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Volumn 47, Issue 10, 2018, Pages 277-289

Model organism data evolving in support of translational medicine

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL MODEL; DATA BASE; EXPERIMENTAL ANIMAL; PROCEDURES; TRANSLATIONAL RESEARCH;

EID: 85053665993     PISSN: 00937355     EISSN: 15484475     Source Type: Journal    
DOI: 10.1038/s41684-018-0150-4     Document Type: Article
Times cited : (32)

References (195)
  • 1
    • 84884227319 scopus 로고    scopus 로고
    • A brief history of animal modeling
    • PID: 23829102
    • Ericsson, A. C., Crim, M. J. & Franklin, C. L. A brief history of animal modeling. Mo. Med. 110, 201–205 (2013).
    • (2013) Mo. Med. , vol.110 , pp. 201-205
    • Ericsson, A.C.1    Crim, M.J.2    Franklin, C.L.3
  • 2
    • 85039776073 scopus 로고    scopus 로고
    • Sophisticated lessons from simple organisms: appreciating the value of curiosity-driven research
    • PID: 29259023
    • Duronio, R. J., O’Farrell, P. H., Sluder, G. & Su, T. T. Sophisticated lessons from simple organisms: appreciating the value of curiosity-driven research. Dis. Model. Mech. 10, 1381–1389 (2017).
    • (2017) Dis. Model. Mech. , vol.10 , pp. 1381-1389
    • Duronio, R.J.1    O’Farrell, P.H.2    Sluder, G.3    Su, T.T.4
  • 3
    • 0000943490 scopus 로고
    • The progress of physiology
    • COI: 1:STN:280:DC%2BC3cvms1ertg%3D%3D, PID: 17732865
    • Krogh, A. The progress of physiology. Science 70, 200–204 (1929).
    • (1929) Science , vol.70 , pp. 200-204
    • Krogh, A.1
  • 4
    • 85042528949 scopus 로고    scopus 로고
    • The 2018 Nucleic Acids Research database issue and the online molecular biology database collection
    • PID: 29316735
    • Rigden, D. J. & Fernández, X. M. The 2018 Nucleic Acids Research database issue and the online molecular biology database collection. Nucleic Acids Res. 46(D1), D1–D7 (2018).
    • (2018) Nucleic Acids Res. , vol.46 , Issue.D1 , pp. D1-D7
    • Rigden, D.J.1    Fernández, X.M.2
  • 5
    • 84946735654 scopus 로고    scopus 로고
    • Gene Ontology Consortium: going forward
    • COI: 1:CAS:528:DC%2BC2sXhtVymtLvE
    • Gene Ontology Consortium. Gene Ontology Consortium: going forward. Nucleic Acids Res. 43, D1049–D1056 (2015).
    • (2015) Nucleic Acids Res. , vol.43 , pp. D1049-D1056
  • 6
    • 75949096070 scopus 로고    scopus 로고
    • Donlin, M. J. Using the Generic Genome Browser (GBrowse). Curr. Protoc. Bioinforma
    • Donlin, M. J. Using the Generic Genome Browser (GBrowse). Curr. Protoc. Bioinforma. Chapter 9, Unit 9.9 (2009).
    • (2009) Chapter 9, Unit , vol.9 , pp. 9
  • 7
    • 85020652497 scopus 로고    scopus 로고
    • Building dialogues between clinical and biomedical research through cross-species collaborations
    • PID: 28579453
    • Chao, H.-T., Liu, L. & Bellen, H. J. Building dialogues between clinical and biomedical research through cross-species collaborations. Semin. Cell Dev. Biol. 70, 49–57 (2017).
    • (2017) Semin. Cell Dev. Biol. , vol.70 , pp. 49-57
    • Chao, H.T.1    Liu, L.2    Bellen, H.J.3
  • 8
    • 85029005115 scopus 로고    scopus 로고
    • Model organisms facilitate rare disease diagnosis and therapeutic research
    • PID: 28874452
    • Wangler, M. F. et al. Model organisms facilitate rare disease diagnosis and therapeutic research. Genetics 207, 9–27 (2017).
    • (2017) Genetics , vol.207 , pp. 9-27
    • Wangler, M.F.1
  • 9
    • 85016023655 scopus 로고    scopus 로고
    • Bedside back to bench: building bridges between basic and clinical genomic research
    • COI: 1:CAS:528:DC%2BC2sXltVWns7s%3D, PID: 28340351
    • Manolio, T. A. et al. Bedside back to bench: building bridges between basic and clinical genomic research. Cell 169, 6–12 (2017).
    • (2017) Cell , vol.169 , pp. 6-12
    • Manolio, T.A.1
  • 10
    • 84978055812 scopus 로고    scopus 로고
    • Model organism databases: essential resources that need the support of both funders and users
    • COI: 1:CAS:528:DC%2BC2sXnvVWls7c%3D, PID: 27334346
    • Oliver, S. G., Lock, A., Harris, M. A., Nurse, P. & Wood, V. Model organism databases: essential resources that need the support of both funders and users. BMC Biol. 14, 49 (2016).
    • (2016) BMC Biol. , vol.14
    • Oliver, S.G.1    Lock, A.2    Harris, M.A.3    Nurse, P.4    Wood, V.5
  • 11
    • 85040320219 scopus 로고    scopus 로고
    • On expert curation and scalability: UniProtKB/Swiss-Prot as a case study
    • PID: 29036270
    • Poux, S. et al. On expert curation and scalability: UniProtKB/Swiss-Prot as a case study. Bioinformatics 33, 3454–3460 (2017).
    • (2017) Bioinformatics , vol.33 , pp. 3454-3460
    • Poux, S.1
  • 12
    • 85016026174 scopus 로고    scopus 로고
    • FlyBase at 25: looking to the future
    • COI: 1:CAS:528:DC%2BC1cXhsVKrtL0%3D, PID: 27799470
    • Gramates, L. S. et al. FlyBase at 25: looking to the future. Nucleic Acids Res. 45(D1), D663–D671 (2017).
    • (2017) Nucleic Acids Res. , vol.45 , Issue.D1 , pp. D663-D671
    • Gramates, L.S.1
  • 13
    • 84924985583 scopus 로고    scopus 로고
    • Fruit flies in biomedical research
    • COI: 1:CAS:528:DC%2BC2MXlsFSksrs%3D, PID: 25624315
    • Wangler, M. F., Yamamoto, S. & Bellen, H. J. Fruit flies in biomedical research. Genetics 199, 639–653 (2015).
    • (2015) Genetics , vol.199 , pp. 639-653
    • Wangler, M.F.1    Yamamoto, S.2    Bellen, H.J.3
  • 14
    • 0019945644 scopus 로고
    • Genetic transformation of Drosophila with transposable element vectors
    • COI: 1:CAS:528:DyaL3sXhtFOj, PID: 6289436
    • Rubin, G. M. & Spradling, A. C. Genetic transformation of Drosophila with transposable element vectors. Science 218, 348–353 (1982).
    • (1982) Science , vol.218 , pp. 348-353
    • Rubin, G.M.1    Spradling, A.C.2
  • 15
    • 0032883802 scopus 로고    scopus 로고
    • The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes
    • COI: 1:CAS:528:DyaK1MXmsVWqtLs%3D, PID: 10471706
    • Spradling, A. C. et al. The Berkeley Drosophila Genome Project gene disruption project: single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153, 135–177 (1999).
    • (1999) Genetics , vol.153 , pp. 135-177
    • Spradling, A.C.1
  • 16
    • 79960114353 scopus 로고    scopus 로고
    • The Drosophila gene disruption project: progress using transposons with distinctive site specificities
    • COI: 1:CAS:528:DC%2BC3MXhtVGksrfE, PID: 21515576
    • Bellen, H. J. et al. The Drosophila gene disruption project: progress using transposons with distinctive site specificities. Genetics 188, 731–743 (2011).
    • (2011) Genetics , vol.188 , pp. 731-743
    • Bellen, H.J.1
  • 17
    • 84961738526 scopus 로고    scopus 로고
    • Fruit flies on the front line: the translational impact of Drosophila
    • COI: 1:CAS:528:DC%2BC2sXmtVKms7Y%3D, PID: 26935101
    • Perrimon, N., Bonini, N. M. & Dhillon, P. Fruit flies on the front line: the translational impact of Drosophila. Dis. Model. Mech. 9, 229–231 (2016).
    • (2016) Dis. Model. Mech. , vol.9 , pp. 229-231
    • Perrimon, N.1    Bonini, N.M.2    Dhillon, P.3
  • 18
    • 85021985283 scopus 로고    scopus 로고
    • Taking stock of the Drosophila research ecosystem
    • PID: 28684603
    • Bilder, D. & Irvine, K. D. Taking stock of the Drosophila research ecosystem. Genetics 206, 1227–1236 (2017).
    • (2017) Genetics , vol.206 , pp. 1227-1236
    • Bilder, D.1    Irvine, K.D.2
  • 19
    • 85020639941 scopus 로고    scopus 로고
    • A short history and description of Drosophila melanogaster classical genetics: chromosome aberrations, forward genetic screens, and the nature of mutations
    • PID: 28592503
    • Kaufman, T. C. A short history and description of Drosophila melanogaster classical genetics: chromosome aberrations, forward genetic screens, and the nature of mutations. Genetics 206, 665–689 (2017).
    • (2017) Genetics , vol.206 , pp. 665-689
    • Kaufman, T.C.1
  • 20
    • 85030720345 scopus 로고    scopus 로고
    • & Schnorrer, F. Gene tagging strategies to assess protein expression, localization, and function in Drosophila
    • PID: 5629313
    • Kanca, O. & Bellen, H. J. & Schnorrer, F. Gene tagging strategies to assess protein expression, localization, and function in Drosophila. Genetics 207, 389–412 (2017).
    • (2017) Genetics , vol.207 , pp. 389-412
    • Kanca, O.1    Bellen, H.J.2
  • 21
    • 85040129921 scopus 로고    scopus 로고
    • Advances in engineering the fly genome with the CRISPR–Cas system
    • Bier, E., Harrison, M. M., O’Connor-Giles, K. M. & Wildonger, J. Advances in engineering the fly genome with the CRISPR–Cas system. Genetics 208, 1–18 (2018).
    • (2018) Genetics , vol.208 , pp. 1-18
    • Bier, E.1    Harrison, M.M.2    O’Connor-Giles, K.M.3    Wildonger, J.4
  • 23
    • 18044380762 scopus 로고    scopus 로고
    • humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila
    • COI: 1:CAS:528:DC%2BD2MXjsFKhsr8%3D
    • Bandura, J. L. et al. humpty dumpty is required for developmental DNA amplification and cell proliferation in Drosophila. Curr. Biol. 15, 755–759 (2005).
    • (2005) Curr. Biol. , vol.15 , pp. 755-759
    • Bandura, J.L.1
  • 24
    • 85026643052 scopus 로고    scopus 로고
    • Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly–micromelia syndrome
    • COI: 1:CAS:528:DC%2BC2sXhtl2htrrO, PID: 5538549
    • Evrony, G. D. et al. Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly–micromelia syndrome. Genome Res. 27, 1323–1335 (2017).
