Severity of Demyelinating and Axonal Neuropathy Mouse Models Is Modified by Genes Affecting Structure and Function of Peripheral Nodes

Cell Reports

Volumn 18, Issue 13, 2017, Pages 3178-3191

  Morelli, Kathryn H ^a,b   Seburn, Kevin L ^a   Schroeder, David G ^a   Spaulding, Emily L ^a,b   Dionne, Loiuse A ^a   Cox, Gregory A ^a,b   Burgess, Robert W ^a,b  

^a JACKSON LABORATORY   (United States)

^b UNIVERSITY OF MAINE   (United States)

Author keywords

axons; Charcot Marie Tooth disease; degeneration; genetic modifiers; hereditary sensory; length constant; motor neuropathy

Indexed keywords

CELL ADHESION MOLECULE; DNA; GENOMIC DNA; MYELIN; SODIUM CHANNEL NAV1.6; CARRIER PROTEIN; NRCAM PROTEIN, MOUSE; SCN8A PROTEIN, MOUSE; SH3TC2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXON; AXONAL NEUROPATHY; CONTROLLED STUDY; DEMYELINATING NEUROPATHY; DISEASE COURSE; DISEASE SEVERITY; DNA MODIFICATION; GENE INTERACTION; GENE LOCUS; GENE MAPPING; GENE MUTATION; GENETIC VARIABILITY; HEREDITARY MOTOR SENSORY NEUROPATHY; HETEROZYGOSITY; HOMOZYGOSITY; MOTOR NEUROPATHY; MOUSE; MUSCLE ATROPHY; MUSCLE WEAKNESS; NERVE CONDUCTION; NERVE FIBER DEGENERATION; NERVE FUNCTION; NEUROMUSCULAR JUNCTION; NEUROPATHY; NONHUMAN; PERIPHERAL NERVE; PERIPHERAL NERVOUS SYSTEM; PERIPHERAL NEUROPATHY; PHENOTYPE; POLYNEUROPATHY; RANVIER NODE; SENSORY NEUROPATHY; VOLTAGE CLAMP TECHNIQUE; ANIMAL; C57BL MOUSE; DEMYELINATING DISEASE; DISEASE MODEL; GENETICS; HETEROZYGOTE; METABOLISM; MUTATION; PATHOLOGY;

ANIMALS; AXONS; CARRIER PROTEINS; CELL ADHESION MOLECULES; CHARCOT-MARIE-TOOTH DISEASE; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; HETEROZYGOTE; MICE, INBRED C57BL; MUTATION; NAV1.6 VOLTAGE-GATED SODIUM CHANNEL; NEUROMUSCULAR JUNCTION; PERIPHERAL NERVES;

EID: 85016288977     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.03.009     Document Type: Article

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