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Volumn 16, Issue 9, 1996, Pages 4952-4960

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P21; PROTEIN P53;

EID: 0029742781     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.9.4952     Document Type: Article
Times cited : (256)

References (56)
  • 1
    • 0028879323 scopus 로고
    • Regulation of p53-mediated apoptosis and cell cycle arrest by steel factor
    • Abrahamson, J. L. A., J. M. Lee, and A. Bernstein. 1995. Regulation of p53-mediated apoptosis and cell cycle arrest by steel factor. Mol. Cell. Biol. 15:6953-6960.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6953-6960
    • Abrahamson, J.L.A.1    Lee, J.M.2    Bernstein, A.3
  • 2
    • 0028882511 scopus 로고
    • DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective
    • Allday, M. J., G. J. Inman, D. H. Crawford, and P. J. Farrell. 1995. DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. EMBO J. 14:4994-5005.
    • (1995) EMBO J. , vol.14 , pp. 4994-5005
    • Allday, M.J.1    Inman, G.J.2    Crawford, D.H.3    Farrell, P.J.4
  • 3
    • 0025040233 scopus 로고
    • Suppression of human colorectal carcinoma cell growth by wild-type p53
    • Baker, S. J., S. Markowitz, E. R. Fearon, J. K. V. Willson, and B. Vogelstein. 1990. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249:912-915.
    • (1990) Science , vol.249 , pp. 912-915
    • Baker, S.J.1    Markowitz, S.2    Fearon, E.R.3    Willson, J.K.V.4    Vogelstein, B.5
  • 4
    • 0022483186 scopus 로고
    • Isolation of human p53 specific monoclonal antibodies and their use in the studies of human p53 expression
    • Banks, L., G. Matlashewski, and L. Crawford. 1986. Isolation of human p53 specific monoclonal antibodies and their use in the studies of human p53 expression. Eur. J. Biochem. 159:529-534.
    • (1986) Eur. J. Biochem. , vol.159 , pp. 529-534
    • Banks, L.1    Matlashewski, G.2    Crawford, L.3
  • 5
    • 0029670589 scopus 로고    scopus 로고
    • p53 in signalling checkpoint arrest or apoptosis
    • Bates, S., and K. H. Vousden. 1996. p53 in signalling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev. 6:1-7.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 1-7
    • Bates, S.1    Vousden, K.H.2
  • 8
    • 0028070989 scopus 로고
    • p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles, C., A. Helmberg, and M. Karin. 1994. p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes. Nature (London) 370:220-223.
    • (1994) Nature (London) , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 9
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman, C. E., T. M. Gilmer, S. B. Coutts, and M. B. Kastan. 1995. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes Dev. 9:600-611.
    • (1995) Genes Dev. , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Coutts, S.B.3    Kastan, M.B.4
  • 10
    • 0027203117 scopus 로고
    • Heterogeneity of transcriptional activity of mutant p53 protein and p53 DNA target sequences
    • Chen, J. Y., W. D. Funk, W. E. Wright, J. W. Shay, and J. D. Minna. 1993. Heterogeneity of transcriptional activity of mutant p53 protein and p53 DNA target sequences. Oncogene 8:2159-2166.
    • (1993) Oncogene , vol.8 , pp. 2159-2166
    • Chen, J.Y.1    Funk, W.D.2    Wright, W.E.3    Shay, J.W.4    Minna, J.D.5
  • 11
    • 0026731894 scopus 로고
    • Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents
    • Collins, M. K. L., J. Marvel, P. Malde, and A. Lopez-Rivas. 1992. Interleukin 3 protects murine bone marrow cells from apoptosis induced by DNA damaging agents. J. Exp. Med. 176:1043-1051.
    • (1992) J. Exp. Med. , vol.176 , pp. 1043-1051
    • Collins, M.K.L.1    Marvel, J.2    Malde, P.3    Lopez-Rivas, A.4
  • 12
    • 0028347587 scopus 로고
    • Modulation of transcriptional regulatory properties of p53 by HPV E6
    • Crook, T., C. Fisher, P. J. Masterson, and K. H. Vousden. 1994. Modulation of transcriptional regulatory properties of p53 by HPV E6. Oncogene 9:1225-1230.