    • (2017) Genome Res. , vol.27 , pp. 1323-1335
    • Evrony, G.D.1
  • 25
    • 85032986485 scopus 로고    scopus 로고
    • Rapid DNA synthesis during early Drosophila embryogenesis is sensitive to maternal Humpty Dumpty protein function
    • Lesly, S., Bandura, J. L. & Calvi, B. R. Rapid DNA synthesis during early Drosophila embryogenesis is sensitive to maternal Humpty Dumpty protein function. Genetics 207, 935–947 (2017).
    • (2017) Genetics , vol.207 , pp. 935-947
    • Lesly, S.1    Bandura, J.L.2    Calvi, B.R.3
  • 26
    • 85012247268 scopus 로고    scopus 로고
    • Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
    • COI: 1:CAS:528:DC%2BC2sXitlGiu7g%3D, PID: 5450907
    • Reynolds, J. J. et al. Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism. Nat. Genet. 49, 537–549 (2017).
    • (2017) Nat. Genet. , vol.49 , pp. 537-549
    • Reynolds, J.J.1
  • 27
    • 18144392678 scopus 로고    scopus 로고
    • ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma
    • COI: 1:CAS:528:DC%2BD2MXjslGltbk%3D
    • Vidal, M., Wells, S., Ryan, A. & Cagan, R. ZD6474 suppresses oncogenic RET isoforms in a Drosophila model for type 2 multiple endocrine neoplasia syndromes and papillary thyroid carcinoma. Cancer Res. 65, 3538–3541 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 3538-3541
    • Vidal, M.1    Wells, S.2    Ryan, A.3    Cagan, R.4
  • 28
    • 84861943484 scopus 로고    scopus 로고
    • Chemical genetic discovery of targets and anti-targets for cancer polypharmacology
    • COI: 1:CAS:528:DC%2BC38Xot1Cnu7w%3D, PID: 22678283
    • Dar, A. C., Das, T. K., Shokat, K. M. & Cagan, R. L. Chemical genetic discovery of targets and anti-targets for cancer polypharmacology. Nature 486, 80–84 (2012).
    • (2012) Nature , vol.486 , pp. 80-84
    • Dar, A.C.1    Das, T.K.2    Shokat, K.M.3    Cagan, R.L.4
  • 29
    • 84961755109 scopus 로고    scopus 로고
    • FlyBase portals to human disease research using Drosophila models
    • COI: 1:CAS:528:DC%2BC2sXmtVKmsbc%3D, PID: 26935103
    • Millburn, G. H., Crosby, M. A., Gramates, L. S. & Tweedie, S. FlyBase portals to human disease research using Drosophila models. Dis. Model. Mech. 9, 245–252 (2016).
    • (2016) Dis. Model. Mech. , vol.9 , pp. 245-252
    • Millburn, G.H.1    Crosby, M.A.2    Gramates, L.S.3    Tweedie, S.4
  • 30
    • 85027251911 scopus 로고    scopus 로고
    • Gene2Function: an integrated online resource for gene function discovery
    • &
    • Hu, Y., Comjean, A., Mohr, S.E. & Perrimon, N. Gene2Function: an integrated online resource for gene function discovery. G3 7, 2855–2858 (2017).
    • (2017) G3 , vol.3-7 , pp. 2855-2858
    • Hu, Y.1    Comjean, A.2    Mohr, S.E.3    Perrimon, N.4
  • 31
    • 85040939083 scopus 로고    scopus 로고
    • Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data
    • PID: 29155944
    • Hu, Y. et al. Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data. Nucleic Acids Res. 46(D1), D567–D574 (2018).
    • (2018) Nucleic Acids Res. , vol.46 , Issue.D1 , pp. D567-D574
    • Hu, Y.1
  • 32
    • 85019064193 scopus 로고    scopus 로고
    • MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome
    • COI: 1:CAS:528:DC%2BC2sXns1yiu7c%3D, PID: 28502612
    • Wang, J. et al. MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome. Am. J. Hum. Genet. 100, 843–853 (2017).
    • (2017) Am. J. Hum. Genet. , vol.100 , pp. 843-853
    • Wang, J.1
  • 33
    • 0030754904 scopus 로고    scopus 로고
    • FlyBase: a Drosophila database. The FlyBase consortium
    • COI: 1:STN:280:DyaK2s7ovValtg%3D%3D, PID: 9045212
    • Gelbart, W. M. et al. FlyBase: a Drosophila database. The FlyBase consortium. Nucleic Acids Res. 25, 63–66 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 63-66
    • Gelbart, W.M.1
  • 34
    • 80052851950 scopus 로고    scopus 로고
    • Mouse genomic variation and its effect on phenotypes and gene regulation
    • COI: 1:CAS:528:DC%2BC3MXhtFOlsL7N, PID: 21921910
    • Keane, T. M. et al. Mouse genomic variation and its effect on phenotypes and gene regulation. Nature 477, 289–294 (2011).
    • (2011) Nature , vol.477 , pp. 289-294
    • Keane, T.M.1
  • 35
    • 33846002394 scopus 로고    scopus 로고
    • A mouse for all reasons
    • COI: 1:CAS:528:DC%2BD2sXptl2itg%3D%3D
    • International Mouse Knockout Consortium. A mouse for all reasons. Cell 128, 9–13 (2007).
    • (2007) Cell , vol.128 , pp. 9-13
  • 36
    • 84867332476 scopus 로고    scopus 로고
    • The mammalian gene function resource: the International Knockout Mouse Consortium
    • PID: 22968824
    • Bradley, A. et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm. Genome 23, 580–586 (2012).
    • (2012) Mamm. Genome , vol.23 , pp. 580-586
    • Bradley, A.1
  • 37
    • 84867337003 scopus 로고    scopus 로고
    • The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping
    • COI: 1:CAS:528:DC%2BC38XhsVKrt77M, PID: 22940749
    • Brown, S. D. M. & Moore, M. W. The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping. Mamm. Genome 23, 632–640 (2012).
    • (2012) Mamm. Genome , vol.23 , pp. 632-640
    • Brown, S.D.M.1    Moore, M.W.2
  • 38
    • 84863115856 scopus 로고    scopus 로고
    • The genome architecture of the Collaborative Cross mouse genetic reference population
    • COI: 1:CAS:528:DC%2BC38XnsVSmsbg%3D, PID: 3276630
    • Collaborative Cross Consortium. The genome architecture of the Collaborative Cross mouse genetic reference population. Genetics 190, 389–401 (2012).
    • (2012) Genetics , vol.190 , pp. 389-401
  • 39
    • 84865180612 scopus 로고    scopus 로고
    • Ten years of the collaborative cross
    • &
    • Threadgill, D.W. & Churchill, G.A. Ten years of the collaborative cross. G3 2, 153–156 (2012).
    • (2012) G3 , vol.2-3 , pp. 153-156
    • Threadgill, D.W.1    Churchill, G.A.2
  • 41
    • 84857410370 scopus 로고    scopus 로고
    • High-resolution genetic mapping using the Mouse Diversity outbred population
    • COI: 1:CAS:528:DC%2BC38XnsVSmsbY%3D, PID: 22345611
    • Svenson, K. L. et al. High-resolution genetic mapping using the Mouse Diversity outbred population. Genetics 190, 437–447 (2012).
    • (2012) Genetics , vol.190 , pp. 437-447
    • Svenson, K.L.1
  • 42
    • 80051562374 scopus 로고    scopus 로고
    • Genetic analysis in the Collaborative Cross breeding population
    • COI: 1:CAS:528:DC%2BC3MXpvFeqs78%3D, PID: 21734011
    • Philip, V. M. et al. Genetic analysis in the Collaborative Cross breeding population. Genome Res. 21, 1223–1238 (2011).
    • (2011) Genome Res. , vol.21 , pp. 1223-1238
    • Philip, V.M.1
  • 43
    • 84878649483 scopus 로고    scopus 로고
    • High-precision genetic mapping of behavioral traits in the diversity outbred mouse population
    • COI: 1:CAS:528:DC%2BC3sXhtVOkurbP, PID: 23433259
    • Logan, R. W. et al. High-precision genetic mapping of behavioral traits in the diversity outbred mouse population. Genes Brain Behav. 12, 424–437 (2013).
    • (2013) Genes Brain Behav. , vol.12 , pp. 424-437
    • Logan, R.W.1
  • 44
    • 84895866508 scopus 로고    scopus 로고
    • Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research
    • PID: 24272351
    • Chesler, E. J. Out of the bottleneck: the Diversity Outcross and Collaborative Cross mouse populations in behavioral genetics research. Mamm. Genome 25, 3–11 (2014).
    • (2014) Mamm. Genome , vol.25 , pp. 3-11
    • Chesler, E.J.1
  • 45
    • 79958134728 scopus 로고    scopus 로고
    • Mouse models of cystic fibrosis: phenotypic analysis and research applications
    • COI: 1:CAS:528:DC%2BC3MXpsVGisr0%3D, PID: 21658634
    • Wilke, M. et al. Mouse models of cystic fibrosis: phenotypic analysis and research applications. J. Cyst. Fibros. 10(Suppl. 2), S152–S171 (2011).
    • (2011) J. Cyst. Fibros. , vol.10 , pp. S152-S171
    • Wilke, M.1
  • 46
    • 17144397614 scopus 로고    scopus 로고
    • A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse
    • COI: 1:CAS:528:DC%2BD2MXivV2rsbc%3D, PID: 15722353
    • Tsuji, T. & Kunieda, T. A loss-of-function mutation in natriuretic peptide receptor 2 (Npr2) gene is responsible for disproportionate dwarfism in cn/cn mouse. J. Biol. Chem. 280, 14288–14292 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 14288-14292
    • Tsuji, T.1    Kunieda, T.2
  • 47
    • 85016288977 scopus 로고    scopus 로고
    • Severity of demyelinating and axonal neuropathy mouse models is modified by genes affecting structure and function of peripheral nodes
    • COI: 1:CAS:528:DC%2BC2sXlt12ru7w%3D, PID: 28355569
    • Morelli, K. H. et al. Severity of demyelinating and axonal neuropathy mouse models is modified by genes affecting structure and function of peripheral nodes. Cell Rep. 18, 3178–3191 (2017).
    • (2017) Cell Rep. , vol.18 , pp. 3178-3191
    • Morelli, K.H.1
  • 48
    • 84976340668 scopus 로고    scopus 로고
    • CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa
    • COI: 1:CAS:528:DC%2BC28XhtVOnsrfI, PID: 27203441
    • Wu, W.-H. et al. CRISPR repair reveals causative mutation in a preclinical model of retinitis pigmentosa. Mol. Ther. 24, 1388–1394 (2016).
    • (2016) Mol. Ther. , vol.24 , pp. 1388-1394
    • Wu, W.H.1
  • 49
    • 85036568063 scopus 로고    scopus 로고
    • Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality
    • COI: 1:CAS:528:DC%2BC1cXhtlCjtrjO, PID: 29079688
    • Metzger, M. W. et al. Heterozygosity for the mood disorder-associated variant Gln460Arg alters P2X7 receptor function and sleep quality. J. Neurosci. 37, 11688–11700 (2017).
    • (2017) J. Neurosci. , vol.37 , pp. 11688-11700
    • Metzger, M.W.1
  • 50
    • 85042616653 scopus 로고    scopus 로고
    • Therapeutic genome editing with CRISPR/Cas9 in a humanized mouse model ameliorates α1-antitrypsin deficiency phenotype
    • PID: 29500128
    • Bjursell, M. et al. Therapeutic genome editing with CRISPR/Cas9 in a humanized mouse model ameliorates α1-antitrypsin deficiency phenotype. EBioMedicine 29, 104–111 (2018).
