bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 6, 1997, Pages 2345-2349

  Mccurrach, Mila E ^a   Connor, Thomas M F ^a   Knudson, C Michael ^b   Korsmeyer, Stanley J ^b   Lowe, Scott W ^a  

^a Watson School of Biological Sciences   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CHEMOSENSITIVITY; DRUG RESISTANCE; EMBRYO; EMBRYO CELL; FIBROBLAST; GENE EXPRESSION REGULATION; GROWTH STIMULATION; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CISPLATIN; CROSSES, GENETIC; DOXORUBICIN; DRUG RESISTANCE; EMBRYO; ETOPOSIDE; FIBROBLASTS; GENES, P53; MICE; MICE, KNOCKOUT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECOMBINATION, GENETIC; RNA, MESSENGER; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0030938089     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.6.2345     Document Type: Article

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