    • (1994) Oncogene , vol.9 , pp. 1225-1230
    • Crook, T.1    Fisher, C.2    Masterson, P.J.3    Vousden, K.H.4
  • 13
    • 0029863303 scopus 로고    scopus 로고
    • Sensitivity of p53 lysine mutants to ubiquitin-directed degradation trageted by human papillimavirus E6
    • Crook, T., R. L. Ludwig, N. J. Marston, D. Willkomm, and K. H. Vousden. 1996. Sensitivity of p53 lysine mutants to ubiquitin-directed degradation trageted by human papillimavirus E6. Virology 217:285-292.
    • (1996) Virology , vol.217 , pp. 285-292
    • Crook, T.1    Ludwig, R.L.2    Marston, N.J.3    Willkomm, D.4    Vousden, K.H.5
  • 14
    • 0028131554 scopus 로고
    • Transcriptional activation by p53 correlates with suppression of growth but not transformation
    • Crook, T., N. J. Marston, E. A. Sara, and K. H. Vousden. 1994. Transcriptional activation by p53 correlates with suppression of growth but not transformation. Cell 79:817-827.
    • (1994) Cell , vol.79 , pp. 817-827
    • Crook, T.1    Marston, N.J.2    Sara, E.A.3    Vousden, K.H.4
  • 15
    • 0026660339 scopus 로고
    • Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens
    • Crook, T., and K. H. Vousden. 1992. Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens. EMBO J. 11:3935-3940.
    • (1992) EMBO J. , vol.11 , pp. 3935-3940
    • Crook, T.1    Vousden, K.H.2
  • 16
    • 0028325483 scopus 로고
    • Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7
    • Demers, G. W., S. A. Foster, C. L. Halbert, and D. A. Galloway. 1994. Growth arrest by induction of p53 in DNA damaged keratinocytes is bypassed by human papillomavirus 16 E7. Proc. Natl. Acad. Sci. USA 91:4382-4386.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 4382-4386
    • Demers, G.W.1    Foster, S.A.2    Halbert, C.L.3    Galloway, D.A.4
  • 17
    • 0028978183 scopus 로고
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 82:675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 20
    • 0028220204 scopus 로고
    • p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
    • Dulic, V., W. K. Kaufmann, S. J. Wilson, T. D. Tlsty, E. Lees, J. W. Harper, S. J. Elledge, and S. I. Reed. 1994. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell 76:1013-1023.
    • (1994) Cell , vol.76 , pp. 1013-1023
    • Dulic, V.1    Kaufmann, W.K.2    Wilson, S.J.3    Tlsty, T.D.4    Lees, E.5    Harper, J.W.6    Elledge, S.J.7    Reed, S.I.8
  • 23
    • 0030092024 scopus 로고    scopus 로고
    • Immunological analysis of Waf1/Cip1 protein expression in normal human tissues using a panel of novel monoclonal antibodies
    • Fredersdorf, S., A. W. Milne, P. A. Hall, and X. Lu. 1996. Immunological analysis of Waf1/Cip1 protein expression in normal human tissues using a panel of novel monoclonal antibodies. Am. J. Pathol. 148:825-835.
    • (1996) Am. J. Pathol. , vol.148 , pp. 825-835
    • Fredersdorf, S.1    Milne, A.W.2    Hall, P.A.3    Lu, X.4
  • 24
    • 0029783722 scopus 로고    scopus 로고
    • A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis
    • Friedlander, P., Y. Haupt, C. Prives, and M. Oren. 1996. A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis. Mol. Cell. Biol. 16:4961-4971.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4961-4971
    • Friedlander, P.1    Haupt, Y.2    Prives, C.3    Oren, M.4
  • 25
    • 0028294898 scopus 로고
    • Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3 dependent hematopoietic cells following IL-3 withdrawal
    • Gottlieb, E., R. Haffner, T. von Ruden, E. F. Wagner, and M. Oren. 1994. Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3 dependent hematopoietic cells following IL-3 withdrawal. EMBO J. 13: 1368-1374.
    • (1994) EMBO J. , vol.13 , pp. 1368-1374
    • Gottlieb, E.1    Haffner, R.2    Von Ruden, T.3    Wagner, E.F.4    Oren, M.5
  • 26
    • 0028263811 scopus 로고
    • c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington, E. A., M. R. Bennett, A. Fanidi, and G. I. Evan. 1994. c-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J. 13:3286-3295.