    • (2018) EBioMedicine , vol.29 , pp. 104-111
    • Bjursell, M.1
  • 51
    • 84873734105 scopus 로고    scopus 로고
    • RNA-guided human genome engineering via Cas9
    • COI: 1:CAS:528:DC%2BC3sXit1ygtb0%3D, PID: 23287722
    • Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823–826 (2013).
    • (2013) Science , vol.339 , pp. 823-826
    • Mali, P.1
  • 52
    • 84877707375 scopus 로고    scopus 로고
    • One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
    • COI: 1:CAS:528:DC%2BC3sXmvF2nt7w%3D, PID: 23643243
    • Wang, H. et al. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910–918 (2013).
    • (2013) Cell , vol.153 , pp. 910-918
    • Wang, H.1
  • 53
    • 85035097486 scopus 로고    scopus 로고
    • Genome editing for the reproduction and remedy of human diseases in mice
    • COI: 1:CAS:528:DC%2BC1cXjtVeqsb8%3D, PID: 29180644
    • Hara, S. & Takada, S. Genome editing for the reproduction and remedy of human diseases in mice. J. Hum. Genet. 63, 107–113 (2018).
    • (2018) J. Hum. Genet. , vol.63 , pp. 107-113
    • Hara, S.1    Takada, S.2
  • 54
    • 85020851159 scopus 로고    scopus 로고
    • Modelling autistic features in mice using quantitative genetic approaches
    • PID: 28551751
    • Molenhuis, R. T., Bruining, H. & Kas, M. J. Modelling autistic features in mice using quantitative genetic approaches. Adv. Anat. Embryol. Cell Biol. 224, 65–84 (2017).
    • (2017) Adv. Anat. Embryol. Cell Biol. , vol.224 , pp. 65-84
    • Molenhuis, R.T.1    Bruining, H.2    Kas, M.J.3
  • 55
    • 85040948809 scopus 로고    scopus 로고
    • Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism
    • St Clair, D. & Johnstone, M. Using mouse transgenic and human stem cell technologies to model genetic mutations associated with schizophrenia and autism. Phil. Trans. R. Soc. Lond. B 373, 20170037 (2018).
    • (2018) Phil. Trans. R. Soc. Lond. B , vol.373 , pp. 20170037
    • St Clair, D.1    Johnstone, M.2
  • 56
    • 85009973169 scopus 로고    scopus 로고
    • How mice are indispensable for understanding obesity and diabetes genetics
    • PID: 28107248
    • Attie, A. D., Churchill, G. A. & Nadeau, J. H. How mice are indispensable for understanding obesity and diabetes genetics. Curr. Opin. Endocrinol. Diabetes Obes. 24, 83–91 (2017).
    • (2017) Curr. Opin. Endocrinol. Diabetes Obes. , vol.24 , pp. 83-91
    • Attie, A.D.1    Churchill, G.A.2    Nadeau, J.H.3
  • 57
    • 85043355488 scopus 로고    scopus 로고
    • A Hitchhiker’s guide to humanized mice: new pathways to studying viral infections
    • COI: 1:CAS:528:DC%2BC1cXktVKksLw%3D, PID: 29446074
    • Skelton, J. K., Ortega-Prieto, A. M. & Dorner, M. A Hitchhiker’s guide to humanized mice: new pathways to studying viral infections. Immunology 154, 50–61 (2018).
    • (2018) Immunology , vol.154 , pp. 50-61
    • Skelton, J.K.1    Ortega-Prieto, A.M.2    Dorner, M.3
  • 58
    • 85037036565 scopus 로고    scopus 로고
    • A novel human systemic lupus erythematosus model in humanised mice
    • COI: 1:CAS:528:DC%2BC1cXhsFWnsrfN, PID: 29192160
    • Gunawan, M. et al. A novel human systemic lupus erythematosus model in humanised mice. Sci. Rep. 7, 16642 (2017).
    • (2017) Sci. Rep. , vol.7
    • Gunawan, M.1
  • 59
    • 84995563287 scopus 로고    scopus 로고
    • Rodent models of diabetic nephropathy: their utility and limitations
    • COI: 1:CAS:528:DC%2BC1cXhtFWjsbfE, PID: 27881924
    • Kitada, M., Ogura, Y. & Koya, D. Rodent models of diabetic nephropathy: their utility and limitations. Int. J. Nephrol. Renovasc. Dis. 9, 279–290 (2016).
    • (2016) Int. J. Nephrol. Renovasc. Dis. , vol.9 , pp. 279-290
    • Kitada, M.1    Ogura, Y.2    Koya, D.3
  • 60
    • 0036348280 scopus 로고    scopus 로고
    • New insights from the use of pilocarpine and kainate models
    • COI: 1:CAS:528:DC%2BD38XlvVertbs%3D, PID: 12151121
    • Leite, J. P., Garcia-Cairasco, N. & Cavalheiro, E. A. New insights from the use of pilocarpine and kainate models. Epilepsy Res. 50, 93–103 (2002).
    • (2002) Epilepsy Res. , vol.50 , pp. 93-103
    • Leite, J.P.1    Garcia-Cairasco, N.2    Cavalheiro, E.A.3
  • 61
    • 85042523453 scopus 로고    scopus 로고
    • Animal models of l-dopa-induced dyskinesia in Parkinson’s disease
    • Cenci, M. A. & Crossman, A. R. Animal models of l-dopa-induced dyskinesia in Parkinson’s disease. Mov. Disord. 10.1002/mds.27337 (2018).
    • (2018) Mov. Disord.
    • Cenci, M.A.1    Crossman, A.R.2
  • 62
    • 85011310989 scopus 로고    scopus 로고
    • Proximate causes for diet-induced obesity in laboratory mice: a case study
    • COI: 1:STN:280:DC%2BC1c3hsFensw%3D%3D, PID: 28145422
    • Kless, C., Rink, N., Rozman, J. & Klingenspor, M. Proximate causes for diet-induced obesity in laboratory mice: a case study. Eur. J. Clin. Nutr. 71, 306–317 (2017).
    • (2017) Eur. J. Clin. Nutr. , vol.71 , pp. 306-317
    • Kless, C.1    Rink, N.2    Rozman, J.3    Klingenspor, M.4
  • 63
    • 84979084576 scopus 로고    scopus 로고
    • How does circadian rhythm impact salt sensitivity of blood pressure in mice? A study in two close C57Bl/6 substrains
    • PID: 27088730
    • Combe, R. et al. How does circadian rhythm impact salt sensitivity of blood pressure in mice? A study in two close C57Bl/6 substrains. PLoS One 11, e0153472 (2016).
    • (2016) PLoS One , vol.11
    • Combe, R.1
  • 64
    • 84925486506 scopus 로고    scopus 로고
    • Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice
    • COI: 1:CAS:528:DC%2BC2cXhsFOqtbzF, PID: 25238945
    • Dickson, P. E. et al. Association of novelty-related behaviors and intravenous cocaine self-administration in Diversity Outbred mice. Psychopharmacology 232, 1011–1024 (2015).
    • (2015) Psychopharmacology , vol.232 , pp. 1011-1024
    • Dickson, P.E.1
  • 65
    • 84884285784 scopus 로고    scopus 로고
    • Cocaine self-administration behavior in inbred mouse lines segregating different capacities for inhibitory control
    • COI: 1:CAS:528:DC%2BC3sXnslCjurY%3D, PID: 23681162
    • Cervantes, M. C., Laughlin, R. E. & Jentsch, J. D. Cocaine self-administration behavior in inbred mouse lines segregating different capacities for inhibitory control. Psychopharmacology 229, 515–525 (2013).
    • (2013) Psychopharmacology , vol.229 , pp. 515-525
    • Cervantes, M.C.1    Laughlin, R.E.2    Jentsch, J.D.3
  • 66
    • 84991249413 scopus 로고    scopus 로고
    • Genetic background limits generalizability of genotype–phenotype relationships
    • COI: 1:CAS:528:DC%2BC28XhsVykt7jF, PID: 27618673
    • Sittig, L. J. et al. Genetic background limits generalizability of genotype–phenotype relationships. Neuron 91, 1253–1259 (2016).
    • (2016) Neuron , vol.91 , pp. 1253-1259
    • Sittig, L.J.1
  • 67
    • 84862619928 scopus 로고    scopus 로고
    • Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J × 129S1/SvImJ inbred mouse cross
    • COI: 1:CAS:528:DC%2BC38XnsFGqurg%3D, PID: 22371272
    • Chesler, E. J. et al. Quantitative trait loci for sensitivity to ethanol intoxication in a C57BL/6J × 129S1/SvImJ inbred mouse cross. Mamm. Genome 23, 305–321 (2012).
    • (2012) Mamm. Genome , vol.23 , pp. 305-321
    • Chesler, E.J.1
  • 68
    • 0030913779 scopus 로고    scopus 로고
    • The Min mouse: a genetic model for intestinal carcinogenesis
    • COI: 1:STN:280:DyaK2szlsVSntw%3D%3D, PID: 9210266
    • Thompson, M. B. The Min mouse: a genetic model for intestinal carcinogenesis. Toxicol. Pathol. 25, 329–332 (1997).
    • (1997) Toxicol. Pathol. , vol.25 , pp. 329-332
    • Thompson, M.B.1
  • 69
    • 0027363063 scopus 로고
    • Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse
    • COI: 1:CAS:528:DyaK2cXltFersA%3D%3D, PID: 8242739
    • Dietrich, W. F. et al. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 75, 631–639 (1993).
    • (1993) Cell , vol.75 , pp. 631-639
    • Dietrich, W.F.1
  • 70
    • 0028998255 scopus 로고
    • Min-induced intestinal neoplasia
    • COI: 1:CAS:528:DyaK2MXmsVagt7o%3D, PID: 7781071
    • sMin-induced intestinal neoplasia. Cell 81, 957–966 (1995).
    • (1995) Cell , vol.81 , pp. 957-966
    • MacPhee, M.1
  • 71
    • 0029152947 scopus 로고
    • 2 gene in inbred mouse strains
    • COI: 1:CAS:528:DyaK2MXot1Ghtrs%3D, PID: 7673223
    • 2 gene in inbred mouse strains. J. Biol. Chem. 270, 22378–22385 (1995).
    • (1995) J. Biol. Chem. , vol.270 , pp. 22378-22385
    • Kennedy, B.P.1
  • 72
    • 84904638907 scopus 로고    scopus 로고
    • 2 enzymes as pharmacological targets for treatment of disease
    • COI: 1:CAS:528:DC%2BC2cXhtVCjur%2FN, PID: 24907600
    • 2 enzymes as pharmacological targets for treatment of disease. Biochem. Pharmacol. 90, 338–348 (2014).
    • (2014) Biochem. Pharmacol. , vol.90 , pp. 338-348
    • Quach, N.D.1    Arnold, R.D.2    Cummings, B.S.3
  • 73
    • 85015680446 scopus 로고    scopus 로고
    • 2 isoforms as novel targets for prevention and treatment of inflammatory and oncologic diseases
    • COI: 1:CAS:528:DC%2BC28XhvVOhu7bM, PID: 26212262
    • 2 isoforms as novel targets for prevention and treatment of inflammatory and oncologic diseases. Curr. Drug Targets 17, 1940–1962 (2016).
