell, 92, 433-436.
-
(1998)
Cell
, vol.92
, pp. 433-436
-
-
Zhang, H.1
Tombline, G.2
Weber, B.L.3
-
104
-
-
0030659153
-
Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation
-
Connor, F., Bertwistle, D., Mee, P.J., Ross, G.M., Swift, S., Grigorieva, E., Tybulewicz, V.L.J. and Ashworth, A. (1997) Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation. Nature Genet., 17, 423-430.
-
(1997)
Nature Genet.
, vol.17
, pp. 423-430
-
-
Connor, F.1
Bertwistle, D.2
Mee, P.J.3
Ross, G.M.4
Swift, S.5
Grigorieva, E.6
Tybulewicz, V.L.J.7
Ashworth, A.8
-
105
-
-
0030698851
-
DNA-PKcs: A T-cell tumour suppressor encoded at the mouse scid locus
-
Jhappan, C., Morse, H.C. III, Fleishmann, R.D., Gottesman, M.M. and Merlino, G. (1997) DNA-PKcs: a T-cell tumour suppressor encoded at the mouse scid locus. Nature Genet., 17, 483-486.
-
(1997)
Nature Genet.
, vol.17
, pp. 483-486
-
-
Jhappan, C.1
Morse III, H.C.2
Fleishmann, R.D.3
Gottesman, M.M.4
Merlino, G.5
-
107
-
-
0030932869
-
Gatekeepers and caretakers
-
Kinzler, K.E. and Vogelstein, B. (1997) Gatekeepers and caretakers. Nature, 386, 761-763.
-
(1997)
Nature
, vol.386
, pp. 761-763
-
-
Kinzler, K.E.1
Vogelstein, B.2
-
108
-
-
16044364385
-
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis
-
Santana, P., Pena, L.A., Haimovitz-Friedman, A., Martin, S., Green, D., McLoughlin, M., Cordon-Cardo, C., Schuchman, E.H., Fukz, Z. and Kolesnick, R. (1996) Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis. Cell. 86, 189-199.
-
(1996)
Cell
, vol.86
, pp. 189-199
-
-
Santana, P.1
Pena, L.A.2
Haimovitz-Friedman, A.3
Martin, S.4
Green, D.5
McLoughlin, M.6
Cordon-Cardo, C.7
Schuchman, E.H.8
Fukz, Z.9
Kolesnick, R.10
-
109
-
-
0029021663
-
Discovery of at gene sparks biomedical research bonanza
-
Novak, R. (1995) Discovery of AT gene sparks biomedical research bonanza. Science, 268, 1700-1701.
-
(1995)
Science
, vol.268
, pp. 1700-1701
-
-
Novak, R.1
|