The requirement for the p53 proline-rich functional domain for mediation of apoptosis is correlated with specific PIG3 gene transactivation and with transcriptional repression

EMBO Journal

Volumn 17, Issue 16, 1998, Pages 4668-4679

  Venot, Corinne ^a   Maratrat, Michel ^a   Dureuil, Christine ^a   Conseiller, Emmanuel ^a   Bracco, Laurent ^a   Debussche, Laurent ^a  

^a SANOFI   (France)

Author keywords

Apoptosis; p53; PXXP motif; Repression; Sequence specific transactivation

Indexed keywords

PROLINE; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CELL CYCLE; CONTROLLED STUDY; DELETION MUTANT; DNA TRANSFECTION; GENE DELETION; GENE FUNCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DOMAIN; TATA BOX; TRANSACTIVATION; TRANSCRIPTION REGULATION; TUMOR SUPPRESSOR GENE;

ANTIBODIES, MONOCLONAL; APOPTOSIS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA PRIMERS; DNA-BINDING PROTEINS; HUMANS; NUCLEAR PROTEINS; PROLINE; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; PROTO-ONCOGENE PROTEINS C-MDM2; REACTIVE OXYGEN SPECIES; REPRESSOR PROTEINS; SEQUENCE DELETION; TATA BOX; TRANS-ACTIVATION (GENETICS); TUMOR SUPPRESSOR PROTEIN P53;

EID: 0032541325     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.16.4668     Document Type: Article

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