    • (2016) Curr. Drug Targets , vol.17 , pp. 1940-1962
    • Yarla, N.S.1
  • 74
    • 84923825376 scopus 로고    scopus 로고
    • Human cancer growth and therapy in immunodeficient mouse models
    • top073585
    • Shultz, L. D. et al. Human cancer growth and therapy in immunodeficient mouse models. Cold Spring Harb. Protoc. 2014, pdb.top073585 (2014).
    • (2014) Cold Spring Harb. Protoc. , vol.2014
    • Shultz, L.D.1
  • 75
    • 85043580332 scopus 로고    scopus 로고
    • Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy
    • COI: 1:CAS:528:DC%2BC1cXhslWnt7nL, PID: 29146734
    • Wang, M. et al. Humanized mice in studying efficacy and mechanisms of PD-1-targeted cancer immunotherapy. FASEB J. 32, 1537–1549 (2018).
    • (2018) FASEB J. , vol.32 , pp. 1537-1549
    • Wang, M.1
  • 76
    • 85018414262 scopus 로고    scopus 로고
    • Personalized in vitro and in vivo cancer models to guide precision medicine
    • PID: 28331002
    • Pauli, C. et al. Personalized in vitro and in vivo cancer models to guide precision medicine. Cancer Discov. 7, 462–477 (2017).
    • (2017) Cancer Discov. , vol.7 , pp. 462-477
    • Pauli, C.1
  • 77
    • 85007193603 scopus 로고    scopus 로고
    • Patient-derived xenograft (PDX) models in basic and translational breast cancer research
    • COI: 1:CAS:528:DC%2BC2sXpvVWk, PID: 28025748
    • Dobrolecki, L. E. et al. Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer Metastasis Rev. 35, 547–573 (2016).
    • (2016) Cancer Metastasis Rev. , vol.35 , pp. 547-573
    • Dobrolecki, L.E.1
  • 78
    • 85052848010 scopus 로고    scopus 로고
    • Using PDX for preclinical cancer drug discovery: the evolving field
    • Williams, J. A. Using PDX for preclinical cancer drug discovery: the evolving field. J. Clin. Med. 7, 41 (2018).
    • (2018) J. Clin. Med. , vol.7 , pp. 41
    • Williams, J.A.1
  • 79
    • 84942874576 scopus 로고    scopus 로고
    • Development and characterization of bladder cancer patient-derived xenografts for molecularly guided targeted therapy
    • COI: 1:CAS:528:DC%2BC28XkvFOmtQ%3D%3D, PID: 26270481
    • Pan, C. X. et al. Development and characterization of bladder cancer patient-derived xenografts for molecularly guided targeted therapy. PLoS One 10, e0134346 (2015).
    • (2015) PLoS One , vol.10
    • Pan, C.X.1
  • 80
    • 84899707234 scopus 로고    scopus 로고
    • Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment
    • COI: 1:CAS:528:DC%2BC2cXnsFWiu70%3D, PID: 24634382
    • Garralda, E. et al. Integrated next-generation sequencing and avatar mouse models for personalized cancer treatment. Clin. Cancer Res. 20, 2476–2484 (2014).
    • (2014) Clin. Cancer Res. , vol.20 , pp. 2476-2484
    • Garralda, E.1
  • 81
    • 80051588648 scopus 로고    scopus 로고
    • A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer
    • COI: 1:CAS:528:DC%2BC3MXhtFSqtLnM, PID: 21673092
    • Hidalgo, M. et al. A pilot clinical study of treatment guided by personalized tumorgrafts in patients with advanced cancer. Mol. Cancer Ther. 10, 1311–1316 (2011).
    • (2011) Mol. Cancer Ther. , vol.10 , pp. 1311-1316
    • Hidalgo, M.1
  • 82
    • 85040950396 scopus 로고    scopus 로고
    • Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse
    • PID: 29092072
    • Smith, C. L., Blake, J. A., Kadin, J. A., Richardson, J. E. & Bult, C. J. Mouse Genome Database (MGD)-2018: knowledgebase for the laboratory mouse. Nucleic Acids Res. 46(D1), D836–D842 (2018).
    • (2018) Nucleic Acids Res. , vol.46 , Issue.D1 , pp. D836-D842
    • Smith, C.L.1    Blake, J.A.2    Kadin, J.A.3    Richardson, J.E.4    Bult, C.J.5
  • 83
    • 85016154437 scopus 로고    scopus 로고
    • The mouse Gene Expression Database (GXD): 2017 update
    • COI: 1:CAS:528:DC%2BC1cXhslWgsLY%3D, PID: 27899677
    • Finger, J. H. et al. The mouse Gene Expression Database (GXD): 2017 update. Nucleic Acids Res. 45(D1), D730–D736 (2017).
    • (2017) Nucleic Acids Res. , vol.45 , Issue.D1 , pp. D730-D736
    • Finger, J.H.1
  • 84
    • 85034961195 scopus 로고    scopus 로고
    • The Mouse Tumor Biology Database: a comprehensive resource for mouse models of human cancer
    • COI: 1:CAS:528:DC%2BC2sXhslOltbvE, PID: 29092943
    • Krupke, D. M. et al. The Mouse Tumor Biology Database: a comprehensive resource for mouse models of human cancer. Cancer Res. 77, e67–e70 (2017).
    • (2017) Cancer Res. , vol.77 , pp. e67-e70
    • Krupke, D.M.1
  • 85
    • 84876475747 scopus 로고    scopus 로고
    • Manual Gene Ontology annotation workflow at the Mouse Genome Informatics Database
    • COI: 1:CAS:528:DC%2BC3sXisVCjtrc%3D, PID: 23110975
    • Drabkin, H. J. & Blake, J. A. Manual Gene Ontology annotation workflow at the Mouse Genome Informatics Database. Database 2012, bas045 (2012).
    • (2012) Database , vol.2012 , pp. bas045
    • Drabkin, H.J.1    Blake, J.A.2
  • 86
    • 84993949166 scopus 로고    scopus 로고
    • A RATional choice for translational research?
    • PID: 27736742
    • Aitman, T., Dhillon, P. & Geurts, A. M. A RATional choice for translational research? Dis. Model. Mech. 9, 1069–1072 (2016).
    • (2016) Dis. Model. Mech. , vol.9 , pp. 1069-1072
    • Aitman, T.1    Dhillon, P.2    Geurts, A.M.3
  • 87
    • 0026922594 scopus 로고
    • Genetic dissection of autoimmune type I diabetes in the BB rat
    • COI: 1:CAS:528:DyaK3sXlsl2gsA%3D%3D, PID: 1303251
    • Jacob, H. J. et al. Genetic dissection of autoimmune type I diabetes in the BB rat. Nat. Genet. 2, 56–60 (1992).
    • (1992) Nat. Genet. , vol.2 , pp. 56-60
    • Jacob, H.J.1
  • 88
    • 0033979807 scopus 로고    scopus 로고
    • Genetic analysis of inherited hypertension in the rat
    • COI: 1:CAS:528:DC%2BD3cXmtl2jtA%3D%3D, PID: 10617767
    • Rapp, J. P. Genetic analysis of inherited hypertension in the rat. Physiol. Rev. 80, 135–172 (2000).
    • (2000) Physiol. Rev. , vol.80 , pp. 135-172
    • Rapp, J.P.1
  • 89
    • 0029761370 scopus 로고    scopus 로고
    • A genome scan localizes five non-MHC loci controlling collagen-induced arthritis in rats
    • COI: 1:CAS:528:DyaK28Xls1Wjs7w%3D, PID: 8782824
    • Remmers, E. F. et al. A genome scan localizes five non-MHC loci controlling collagen-induced arthritis in rats. Nat. Genet. 14, 82–85 (1996).
    • (1996) Nat. Genet. , vol.14 , pp. 82-85
    • Remmers, E.F.1
  • 90
    • 0031861150 scopus 로고    scopus 로고
    • Genetic identification of multiple loci that control breast cancer susceptibility in the rat
    • COI: 1:CAS:528:DyaK1cXks1ektLo%3D, PID: 9584103
    • Shepel, L. A. et al. Genetic identification of multiple loci that control breast cancer susceptibility in the rat. Genetics 149, 289–299 (1998).
    • (1998) Genetics , vol.149 , pp. 289-299
    • Shepel, L.A.1
  • 91
    • 78549295495 scopus 로고    scopus 로고
    • Gene targeting in the rat: advances and opportunities
    • COI: 1:CAS:528:DC%2BC3cXhsVGis7jJ, PID: 20869786
    • Jacob, H. J., Lazar, J., Dwinell, M. R., Moreno, C. & Geurts, A. M. Gene targeting in the rat: advances and opportunities. Trends Genet. 26, 510–518 (2010).
    • (2010) Trends Genet. , vol.26 , pp. 510-518
    • Jacob, H.J.1    Lazar, J.2    Dwinell, M.R.3    Moreno, C.4    Geurts, A.M.5
  • 92
    • 84994051946 scopus 로고    scopus 로고
    • From rat pathophysiology to genomic medicine: an interview with Howard Jacob
    • PID: 27736743
    • Jacob, H. From rat pathophysiology to genomic medicine: an interview with Howard Jacob. Dis. Model. Mech. 9, 1073–1077 (2016).
    • (2016) Dis. Model. Mech. , vol.9 , pp. 1073-1077
    • Jacob, H.1
  • 93
    • 85019907002 scopus 로고    scopus 로고
    • Cross-species studies of cognition relevant to drug discovery: a translational approach
    • COI: 1:CAS:528:DC%2BC2sXotlaitLo%3D, PID: 28432778
    • Robbins, T. W. Cross-species studies of cognition relevant to drug discovery: a translational approach. Br. J. Pharmacol. 174, 3191–3199 (2017).
    • (2017) Br. J. Pharmacol. , vol.174 , pp. 3191-3199
    • Robbins, T.W.1
  • 94
    • 84943528035 scopus 로고    scopus 로고
    • Proven value of translational research with appropriate animal models to advance breast cancer treatment and save lives: the tamoxifen tale
    • COI: 1:CAS:528:DC%2BC2MXhtlCqsrw%3D, PID: 24912921
    • Jordan, V. C. Proven value of translational research with appropriate animal models to advance breast cancer treatment and save lives: the tamoxifen tale. Br. J. Clin. Pharmacol. 79, 254–267 (2015).
    • (2015) Br. J. Clin. Pharmacol. , vol.79 , pp. 254-267
    • Jordan, V.C.1
  • 95
    • 85053959194 scopus 로고    scopus 로고
    • A successful story of translational orthodontic research: micro-osteoperforation—from experiments to clinical practice
    • Chou, M. Y. & Mani, A. A successful story of translational orthodontic research: micro-osteoperforation—from experiments to clinical practice. APOS Trends Orthod 7, 6–11 (2017).
    • (2017) APOS Trends Orthod , vol.7 , pp. 6-11
    • Chou, M.Y.1    Mani, A.2
  • 96
    • 78049443164 scopus 로고    scopus 로고
    • Cytokine expression and accelerated tooth movement
    • COI: 1:STN:280:DC%2BC3cflsFaksQ%3D%3D, PID: 20639508
    • Teixeira, C. C. et al. Cytokine expression and accelerated tooth movement. J. Dent. Res. 89, 1135–1141 (2010).
    • (2010) J. Dent. Res. , vol.89 , pp. 1135-1141
    • Teixeira, C.C.1
  • 97
    • 0001831070 scopus 로고
    • Winge, Ø. On haplophase and diplophase of some Saccharomycetes. C. R. Trav. Lab. Carlsberg. Ser. Physiol. 21, 77–111 (1935).