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 27
    • 0029985647 scopus 로고    scopus 로고
    • Cell type-specific inhibition of p53-mediated apoptosis by mdm2
    • Haupt, Y., Y. Barak, and M. Oren. 1996. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 15:1596-1606.
    • (1996) EMBO J. , vol.15 , pp. 1596-1606
    • Haupt, Y.1    Barak, Y.2    Oren, M.3
  • 28
    • 0028999429 scopus 로고
    • p53-mediated apoptosis in HeLa cells can be overcome by excess pRB
    • Haupt, Y., S. Rowan, and M. Oren. 1995. p53-mediated apoptosis in HeLa cells can be overcome by excess pRB. Oncogene 10:1563-1571.
    • (1995) Oncogene , vol.10 , pp. 1563-1571
    • Haupt, Y.1    Rowan, S.2    Oren, M.3
  • 29
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by trans-activation deficient p53
    • Haupt, Y., S. Rowan, E. Shaulian, K. H. Vousden, and M. Oren. 1995. Induction of apoptosis in HeLa cells by trans-activation deficient p53. Genes Dev. 9:2170-2183.
    • (1995) Genes Dev. , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 30
    • 0028239976 scopus 로고
    • Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation
    • Hickman, E. S., S. M. Picksley, and K. H. Vousden. 1994. Cells expressing HPV16 E7 continue cell cycle progression following DNA damage induced p53 activation. Oncogene 9:2177-2181.
    • (1994) Oncogene , vol.9 , pp. 2177-2181
    • Hickman, E.S.1    Picksley, S.M.2    Vousden, K.H.3
  • 32
    • 0026448672 scopus 로고
    • Regulation of the specific DNA binding function of p53
    • Hupp, T. R., D. W. Meek, C. A. Midgley, and D. P. Lane. 1992. Regulation of the specific DNA binding function of p53. Cell 71:875-886.
    • (1992) Cell , vol.71 , pp. 875-886
    • Hupp, T.R.1    Meek, D.W.2    Midgley, C.A.3    Lane, D.P.4
  • 34
    • 0028821895 scopus 로고
    • Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle and apoptosis
    • Katayose, D., R. Wersto, K. H. Cowan, and P. Seth. 1995. Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle and apoptosis. Cell Growth Differ 6:1207-1212.
    • (1995) Cell Growth Differ , vol.6 , pp. 1207-1212
    • Katayose, D.1    Wersto, R.2    Cowan, K.H.3    Seth, P.4
  • 36
    • 0029416970 scopus 로고
    • Activation of p21WAF1/Cip1 expression by a temperature-sensitive mutant of human p53 does not lead to apoptosis
    • Kobayashi, T., U. Consoli, M. Andreeff, H. Shiku, A. B. Deisseroth, and W. Zhang. 1995. Activation of p21WAF1/Cip1 expression by a temperature-sensitive mutant of human p53 does not lead to apoptosis. Oncogene 11: 2311-2316.
    • (1995) Oncogene , vol.11 , pp. 2311-2316
    • Kobayashi, T.1    Consoli, U.2    Andreeff, M.3    Shiku, H.4    Deisseroth, A.B.5    Zhang, W.6
  • 37
    • 0027316813 scopus 로고
    • An E2F-binding site mediates cell-cycle regulation repression of mouse B-myb transcription
    • Lam, E. W. F., and R. J. Waston. 1993. An E2F-binding site mediates cell-cycle regulation repression of mouse B-myb transcription. EMBO J. 12:2705-2713.
    • (1993) EMBO J. , vol.12 , pp. 2705-2713
    • Lam, E.W.F.1    Waston, R.J.2
  • 38
    • 0028303752 scopus 로고
    • Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein
    • Lin, J., J. Chen, B. Elenbaas, and A. J. Levine. 1994. Several hydrophobic amino acids in the p53 amino-terminal domain are required for transcriptional activation, binding to mdm-2 and the adenovirus 5 E1B 55-kD protein. Genes Dev. 8:1235-1246.