    • (1935) Ser. Physiol. , vol.21 , pp. 77-111
    • Winge, O.S.1
  • 98
    • 85053968059 scopus 로고
    • The Yeast Cell: Its Genetics and Cytology (Education Publishers, Saint Louis, MO
    • Lindegren, C.C. The Yeast Cell: Its Genetics and Cytology (Education Publishers, Saint Louis, MO, USA, 1949).
    • (1949) USA
    • Lindegren, C.C.1
  • 99
    • 21944439546 scopus 로고
    • Chromosome maps of Saccharomyces
    • COI: 1:STN:280:DyaG1M%2FntlyjsA%3D%3D, PID: 13644197
    • Lindegren., C. C., Lindegren, G., Shult, E. E. & Desborough, S. Chromosome maps of Saccharomyces. Nature 183, 800–802 (1959).
    • (1959) Nature , vol.183 , pp. 800-802
    • Lindegren, C.C.1    Lindegren, G.2    Shult, E.E.3    Desborough, S.4
  • 100
    • 35348989590 scopus 로고
    • Linkage relationships in Saccharomyces of genes controlling the fermentation of carbohydrates and the synthesis of vitamins, amino acids and nucleic acid components
    • Lindegren, C. C. & Lindegren, G. Linkage relationships in Saccharomyces of genes controlling the fermentation of carbohydrates and the synthesis of vitamins, amino acids and nucleic acid components. Indian Phytopathol. 4, 11–20 (1951).
    • (1951) Indian Phytopathol. , vol.4 , pp. 11-20
    • Lindegren, C.C.1    Lindegren, G.2
  • 101
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 genes
    • COI: 1:CAS:528:DyaK28XmsVWlt7k%3D
    • Goffeau, A. et al. Life with 6000 genes. Science 274, 546–567 (1996).
    • (1996) Science , vol.274 , pp. 546-567
    • Goffeau, A.1
  • 102
    • 0022133409 scopus 로고
    • Functional selection and analysis of yeast centromeric DNA
    • COI: 1:CAS:528:DyaL2MXmtVyjtb8%3D
    • Hieter, P. et al. Functional selection and analysis of yeast centromeric DNA. Cell 42, 913–921 (1985).
    • (1985) Cell , vol.42 , pp. 913-921
    • Hieter, P.1
  • 103
    • 0026705091 scopus 로고
    • The ARS consensus sequence is required for chromosomal origin function in Saccharomyces cerevisiae
    • COI: 1:CAS:528:DyaK38XmsVKmsLg%3D, PID: 360354
    • Deshpande, A. M. & Newlon, C. S. The ARS consensus sequence is required for chromosomal origin function in Saccharomyces cerevisiae. Mol. Cell. Biol. 12, 4305–4313 (1992).
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4305-4313
    • Deshpande, A.M.1    Newlon, C.S.2
  • 104
    • 0028329781 scopus 로고
    • The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics
    • COI: 1:CAS:528:DyaK2MXpsFWr, PID: 1205885
    • Louis, E. J., Naumova, E. S., Lee, A., Naumov, G. & Haber, J. E. The chromosome end in yeast: its mosaic nature and influence on recombinational dynamics. Genetics 136, 789–802 (1994).
    • (1994) Genetics , vol.136 , pp. 789-802
    • Louis, E.J.1    Naumova, E.S.2    Lee, A.3    Naumov, G.4    Haber, J.E.5
  • 105
    • 0030854739 scopus 로고    scopus 로고
    • tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence
    • COI: 1:CAS:528:DyaK2sXhvVahtrk%3D, PID: 146525
    • Lowe, T. M. & Eddy, S. R. tRNAscan-SE: a program for improved detection of transfer RNA genes in genomic sequence. Nucleic Acids Res. 25, 955–964 (1997).
    • (1997) Nucleic Acids Res. , vol.25 , pp. 955-964
    • Lowe, T.M.1    Eddy, S.R.2
  • 106
    • 0033582628 scopus 로고    scopus 로고
    • A computational screen for methylation guide snoRNAs in yeast
    • COI: 1:CAS:528:DyaK1MXhsFehsLs%3D
    • Lowe, T. M. & Eddy, S. R. A computational screen for methylation guide snoRNAs in yeast. Science 283, 1168–1171 (1999).
    • (1999) Science , vol.283 , pp. 1168-1171
    • Lowe, T.M.1    Eddy, S.R.2
  • 107
    • 0032579887 scopus 로고    scopus 로고
    • The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae
    • COI: 1:CAS:528:DyaK1cXisVOlsL4%3D
    • Planta, R. J. & Mager, W. H. The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae. Yeast 14, 471–477 (1998).
    • (1998) Yeast , vol.14 , pp. 471-477
    • Planta, R.J.1    Mager, W.H.2
  • 108
    • 0031832807 scopus 로고    scopus 로고
    • Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence
    • COI: 1:CAS:528:DyaK1cXjt1aksLY%3D
    • Kim, J. M., Vanguri, S., Boeke, J. D., Gabriel, A. & Voytas, D. F. Transposable elements and genome organization: a comprehensive survey of retrotransposons revealed by the complete Saccharomyces cerevisiae genome sequence. Genome Res. 8, 464–478 (1998).
    • (1998) Genome Res. , vol.8 , pp. 464-478
    • Kim, J.M.1    Vanguri, S.2    Boeke, J.D.3    Gabriel, A.4    Voytas, D.F.5
  • 109
    • 0033529707 scopus 로고    scopus 로고
    • Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis
    • COI: 1:CAS:528:DyaK1MXltVelsbo%3D
    • Winzeler, E. A. et al. Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901–906 (1999).
    • (1999) Science , vol.285 , pp. 901-906
    • Winzeler, E.A.1
  • 110
    • 0037173615 scopus 로고    scopus 로고
    • Functional profiling of the Saccharomyces cerevisiae genome
    • COI: 1:CAS:528:DC%2BD38XlsFajt7k%3D, PID: 12140549
    • Giaever, G. et al. Functional profiling of the Saccharomyces cerevisiae genome. Nature 418, 387–391 (2002).
    • (2002) Nature , vol.418 , pp. 387-391
    • Giaever, G.1
  • 111
    • 0142215475 scopus 로고    scopus 로고
    • Global analysis of protein expression in yeast
    • COI: 1:CAS:528:DC%2BD3sXotV2iu7c%3D, PID: 14562106
    • Ghaemmaghami, S. et al. Global analysis of protein expression in yeast. Nature 425, 737–741 (2003).
    • (2003) Nature , vol.425 , pp. 737-741
    • Ghaemmaghami, S.1
  • 112
    • 0142184341 scopus 로고    scopus 로고
    • Global analysis of protein localization in budding yeast
    • COI: 1:CAS:528:DC%2BD3sXotV2iu7g%3D, PID: 14562095
    • Huh, W.-K. et al. Global analysis of protein localization in budding yeast. Nature 425, 686–691 (2003).
    • (2003) Nature , vol.425 , pp. 686-691
    • Huh, W.K.1
  • 113
    • 84989216655 scopus 로고    scopus 로고
    • A global genetic interaction network maps a wiring diagram of cellular function
    • COI: 1:CAS:528:DC%2BC28XhsFamsrrP, PID: 27708008
    • Costanzo, M. et al. A global genetic interaction network maps a wiring diagram of cellular function. Science 353, aaf1420 (2016).
    • (2016) Science , vol.353 , pp. aaf1420
    • Costanzo, M.1
  • 114
    • 75649111192 scopus 로고    scopus 로고
    • The genetic landscape of a cell
    • COI: 1:CAS:528:DC%2BC3cXnt1ahug%3D%3D, PID: 20093466
    • Costanzo, M. et al. The genetic landscape of a cell. Science 327, 425–431 (2010).
    • (2010) Science , vol.327 , pp. 425-431
    • Costanzo, M.1
  • 115
    • 81255197643 scopus 로고    scopus 로고
    • Yeast: an experimental organism for 21st century biology
    • COI: 1:CAS:528:DC%2BC38XitFKgu7c%3D, PID: 22084421
    • Botstein, D. & Fink, G. R. Yeast: an experimental organism for 21st century biology. Genetics 189, 695–704 (2011).
    • (2011) Genetics , vol.189 , pp. 695-704
    • Botstein, D.1    Fink, G.R.2
  • 116
    • 84930578970 scopus 로고    scopus 로고
    • Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies
    • COI: 1:CAS:528:DC%2BC2MXhsVCmtbrK, PID: 26035862
    • Lasserre, J.-P. et al. Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies. Dis. Model. Mech. 8, 509–526 (2015).
    • (2015) Dis. Model. Mech. , vol.8 , pp. 509-526
    • Lasserre, J.P.1
  • 117
    • 44449131125 scopus 로고    scopus 로고
    • Orthology and functional conservation in eukaryotes
    • COI: 1:CAS:528:DC%2BD1cXns1SitA%3D%3D, PID: 17678444
    • Dolinski, K. & Botstein, D. Orthology and functional conservation in eukaryotes. Annu. Rev. Genet. 41, 465–507 (2007).
    • (2007) Annu. Rev. Genet. , vol.41 , pp. 465-507
    • Dolinski, K.1    Botstein, D.2
  • 118
    • 84879404012 scopus 로고    scopus 로고
    • The new modern era of yeast genomics: community sequencing and the resulting annotation of multiple Saccharomyces cerevisiae strains at the Saccharomyces Genome
    • PID: 23487186
    • Engel, S. R. & Cherry, J. M. The new modern era of yeast genomics: community sequencing and the resulting annotation of multiple Saccharomyces cerevisiae strains at the Saccharomyces Genome. Database. Database 2013, bat012 (2013).
    • (2013) Database. Database , vol.2013 , pp. bat012
    • Engel, S.R.1    Cherry, J.M.2
  • 119
    • 70349515584 scopus 로고    scopus 로고
    • Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118
    • PID: 19805302
    • Novo, M. et al. Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118. Proc. Natl Acad. Sci. USA 106, 16333–16338 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 16333-16338
    • Novo, M.1
  • 120
    • 77953211186 scopus 로고    scopus 로고
    • Bulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiae
    • COI: 1:CAS:528:DC%2BC3cXmsVCht7c%3D, PID: 20485559
    • Wenger, J. W., Schwartz, K. & Sherlock, G. Bulk segregant analysis by high-throughput sequencing reveals a novel xylose utilization gene from Saccharomyces cerevisiae. PLoS Genet. 6, e1000942 (2010).
    • (2010) PLoS Genet. , vol.6
    • Wenger, J.W.1    Schwartz, K.2    Sherlock, G.3
  • 121
    • 80052293238 scopus 로고    scopus 로고
    • Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast
    • PID: 21873232
    • Libkind, D. et al. Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast. Proc. Natl Acad. Sci. USA 108, 14539–14544 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 14539-14544
    • Libkind, D.1
  • 122
    • 84930009075 scopus 로고    scopus 로고
    • Systematic humanization of yeast genes reveals conserved functions and genetic modularity
    • COI: 1:CAS:528:DC%2BC2MXosFaksbg%3D, PID: 25999509
    • Kachroo, A. H. et al. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 348, 921–925 (2015).
    • (2015) Science , vol.348 , pp. 921-925
    • Kachroo, A.H.1
  • 123
    • 85027198543 scopus 로고    scopus 로고
    • Systematic bacterialization of yeast genes identifies a near-universally swappable pathway
    • PID: 28661399
    • Kachroo, A. H. et al. Systematic bacterialization of yeast genes identifies a near-universally swappable pathway. eLife 6, e25093 (2017).
    • (2017) eLife , vol.6
    • Kachroo, A.H.1
  • 124
    • 84876665869 scopus 로고    scopus 로고
    • Functional and evolutionary implications of gene orthology
    • COI: 1:CAS:528:DC%2BC3sXltFGjurk%3D, PID: 23552219
    • Gabaldón, T. & Koonin, E. V. Functional and evolutionary implications of gene orthology. Nat. Rev. Genet. 14, 360–366 (2013).
    • (2013) Nat. Rev. Genet. , vol.14 , pp. 360-366
    • Gabaldón, T.1    Koonin, E.V.2
  • 125
    • 85040934728 scopus 로고    scopus 로고
    • Saccharomyces genome database informs human biology
    • PID: 29140510
    • Skrzypek, M. S. et al. Saccharomyces genome database informs human biology. Nucleic Acids Res. 46(D1), D736–D742 (2018).
    • (2018) Nucleic Acids Res. , vol.46 , Issue.D1 , pp. D736-D742
    • Skrzypek, M.S.1
  • 126
    • 85042039775 scopus 로고    scopus 로고
    • What can we learn about human disease from the nematode C. elegans?
    • PID: 29423793
    • Apfeld, J. & Alper, S. What can we learn about human disease from the nematode C. elegans?. Methods Mol. Biol. 1706, 53–75 (2018).
    • (2018) Methods Mol. Biol. , vol.1706 , pp. 53-75
    • Apfeld, J.1    Alper, S.2
  • 127
    • 85010918273 scopus 로고    scopus 로고
    • Neurocalcin delta suppression protects against spinal muscular atrophy in humans and across species by restoring impaired endocytosis
    • COI: 1:CAS:528:DC%2BC2sXhs1Kgtb0%3D, PID: 28132687
    • Riessland, M. et al. Neurocalcin delta suppression protects against spinal muscular atrophy in humans and across species by restoring impaired endocytosis. Am. J. Hum. Genet. 100, 297–315 (2017).
    • (2017) Am. J. Hum. Genet. , vol.100 , pp. 297-315
    • Riessland, M.1
  • 128
    • 0034639940 scopus 로고    scopus 로고
    • A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes
    • COI: 1:CAS:528:DC%2BD3cXivFyksbs%3D, PID: 10767309
    • Culetto, E. & Sattelle, D. B. A role for Caenorhabditis elegans in understanding the function and interactions of human disease genes. Hum. Mol. Genet. 9, 869–877 (2000).
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 869-877
    • Culetto, E.1    Sattelle, D.B.2
  • 129
    • 85019027989 scopus 로고    scopus 로고
    • Genetic kidney diseases: Caenorhabditis elegans as model system
    • COI: 1:CAS:528:DC%2BC2sXnt1Gjtbo%3D, PID: 28484847
    • Ganner, A. & Neumann-Haefelin, E. Genetic kidney diseases: Caenorhabditis elegans as model system. Cell Tissue Res. 369, 105–118 (2017).
    • (2017) Cell Tissue Res. , vol.369 , pp. 105-118
    • Ganner, A.1    Neumann-Haefelin, E.2
  • 130
    • 80054707557 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model system for studying the nuclear lamina and laminopathic diseases
    • PID: 21970988
    • Bank, E. M. & Gruenbaum, Y. Caenorhabditis elegans as a model system for studying the nuclear lamina and laminopathic diseases. Nucleus 2, 350–357 (2011).
    • (2011) Nucleus , vol.2 , pp. 350-357
    • Bank, E.M.1    Gruenbaum, Y.2
  • 131
    • 79959635045 scopus 로고    scopus 로고
    • Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases
    • COI: 1:CAS:528:DC%2BC3MXptFWgtrk%3D, PID: 21669933
    • Lin, J. & Hackam, D. J. Worms, flies and four-legged friends: the applicability of biological models to the understanding of intestinal inflammatory diseases. Dis. Model. Mech. 4, 447–456 (2011).
    • (2011) Dis. Model. Mech. , vol.4 , pp. 447-456
    • Lin, J.1    Hackam, D.J.2
  • 132
    • 84867867191 scopus 로고    scopus 로고
    • What model organisms and interactomics can reveal about the genetics of human obesity
    • COI: 1:CAS:528:DC%2BC38XhsFCltrvN, PID: 22618246
    • Williams, M. J., Almén, M. S., Fredriksson, R. & Schiöth, H. B. What model organisms and interactomics can reveal about the genetics of human obesity. Cell. Mol. Life Sci. 69, 3819–3834 (2012).
    • (2012) Cell. Mol. Life Sci. , vol.69 , pp. 3819-3834
    • Williams, M.J.1    Almén, M.S.2    Fredriksson, R.3    Schiöth, H.B.4
  • 133
    • 84976875290 scopus 로고    scopus 로고
    • WormBase 2016: expanding to enable helminth genomic research
    • COI: 1:CAS:528:DC%2BC2sXhtV2gu7jM, PID: 26578572
    • Howe, K. L. et al. WormBase 2016: expanding to enable helminth genomic research. Nucleic Acids Res. 44(D1), D774–D780 (2016).
    • (2016) Nucleic Acids Res. , vol.44 , Issue.D1 , pp. D774-D780
    • Howe, K.L.1
  • 134
    • 84990187426 scopus 로고    scopus 로고
    • Mechanisms of aging-related proteinopathies in Caenorhabditis elegans
    • COI: 1:CAS:528:DC%2BC28Xhs1ejtbrK, PID: 27713398
    • Kim, D.-K., Kim, T. H. & Lee, S.-J. Mechanisms of aging-related proteinopathies in Caenorhabditis elegans. Exp. Mol. Med. 48, e263 (2016).
    • (2016) Exp. Mol. Med. , vol.48
    • Kim, D.K.1    Kim, T.H.2    Lee, S.J.3
  • 135
    • 84906267591 scopus 로고    scopus 로고
    • Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BC2MXht1OjsLbL, PID: 25250042
    • Alexander, A. G., Marfil, V. & Li, C. Use of Caenorhabditis elegans as a model to study Alzheimer’s disease and other neurodegenerative diseases. Front. Genet. 5, 279 (2014).
    • (2014) Front. Genet. , vol.5 , pp. 279
    • Alexander, A.G.1    Marfil, V.2    Li, C.3
  • 136
    • 85037626540 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model system for target identification and drug screening against neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BC2sXhvF2gurvP, PID: 29208474
    • Ma, L. et al. Caenorhabditis elegans as a model system for target identification and drug screening against neurodegenerative diseases. Eur. J. Pharmacol. 819, 169–180 (2018).
    • (2018) Eur. J. Pharmacol. , vol.819 , pp. 169-180
    • Ma, L.1
  • 137
    • 85038815715 scopus 로고    scopus 로고
    • Genetic and pharmacological discovery for Alzheimer’s disease using Caenorhabditis elegans
    • COI: 1:CAS:528:DC%2BC2sXhs1emtL%2FK, PID: 29022701
    • Griffin, E. F., Caldwell, K. A. & Caldwell, G. A. Genetic and pharmacological discovery for Alzheimer’s disease using Caenorhabditis elegans. ACS Chem. Neurosci. 8, 2596–2606 (2017).
    • (2017) ACS Chem. Neurosci. , vol.8 , pp. 2596-2606
    • Griffin, E.F.1    Caldwell, K.A.2    Caldwell, G.A.3
  • 138
    • 84855222491 scopus 로고    scopus 로고
    • Invertebrate models of lysosomal storage disease: what have we learned so far?
    • COI: 1:CAS:528:DC%2BC3MXhsFamsr3O, PID: 22038288
    • Hindle, S., Hebbar, S. & Sweeney, S. T. Invertebrate models of lysosomal storage disease: what have we learned so far? Invert. Neurosci. 11, 59–71 (2011).
    • (2011) Invert. Neurosci. , vol.11 , pp. 59-71
    • Hindle, S.1    Hebbar, S.2    Sweeney, S.T.3
  • 139
    • 49649113915 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model for lysosomal storage disorders
    • COI: 1:CAS:528:DC%2BD1cXnsFOrtrw%3D, PID: 18501720
    • de Voer, G., Peters, D. & Taschner, P. E. M. Caenorhabditis elegans as a model for lysosomal storage disorders. Biochim. Biophys. Acta 1782, 433–446 (2008).
    • (2008) Biochim. Biophys. Acta , vol.1782 , pp. 433-446
    • de Voer, G.1    Peters, D.2    Taschner, P.E.M.3
  • 140
    • 0001466626 scopus 로고
    • The biology and use of zebrafish Brachydanio rerio in fisheries research: a literature review
    • Laale, H. The biology and use of zebrafish Brachydanio rerio in fisheries research: a literature review. J. Fish Biol. 10, 121–173 (1977).
    • (1977) J. Fish Biol. , vol.10 , pp. 121-173
    • Laale, H.1
  • 141
    • 0035834358 scopus 로고    scopus 로고
    • Zebrafish—the canonical vertebrate
    • COI: 1:CAS:528:DC%2BD3MXotlKntbY%3D, PID: 11701913
    • Fishman, M. C. Zebrafish—the canonical vertebrate. Science 294, 1290–1291 (2001).
    • (2001) Science , vol.294 , pp. 1290-1291
    • Fishman, M.C.1
  • 142
    • 84903993789 scopus 로고    scopus 로고
    • Zebrafish models in translational research: tipping the scales toward advancements in human health
    • COI: 1:CAS:528:DC%2BC2cXhslensrvI, PID: 24973743
    • Phillips, J. B. & Westerfield, M. Zebrafish models in translational research: tipping the scales toward advancements in human health. Dis. Model. Mech. 7, 739–743 (2014).
    • (2014) Dis. Model. Mech. , vol.7 , pp. 739-743
    • Phillips, J.B.1    Westerfield, M.2
  • 143
    • 34247186766 scopus 로고    scopus 로고
    • Animal models of human disease: zebrafish swim into view
    • COI: 1:CAS:528:DC%2BD2sXktlSltLk%3D, PID: 17440532
    • Lieschke, G. J. & Currie, P. D. Animal models of human disease: zebrafish swim into view. Nat. Rev. Genet. 8, 353–367 (2007).
    • (2007) Nat. Rev. Genet. , vol.8 , pp. 353-367
    • Lieschke, G.J.1    Currie, P.D.2
  • 144
    • 84876528441 scopus 로고    scopus 로고
    • ZFIN, the Zebrafish Model Organism Database: increased support for mutants and transgenics
    • COI: 1:CAS:528:DC%2BC38XhvV2ksb3J, PID: 23074187
    • Howe, D. G. D. G. et al. ZFIN, the Zebrafish Model Organism Database: increased support for mutants and transgenics. Nucleic Acids Res. 41, D854–D860 (2013).
    • (2013) Nucleic Acids Res. , vol.41 , pp. D854-D860
    • Howe, D.G.D.G.1
  • 145
    • 85028358369 scopus 로고    scopus 로고
    • Zebrafish models of human disease: gaining insight into human disease at ZFIN
    • PID: 28838067
    • Bradford, Y. M. et al. Zebrafish models of human disease: gaining insight into human disease at ZFIN. ILAR J. 58, 4–16 (2017).