    • (1994) Genes Dev. , vol.8 , pp. 1235-1246
    • Lin, J.1    Chen, J.2    Elenbaas, B.3    Levine, A.J.4
  • 41
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita, T., and J. C. Reed. 1995. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80:293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 44
    • 0030021748 scopus 로고    scopus 로고
    • Specific loss of apoptotic but not cell cycle arrest function in a human tumour derived p53 mutant
    • Rowan, S., R. L. Ludwig, Y. Haupt, S. Bates, X. Lu, M. Oren, and K. H. Vousden. 1996. Specific loss of apoptotic but not cell cycle arrest function in a human tumour derived p53 mutant. EMBO J. 15:827-838.
    • (1996) EMBO J. , vol.15 , pp. 827-838
    • Rowan, S.1    Ludwig, R.L.2    Haupt, Y.3    Bates, S.4    Lu, X.5    Oren, M.6    Vousden, K.H.7
  • 45
    • 0029143395 scopus 로고
    • Essential role for p53-mediated transcription in E1A-induced apoptosis
    • Sabbatini, P., J. Lin, A. J. Levine, and E. White. 1995. Essential role for p53-mediated transcription in E1A-induced apoptosis. Genes Dev. 9:2184-2192.
    • (1995) Genes Dev. , vol.9 , pp. 2184-2192
    • Sabbatini, P.1    Lin, J.2    Levine, A.J.3    White, E.4
  • 47
    • 0025375355 scopus 로고
    • Structural aspects of the p53 protein in relation to gene evolution
    • Soussi, T., C. Caron de Fromentel, and P. May. 1990. Structural aspects of the p53 protein in relation to gene evolution. Oncogene 5:945-952.
    • (1990) Oncogene , vol.5 , pp. 945-952
    • Soussi, T.1    Caron De Fromentel, C.2    May, P.3
  • 48
    • 0025648762 scopus 로고
    • Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome
    • Srivastava, S., Z. Zou, K. Pirollo, W. Blattner, and E. H. Chang. 1990. Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome. Nature (London) 348:747-749.
    • (1990) Nature (London) , vol.348 , pp. 747-749
    • Srivastava, S.1    Zou, Z.2    Pirollo, K.3    Blattner, W.4    Chang, E.H.5
  • 50
    • 0026769713 scopus 로고
    • An immunochemical analysis of the human nuclear phosphoprotein p53
    • Vojtesek, B., J. Bartek, C. A. Midgley, and D. P. Lane. 1992. An immunochemical analysis of the human nuclear phosphoprotein p53. J. Immunol. Methods 151:237-244.
    • (1992) J. Immunol. Methods , vol.151 , pp. 237-244
    • Vojtesek, B.1    Bartek, J.2    Midgley, C.A.3    Lane, D.P.4
  • 52
    • 0028849274 scopus 로고
    • p21 in necessary for the p53-mediated G1 arrest in human cancer cells
    • Waldman, T., K. W. Kinzler, and B. Vogelstein. 1995. p21 in necessary for the p53-mediated G1 arrest in human cancer cells. Cancer Res. 55:5187-5190.
    • (1995) Cancer Res. , vol.55 , pp. 5187-5190
    • Waldman, T.1    Kinzler, K.W.2    Vogelstein, B.3
  • 53
    • 0029003061 scopus 로고
    • Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases
    • Wang, Y., and C. Prives. 1995. Increased and altered DNA binding of human p53 by S and G2/M but not G1 cyclin-dependent kinases. Nature (London) 376:88-91.
    • (1995) Nature (London) , vol.376 , pp. 88-91
    • Wang, Y.1    Prives, C.2
  • 55
    • 0029585933 scopus 로고    scopus 로고
    • Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53
    • Yonish-Rouach, E., V. Deguin, T. Zaitchouk, C. Breugnot, Z. Mishal, J. R. Jenkins, and E. May. 1996. Transcriptional activation plays a role in the induction of apoptosis by transiently transfected wild-type p53. Oncogene 12:2197-2205.
    • (1996) Oncogene , vol.12 , pp. 2197-2205
    • Yonish-Rouach, E.1    Deguin, V.2    Zaitchouk, T.3    Breugnot, C.4    Mishal, Z.5    Jenkins, J.R.6    May, E.7
  • 56
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E., D. Resnitzky, J. Lotem, L. Sachs, A. Kimchi, and M. Oren. 1991. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (London) 353:345-347.
    • (1991) Nature (London) , vol.353 , pp. 345-347
    • Yonish-Rouach, E.1    Resnitzky, D.2    Lotem, J.3    Sachs, L.4    Kimchi, A.5    Oren, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.