    • (2017) ILAR J. , vol.58 , pp. 4-16
    • Bradford, Y.M.1
  • 146
    • 84870035489 scopus 로고    scopus 로고
    • Zebrafish models flex their muscles to shed light on muscular dystrophies
    • COI: 1:CAS:528:DC%2BC3sXnt1Krsw%3D%3D, PID: 23115202
    • Berger, J. & Currie, P. D. Zebrafish models flex their muscles to shed light on muscular dystrophies. Dis. Model. Mech. 5, 726–732 (2012).
    • (2012) Dis. Model. Mech. , vol.5 , pp. 726-732
    • Berger, J.1    Currie, P.D.2
  • 147
    • 79952763456 scopus 로고    scopus 로고
    • Modeling Diamond Blackfan anemia in the zebrafish
    • PID: 21435504
    • Taylor, A. M. & Zon, L. I. Modeling Diamond Blackfan anemia in the zebrafish. Semin. Hematol. 48, 81–88 (2011).
    • (2011) Semin. Hematol. , vol.48 , pp. 81-88
    • Taylor, A.M.1    Zon, L.I.2
  • 148
    • 85037058930 scopus 로고    scopus 로고
    • Pyridoxine-dependent epilepsy in zebrafish caused by Aldh7a1 deficiency
    • PID: 29061647
    • Pena, I. A. et al. Pyridoxine-dependent epilepsy in zebrafish caused by Aldh7a1 deficiency. Genetics 207, 1501–1518 (2017).
    • (2017) Genetics , vol.207 , pp. 1501-1518
    • Pena, I.A.1
  • 149
    • 85009344273 scopus 로고    scopus 로고
    • Q63X mutant zebrafish
    • COI: 1:CAS:528:DC%2BC2sXhtFOgsLs%3D, PID: 28062374
    • Q63X mutant zebrafish. J. Proteomics 154, 128–133 (2017).
    • (2017) J. Proteomics , vol.154 , pp. 128-133
    • Cortelazzo, A.1
  • 150
    • 84880589894 scopus 로고    scopus 로고
    • The first mecp2-null zebrafish model shows altered motor behaviors
    • PID: 23874272
    • Pietri, T. et al. The first mecp2-null zebrafish model shows altered motor behaviors. Front. Neural Circuits 7, 118 (2013).
    • (2013) Front. Neural Circuits , vol.7 , pp. 118
    • Pietri, T.1
  • 151
    • 84932102175 scopus 로고    scopus 로고
    • Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish
    • COI: 1:CAS:528:DC%2BC2MXht1ejsr7L, PID: 25948585
    • Gao, H. et al. Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish. J. Cell Sci. 128, 2340–2350 (2015).
    • (2015) J. Cell Sci. , vol.128 , pp. 2340-2350
    • Gao, H.1
  • 152
    • 85014613338 scopus 로고    scopus 로고
    • A zebrafish loss-of-function model for human CFAP53 mutations reveals its specific role in laterality organ function
    • COI: 1:CAS:528:DC%2BC28XhtlWks7o%3D, PID: 26531781
    • Noël, E. S. et al. A zebrafish loss-of-function model for human CFAP53 mutations reveals its specific role in laterality organ function. Hum. Mutat. 37, 194–200 (2016).
    • (2016) Hum. Mutat. , vol.37 , pp. 194-200
    • Noël, E.S.1
  • 153
    • 84857505835 scopus 로고    scopus 로고
    • An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis
    • COI: 1:CAS:528:DC%2BC38XitFKhsL4%3D, PID: 22285814
    • Cast, A. E., Gao, C., Amack, J. D. & Ware, S. M. An essential and highly conserved role for Zic3 in left–right patterning, gastrulation and convergent extension morphogenesis. Dev. Biol. 364, 22–31 (2012).
    • (2012) Dev. Biol. , vol.364 , pp. 22-31
    • Cast, A.E.1    Gao, C.2    Amack, J.D.3    Ware, S.M.4
  • 154
    • 85002397981 scopus 로고    scopus 로고
    • Expression of cataract-linked gamma-crystallin variants in zebrafish reveals a proteostasis network that senses protein stability
    • COI: 1:CAS:528:DC%2BC28XhvFyrsbbF, PID: 27770023
    • Wu, S.-Y. et al. Expression of cataract-linked gamma-crystallin variants in zebrafish reveals a proteostasis network that senses protein stability. J. Biol. Chem. 291, 25387–25397 (2016).
    • (2016) J. Biol. Chem. , vol.291 , pp. 25387-25397
    • Wu, S.Y.1
  • 155
    • 85020618729 scopus 로고    scopus 로고
    • Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy
    • PID: 28577986
    • Hunyadi, B., Siekierska, A., Sourbron, J., Copmans, D. & de Witte, P. A. M. Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy. J. Neurosci. Methods 287, 13–24 (2017).
    • (2017) J. Neurosci. Methods , vol.287 , pp. 13-24
    • Hunyadi, B.1    Siekierska, A.2    Sourbron, J.3    Copmans, D.4    de Witte, P.A.M.5
  • 156
    • 84902344447 scopus 로고    scopus 로고
    • Effects of 6-hydroxydopamine exposure on motor activity and biochemical expression in zebrafish (Danio rerio) larvae
    • COI: 1:CAS:528:DC%2BC2cXpsFKgt7o%3D, PID: 24720843
    • Feng, C.-W. et al. Effects of 6-hydroxydopamine exposure on motor activity and biochemical expression in zebrafish (Danio rerio) larvae. Zebrafish 11, 227–239 (2014).
    • (2014) Zebrafish , vol.11 , pp. 227-239
    • Feng, C.W.1
  • 157
    • 84978116690 scopus 로고    scopus 로고
    • Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network
    • COI: 1:CAS:528:DC%2BC28XmvFOku7c%3D, PID: 27064726
    • Díaz-Casado, M. E. et al. Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the parkin/PINK1/DJ-1/MUL1 network. J. Pineal Res. 61, 96–107 (2016).
    • (2016) J. Pineal Res. , vol.61 , pp. 96-107
    • Díaz-Casado, M.E.1
  • 158
    • 84883885889 scopus 로고    scopus 로고
    • The emerging use of zebrafish to model metabolic disease
    • COI: 1:CAS:528:DC%2BC3sXhs1yrsrnP, PID: 24046387
    • Seth, A., Stemple, D. L. & Barroso, I. The emerging use of zebrafish to model metabolic disease. Dis. Model. Mech. 6, 1080–1088 (2013).
    • (2013) Dis. Model. Mech. , vol.6 , pp. 1080-1088
    • Seth, A.1    Stemple, D.L.2    Barroso, I.3
  • 159
    • 84862105795 scopus 로고    scopus 로고
    • Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish
    • COI: 1:CAS:528:DC%2BC38XnvFaisrk%3D, PID: 22623957
    • Chu, C.-Y. et al. Overexpression of Akt1 enhances adipogenesis and leads to lipoma formation in zebrafish. PLoS One 7, e36474 (2012).
    • (2012) PLoS One , vol.7
    • Chu, C.Y.1
  • 160
    • 34347380896 scopus 로고    scopus 로고
    • Creation of a genetic model of obesity in a teleost
    • COI: 1:CAS:528:DC%2BD2sXnvVags70%3D, PID: 17341684
    • Song, Y. & Cone, R. D. Creation of a genetic model of obesity in a teleost. FASEB J. 21, 2042–2049 (2007).
    • (2007) FASEB J. , vol.21 , pp. 2042-2049
    • Song, Y.1    Cone, R.D.2
  • 161
    • 77958063526 scopus 로고    scopus 로고
    • Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity
    • COI: 1:CAS:528:DC%2BC3cXhsVSqsrnF, PID: 20961460
    • Oka, T. et al. Diet-induced obesity in zebrafish shares common pathophysiological pathways with mammalian obesity. BMC Physiol. 10, 21 (2010).
    • (2010) BMC Physiol. , vol.10
    • Oka, T.1
  • 162
    • 84958665135 scopus 로고    scopus 로고
    • Morphological differences in adipose tissue and changes in BDNF/Trkb expression in brain and gut of a diet induced obese zebrafish model
    • PID: 26617157
    • Montalbano, G. et al. Morphological differences in adipose tissue and changes in BDNF/Trkb expression in brain and gut of a diet induced obese zebrafish model. Ann. Anat. 204, 36–44 (2016).
    • (2016) Ann. Anat. , vol.204 , pp. 36-44
    • Montalbano, G.1
  • 163
    • 65549123510 scopus 로고    scopus 로고
    • Zebrafish: a complete animal model for in vivo drug discovery and development
    • COI: 1:CAS:528:DC%2BD1MXks1SqtL0%3D
    • Chakraborty, C., Hsu, C. H., Wen, Z. H., Lin, C. S. & Agoramoorthy, G. Zebrafish: a complete animal model for in vivo drug discovery and development. Curr. Drug Metab. 10, 116–124 (2009).
    • (2009) Curr. Drug Metab. , vol.10 , pp. 116-124
    • Chakraborty, C.1    Hsu, C.H.2    Wen, Z.H.3    Lin, C.S.4    Agoramoorthy, G.5
  • 164
    • 2342475704 scopus 로고    scopus 로고
    • Zebrafish: a preclinical model for drug screening
    • COI: 1:CAS:528:DC%2BD38XptVejsbc%3D, PID: 15090155
    • Parng, C., Seng, W. L., Semino, C. & McGrath, P. Zebrafish: a preclinical model for drug screening. Assay Drug Dev. Technol. 1, 41–48 (2002).
    • (2002) Assay Drug Dev. Technol. , vol.1 , pp. 41-48
    • Parng, C.1    Seng, W.L.2    Semino, C.3    McGrath, P.4
  • 165
    • 84989325743 scopus 로고    scopus 로고
    • Zebrafish small molecule screens: taking the phenotypic plunge
    • COI: 1:CAS:528:DC%2BC28Xhs1SltrnI, PID: 27721960
    • Williams, C. H. & Hong, C. C. Zebrafish small molecule screens: taking the phenotypic plunge. Comput. Struct. Biotechnol. J. 14, 350–356 (2016).
    • (2016) Comput. Struct. Biotechnol. J. , vol.14 , pp. 350-356
    • Williams, C.H.1    Hong, C.C.2
  • 166
    • 85004028284 scopus 로고    scopus 로고
    • Using zebrafish models of leukemia to streamline drug screening and discovery
    • COI: 1:CAS:528:DC%2BC28XhvVShsLrN, PID: 27720937
    • Deveau, A. P., Bentley, V. L. & Berman, J. N. Using zebrafish models of leukemia to streamline drug screening and discovery. Exp. Hematol. 45, 1–9 (2017).
    • (2017) Exp. Hematol. , vol.45 , pp. 1-9
    • Deveau, A.P.1    Bentley, V.L.2    Berman, J.N.3
  • 167
    • 79953064886 scopus 로고    scopus 로고
    • DHODH modulates transcriptional elongation in the neural crest and melanoma
    • COI: 1:CAS:528:DC%2BC3MXjvVOhtLk%3D, PID: 21430780
    • White, R. M. et al. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature 471, 518–522 (2011).
    • (2011) Nature , vol.471 , pp. 518-522
    • White, R.M.1
  • 168
    • 84921899609 scopus 로고    scopus 로고
    • Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen
    • COI: 1:CAS:528:DC%2BC2MXit1Kqsrs%3D, PID: 25385118
    • Ordas, A. et al. Testing tuberculosis drug efficacy in a zebrafish high-throughput translational medicine screen. Antimicrob. Agents Chemother. 59, 753–762 (2015).
    • (2015) Antimicrob. Agents Chemother. , vol.59 , pp. 753-762
    • Ordas, A.1
  • 169
    • 85028588826 scopus 로고    scopus 로고
    • The power of zebrafish in personalised medicine
    • PID: 28840558
    • Baxendale, S., van Eeden, F. & Wilkinson, R. The power of zebrafish in personalised medicine. Adv. Exp. Med. Biol. 1007, 179–197 (2017).
    • (2017) Adv. Exp. Med. Biol. , vol.1007 , pp. 179-197
    • Baxendale, S.1    van Eeden, F.2    Wilkinson, R.3
  • 170
    • 85034583731 scopus 로고    scopus 로고
    • Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer
    • PID: 29141689
    • Wu, J.-Q. et al. Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer. J. Exp. Clin. Cancer Res. 36, 160 (2017).
    • (2017) J. Exp. Clin. Cancer Res. , vol.36 , pp. 160
    • Wu, J.Q.1
  • 171
    • 84982794761 scopus 로고    scopus 로고
    • Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors
    • COI: 1:CAS:528:DC%2BC28Xht1KrtLzE, PID: 27481363
    • Gaudenzi, G. et al. Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors. Endocrine 57, 214–219 (2017).
    • (2017) Endocrine , vol.57 , pp. 214-219
    • Gaudenzi, G.1
  • 172
    • 84878893739 scopus 로고    scopus 로고
    • bioNerDS: exploring bioinformatics’ database and software use through literature mining
    • PID: 23768135
    • Duck, G., Nenadic, G., Brass, A., Robertson, D. L. & Stevens, R. bioNerDS: exploring bioinformatics’ database and software use through literature mining. BMC Bioinformatics 14, 194 (2013).
    • (2013) BMC Bioinformatics , vol.14
    • Duck, G.1    Nenadic, G.2    Brass, A.3    Robertson, D.L.4    Stevens, R.5
  • 174
    • 85034437625 scopus 로고    scopus 로고
    • Regeneration of the entire human epidermis using transgenic stem cells
    • COI: 1:CAS:528:DC%2BC2sXhslygtLvE, PID: 29144448
    • Hirsch, T. et al. Regeneration of the entire human epidermis using transgenic stem cells. Nature 551, 327–332 (2017).
    • (2017) Nature , vol.551 , pp. 327-332
    • Hirsch, T.1
  • 175
    • 84947907035 scopus 로고    scopus 로고
    • Next-generation diagnostics and disease-gene discovery with the Exomiser
    • COI: 1:CAS:528:DC%2BC2MXhslyhurvM, PID: 26562621
    • Smedley, D. et al. Next-generation diagnostics and disease-gene discovery with the Exomiser. Nat. Protoc. 10, 2004–2015 (2015).
    • (2015) Nat. Protoc. , vol.10 , pp. 2004-2015
    • Smedley, D.1
  • 176
    • 84975063087 scopus 로고    scopus 로고
    • Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency
    • COI: 1:CAS:528:DC%2BC28XhtVWltbfO, PID: 26562225
    • Bone, W. P. et al. Computational evaluation of exome sequence data using human and model organism phenotypes improves diagnostic efficiency. Genet. Med. 18, 608–617 (2016).
    • (2016) Genet. Med. , vol.18 , pp. 608-617
    • Bone, W.P.1
  • 177
    • 85015982066 scopus 로고    scopus 로고
    • The Human Phenotype Ontology in 2017
    • COI: 1:CAS:528:DC%2BC1cXhslWhurc%3D, PID: 27899602
    • Köhler, S. et al. The Human Phenotype Ontology in 2017. Nucleic Acids Res. 45(D1), D865–D876 (2017).
    • (2017) Nucleic Acids Res. , vol.45 , Issue.D1 , pp. D865-D876
    • Köhler, S.1
  • 178
    • 84938965200 scopus 로고    scopus 로고
    • The genetic basis of Mendelian phenotypes: discoveries, challenges, and opportunities
    • COI: 1:CAS:528:DC%2BC2MXhtFCktbfJ, PID: 26166479
    • Chong, J. X. et al. The genetic basis of Mendelian phenotypes: discoveries, challenges, and opportunities. Am. J. Hum. Genet. 97, 199–215 (2015).
    • (2015) Am. J. Hum. Genet. , vol.97 , pp. 199-215
    • Chong, J.X.1
  • 179
    • 85024925502 scopus 로고    scopus 로고
    • From animal models to human disease: a genetic approach for personalized medicine in ALS
    • COI: 1:CAS:528:DC%2BC2sXhs1GhsLrK, PID: 27400686
    • Picher-Martel, V., Valdmanis, P. N., Gould, P. V., Julien, J. P. & Dupré, N. From animal models to human disease: a genetic approach for personalized medicine in ALS. Acta Neuropathol. Commun. 4, 70 (2016).
    • (2016) Acta Neuropathol. Commun. , vol.4 , pp. 70
    • Picher-Martel, V.1    Valdmanis, P.N.2    Gould, P.V.3    Julien, J.P.4    Dupré, N.5
  • 180
    • 77951234323 scopus 로고    scopus 로고
    • Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases
    • COI: 1:CAS:528:DC%2BC3cXktFGlsrg%3D, PID: 20147746
    • Renna, M., Jimenez-Sanchez, M., Sarkar, S. & Rubinsztein, D. C. Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases. J. Biol. Chem. 285, 11061–11067 (2010).
    • (2010) J. Biol. Chem. , vol.285 , pp. 11061-11067
    • Renna, M.1    Jimenez-Sanchez, M.2    Sarkar, S.3    Rubinsztein, D.C.4
  • 181
    • 84881551205 scopus 로고    scopus 로고
    • Use of model organisms for the study of neuronal ceroid lipofuscinosis
    • COI: 1:CAS:528:DC%2BC3sXivF2qt7k%3D, PID: 23338040
    • Bond, M., Holthaus, S.-M. K., Tammen, I., Tear, G. & Russell, C. Use of model organisms for the study of neuronal ceroid lipofuscinosis. Biochim. Biophys. Acta 1832, 1842–1865 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1832 , pp. 1842-1865
    • Bond, M.1    Holthaus, S.M.K.2    Tammen, I.3    Tear, G.4    Russell, C.5
  • 182
    • 84962269370 scopus 로고    scopus 로고
    • The FAIR Guiding Principles for scientific data management and stewardship
    • PID: 4792175
    • Wilkinson, M. D. et al. The FAIR Guiding Principles for scientific data management and stewardship. Sci. Data 3, 160018 (2016).
    • (2016) Sci. Data , vol.3
    • Wilkinson, M.D.1
  • 183
    • 80052142945 scopus 로고    scopus 로고
    • An integrative approach to ortholog prediction for disease-focused and other functional studies
    • PID: 21880147
    • Hu, Y. et al. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics 12, 357 (2011).
    • (2011) BMC Bioinformatics , vol.12
    • Hu, Y.1
  • 184
    • 84878682420 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) project
    • COI: 1:CAS:528:DC%2BC3sXotlGls74%3D
    • GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 45, 580–585 (2013).
    • (2013) Nat. Genet. , vol.45 , pp. 580-585
  • 185
    • 85019763343 scopus 로고    scopus 로고
    • DATS, the data tag suite to enable discoverability of datasets
    • PID: 28585923
    • Sansone, S.-A. et al. DATS, the data tag suite to enable discoverability of datasets. Sci. Data 4, 170059 (2017).
    • (2017) Sci. Data , vol.4
    • Sansone, S.A.1
  • 186
    • 85015207553 scopus 로고    scopus 로고
    • I’ll take that to go: big data bags and minimal identifiers for exchange of large, complex datasets
    • Chard, K. et al. I’ll take that to go: big data bags and minimal identifiers for exchange of large, complex datasets. in IEEE International Conference on Big Data (Big Data) 319–328 (2016).
    • (2016) in IEEE International Conference on Big Data (Big Data) , pp. 319-328
    • Chard, K.1
  • 187
    • 58349111875 scopus 로고    scopus 로고
    • AmiGO: online access to ontology and annotation data
    • COI: 1:CAS:528:DC%2BD1MXntFWiuw%3D%3D
    • Carbon, S. et al. AmiGO: online access to ontology and annotation data. Bioinformatics 25, 288–289 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 288-289
    • Carbon, S.1
  • 188
    • 85053960425 scopus 로고    scopus 로고
    • The anatomy of phenotype ontologies: principles, properties and applications
    • (2017), &
    • Gkoutos, G.V., Schofield, P.N. & Hoehndorf, R. The anatomy of phenotype ontologies: principles, properties and applications. Brief. Bioinform. 10.1093/bib/bbx035 (2017).
    • Brief. Bioinform.
    • Gkoutos, G.V.1    Schofield, P.N.2    Hoehndorf, R.3
  • 189
    • 38549118463 scopus 로고    scopus 로고
    • The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes
    • COI: 1:CAS:528:DC%2BD1cXhtVSqsLs%3D
    • Sprague, J. et al. The Zebrafish Information Network: the zebrafish model organism database provides expanded support for genotypes and phenotypes. Nucleic Acids Res. 36, D768–D772 (2008).
    • (2008) Nucleic Acids Res. , vol.36 , pp. D768-D772
    • Sprague, J.1
  • 190
    • 84923212727 scopus 로고    scopus 로고
    • Clinical interpretation of CNVs with cross-species phenotype data
    • COI: 1:CAS:528:DC%2BC2MXit1CisL8%3D, PID: 4501634
    • Köhler, S. et al. Clinical interpretation of CNVs with cross-species phenotype data. J. Med. Genet. 51, 766–772 (2014).
    • (2014) J. Med. Genet. , vol.51 , pp. 766-772
    • Köhler, S.1
  • 191
    • 84923169896 scopus 로고    scopus 로고
    • Construction and accessibility of a cross-species phenotype ontology along with gene annotations for biomedical research
    • PID: 24358873
    • Köhler, S. et al. Construction and accessibility of a cross-species phenotype ontology along with gene annotations for biomedical research. F1000Res. 2, 30 (2013).
    • (2013) F1000Res. , vol.2 , pp. 30
    • Köhler, S.1
  • 193
    • 85040355501 scopus 로고    scopus 로고
    • Improving the interoperability of biomedical ontologies with compound alignments
    • PID: 5761129
    • Oliveira, D. & Pesquita, C. Improving the interoperability of biomedical ontologies with compound alignments. J. Biomed. Semantics 9, 1 (2018).
    • (2018) J. Biomed. Semantics , vol.9 , pp. 1
    • Oliveira, D.1    Pesquita, C.2
  • 194
    • 85053980482 scopus 로고    scopus 로고
    • making phenotype profiles FAIR++ for disease diagis and discovery. FigShare
    • Haendel, M. Phenopackets: making phenotype profiles FAIR++ for disease diagnosis and discovery. FigShare 10.6084/m9.figshare.3180898.v1 (2016).
    • (2016)
    • Haendel, M.P.1
  • 195
    • 84896877227 scopus 로고    scopus 로고
    • A future of the model organism model
    • PID: 24577733
    • Rine, J. A future of the model organism model. Mol. Biol. Cell 25, 549–553 (2014).
    • (2014) Mol. Biol. Cell , vol.25 , pp. 549-553
    • Rine, J.1


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